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Posters A-Z Abdelmessih, Mario Deciphering the combinatorial code shaping mRNA stability during development 52 Achour, Cyrinne Elucidating the role of the methyltransferase METTL3 in breast cancer 53 Ahmed, Nabeel Wide variability of transcriptome-wide translation rates is encoded in the sequence of the mRNA 54 Akgul, Bunyamin Transcriptomics profiling of circular RNAs in apoptotic HeLa cells 55 Akgul, Bunyamin Presenter: Erdogan, Ipek Investigation of The Effect of TNFRSF10b-As lncRNA on Cell Proliferation 56 Akimitsu, Nobuyoshi Identification of functional targets reveals that suppression of Pumilio-mediated mRNA decay increases cell resistance to DNA damage in human cells 57 Albihlal, Waleed Distinct functions of the yeast phosphofructokinase paralogs as posttranscriptional regulators of gene expression 58 Almasoudi, Kholoud Investigation of the consequences of the downregulation of NMD factors occurring during neuronal differentiation of an adult neural stem cell line 59 Ascensão-Ferreira, Mariana Profiling the alternative splicing landscape of senescent cells 60 Asfaha, Jonathan Mitotic Control of mRNA Decay 61 Badis, Gwenael Antisense transcriptional interference mediates condition-specific gene repression in budding yeast 62 Page 17

Abdelmessih, Mario Deciphering the combinatorial code ... · EMBO|EMBL Symposium: The Complex Life of RNA Bajak, Kathrin A novel post-transcriptional repressive complex required for

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Posters A-Z

Abdelmessih, Mario Deciphering the combinatorial code shaping mRNA stability during development

52

Achour, Cyrinne Elucidating the role of the methyltransferase METTL3 in breast cancer 53

Ahmed, Nabeel Wide variability of transcriptome-wide translation rates is encoded in the sequence of the mRNA

54

Akgul, Bunyamin Transcriptomics profiling of circular RNAs in apoptotic HeLa cells 55

Akgul, Bunyamin Presenter: Erdogan, Ipek Investigation of The Effect of TNFRSF10b-As lncRNA on Cell Proliferation

56

Akimitsu, Nobuyoshi Identification of functional targets reveals that suppression of Pumilio-mediated mRNA decay increases cell resistance to DNA damage in human cells

57

Albihlal, Waleed Distinct functions of the yeast phosphofructokinase paralogs as posttranscriptional regulators of gene expression

58

Almasoudi, Kholoud Investigation of the consequences of the downregulation of NMD factors occurring during neuronal differentiation of an adult neural stem cell line

59

Ascensão-Ferreira, Mariana Profiling the alternative splicing landscape of senescent cells 60

Asfaha, Jonathan Mitotic Control of mRNA Decay 61

Badis, Gwenael Antisense transcriptional interference mediates condition-specific gene repression in budding yeast

62

Page 17

EMBO|EMBL Symposium: The Complex Life of RNA

Bajak, Kathrin A novel post-transcriptional repressive complex required for cell-cycle progression

63

Bakthavachalu, Baskar TRIBE analysis of Drosophila Ataxin-2 mRNA targets from fly brain 64

Baloun, Jiri miRNA screening of infantile and adult rat hippocampal tissues in acute phase of epilepsy

65

Batista, Andreia Microglia Can Influence RNA Translation in Hippocampal Axons in Response to a ß-Amyloid Neurodegenerative Signal

66

Batista, Andreia Presenter: Baleriola, Jimena Regulation of local translation in neurons by astrocytes 67

Bazzini, Ariel Codon optimality in vertebrates: Hidden regulatory code within the genetic code

68

Bechara, Sebastian Investigating the role of the Nowa protein family members during genome rearrangement in Paramecium tetraurelia

69

Behera, Alok Small molecule inhibitors of LIN28 to restore miRNA biogenesis 70

Beneventi, Giulia Dynamic spliceosomal RNA modification directs mRNA splicing during oncogenic stress

71

Benoni, Roberto Optimization of LC/MS method for the identification of RNA modification 72

Bernier, Annie miR-122 protects the 5' end of the Hepatitis C Virus RNA genome from cellular pyrophosphatases

73

Page 18

Posters A-Z

Bertrams, Wilhelm Non-coding RNAs in proinflammatory macrophage activation 74

Béthune, Julien L. Dual mode of mRNA silencing by the RNA-binding protein GIGYF2 75

Bielli, Pamela c-MYC regulates transcription and productive splicing of the oncogenicsplicing factor Sam68 in cancer

76

Bilodeau, Danielle Y. Open reading frames are a key mediator of mRNA stability in the protist Giardia lamblia

77

Bisaria, Namita miRNA 3'-supplemental and compensatory pairing affinity is determined by base-pairing thermodynamics, loop entropy, and seed-pairing state

