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The animal health industry is actively working with governments and regulators around the world to try to overcome the many challenges still existing to ensure that veterinary medicines can be delivered quickly and effectively when needed Salmonella costs the USA as much as $3bn annually World Zoonosis Day 6 TH July 2015 A history of the most notorious zoonotic diseases i To find out more on how protecting our animals will help protect our world visit www.HealthforAnimals.org/who-we-are/zoonoses-outbreaks or join the debate on Twitter @HealthforAnimals Global examples of emerging & re-emerging infectious diseases The economic impact of recent zoonotic disease outbreaks Up to 75% of all human diseases are zoonotic in origin, meaning they are naturally transmitted between animals and humans Currently there are over 200 identified zoonotic diseases that represent a clear threat to our health and the welfare of animals Up to 20% of global animal production is lost to disease The impact of zoonotic epidemics from 1995 to 2008, many of them preventable, exceeded $120 billion globally Some zoonotic diseases such as rabies can be eradicated Preventive veterinary medicines & the widespread use & development of vaccines play an increasingly important role globally in effective disease control 200+ 75% $ $120Bn 20% A historical timeline of some of the most notorious zoonotic diseases demonstrates a highly probable increase in incidences over the years. This is most likely due to a growing population, increased globalisation, travel, international trade, pet ownership, socio-economic factors and climate change. Black Death (plague) Europe 1347 Yellow fever South America 16th century Salmonella USA 1885 Ebola Africa 1976 Lyme disease USA 1975 H5N1 (avian influenza) China 1997 Nipah virus Malaysia 1999 Rabies Italy 1546 Brucellosis Malta 1850s Cryptosporidiosis USA 1907 Influenza pandemic Global 1918 HIV / AIDS USA 1983 BSE Europe Mid 1980s H1N1 Swine influenza USA 2009 SARS (Severe acute respiratory syndrome) China 2003 MERS-CoV Middle East Respiratory Syndrome coronavirus 2012 E-coli Germany 1885 1200 AD 150 125 50 25 0 1990 1995 2000 2005 2010 2015 1300 1400 1500 1600 1700 1800 1900 2000 RISK Newly emerging Re-emerging/resurging Deliberately emerging Estimated cost ($BN) Lassa fever Hepatitis C Lyme disease Cyclosporiasis vCJD Cryptosporidiosis HIV Enterovirus 71 Hendra virus Nipah virus H5N1 influenza E. coli 0157:H7 E. coli 0157:H7 Whitewater arroyo virus Anthrax bioterrorism Hantavirus pulmonary syndrome SARS Dengue Yellow fever Cholera Marburg hemorrhagic fever Ebola hemorrhagic fever Plague Human monkeypox Human monkeypox West Nile virus Rift Valley fever Diptheria Vancomycin- resistant Staphylococcus aureus Vancomycin-resistant Staphylococcus aureus Drug-resistant malaria Multidrug-resistant tuberculosis Typhoid fever Credit: Bio Economic Research Associates, LLC ©., 12 August 2008. SARS and the New Economics of Biosecurity, 2003 Ebola Africa 2014-15 $1.6bn Lyme disease USA 2002 $200m H5N1 Avian influenza Worldwide 1997 $30bn Nipah virus Asia 1999 $350-400m BSE UK 1995 $5bn BSE USA & Canada 2003-04 $6.5bn SARS China, Hong Kong, Singapore, Canada 2003 $30-50bn E-coli 0157:H7 USA 2010 $489-993mn H1N1 Swine influenza Worldwide 2009 $45-55bn Rabies Worldwide 2013 $124bn

A history of the most notorious zoonotic diseases

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The animal health industry is actively working with governments and regulators around the world to try

to overcome the many challenges still existing to ensure that veterinary medicines can be delivered

quickly and effectively when needed

Salmonella costs the USA

as much as $3bn annually

World Zoonosis Day6TH July 2015

A history of the mostnotorious zoonotic diseases

i To find out more on how protecting our animals will help protect our world visit www.HealthforAnimals.org/who-we-are/zoonoses-outbreaks or join the debate on Twitter @HealthforAnimals

Global examples of emerging & re-emerging infectious diseases

The economic impact of recent zoonotic disease outbreaks

Up to 75% of all human diseases are zoonotic

in origin, meaning they are naturally

transmitted between animals and humans

Currently there are over 200 identified

zoonotic diseases that represent a clear threat

to our health and the welfare of animals

Up to 20% of global animal production is

lost to disease

The impact of zoonotic epidemics from 1995

to 2008, many of them preventable, exceeded

$120 billion globally

Some zoonotic diseases such as rabies

can be eradicated

Preventive veterinary medicines & the widespread

use & development of vaccines play an increasingly

important role globally in effective disease control

200+75% $$120Bn20%

A historical timeline of some of the most notorious zoonotic diseases demonstrates a highly probable increase in incidences over the years. This is most likely due to a growing population, increased globalisation, travel, international trade, pet ownership, socio-economic factors and climate change.

Black Death (plague) Europe 1347

Yellow fever South America16th century

Salmonella USA 1885

EbolaAfrica1976

Lyme diseaseUSA1975

H5N1 (avian influenza) China1997

Nipah virusMalaysia1999

Rabies Italy1546

Brucellosis Malta1850s

Cryptosporidiosis USA1907

Influenza pandemicGlobal1918

HIV / AIDSUSA1983

BSEEuropeMid 1980s

H1N1 Swine influenzaUSA 2009

SARS (Severe acute respiratory syndrome) China 2003

MERS-CoV Middle East Respiratory Syndrome coronavirus2012

E-coli Germany 1885

1200 AD

150

125

50

25

0

1990 1995 2000 2005 2010 2015

1300

1400

1500

1600

1700

1800

1900

2000

RISK

Newly emerging Re-emerging/resurging Deliberately emerging

Estim

ated

cost

($BN

)

Lassa fever

Hepatitis C

Lyme disease

Cyclosporiasis

vCJD

Cryptosporidiosis

HIV

Enterovirus 71

Hendra virus

Nipah virus

H5N1influenza

E. coli0157:H7

E. coli 0157:H7

Whitewater arroyo virus

Anthraxbioterrorism

Hantavirus pulmonary syndrome

SARS

Dengue Yellow fever Cholera Marburg hemorrhagic fever

Ebola hemorrhagic fever

Plague

Human monkeypox

Human monkeypox

West Nile virus

Rift Valley fever

Diptheria

Vancomycin-resistant

Staphylococcus aureus

Vancomycin-resistantStaphylococcus aureus

Drug-resistant malariaMultidrug-resistant tuberculosis

Typhoid fever

Credit: Bio Economic Research Associates, LLC ©., 12 August 2008. SARS and the New Economics of Biosecurity, 2003

EbolaAfrica

2014-15$1.6bnLyme disease

USA2002

$200m

H5N1 Avian influenza

Worldwide1997$30bn

Nipah virusAsia1999

$350-400m

BSE UK1995 $5bn

BSEUSA & Canada

2003-04$6.5bn

SARS China, Hong Kong, Singapore, Canada

2003 $30-50bn

E-coli 0157:H7USA2010

$489-993mn

H1N1 Swine influenza

Worldwide2009

$45-55bn

Rabies Worldwide

2013$124bn