Development and First Evaluation of the new Patient Management and Documentation System MSDS 3D for Patients with Multiple SclerosisTjalf Ziemssen, Fabian Kratzsch, Marco Eulitz, Raimar Kempcke, Nina Kleiner, Heinz Reichmann MS@uniklinikum-dresden.de

Multiple Sclerosis center Dresden, Department of Neurology, University of Dresden, Germany

OBJECTIVE: To develop and evaluate a new Multiple Sclerosis patient

management software and hardware MSDS 3D for guideline-based

management and documentation of MS patients.

BACKGROUND: Multiple Sclerosis Documentation System (MSDS) has

been developed as standard MS documentation system in Germany since

2001 to generate data for the German MS registry. Up to now, there has

been no interface to patient and nurse data for multidimensional evaluation

(fatigue, depression, QoL, treatment management). As MS treatment

protocols get more and more complicated with implementation of new

drugs, MSDS 3D was developed to change the solely documentation to a

patient management system according current guidelines.

DESIGN/METHODS: In addition to the local hardware running MSDS, a

touch-screen and internet-based module (interface to patients mobile

phone) was developed for this project using ABS-VO technology to add

patients and nurses data using this interface. Special treatment and study

modules were developed with a defined visit schedule and mandatory

examinations which are documented and visualized by MSDS. Other

reports eg. from neuroradiologists, ophthalmologists are implemented

using the MSDS internet server. A touch screen terminal was developed

for collecting patients data and to provide information to the patient.

(A) Information from the patient (B) Information to the patient

RESULTS: MSDS 3DINTRODUCTION RESULTS: MS eMobile phone

PATIENTS & METHODS

CONCLUSIONS

MSDS 3D was adapted from eCRF forms used in clinical studies. For very

visit, certain modules are defined to each visit according a predefined

schedule according clinical pathways. Patients could be included in

different modules (eg. Natalizumab, clclinical studies).

The main screen includes the modules of the actual visit as well as the last

and next visit. In addition to the necessary modules, the obligatory

timeframe for visits is presented. If a visit does not take place, physiacian

and patient are reminded.

Main part of the system is the interactive patient terminal which can be

used to get information from the patient by intelligent adaptive

questionnaires. As well, information can be provided to the patient.

The MSDS 3D server can not only use the patient terminal in the MS

center, but can interact with the patient´s home computer or mobile phone.

So a first version of the MS eMobile phone was developed.

MS eMobile phone can be used to contact the patient or to be contacted by

the patient. It includes a calendear and an individualized information

platform.

In a pilot phase, MSDS 3D including the patient terminal was tested by 100

MS patients. The feedback was positive in more than 90% of the patients.

We have developed a new MS patient management system whgwhich was

positively evaluated by the MS patients in a pilot study. It is able to cope

with more complex treatment algorithms in MS patient care. To multicenter

studies arte on the way to evaluate the system in a university-based

scenario (REPABO) and a community neurology-based infrastructure (X-

Scale).

Main part of the system is the interactive patient terminal which can be

used to get information from the patient by intelligent adaptive

questionnaires. As well, information can be provided to the patient.