78

Biswas, Jeetayu The structural basis for RNA selectivity by the IMP family of RNA binding proteins

79

Blasco-Moreno, Bernat Presenter: Díez, Juana Xrn1 links mRNA synthesis, translation and decay 80

Boccaccio, Graciela Dusp11 regulates non-coding RNAs during the stress response 81

Böhm, Volker Exon junction complexes suppress spurious splice sites to safeguard transcriptome integrity

82

Boileau, Etienne Landscape of RNA translation in the mouse heart 83

Boros, Éva Interdependent gene- and microRNA-expression pattern contributes to the epithelial to mesenchymal transition in Inflammatory Bowel Disease

84

Page 19

EMBO|EMBL Symposium: The Complex Life of RNA

Bresson, Stefan Stress-induced changes to the RNA binding proteome in yeast 85

Britto-Borges, Thiago Carina: Web Application for Tissue-Specific Gene Regulation Applied to Cardiovascular Disease Models

86

Büscher, Magdalena “High VaultAge” – Molecular studies on the vault RNA1-1 – p62 interaction

87

Cahova, Hana LC/MS analysis of viral RNA packageome 88

Casañal, Ana A Hub for 3’-end Processing: Structural Insights into mRNA Polyadenylation

89

Cassella, Lucia Global analysis of RNA localisation in follicular epithelial cells under different nutritional conditions

90

Castelo-Szekely, Violeta Translatome-wide, DENR-regulated reinitiation events uncover predictive uORF features and links to circadian timekeeping via Clock regulation

91

Cerda-Jara, Cledi Characterizing the expression of the circRNA Cdr1as and its regulatory network in mouse primary neurons

92

Christoffel, Gabriele Presenter: Widmann, Philipp Comparison of different methods for miRNA purifcation from plasma 93

Chu, Chia-Chieh (Jack) HIV-1 RRE stem IIB adopts two inactive conformational states that prevent Rev binding

94

Chuang, Tzu-Wei The Role of the RNA Processing Factor Y14 in DNA Repair 95

Page 20

Posters A-Z

Chworos, Arkadiusz Gene expression control using multivalent RNA nanoparticles 96

Conn, Simon Don't go in circles: Circular RNAs as confounding factors in gene expression

97

Cornet, David Alternative splicing patterns in the transcriptome of mature human oocytes

98

Cortés López, Mariela The patterns of Alu exonisation in human cancer 99

Creugny, Antoine Identification of factors regulating virus-encoded microRNA biogenesis 100

Croce, Stefano Presenter: Staehler, Peer Novel bioconjugation system for mRNA therapy 101

Cvackova, Zuzana Retinitis pigmentosa linked mutation of Prpf8 102

Dalmia, Anupriya Systematic Functional Characterization of Long Non-Coding RNAs Expressed in the Human Brain

103

Damodaran, Arun Prasath The role of Aurora-A in pre-mRNA splicing 104

Darivcak, Peter Localization and translation of stored mRNA in pollen grains and pollen tubes

105

Das, Megha Continuous light, an ultimate artificial light pollution affects pregnancy by disrupting Bmal, Clock, Period & Cryptochrome gene expression in mice uterus

106

Page 21

EMBO|EMBL Symposium: The Complex Life of RNA

De Paolis, Veronica Post-transcriptional regulation of the pan-neurotrophin receptor p75 during neuronal differentiation

107

Depaix, Anaïs Synthesis of NAD analogs to study NAD-linked RNA decapping enzymes 108

Dezi, Veronica Dissecting the spatiotemporal mechanisms underlying localised protein synthesis

109

Dhingra, Priyanka Presenter: Munch, Robin Screening of RNA Binding Proteins Driving Bainbridge-Ropers Syndrome 110

Di Liddo, Antonella CircRNome profiling in cancer cells upon hypoxic stress 111

Regulation of spatial and temporal gene expression in an animal germline 112

Dimitrova-Paternoga, Lyudmila Structural and functional analysis of novel RNA binding proteins involved in Drosophila RNA transport and cytoskeletal organisation

113

Dobrev, Nikolay Structural and functional insights of MTREC core complex 114

Dold, Annabelle Makorin 1 is required for translation of oskar mRNA during Drosophila oogenesis

115

Dou, Yuhui Investigating Novel Functions of Human Nuclear Cap Binding Proteins 116

Downes, Nicholas Transcriptional regulation of HIF1a by novel hypoxia-inducible lncRNA 117

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Presenter: Diag, Asija; Schilling, Marcel Diag, Asija

Posters A-Z

Drexler, Heather Long-read NET-seq reveals the kinetics of metazoan co-transcriptional splicing

118

Dubois, Josephine New Circular RNAs of the human TRAM1 System 119

Dumont, Audrey-Ann Cardiomyocyte regulation of SRSF3-dependent alternative splicing by p38a MAPK

