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MedDRA LLT Abbreviations / Acronyms 08/21/2013 Page 1 of 20 MedDRA LLT (current LLTs only) ABO ABO isoimmunization ACE ACE inhibitor foetopathy ACTH ACTH stimulation test normal ADA ADA deficiency ADD ADD ADH ADH normal ADMA ADMA abnormal AFP AFP result - normal AG AG ratio abnormal AIDS AIDS retinopatHy Alk phos Alk phos raised ALK ALK receptor tyrosine kinase assay ALK-NPM ALK-NPM gene fusion assay ALP ALP increased ALT ALT increased ANA ANA present ANCA ANCA positive ANNA ANNA-1; ANNA-2 ANP ANP APACHE II APACHE II score increased APGAR Apgar score normal aPTT APTT prolonged ARC ARC ARIA ARIA; ARIA-E; ARIA-H ASO ASO titre AST AST increased ATRA ATRA syndrome BCL-2 BCL-2 gene status assay Abbreviation / Acronym

Abbreviations Acronyms 08-21-2013

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MedDRA Term abbrv_acronym listAbbreviation / AcronymMedDRA LLT (current LLTs only) MeaningABOABO isoimmunizationLandsteiner's blood grouping systemACEACE inhibitor foetopathyAngiotensin-converting enzymeACTHACTH stimulation test normalAdrenocorticotropic hormoneADAADA deficiencyAdenosine deaminaseADDADDAttention deficit disorderADHADH normalAntidiuretic hormoneADMAADMA abnormalAsymmetric di-methylarginineAFPAFP result - normalAlpha-fetoproteinAGAG ratio abnormalAlbumin - GlobulinAIDSAIDS retinopatHyAcquired immune deficiency syndromeAlk phosAlk phos raisedAlkaline phosphatase(sometimes abbreviated as ALP)ALKALK receptor tyrosine kinase assayAnaplastic lymphoma receptor tyrosine kinaseALK-NPMALK-NPM gene fusion assayAnaplastic lymphoma kinase and nucleophosminALPALP increasedAlkaline phosphatase(sometimes abbreviated as Alk phos)ALTALT increasedAlanine transaminaseANAANA presentAntinuclear antibodyANCAANCA positiveAntineutrophil cytoplasmic antibodyANNAANNA-1; ANNA-2Anti-neuronal nuclear antibodyANPANPAtrial natriuretic peptideAPACHE IIAPACHE II score increasedAcute Physiology and Chronic Health Evaluation IIAPGARApgar score normalAppearance, pulse, grimace, activity, respiration- used to assess newbornsaPTTAPTT prolongedActivated partial thromboplastin timeARCARCAIDS related complexARIAARIA; ARIA-E; ARIA-HAmyloid related imaging abnormality (where appended E stands for edema and H stands for microhaemorrhage and haemosiderin deposits)ASOASO titreAntistreptolysin-OASTAST increasedAspartate transaminaseATRAATRA syndromeAll-trans retinoic acidBCL-2BCL-2 gene status assayB-cell lymphoma 2BCCBCC excisionBasal cell carcinomaBCGBCG related lymphadenitisBacille Calmette-Guerin(atuberculosisvaccination)BGPBGPOsteocalcin (bone Gla-protein bone marker)BNPBNP normalBrain natriuretic peptideBPBP raisedBlood pressureBPSDBPSDBehavioural and psychiatric symptoms of dementiaBrBrBromideBRCABRCA1 gene mutationBreast cancer gene 1BSPBSP excretion delayedBromsulphthaleinBUNBUN normalBlood urea nitrogenC1C1 inhibitor functional assayComplement factor C1CACa phobiaCarcinomaCANDLECANDLE syndromeChronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature syndromeCATCATComputed axial tomographyCBCCBC normalComplete blood countCEACEA antigen increasedCarcinoembryonic antigenCHARGECHARGE syndromeColoboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth