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A system overview of the Electronic Surveillance System for the Early
Notification of Community-based Epidemics
Presented at the 2004 Scientific Conferenceon Chemical & Biological Defense Research
15 November 2004
Joe Lombardo1, Rich Wojcik1, Wayne Loschen1
Jay Mansfield2
1 Johns Hopkins University Applied Physics Laboratory2 Walter Reed Army Institute of Research
Report Documentation Page Form ApprovedOMB No. 0704-0188
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1. REPORT DATE 15 NOV 2004
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4. TITLE AND SUBTITLE A system overview of the Electronic Surveillance System for the EarlyNotification of Community-based Epidemics
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6. AUTHOR(S) 5d. PROJECT NUMBER
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7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Johns Hopkins University Applied Physics Laboratory
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12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release, distribution unlimited
13. SUPPLEMENTARY NOTES See also ADM001849, 2004 Scientific Conference on Chemical and Biological Defense Research. Held inHunt Valley, Maryland on 15-17 November 2004 . , The original document contains color images.
14. ABSTRACT
15. SUBJECT TERMS
16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT
UU
18. NUMBEROF PAGES
25
19a. NAME OFRESPONSIBLE PERSON
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Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18
00.10.20.30.40.50.60.70.80.9
1
0 24 48 72 96 120 144 168
Incubation Period (Hours)
Prob
abili
ty o
fD
isea
se D
etec
tion
Time (days)
Num
ber D
ead
Sensor, Animal, or Human Indicators
105
(Anthrax)
t = 0
Fatalities WithEarly Warning
Military & CivilianFatalities With
Traditional Alerting
Gain of 2 days
Effective Treatment Period
Surveillance
Traditional DiseaseDetection
TIME!
Justification for Enhanced Surveillance(Anthrax)
Definition of Surveillance
• Epidemiologic Surveillance
- Ongoing and systematic collection, analysis, and interpretation of health data
- Used to determine need for public health action and to assess the effectiveness of programs
Syndromic Surveillance is the collection and analysis of pre-diagnosis information that lead to an estimation of the health status of the community
Syndromic surveillance uses health care indicators such as:
Emergency Room Chief ComplaintInternational Classification of Disease Billing CodesRequests for Specific Laboratory TestsOver the Counter Medications Sales
Grouped into specific syndromic categories such as:Respiratory GastrointestinalNeurologicalDermatologicalFeveretc.
Syndromic Surveillance Definition
Evolution of ESSENCE
PM Resident Project
DARPABioAlirtProgram
DTRA, JPEOCBDJSIPP
OSD HA
00
01
02
03
04
05
06
ESSENCE IWalter Reed
ESSENCE IINCR
ESSENCE IB(469 users)
ESSENCE II in JMeWS(CENTCOM)
ESSENCE IV*Military 9 Regions
(248 users)
ESSENCE IV*Civilian 9 States
(38 users)
Baseline Software*All Bases Critical Civilian
OSD HA*Med Surveillance
Operations
San Diego*BioNet Test bed
DHS*BioWatch Cities
Enhancement
Military Civilian
NCR*Disease Network
(72 users)
Maryland Y2KJohns Hopkins
Local /NCR
NationalDHS
VHA*National
Surveillance
00
01
02
03
04
05
06
Older Generation Currently OperationalEarly for FY05Future * Based on ESSENCE IV
ESSENCE IV* in JMeWS(CENTCOM)
WRAIR
Evolution of ESSENCE
PM Resident Project
DARPABioAlirtProgram
DTRA, JPEOCBDJSIPP
OSD HA
00
01
02
03
04
05
06
ESSENCE IWalter Reed
ESSENCE IINCR
ESSENCE IB(469 users)
ESSENCE II in JMeWS(CENTCOM)
ESSENCE IV*Military 9 Regions
(248 users)
ESSENCE IV*Civilian 9 States
(38 users)
Baseline Software*All Bases Critical Civilian