120

Eberle, Andrea B UPF1 in the cell nucleus 121

Eberth, Sonja MicroRNA Signatures from Cytoplasmic and Nuclear Compartments in B cell Non-Hodgkin Lymphoma

122

Egler, Franziska Role of the eIF4E1-4EIP complex in gene repression during differentiation of trypanosomes

123

Erben, Esteban Identification and function of the VSG transcript-bound proteome: methodological development and preliminary findings

124

Erni, Andrea Unravelling the direct role of miRNAs during neurogenesis by identifying functional miRNA/mRNA complexes in the mouse brain

125

Fernandes, Ana Miguel Exploring RNA polymerase II regulation in the biogenesis of circular RNAs

126

Fernandes, Rayzel C. A miR-194-regulated transcriptional network promotes progression to neuroendocrine prostate cancer

127

Presenter: Ehses, Janina; Fernández Moya, Sandra M.

Staufen 2 regulation of mRNA targets in mature neurons 128

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Fernández Moya, Sandra M.

EMBO|EMBL Symposium: The Complex Life of RNA

Fernández-Miranda, Gonzalo CPEB1 and CPEB4 play opposite functions in epidermal homeostasis and tumorigenesis by coordinating metabolic reprogramming

129

Filippova, Iuliia Functional study of snoRNA activity in human cells using CRISPR/Cas9 genome editing systems

130

Florini, Francesca RHS proteins: a novel multiprotein family involved in transcriptional elongation of Trypanosoma brucei

131

Friebe Sandoz, Sarah Tackling RNA in-cell NMR with a miRNA model system 132

Fromont-Racine, Micheline Presenter: Jacquier, Alain

A SKI subcomplex is specifically required for the degradation of ribosome-free RNA regions

133

Fuchs, Anna-Lisa A general method for rapid and cost-efficient large-scale production of 5' capped RNA

134

Fuchs, Steffen Circular RNAs contribute to the pathogenesis of neuroblastoma 135

Fuentes-Iglesias, Alejandro ADAR1 catalytic activity is required for efficient somatic cell reprogramming in a stage-dependent manner

136

Furlong, Fiona Evaluation of the posttranscriptional modificaiton of microRNA 137

Gaete Argel, Aracelly Effect of HIV-1 expression on the Deccaping machinery associated to Processing Bodies

138

Ganser, Laura Targeting an alternate conformational state of HIV-1 TAR RNA 139

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Posters A-Z

140

141

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146

147

148

Gasiule, Stase Role of miRNAs in development of ascending thoracic aneurysm

Gasperini, Caterina Identification of piRNAs and functional investigation of piRNA-pathway in adult mammalian Neural Progenitor Cells

Gatfield, David Genome-wide translational pausing events and their functional implications revealed from the sequencing of disome footprints

Gathmann, Stephanie The ribonucleoprotein CP29A forms cold-responsive granular structures in Arabidopsis chloroplasts

Gatsiou, Aikaterini The RNA editor, ADAR2, is required for leukocyte trafficking to inflamed tissues

Gaysinskaya, Valeriya Insights into telomerase RNA biogenesis and processing from short telomere patients

Gerber, André P. Profiling the cisplatin induced rearrangement of RNA-binding proteins on CDKN1B/p27 mRNAs identifies potential modulators of drug sensitivity

Ghidini, Alice Inhibition of Lin28/pre-let-7 binding through short oligonucleotides

Girardi, Erika Neuron-specific miR-124 positively regulates Sindbis virus infection

Gonatopoulos-Pournatzis, Thomas A brain-specific exon in eIF4G controls synaptic translation and higher-order cognitive functions

Genome-wide CRISPR-Cas9 interrogation of splicing networks reveals a mechanism for recognition of autism-misregulated neuronal microexons

149

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Goos, Carina Presenter: Kramer, Susanne Trypanosomes can initiate nuclear export co-transcriptionally 150

EMBO|EMBL Symposium: The Complex Life of RNA

Gowravaram, Manjeera Molecular mechanisms of Staufen-mediated mRNA decay pathway 151

Graczyk, Anna StRNA – Spherical tecto-RNA (StRNA) - a fresh wave in the Spherical Nucleic Acids’ science

152

Graille, Marc Recruitment of the mRNA decay machineries to the 5’ end of mRNAs 153

Gray, Nicola K. Unexpected importance of PABP4 in mammalian pregnancy: A unique mouse model for the maternal origins of IUGR and stillbirth

154

Gregersen, Lea H. SCAF4 and SCAF8 are essential transcriptional termination regulators in human cells

155

Gressel, Saskia B. Regulatory strategies of transcriptional reprogramming in human cells 156

Griesbach, Esther H2A.X polyA- and polyA+ mRNAs are differentially regulated during the cell cycle and the polyA+ mRNA is required under DNA damage conditions

157

Grima, Brigitte POP2-dependent mRNA deadenylation controls TIMELESS oscillations in Drosophila

158

Grosch, Markus Paraspeckles regulate multipotent neural progenitors via activin/nodal pathway

159

Grosshans, Helge Presenter: Liu, Jun Molecular and developmental functions of mRNA silencing by LIN41 160

Guimaraes, Joao A rare codon-based translational program drives cell proliferation 161

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Posters A-Z

Haimovich, Gal Intercellular mRNA trafficking via membrane nanotubes: scope, mechanism and cellular effect.