and/or development, Genital and/or urinary abnormalities, and Ear abnormalities and deafness.CICI increasedCardiac indexCIDPChronic inflammatory demyelinating polyradiculoneuropathyChronic inflammatory demyelinating polyradiculoneuropathyCISCIS of cervixCarcinoma in situCKCK normalCreatine kinaseClClChlorideCLLCLL variantsChronic lymphocytic leukemiaCMLCML progressionChronic myelogenous leukemia, also called chronic myeloid leukaemiaCMVCMV viremiaCytomegalovirusCNSCNS ventriculitis, CNS toxicityCentral nervous systemCO2CO2 total abnormal NOSCarbon dioxideCOPDCOPD exacerbationChronic obstructive pulmonary diseaseCPAPNasal CPAPContinuous positive airway pressureCPKCPK normalCreatine phosphokinaseCRESTCREST syndromeCalcinosis, Raynaud esophagus, sclerosis, teleangiectasiaCRMOCRMOChronic recurrent multifocal osteomyelitisCRPCRP positiveC-reactive proteinCSFCSF white cell count NOS normalCerebrospinal fluidCTCT urographyComputed tomographyCuCuCopperCVPCVP normalCentral venous pressureCXRCXR normalChest x-rayCYPCYP2C19 intermediate metaboliser statusCytochrome P450DEXADEXA scanDual energy X-ray absorptiometryDILIDrug-induced liver injuryDrug induced liver injuryDNADNA test for fragile XDeoxyribonucleic acidDRESSDRESS syndromeDrug reaction with eosinophilia and systemic symptomsDUBleeding DUBleeding duodenal ulcerDVTDVT prophylaxisDeep vein thrombosisEBVEBV viremiaEpstein-Barr virusECGECG signs of ventricular hypertrophyElectrocardiogramECHOEcho virus infection NOSEnteric cytopathic human orphan virusECTECT (electro-convulsive therapy)Electroconvulsive therapyEEGEEG provocation test positiveElectroencephalogramEGFREGFR gene mutationEpidermal growth factor receptorEKGEKG normalElectrocardiogramEMGEMG normalElectromyographyEMGEMGElectromyogramENTENT examination normalEar, nose, and throat (seeotolaryngology)EPCR A3EPCR A3 polymorphismEndothelial protein C receptor ESRESR retardedErythrocyte sedimentation rateFCASFCASFamilial cold autoinflammatory syndromeFeFeIronFGFFGF-23Fibroblast growth factorFISHFISH testFluorescence in situ hybridizationFOB FOB negativeFecal occult blood FRCFRCFRC abnormalFRC decreasedFRC increasedFunctional residual capacityFSHFSH normalFollicle-stimulating hormoneFTAFTA presentFluorescent treponemal antibody (seesyphilis)GADAnti-GAD antibodyGlutamic acid decarboxylaseG-CSFG-CSF therapyGranulocyte colony-stimulating factorGFRGFR raisedGlomerular filtration rateGGTGGT increasedGamma glutamyl transferaseGGTPGGTP increaseGamma glutamyl transpeptidaseGHGH normalGrowth hormoneGIGI upsetGastrointestinal;GIFTGIFTGamete intrafallopian transferGM-CSFGM-CSF therapyGranulocyte macrophage colony-stimulating factorGOTGOT normalGlutamic-oxalacetic transaminaseGPTGPT normalGlutamic-pyruvic transaminaseGTTGTTGlucose tolerance testGVHGVH diseaseGraft-versus-HostH-rasH-ras gene mutationHarvey rat sarcoma oncogeneHbHb decreasedHemoglobinHbA1cHbA1C increasedGlycosylated Hemoglobin(used as a measure ofdiabetescontrol)HBVHBV viral load increasedHepatitis B virusHCVHCV viral load increasedHepatitis C virusHDLHDL raisedHigh-density lipoproteinHELLPHELLP syndromeHaemolysis,elevated liver enzymes, lowplatelets(syndrome) (inpregnancy)HERGHERG gene