27
RESEARCH Open Access A comparative study on shared-use medicines in Tibetan and Chinese medicine Ming-ming Zhao 1,2 , Ke-ru Wang 1 , Rui Gu 1* and Shi-hong Zhong 3 Abstract Background: Tibetan medicine (TM) and traditional Chinese medicine (TCM) are two independent traditional medical systems. Due to geographical factors, the development of Tibetan medicinal theory is relatively independent, but there are still many shared-use medicines in TM and TCM. However, a thorough and comparative study on those medicines is still absent. This study listed shared-use medicines by TM and TCM and analyzed the similarities and dissimilarities of these two medical systems. This paper also aimed to understand mutual influences like the shared history of TM and TCM and to roughly outline the exchanging process between them. Methods: Shared-use medicines in TM and TCM were listed alphabetically. Information on the scientific name, material name, medicinal parts, and medical efficacy were extracted from publications. Shared-use medicines were grouped according to medicinal properties and medicinal parts used by TM and TCM. The historical origin and current status of clinical prescriptions of shared-use medicines were analyzed. Results: A total of 136 shared-use medicines in TM and TCM were listed. Shared-use medicines that were used for a similar purpose in TM and TCM accounted for 14% of the total, while those used for different purposes accounted for 49% of the total, with some of the latter being commonly used in TCM. Shared-use medicinal herbs that originated from both Tibetan and Han regions accounted for 49% of the total, and those that were imported from South Asia and Southeast Asia were frequently observed in TM. Conclusion: Owing to its unique geographical location and cultural diversity, the Tibetan region played a role as a development cradle for various traditional medicinal theories and knowledge. Medicinal knowledge was exchanged between TM and TCM during their parallel independent growth. Shared-use medicines in TM and TCM were mostly determined by flora similarity and medicinal trade, and they marked significant differences in their medicinal properties. However, medicines that were used for similar purposes in TM and TCM presented obvious commercial medicinal characteristic as well as the same chemical profile. The Tibetan region not only provided medicinal usage knowledge of TCM, but also served as a supply of medicinal resources attributing to high altitudelocations. Keywords: Tibetan medicine, Traditional Chinese medicine, Shared-use medicines, Comparative study Background Tibetan medicine (TM) is rich in medicinal resources, approximately 80% of which are produced in the Qing- hai-Tibet Plateau, with significant ethnic culture and regional biological distinctness, which is reflected in it being a culturally traditional medicine. Tibetan medicine presents obvious characteristics of national culture and distinct ecological-geographic conditions [1]. It is gener- ally believed in medical documents that during the inheritance and development process, TM has continu- ously acquired knowledge and absorbed beneficial ingre- dients from Chinese traditional medicine (TCM), Indian Ayurveda medicine, and Arabic medicine. Earlier re- search on the history of Tibetan medicine [2] showed that Chinese and Tibetan medicines were widely ex- changed during the Tubo period, while there are few documents about medical communication occurring between Han and Tibetan people at a later period. Princess Wencheng of the early Tang Dynasty brought a hundred prescriptions for the treatment of four hun- dred and four diseases, five kinds of diagnostic methods, © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. * Correspondence: [email protected] 1 Chengdu University of Traditional Chinese Medicine, No. 1166, Liu-tai Road, Wenjiang District, Chengdu 611173, China Full list of author information is available at the end of the article Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 https://doi.org/10.1186/s13002-019-0320-5

A comparative study on shared-use medicines in Tibetan and Chinese medicine · 2019. 10. 18. · Tibetan medicine (TM) is rich in medicinal resources, approximately 80% of which are

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  • RESEARCH Open Access

    A comparative study on shared-usemedicines in Tibetan and Chinese medicineMing-ming Zhao1,2, Ke-ru Wang1, Rui Gu1* and Shi-hong Zhong3

    Abstract

    Background: Tibetan medicine (TM) and traditional Chinese medicine (TCM) are two independent traditionalmedical systems. Due to geographical factors, the development of Tibetan medicinal theory is relativelyindependent, but there are still many shared-use medicines in TM and TCM. However, a thorough and comparativestudy on those medicines is still absent. This study listed shared-use medicines by TM and TCM and analyzed thesimilarities and dissimilarities of these two medical systems. This paper also aimed to understand mutual influenceslike the shared history of TM and TCM and to roughly outline the exchanging process between them.