162

Hämmerle, Monika Differential expression and subtype-specific function of lncRNAs in pancreatic adenocarcinoma

163

Hanswillemenke, Alfred Light-controlled targeting of cellular RNAs using engineered artificial riboproteins

164

Hardwick, Simon Transcriptional complexity of non-coding genomic regions associated with cognitive function

165

Hassan, Nunki MicroRNA-497 acts as a tumour suppressor by regulation of long noncoding RNA MALAT1 in adrenocortical carcinoma

166

Heber, Simone The role of Staufen 2 RNA-binding domains 1 and 2 in RNA recognition 167

Higdon, Andrea Meiotic production of N-terminally truncated proteins in S. cerevisiae 168

Hisaoka, Miharu Alteration of translational regulation in colorectal cancer 169

Höfer, Katharina Bacterial RNA Gets an NAD-Cap – But How to Remove it? 170

Hoffman, Alyson Domain Organization of Translation on the Endoplasmic Reticulum Revealed by Proximity Interactome Analysis

171

Hoffmann, Tobias What and How: Insights from cancer mutations into RBM10's function 172

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EMBO|EMBL Symposium: The Complex Life of RNA

Hofmann, Katharina Identification of 3-methylcytidine in tRNA Arginine of S. cerevisiae 173

Holetz, Fabíola The mRNA cycle in Trypanosoma cruzi 174

Horn, Andreas Characterization of the translational nanos repression in early fly oogenesis

175

Horvath, Anelia Genome-wide trans-effects of RNA-editing across 26 human tissues 176

Hudecek, Oldrich Cytidine methylation in viral RNA 177

Huppertz, Ina Regulation of enolase 1 enzyme activity by RNA 178

Ibrahim, Amr Detect Alternative Transcription start sites and 5'UTR in Halobacterium salinarum NRC-1 and their responsibility in gene regulation

179

Ibrahim, Fadia Ribothrypsis, a novel process of mRNA decay and beyond 180

Jacob, Dominik Quantification of diverse RNA species using Microscale Thermophoresis 181

Jacob, Roland Molecular analysis of Dicer-deficient cells suggests alternative miRNA processing pathways

182

Jakobi, Tobias circtools — a one-stop software solution for circular RNA research 183

Janoušková, Martina Synthesis and Degradation of Ms1 in Mycobacterium smegmatis 184

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Posters A-Z

Jansova, Denisa Spatio temporal mRNA translation in mitosis 185

Jens, Marvin Reconstructing physical properties of RNA-protein interactions from RNA Bind'n'Seq experiments

186

Johnson, Alex Stability and instability of the human translation initiation particle 187

Kafasla, Yiota Interactions between nuclear RNPs and scaffold proteins determine Alternative splicing pattern changes in cancer.

188

Kanwal, Nidhi Identification of new mitochondrial membrane proteome by mRNA proximity ligation

189

Kao, Shao-Yen Scaf6 (DmCHERP) regulates alternative splicing during development of Drosophila flight muscle

190

Katsioudi, Georgia Investigating the role of NMD in circadian gene expression using a novel genetic Smg6 loss-of-function model

191

Khan, Shazia Deep sequencing of Artemisia annua L. plant small RNAs identifies miRNAs involved in the specialized metabolite production

192

Kisly, Ivan The functional importance of ribosomal eukaryote-specific intersubunit bridges eB12 and eB13 for the mRNA translation

193

König, Julian hnRNPH controls the cis regulatory landscape of RON alternative splicing

194

Krasny, Libor The Torpedo Effect in Bacillus subtilis: RNase J1 Resolves Stalled Transcription Complexes

195

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EMBO|EMBL Symposium: The Complex Life of RNA

Kretschmer, Jens he m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5'-3' exoribonuclease XRN1

196

Kute, Preeti M. NMDAR mediated translation at the synapse is regulated by MOV10 and FMRP

197

Lafarga, Vanesa Inhibition of translation by C9ORF72-associated dipeptides as a therapeutic target in ALS disease.