OSD HA*Med Surveillance
Operations
San Diego*BioNet Test bed
DHS*BioWatch Cities
Enhancement
Military Civilian
NCR*Disease Network
(72 users)
Maryland Y2KJohns Hopkins
Local /NCR
NationalDHS
VHA*National
Surveillance
00
01
02
03
04
05
06
Older Generation Currently OperationalEarly for FY05Future * Based on ESSENCE IV
ESSENCE IV* in JMeWS(CENTCOM)
WRAIR
ESSENCE IB Data Flow
World Wide Military Tricare Server Site JHU/APL
Prescription Meds
AmbulatoryEncounters
MilitaryTreatment Facilities
TriCareData
Archive
ESSENCEData
Archive
TemporalUnivariate
Alerts
Time SeriesData
Tables
ESSENCEFTP Server
ESSENCEWeb Server
Tables
Time Series
Alert Flags
Web PagesSAS Application
Data Collection
Evolution of ESSENCE
PM Resident Project
DARPABioAlirtProgram
DTRA, JPEOCBDJSIPP
OSD HA
00
01
02
03
04
05
06
ESSENCE IWalter Reed
ESSENCE IINCR
ESSENCE IB(469 users)
ESSENCE II in JMeWS(CENTCOM)
ESSENCE IV*Military 9 Regions
(248 users)
ESSENCE IV*Civilian 9 States
(38 users)
Baseline Software*All Bases Critical Civilian
OSD HA*Med Surveillance
Operations
San Diego*BioNet Test bed
DHS*BioWatch Cities
Enhancement
Military Civilian
NCR*Disease Network
(72 users)
Maryland Y2KJohns Hopkins
Local /NCR
NationalDHS
VHA*National
Surveillance
00
01
02
03
04
05
06
Older Generation Currently OperationalEarly for FY05Future * Based on ESSENCE IV
ESSENCE IV* in JMeWS(CENTCOM)
WRAIR
Worldwide U.S. Military (DOD GEIS)Worldwide U.S. Military (DOD GEIS)
PharmacyTri-Service Healthcare
ESSENCE IARCHIVE
ESSENCE IIArchive
ESSENCE IIPROCESSING
&NOTIFICATION
National Capital Area Military & CivilianNational Capital Area Military & CivilianAbsenteeism
Over-the-Counter Sales
Doctors’ Visits
Animal Health
Diagnostic Labs
HospitalEmergency
Room
LocalMilitary & Civ.
Users
Public HealthSurveillance
&Epidemiology
Hospitals&
EmergencyResponse
SecureWeb Site
NCA ONLYNCA ONLY
Integration of Military & Civilian Indicators for ESSENCE II
ClaimsData
ERChief
Complaint
EMS Data
PrescriptionMeds
DataArchive
TemporalUnivariate
TemporalMultivariate
SpatialUnivariate
SpatialMultivariate
Web Server
GISRaw DataDisplay
GISClusterDisplay
AlertFlag Lists
DataQuery
Interface
User InterfacesAnalysis
&Alerting
Major ESSENCE II-IV Components
Health ConditionIndicator Data Comms
Real-time HL-7PHIN MSXML, etc.
Secure FTPVPN, etc.
Text Parsing
DataCleansing
Archiving
Military Data
PHIN MSEtc.
Synthetic Data Used to Show Features of Alert List
Synthetic Syndrome Time Series
Analysis Options
Stacked Graph Example
Detector Comparisons
San Diego Tabletop, Synthetic DataNov 4th, Respiratory Distribution
Evolution of ESSENCE
PM Resident Project
DARPABioAlirtProgram
DTRA, JPEOCBDJSIPP
OSD HA
00
01
02
03
04
05
06
ESSENCE IWalter Reed
ESSENCE IINCR
ESSENCE IB(469 users)
ESSENCE II in JMeWS(CENTCOM)
ESSENCE IV*Military 9 Regions
(248 users)
ESSENCE IV*Civilian 9 States
(38 users)
Baseline Software*All Bases Critical Civilian
OSD HA*Med Surveillance
Operations
San Diego*BioNet Test bed
DHS*BioWatch Cities
Enhancement
Military Civilian
NCR*Disease Network
(72 users)
Maryland Y2KJohns Hopkins
Local /NCR
NationalDHS
VHA*National
Surveillance
00
01
02
03
04
05
06
Older Generation Currently OperationalEarly for FY05Future * Based on ESSENCE IV
ESSENCE IV* in JMeWS(CENTCOM)
WRAIR
NCR Disease Surveillance Network
ESSENCE IINCR
IntegratedSurveillance
MarylandSurveillance
System
VirginiaSurveillance
System
District of Columbia
SurveillanceSystem
Hospitals
Hospitals
Hospitals
Diagnostic Labs
Diagnostic Labs
Diagnostic Labs
Physician
Physician Physician
Environmental Samples
EPA
Over the Counter Sales
Animal Health
Absenteeism
ESSENCE INCR
Military Data
Tri-ServiceOutpatient Visits
Pharmacy DataFully Identified Records
De-Identified Records
De-Identified Data Sharing