    Methods: Shared-use medicines in TM and TCM were listed alphabetically. Information on the scientific name,material name, medicinal parts, and medical efficacy were extracted from publications. Shared-use medicines weregrouped according to medicinal properties and medicinal parts used by TM and TCM. The historical origin andcurrent status of clinical prescriptions of shared-use medicines were analyzed.

    Results: A total of 136 shared-use medicines in TM and TCM were listed. Shared-use medicines that were used fora similar purpose in TM and TCM accounted for 14% of the total, while those used for different purposesaccounted for 49% of the total, with some of the latter being commonly used in TCM. Shared-use medicinal herbsthat originated from both Tibetan and Han regions accounted for 49% of the total, and those that were importedfrom South Asia and Southeast Asia were frequently observed in TM.

    Conclusion: Owing to its unique geographical location and cultural diversity, the Tibetan region played a role as adevelopment cradle for various traditional medicinal theories and knowledge. Medicinal knowledge was exchangedbetween TM and TCM during their parallel independent growth. Shared-use medicines in TM and TCM were mostlydetermined by flora similarity and medicinal trade, and they marked significant differences in their medicinalproperties. However, medicines that were used for similar purposes in TM and TCM presented obvious commercialmedicinal characteristic as well as the same chemical profile. The Tibetan region not only provided medicinal usageknowledge of TCM, but also served as a supply of medicinal resources attributing to “high altitude” locations.

    Keywords: Tibetan medicine, Traditional Chinese medicine, Shared-use medicines, Comparative study

    BackgroundTibetan medicine (TM) is rich in medicinal resources,approximately 80% of which are produced in the Qing-hai-Tibet Plateau, with significant ethnic culture andregional biological distinctness, which is reflected in itbeing a culturally traditional medicine. Tibetan medicinepresents obvious characteristics of national culture anddistinct ecological-geographic conditions [1]. It is gener-ally believed in medical documents that during the

    inheritance and development process, TM has continu-ously acquired knowledge and absorbed beneficial ingre-dients from Chinese traditional medicine (TCM), IndianAyurveda medicine, and Arabic medicine. Earlier re-search on the history of Tibetan medicine [2] showedthat Chinese and Tibetan medicines were widely ex-changed during the Tubo period, while there are fewdocuments about medical communication occurringbetween Han and Tibetan people at a later period.Princess Wencheng of the early Tang Dynasty brought“a hundred prescriptions for the treatment of four hun-dred and four diseases, five kinds of diagnostic methods,

    © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, andreproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link tothe Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

    * Correspondence: [email protected] University of Traditional Chinese Medicine, No. 1166, Liu-tai Road,Wenjiang District, Chengdu 611173, ChinaFull list of author information is available at the end of the article

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 https://doi.org/10.1186/s13002-019-0320-5

    http://crossmark.crossref.org/dialog/?doi=10.1186/s13002-019-0320-5&domain=pdfhttp://orcid.org/0000-0003-3120-6290http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/publicdomain/zero/1.0/mailto:[email protected]

  • six kinds of medical devices, and four kinds of theory onmedicine...” to Tibet, following her marriage with KingSongtsan Gambo of Tibet. A Han doctor translatedthem into the Medical Encyclopedia, and later, trad-itional Chinese medicine (TCM) practitioner Han Wen-hai contributed Small Sporadic External Therapy andFearless Weapons coauthored with Scorpion and PersianDoctors during the period of Chi Dezuzan (704–745).Princess Jincheng dedicated a variety of medical books,such as Jumbo Drugs by Han doctor Zhang Song andHuman Body Torso translated by doctor Zambia Lahafrom Yutian, in the Western Region, to the Tibetan king.During the period of Akamatsu Dezan, Yuewang DrugClinic was translated into the Tibetan language, andthree famous Chinese medical practitioners, includingDongsong Gangwa of the Tang Dynasty, were recruited.At the end of the eighth century, Yutuo YuandanGongbu was sent by the Tibetan King to the mainland,such as Wutai mountain, to study TCM [3].Based on the above historical literature, many scholars