198

Lang, Benjamin RNAct: Protein–RNA interaction predictions for model organisms with supporting experimental data

199

Lapinski, Maciej Efficient crRNA design and targeted RNA knockdown with Type III-A CRISPR-Cas system in zebrafish

200

Lavysh, Daria On the way to deciphering the mRNP at prematurely terminating ribosomes

201

Laxa, Miriam Intron-mediated enhancement on translational level 202

Lebedeva, Svetlana Long non-coding RNAs in neuronal differentiation 203

Lebreton, Alice Balance between transcriptional and translational regulation in human cells infected by Listeria monocytogenes

204

Lee, Mihwa Crystal Structures of DBHS family proteins: Towards Structural Insights into RNP granule formation and Gene Regulation

205

Legnini, Ivano Sequencing human mRNAs from head to toe 206

Page 30

Posters A-Z

Leng, Xueyuan The Role of Transcription Kinetics in Plants 207

Leung, Sara W. Functional Consequences of Disease-linked Amino Acid Substitutions within the RNA Exosome Complex

208

Lewis, Natasha Role of RNA in regulating spatiotemporal dynamics of biomolecular condensates

209

Lirussi, Lisa Presenter: Nilsen, Hilde SMUG1 promotes telomere maintenance through telomerase RNA end-processing

210

Lirussi, Lisa The human DNA repair protein SMUG1 in ribosomal RNA metabolism 211

Liu, Bin The stimulatory zinc finger protein ZC3H20 targets mRNAs encoding developmentally-regulated mitochondrial and membrane proteins

212

Lu, Chia-Chen The role of Y14 in DNA damage response 213

Luís, Rui Promoter-proximal convergent antisense transcripts (PCATs): a novel class of regulatory non-coding RNAs

214

Lukarska, Maria Structural Studies on the Interaction between Influenza Polymerase and RNA Polymerase II

215

Lukavsky, Peter J. Staufen1 reads out structure and sequence features in ARF1 SBS for specific target recognition

216

Lukoszek, Radoslaw mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription

217

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EMBO|EMBL Symposium: The Complex Life of RNA

Maguire, Eithne Linc1290: Novel player in vascular stem cell differentiation 218

Makarov, Evgeny Regulation of the LMNA pre-mRNA splicing associated with ageing 219

Manhart, Linda Axonal translation of the presynaptic protein Bruchpilot is dispensable for adequate protein localization, but likely facilitates synaptic homeostasis

220

Mariani, Davide A long non coding RNA interacts with G-quadruplex containing mRNAs and represses DHX36-dependent translation

221

Marini, Alberto TAp73 contributes to the oxidative stress response by regulating protein synthesis

222

Maulik, Aditi The sequence structure and evolutionary features of lincRNA-p21 with implication in function

223

Mehta, Dolly RNA-mediated post-transcriptional gene regulation in Mycobacteria 224

Metheetrairut, Chanatip Expression Levels of miR-34-family microRNAs are Associated with TP53 Mutation Status in Head and Neck Squamous Cell Carcinoma

225

Milev, Nikolay The Role of Upstream Open Reading Frames in the regulation of the circadian Cryptochrome 1 gene

226

Miscicka, Anna Non-AUG translation generates new protein isoforms with mitochondrial localization

227

Mizrahi, Orel Virus-induced changes in mRNA secondary structure uncover cis-regulatory elements that directly control gene expression

228

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Posters A-Z

Mo, Dingding The role of Aß circRNA in Alzheimer’s disease: alternative mechanism of Aß biogenesis from Aß circRNA translation

229

Mohana Sundara Shanmugam, Giriram The Drosophila 7SK snRNP complex is specifically required for synaptic

growth and function of motoneurons. 230

Montiel-Duarte, Cristina Transcription Start Site selection and its impact on protein expression 231

Morales, Julia Translatome analysis at the egg-to-embryo transition in sea urchin 232

Mordstein, Christine Position- and splicing-dependent effects of codon usage in human cells 233

Mordue, Ryan OTUD4: an RNA binding deubiquitinase 234

Mori, Ryoichi Comprehensive identification of wound healing and inflammation miRNAs reveals a key role for miR-223 in neutrophilic clearance of S. aureus at wound sites

235

Moskovtsev, Alexey Presenter: Zaichenko, Danila; Moskovtsev, Alexey

Small RNA processing during endoplasmic reticulum stress: looking for a new sense of RNA pieces

236

Mugat, Bruno Presenter: Basyuk, Eugenia The NuRD complex mediates piRNA-induced heterochromatin formation in metazoans

237

Mugridge, Jeffrey Multimodal activation of decapping during 5’-3’ mRNA decay 238

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EMBO|EMBL Symposium: The Complex Life of RNA

Müller-McNicoll, Michaela Presenter: McNicoll, Francois Regulation of SRSF7 involves unproductive splicing, 3’UTR extension, translation of truncated isoforms and nuclear retained mega RNPs

239

Munschauer, Mathias The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

240

Naarmann-de Vries, Isabel S. Analysis of differential mRNA-protein interactions implicated in the hypoxic response

241

Neelagandan, Nagammal TDP-43 modulates translation of specific mRNAs linked to neurodegenerative disease

242

Nicassio, Francesco Target-directed miRNA degradation in mammalian cells 243

Nikulin, Alexey D. Can archaeal Lsm proteins interact with RNA in the same manner as their bacterial homologue?