mutationHuman ether--go-go related geneHibHIB meningitisHaemophilus influenzae BHIVHIV with persistent generalized adenopathyHuman immunodeficiency virusHLAHLA marker tests NOSHuman leukocyte antigenhMPVhMPV testHuman metapneumovirusHOCMHOCM Hypertrophic obstructive cardiomyopathyHypertrophic obstructive cardiomyopathyHRTHRTHormone replacement therapyHSVHSV infectionHerpes simplex virusHTLVHTLV test positiveHuman T-lymphotropic virusIAAnti-IA2 antibody negativeIslet antigenIBDIBDInflammatory bowel diseaseIgIg E increasedImmunoglobulinIgAIgA nephropathyImmunoglobulin AIgDIgD myelomaImmunoglobulin DIgEIgE normalImmunoglobulin EIgGIgG subclass deficiencyImmunoglobulin GIgMIgM increasedImmunoglobulin MINRINR increasedInternational normalized ratIoIOPIOP increasedIntraocular pressureIQIQ test normalIntelligence quotIentIRISIRIS associated Kaposi's sarcomaImmune reconstitution inflammatory syndromeIRVANIRVAN syndromeIdiopathic retinal vasculitis, aneurysms and neuroretinitis syndromeIUCDIUCD expelledIntrauterine contraceptive deviceIVPIVP normalIntravenous pyelogramIVUIVU normalIntravenous urogramJAK-2JAK-2 mutationJanus kinase 2JVPJVP normalJugular venous pressureKKPotassiumK-rasK-ras status assayKirsten rat sarcoma oncogeneKCCTKCCT increasedKaolin cephalin clotting time (seePartial thromboplastin time)KUBKUB X-rayKidneys, ureters, and bladder(x-ray)LabLab test interferenceLaboratoryLADALatent autoimmune diabetes in adultsLatent autoimmune diabetes in adultsLCADLCAD deficiencyLong-chain acyl-coenzyme A dehydrogenase LCHADLCHAD deficiencyLong-chain acyl-coenzyme A dehydrogenase LCMLCM virus infectionLymphocytic meningitisLDHLDH increased urineLactate dehydrogenaseLDLLDL raisedLow-density lipoproteinLELE type reactionLupus erythematosus(in Germanlupus erythematodes)LHLH normalLuteinizing hormoneLPLPLumbar punctureLVLV dyssynchronyLeft ventricleLVFLVFLeft ventricular failureMAPMAP increasedMean arterial pressureMCHMCH normalMean cell hemoglobin;MCVMCV abnormalMean corpuscular volumeMDSMDS transformationMyelodysplastic syndromeMENMEN Type IIMultiple endocrine neoplasiaMgMg reducedMagnesiumMRIMRI normalMagnetic resonance imagingMRSAMRSA wound infectionMethicillin-resistantStaphylococcus aureusMSMS hugMultiple sclerosis(fromLatinsclerosis multiplex)N-rasN-ras status assayNeuroblastoma rat sarcoma oncogeneNaNa increasedSodium(from Latinnatrium)NATNAT2 polymorphismN-acetyltransferaseNKNK cell count increasedNatural killer cellsNMDAAnti-NMDA antibodyAnti-N-methyl-D-aspartate receptor antibodyNT-proBNPNT-proBNP increasedN-terminal prohormone brain natriuretic peptideNMRNMR normalNuclear magnetic resonanceO2O2 saturationOxygenOAOA toesOsteoarthritisOCOCOral contraceptionORSAORSA infectionOxacillin-resistant staphylococcus aureusPPPhosphorusPANDASPANDASPediatric autoimmune neuropsychiatric disorders associated with streptococcal infectionPapPap smear abnormalPapanicolaou test(pap smear)PbPbLeadPCVPCV normalPacked cell volume (seeHematocrit)PCVPCVPacked cell volumePDGFPDGF receptor assayPlatelet-derived growth factor receptorPEFRPEFR normalPeak expiratory flow ratePETPET scan normalPositron-emission tomography(cerebral metabolic scan)PIDPID Pelvic inflammatory diseasePelvic