    believe that Tibetan medicine has been largely influ-enced by traditional Chinese medicine during its devel-opment. An earlier article [4] revealed that there weremany connections in the historical background, theoret-ical system, and application of prescriptions betweenTM and TCM, and TM possesses its own unique fea-tures in addition to what it shares in common withTCM regarding medicinal properties, pharmacology,clinical medical practices, prescriptions, and patent med-icines. However, we still do not know much about thesimilarity or dissimilarity of the two traditional medicinalsystems, and a thorough study on shared-use medicinesin TM and TCM is still absent. In view of this, the maingoals of the present paper are to systematically listshared-use medicines in TM and TCM, evaluate the dif-ferences of the medicinal parts and medical efficacies,analyze the mutual influence of history and the exchan-ging process of the two medical systems, and discuss thehistorical and cultural background leading to thoseshared-use medicines.

    MethodsTCM use a total of 12,807 [5] different types of medi-cine, and TM use 3105 [6] species according to docu-mentation. However, comprehensive statistics on thesetotal varieties cannot reflect the clinical status of TMand TCM. Luckily, earlier, Zhong Guoyue compiled 502medicinal materials that are used in the Tibetan medi-cine prescriptions. The present paper listed commonlyused Tibetan medicines based on his study, includingpublications such as the Ministry of Health of thePeople's Republic of China • Tibetan Medicine, Book 1[7] and the Tibetan Medicine Standards for Six Provinces[8]. According to The Collection of Chinese Herbal

    Medicines [9], shared-use medicines, including animal,plant, mineral, and fungi resources, were documented al-phabetically. Information on the scientific name, medi-cinal parts, and medical efficacy was extracted frompublications, such as Chinese Pharmacopoeia, Book 1(2015 edition) [10], The Collection of Chinese HerbalMedicines [9], Chinese Medicine Dictionary [11], Minis-try of Health of the People's Republic of China • TibetanMedicine, Book 1 [7], Tibetan Medicine Standards forSix Provinces [8], The Four-Part Medical Classics [11],Crystal Beads [12], Tibetan Medicine Chronicles [13],Chinese Materia Medica (Tibetan Medicine) [14], Ti-betan medicine in China [15], and Tibetan Herbals inChina [16], and was pooled together. Information on thefamily and genus was analyzed based on Flora ReipublicaePopularis Sinica [17], and Higher Plants of China [18].The shared-use medicines recorded by ChinesePharmacopoeia, Book 1 (2015 edition) [10] and the Med-ical Standards of the Ministry of Health of the People's Re-public of China • Tibetan Medicine, Book 1 [7] weremarked in this paper.According to the medicinal property, the shared-use

    medicines in TM and TCM were divided into fivecategories: classes I, II, III, IV, and V. The shared-usemedicines with the same purpose fell into class I; theshared-use medicines with medicinal usage by TM basic-ally covering that by TCM fell into class II; the shared-use medicines with medicinal usage by TCM basicallycovering that by TM fell into class III; the shared-usemedicines that were used for different purposes fell intoclass IV; and the shared-use medicines with partial over-lapping medical effects in the two medicinal system fellinto class V.According to the medicinal part differences, the

    shared-use medicines were divided into five types: clas-ses A, B, C, D, and E. The shared-use medicines withsame medicinal parts in TM and TCM fell into class A;the shared-use medicines with medicinal parts in TMcovering that in TCM fell into class B; the shared-usemedicines with medicinal parts in TCM covering that inTM fell into class C; the shared-use medicines with to-tally different medicinal parts in the two medical systemsfell into class D; and the shared-use medicines with par-tial overlapping medicinal parts in the two medicinalsystem fell into class E. The above information weregiven in Tables 1, 2, 3, 4 and 5.Based on the plant distribution recorded in the Flora

    Reipublicae Popularis Sinica and other research on me-dicinal materials, the origins of the shared-use medicinescould be roughly divided into the following five types:the first category included varieties that were distributedin both the Tibetan region and in the areas that weremainly covered by the Central Plains throughout history;the second category included varieties that were mainly

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 2 of 27

  • Table

    1TheInform

    ationof

    classI

    No.