244

Nojima, Takayuki Deregulated expression of lncRNA induces R-loop formation, replication stress and cellular senescence

245

Obuca, Mina A missense mutation in DDX38 that causes retinitis pigmentosa 246

Osman, Ismail A sisRNA/miRNA axis prevents loss of germline stem cells during starvation in Drosophila

247

Ostareck, Dirk H. Interaction of hnRNP K and rpS19 and its function in erythroid maturation

248

Ostareck-Lederer, Antje P23 acts as functional RBP in macrophage inflammation response 249

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Posters A-Z

Ostrakova, Jitka Presenter: Ostrakova, Jitka; Watanabe, Kenji

RNA polymerase suppression by a CDK7/12/13 inhibitor as a promising therapeutic strategy to target Ewing sarcoma

250

Ouellet, Jimmy A novel single molecule platform that allows splice variant analysis, sequencing and the detection of epigenetic modifications of native RNA molecules

251

Ouyang, John Paul Maintaining Small RNA Homeostasis via Two Intrinsically Disordered Germ Granule Proteins in Caenorhabditis elegans

252

Pagano, Johanna Alternative rRNA in zebrafish development 253

Pandey, Deo Epitranscriptomic regulation in Glioblastoma 254

Parab, Sushant Control of Endothelial cells phenotypic switch by ncRNAs 255

Patutina, Olga miRNA-targeted artificial ribonucleases – miRNases – efficiently inactivate miRNAs in tumour cells acting synergistically with RNase H in multi-turnover mode

256

Pereira Montecinos, Camila The presence of m6A within the 5´UTR of the HIV-1 genomic RNA defines its usage as mRNA or as the packaged genome

257

Perez-Perri, Joel I. Discovery of RNA-binding proteins and characterization of their dynamic biological responses by enhanced RNA interactome capture

258

Persson, Helena MicroRNA-convergent gene fusions in cancer 259

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EMBO|EMBL Symposium: The Complex Life of RNA

Pinheiro, Helena Linking mRNA degradation with mRNA localization in skeletal muscle cells

260

Plass, Mireya Alternative polyadenylation survey in single cells identifies 3’UTR changes regulating gene expression during cell cycle progression

261

Poddar, Anustup Investigation of sequence-dependent bacterial small RNA function using SortSeq and super-resolution imaging

262

Pons Espinal, Meritxell

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MiR-135a-5p is critical for exercise-induced proliferation of adult neurogenesis

Popovic, Branka Posttranscriptional regulation of cytokine production in T cells by RNA binding proteins

Powers, Emily Translation control during meiosis in budding yeast

Prudêncio, Pedro Genome-wide analysis of the nascent RNApolII transcriptome during Drosophila development.

Puhakka, Noora Altered small RNA signature in the ipsilateral thalamus and perilesional cortex of rats with chronic neuroinflammation after experimental traumatic brain injury

Queiroz, Rayner OOPS: a low-cost simple method to enrich RNA binding proteins and identify their sites of RNA interaction

Rajyaguru, Purusharth Self-association regulates repression activity of RGG-motif proteins

Joyita, Mukherjee mRNA interactome analysis by RNA-BioID 270

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Presenter: De Pietri Tonelli, Davide

Posters A-Z

Ramos-Alonso, Lucía The yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

271

Rayner, Simon Presenter: Liu, Siqing Targeting differences: Contrasts between canonical and non-canonical target sites using miRAW

272

Razew, Michal Structure and function of the mitochondrial RNA degradosome mtEXO 273

Reyes-Gutierrez, Paul E. Presenter: Hudecek, Oldrich Development of capturing technique for 5’-diphosphate RNA 274

Riquelme-Barrios, Sebastian Role of cytoplasmic N6-methyladenosine (m6A) readers on HIV-2 protein synthesis

275

Roithová, Adriana Quality control of snRNP assembly 276

Rolando, Chiara Post-transcriptional regulation of metabolic functions in astrocytes during brain ageing

277

Routh, Satya Brata Mechanistic and functional studies of chiral proofreading during translation of the genetic code

278

Ruijtenberg, Suzan A role for ribosomes in small RNA mediated mRNA cleavage 279

Saini, Harleen Free circularized introns with unusual branchpoints in neuronal projections

280

Sajjanar, Basavaraj Role of RNA modifications in virus-host interactions 281

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EMBO|EMBL Symposium: The Complex Life of RNA