inflammatory diseasePIHPIH Pregnancy induced hypertensionPregnancy induced hypertensionPNETPNET of bone localizedPrimitive neuroectodermal tumourPOEMSPOEMS syndromePolyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changesPPDPPD skin testPurified protein derivativePRPR shortenedProthrombin ratioPSAPSA normalProstate-specific antigenPSPPSP test normalPhenolsulfonphthaleinPTPT prolongedProthrombin timePTHPTH normalParathyroid hormonePTTPTT prolongedPartial thromboplastin timePUBleeding PUHealed PUBleeding peptic ulcerPeptic ulcer healedPUDPUDPeptic ulcer diseaseRARA latex testRheumatoid arthritisRBCRBC urineRed blood cells, red blood countRDWRDW increasedRed celldistribution widthREMREM sleep abnormalRapid eye movementRETRET gene mutationRearranged during transfectionRHRh isoimmunizationRhesus factorRPRRPR syphilis test positiveRapid plasma reagintestRSVRSV serology positiveRespiratory syncytial virusRTIRTIRespiratory tract infectionRUQRUQ painRight upper quadrant(see alsoregions of the abdomen)RVFRVFRight ventricular failureRVHRVHRight ventricular hypertrophySASA blockSinoatrial nodeSARSSARS virus test positiveSevere acute respiratory syndromeSCADSCAD deficiencyShort-chain acyl-coenzyme A dehydrogenaseSeSeSeleniumSGOTSGOT normalSerum glutamic oxaloacetic transaminaseSGPTSGPT normalSerum glutamic pyruvic transaminaseSIDSSIDS (Sudden infant death syndrome)Sudden infant death syndromeSLESLE syndrome aggravatedSystemic lupus erythematosusSMARTSMART syndromeStroke-like migraine attacks after radiation therapySPECTSPECT normalSingle photon emission computed tomographySTA-MCASTA-MCA bypass operationSuperficial temporal artery to middle cerebral arteryTARTAR syndromeThrombocytopenia-absent radiusTBTB spineTuberculosisTCTTCTThrombin clotting timeTdPTdP ventricular tachycardiaTorsades de pointesTIBCTIBC normalTotal iron binding capacityTLCTLC abnormalTLC decreasedTLC normalTotal lung capacityTMJTMJ syndromeTemporomandibular jointTOPTOP on mental groundsTermination of pregnancyTRAMTram flap breast reconstructionTransverse rectus abdominis myocutaneous flap (TRAM flap)TRAPTRAP sequence malformationTwin reversed arterial perfusionTSHTSH increasedThyroid stimulating hormoneTURBTTURBTTransurethral resection of bladder tumorUCUC aggravatedUlcerative colitisUGIUGI bleedUpper gastrointestinalUGTUGT1A1 gene mutationUridine diphosphoglucuronosyl transferase (UGT1A1) geneURTIURTI (upper respiratory tract infection)Upper respiratory tract infectionV/QV/Q scanVentilation/perfusion scanVCVCVital CapacityVDVDSexually Transmitted DiseaseVDRLVDRL positiveVenereal Diseases Research Laboratory(old test forsyphilis)VEGFVEGF assayVascular endothelial growth factorVGCCAnti-VGCC antibodyVoltage-gated calcium channelVIPVIP testVasoactive intestinal peptideVGKCAnti-VGKC antibodyVoltage-gated potassium channelVLCADVLCAD deficiencyVery long-chain acyl-coenzyme A dehydrogenaseVLDLVLDL raisedVery low density lipoproteinWBCWBC scanWhite blood cellWPWWPW syndromeWolff-Parkinson-White syndromewtWt lossWeight(whetherhuman weightor otherwise)ZnZn normalZincZnT8Anti-ZnT8 antibodyZinc transporter 8

&"-,Bold"&14MedDRA LLT Abbreviations / Acronyms

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