Evolution of ESSENCE
PM Resident Project
DARPABioAlirtProgram
DTRA, JPEOCBDJSIPP
OSD HA
00
01
02
03
04
05
06
ESSENCE IWalter Reed
ESSENCE IINCR
ESSENCE IB(469 users)
ESSENCE II in JMeWS(CENTCOM)
ESSENCE IV*Military 9 Regions
(248 users)
ESSENCE IV*Civilian 9 States
(38 users)
Baseline Software*All Bases Critical Civilian
OSD HA*Med Surveillance
Operations
San Diego*BioNet Test bed
DHS*BioWatch Cities
Enhancement
Military Civilian
NCR*Disease Network
(72 users)
Maryland Y2KJohns Hopkins
Local /NCR
NationalDHS
VHA*National
Surveillance
00
01
02
03
04
05
06
Older Generation Currently OperationalEarly for FY05Future * Based on ESSENCE IV
ESSENCE IV* in JMeWS(CENTCOM)
WRAIR
• NSWCDD
• San Diego
• Camp Lejeune
• POPE AFB
• Ft. Gordon
• Ft. Campbell
• Barksdale AFB
• Ft. Lewis
• Warner Robins AFB
• NSWCDD
• San Diego
• Camp Lejeune
• POPE AFB
• Ft. Gordon
• Ft. Campbell
• Barksdale AFB
• Ft. Lewis
• Warner Robins AFB
BSL2 LAB
C
C2
MED
EMRCC
CCB
H
HHH
PHPH
Approx.Medical SurveillancePerimeter
ESSENCE IV
Hospn ED Visit Chief Complaints
Base
B
C
Bioaerosol sampler/sensorChemical sensor
JSIPP Sites
~50 mi Public Health
Hospitals
Web Site PortalsFor local users
TRICARE
PresumptiveIDs
LRNPH LAB
Confirmatory IDsnotional NationalData Sets
Web Site Portals
Medical Surveillance Component of Installation Protection
future
Evolution of ESSENCE
PM Resident Project
DARPABioAlirtProgram
DTRA, JPEOCBDJSIPP
OSD HA
00
01
02
03
04
05
06
ESSENCE IWalter Reed
ESSENCE IINCR
ESSENCE IB(469 users)
ESSENCE II in JMeWS(CENTCOM)
ESSENCE IV*Military 9 Regions
(248 users)
ESSENCE IV*Civilian 9 States
(38 users)
Baseline Software*All Bases Critical Civilian
OSD HA*Med Surveillance
Operations
San Diego*BioNet Test bed
DHS*BioWatch Cities
Enhancement
Military Civilian
NCR*Disease Network
(72 users)
Maryland Y2KJohns Hopkins
Local /NCR
NationalDHS
VHA*National
Surveillance
00
01
02
03
04
05
06
Older Generation Currently OperationalEarly for FY05Future * Based on ESSENCE IV
ESSENCE IV* in JMeWS(CENTCOM)
WRAIR
Integration of Military and Civilian Medical Surveillance in San Diego County
LaboratoryInformation
ManagementSystem
San Diego
BioWatchAir Sampling
S1
SnS4
S3
S2
IDRAE / ESSENCEPublic Health
Monitoring System
San Diego County Department of DefenseNavy Region Southwest
DoDLaboratoryAnalysisNetwork
GuardianEnvironmental
Monitoring
S1
Sn S4
S3
S2
ESSENCE IV DoD Health
Monitoring System
AmbulatoryData
PrescriptionMeds
ERChief
Complaint
ERChief
Complaint
EMSRuns
OTCMeds
PrescriptionMeds
PhysicianEncounter VA / HMO PHIN MS
Firewalls
Evolution of ESSENCE
PM Resident Project
DARPABioAlirtProgram
DTRA, JPEOCBDJSIPP
OSD HA
00
01
02
03
04
05
06
ESSENCE IWalter Reed
ESSENCE IINCR
ESSENCE IB(469 users)
ESSENCE II in JMeWS(CENTCOM)
ESSENCE IV*Military 9 Regions
(248 users)
ESSENCE IV*Civilian 9 States
(38 users)
Baseline Software*All Bases Critical Civilian
OSD HA*Med Surveillance
Operations
San Diego*BioNet Test bed
DHS*BioWatch Cities
Enhancement
Military Civilian
NCR*Disease Network
(72 users)
Maryland Y2KJohns Hopkins
Local /NCR
NationalDHS
VHA*National
Surveillance
00
01
02
03
04
05
06
Older Generation Currently OperationalEarly for FY05Future * Based on ESSENCE IV
ESSENCE IV* in JMeWS(CENTCOM)
WRAIR
Summary & Conclusions
• ESSENCE is the first system to integrate both military and civilian health indicator data for early notification of health events.
• ESSENCE versions are being used for public health surveillance of naturally occurring diseases as well as bioterrorist events.
• Public health surveillance has been around since the 14th century. Recent advances information technology and outbreak detection algorithms have advanced disease surveillance to become a important factor in identification and management of major health events.