Sakamura, Yurika Molecular mechanism underlying deadenylation by which trans-acting factors such as miRISCs and RNA-binding proteins regulate mRNA stability

282

Salehi, Saeede The Impact of Overexpression of HI-LNC25 on Differentiation of Wharton’s jelly-Derived Mesenchymal Stem Cells into Insulin Producing Cells

283

Sanchez, Ferran Analyzing cis elements in DOG1 antisense promoter 284

Sathe, Ameya Deciphering the role of long non-coding RNA DANCR in DNA methylation

285

Schiaffini, Marlene Functional study of UCN a novel P-body component in Arabidopsis thaliana

286

Schlösser, Amelie U1snRNP inhibits 3' end processing by modulating the C-terminal domain of RNA polymerase II

287

Schmid, Manfred A New Method to Interrogate Gene Expression Reveals the Importance of Nuclear RNA Hygiene in Yeast

288

Schulz, Laura CD19 alternative splicing in B cell acute lymphoblastic leukemia during CART-19 immunotherapy relapse

289

Schwich, Oliver Daniel SRSF3 and SRSF7 regulate alternative polyadenylation (APA) through a competition for the activation of proximal poly(A) sites

290

Scoyni, Flavia The role of non-coding RNA network in regulating cellular functions in cerebral ischemia

291

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Posters A-Z

Seal, Ruth genenames.org: the HGNC nomenclature resource for human non-coding RNA genes

292

Selvasaravanan, Karthika Devi Modulating signaling pathways by SNAP-ADAR mediated RNA editing 293

Sendoel, Ataman Reprogramming the Translational Landscape in Tumorigenesis 294

Shender, Victoria The role of exogenous spliceosomal snRNAs in communication between cancer cells

295

Shilo, Asaf RNA structure-function analysis reveals interplay of primary sequence and secondary structure in determining 5’ splice site choice

296

Sikorski, Pawel J. Ligand-functionalized 5’cap mRNA analog as new in-cell translation inhibitors

297

Sinkunas, Tomas 298

Smith, Tom OOPS enables the characterisation of RNA-protein interaction dynamics in any organism

299

Smolik, Ondrej A functional analysis of localization elements in maternal transcripts 300

Sohrabi-Jahromi, Salma Presenter: Sohrabi-Jahromi, Salma; Hofmann, Katharina

Transcriptome maps of the general RNA degradation machinery 301

Stafforst, Thorsten SNAP-tagged Tools to Manipulate the Transcriptome 302

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Influence of crRNA length for DNA interference in a CRISPR-Cas system

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EMBO|EMBL Symposium: The Complex Life of RNA

Stepanov, Grigory Effects of nucleotide modifications on the properties of snoRNA analogues

Stoffel, Nina Kim The mitochondrial memRBP Clu1 - investigating the link between endosomal mRNA transport and mitochondrial biogenesis

Sugunan, Sreedevi profiling mRNA localization on the surface of mitochondria during zebrafish development

Sun, Mai Investigation of the FK506-binding protein Fpr1 as an enigmRBP

Svojanovska, Barbora NAD-RNA in viral infected cells

Tang, Terence Specificity of Deadenylation is Determined by Poly(A) Stacking

Tavukcuoglu, Zeynep The existence of exosomal mirnas in the circulation in familial mediterranean fever (FMF) patients

Tebaldi, Toma Transcriptome-wide impact of U2AF1 mutations on RNA binding, splicing and translation in myelodysplastic syndromes

Teixeira da Rocha, Simão Genetic dissection of Xist lncRNA reveals independent RNA modules involved in transcriptional silencing and heterochromatin formation

Thonta Setty, Samarth High-throughput screening reveals extensive regulation of RON alternative splicing by the RNA-binding protein hnRNP H

Thran, Moritz mRNA as a medical agent: From bench to (pre-)clinics 313

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Posters A-Z

Tippmann, Frank Impact of translation speed on co-translational protein folding and chaperone recruitment

314

Trendel, Jakob Exploring Global Protein-RNA Interactions Using XRNAX 315

Tulinski, Markus Identification of Rrm4-associated factors involved in endosomal mRNA transport

316

Tutucci, Evelina An Improved MS2-MCP system to follow single cell cycle mRNAs from transcription to degradation in S. cerevisiae

317

Uebersohn, Alec Identification and characterization of N-terminally truncated proteins in budding yeast meiosis

318

Ulrychová, Lenka Novel transcripts of serine proteases detected in pathogenic helminth Schistosoma mansoni by improved in situ hybridization technique

319

Umehara, Takahiro Identification of specific microRNA in diabetic-derived neutrophils: functional analysis of miR-129-2-3p in inflammation-related genes

320

Urim, Shira "mRNA imprinting": Regulation of Gene Expression by Co-transcriptionally Associating Proteins

321

Vabulas, Martin TRMT6/61A Methyltransferase Safeguards mRNAs during Proteostasis Stress and Amyloidogenesis

322

Vagner, Stephan The eIF4F Translation Complex Controls T lymphocyte-Induced PD-L1 Expression to Mediate Tumor Immune Escape

323

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EMBO|EMBL Symposium: The Complex Life of RNA

Valentine, Matthew Exploring transcriptomic space in the search for PD diagnostic biomarkers

324

Vance, Keith W. The long non-coding RNA DIRC3 is a new melanoma tumour suppressor gene

325

Vancura, Adrienne Evidence for deeply-conserved cancer-driving roles of long non-coding RNAs

326

Vangoor, Vamshidhar R Unravelling the function of Nuclear localized miRNAs in Temporal Lobe Epilepsy

327

Vasiljevic, Jovana hnRNP A2/B1 as a novel post-transcriptional regulator of insulin expression in ß-cells

328

Vlachogiannis, Nikolaos Intronic adenosine-to-inosine RNA editing controls cathepsin K expression in inflammatory diseases by coupling pre-mRNA processing with mRNA stability

329

Voigt, Franka Quantifying gene expression noise via single mRNA imaging in living cells 330

Voineagu, Irina Presenter: Gokoolparsadh, Akira The Landscape of Circular RNA Expression In The Human Brain 331

Voineagu, Irina Presenter: Green, Nicole Regulation of eRNA expression and long gene transcription by Topoisomerase I

332

Wakai, Michihito Presenter: Stoecklin, Georg Acetylation-Dependent Control of Global Poly(A) RNA Degradation 333

Waldron, Joseph Global mRNA Structure-Seq yields insights into the helicase activity of eIF4A during translation initiation

334

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Posters A-Z

Wallace, Edward Start codon context plays a major role in proteome regulation, diversity, and localization in fungi

335

Warkocki, Zbigniew Uridylation by TUT4/7 restricts retrotransposition of human LINE-1s 336

Werner, Stephan Reverse Transcriptase combinations in RNA-Seq: Transcriptome-wide mapping of N1-methyladenosine (m1A) at single-nucleotide resolution

337

Wery, Maxime Bases of antisense lncRNA-associated regulation of gene expression in fission yeast

338

Whisnant, Adam Comprehensive Reannotation of the Herpesviral Transcriptome and Translatome

339

Wippich, Frank Deciphering the dynamic mRNP composition and regulatory principles of locally translated mRNAs in Drosophila oogenesis

340

Witzenberger, Monika Is the tRNA methyltransferase TRMT2a a novel drug target for treatment of Huntington’s disease?

341

Wolczyk, Magdalena Response of FXR1P and FXR2P proteins to hypoxia in leukemia cells 342

Wu, Mengjun Degradation of RNA transcribed from protein-coding genes by exosome 343

Wu, Pei-Chi MicroRNAs derived from the insect virus HzNV-1 promote lytic infection by suppressing histone methylation

344

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EMBO|EMBL Symposium: The Complex Life of RNA

Wu, Ruifan FTO regulates adipogenesis by controlling cell cycle progression via m6A-YTHDF2 dependent mechanism

345

Yang, Siwy Ling Discovery of a novel cysteine riboswitch in eukaryote 346

Yanovsky, Marcelo Spliceosome assembly factors are only essential for survival under stress conditions in plants

347

Yu, Jiancheng Presenter: Hui, Jingyi RNA binding protein QKI mediates a positive feedback loop of Wnt signaling in lung cancer

348

Zander, Sindy Characterization of RBM47 and its role in OSCC metastasis 349

Zaremba, Mindaugas Specificity of the Argonaute protein from Archaeoglobus fulgidus to the 5‘-end of the guide

350

Zarnack, Kathi The key protein of endosomal mRNP transport binds translational landmark sites of cargo mRNAs

351

Zarnack, Kathi Presenter: Brüggemann, Mirko The RNA binding profile of the E3 ubiquitin ligase MKRN1 352

Zhao, Qian A novel tumor related gene, HPO-11/NRBP affects mRNA fate in C. elegans

353

Zhuravlev, Evgenii Nucleotide modifications is a way to regulate activities of Cas9/sgRNA complexes

354

Zuber, Hélène Respective roles of URT1 and HESO1 in the uridylation of RISC-cleaved transcripts

355

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Posters A-Z

Zuo, Zhangli Presenter: Zuo, Zhangli; Petersen, Morten

Arabidopsis PAT mRNA decay factors funcions in hormonal responses and apical hook development

356

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Aindrila Chatterjee

Exploring the role of RNAs in mitochondrial respiration 357

Nuno Saraiva-Agostinho

Psichomics: a bioinformatics application for the quantification, analysis and visualisation of alternative splicing from large transcriptomic datasets

358