    Family

    Scientific

    name

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreated

    inTC

    M

    Disease

    grou

    pstreated

    intm

    1Apidae

    Apiscerana

    Fabr*

    蜂蜜

    *Hon

    eyBeew

    ax,

    hone

    ybee

    Indicatio

    ns:epigastric

    pain

    alleviated

    after

    mealsor

    bypressing

    ;dry

    coug

    h;constip

    ation;

    externaluseforsores,scalds,and

    burns[10]

    Indicatio

    ns:d

    rycoug

    hwith

    outph

    legm

    ,intestinaldryconstip

    ation,

    coun

    teract

    toxicity

    ofacon

    itum;externalu

    sefor

    ulcersin

    themou

    th,sores,b

    urns,and

    scalds

    [8]

    BDigestive,

    respiratory

    disorders

    Digestiveand

    respiratory

    disorders

    2Asteraceae

    Auckland

    iae

    radix

    木香

    *Ro

    otRo

    otIndicatio

    n:abdo

    minaldisten

    sion

    and

    epigastricpain,d

    iarrhe

    a,dysentery,

    indige

    stion,

    loss

    ofappe

    tite[10]

    Indicatio

    n:abdo

    minaldisten

    sion

    and

    epigastricpain,vom

    iting

    ,diarrhe

    a,and

    pneumon

    ia[8]

    ADigestive

    disorders

    Digestive

    disorders

    3Con

    volvulaceae

    Cuscuta

    chinensid

    sLam.*

    菟丝

    子*

    Seed

    Seed

    Indicatio

    ns:impo

    tence,seminalem

    ission

    ,dripping

    ofurineafterurination,

    enuresis,

    frequ

    enturination,

    aching

    andweakness

    oftheloinsandknees,blurredvision

    and

    tinnitus;threaten

    edabortio

    ndu

    eto

    deficiencyof

    thekidn

    ey;d

    iarrhe

    adu

    eto

    hypo

    functio

    nof

    thespleen

    andthekidn

    ey;

    anexternaluseforvitiligo[10]

    Indicatio

    ns:p

    ainin

    theloinsand

    knees,im

    potence,seminalem

    ission

    ,strang

    uriawith

    turbid

    discharge,

    abno

    rmalvaginal

    discharge,diarrhea,and

    tinnitus[14]

    AReprod

    uctive

    system

    disorders

    Reprod

    uctive

    system

    disorders

    4Elapidae

    Bung

    arus

    multicinctus

    Blyth

    银环

    蛇Meat

    Meat

    Rheumatic,stroke,he

    miplegia,convulsion

    ,spasm,tetanus,lep

    rosy,and

    scab

    [10]

    Rheumatic,h

    emiplegia[19];con

    vulsion,

    spasm,tetanus,syphilis,and

    scab

    [13]

    ANervous

    system

    ailm

    ents

    Nervous

    system

    ailm

    ents

    5Fabaceae

    Dalbergia

    odorifera

    T.Che

    n

    降香

    *Heartwoo

    dHeartwoo

    dHem

    atem

    esis,traum

    atiche

    morrhinia,

    hypo

    chon

    driacpain

    dueto

    stagnatio

    nof

    liver

    qi,vom

    iting

    ,and

    stom

    achpain

    [10]

    Liverdiseases,lim

    bed

    ema[13]

    ACirculatory

    system

    disorders

    Circulatory

    system

    disorders

    6Pipe

    raceae

    Piperlong

    umL*

    荜拔

    *Fruit

    Fruit

    Indicatio

    ns:epigastric

    pain,vom

    iting

    and

    diarrhea

    caused

    bycold,m

    igraine;and

    externalusefortoothache[10]

    Indicatio

    ns:rLung

    diseases

    incold

    synd

    rome,precordialandabdo

    minal

    pain

    with

    cold

    sensation,

    nausea

    and

    vomiting

    ,borbo

    rygm

    us,and

    diarrhea

    [8]

    ADigestive

    disorders

    Digestive

    disorders

    7Po

    lygo

    naceae

    Rheum

    officinaleBaill.*

    药用

    大黄*

    Rootsand

    rhizom

    eRo

    otsand

    rhizom

    eIndicatio

    ns:fever

    with

    constip

    ation,

    retention

    offecesandabdo

    minalpain;d

    ysen

    tery;

    jaun

    dice

    caused

    bydamp-he

    at;h

    ematem

    esis,

    epistaxis,inflammationof

    eyes

    andsore

    throat

    dueto

    heat

    inbloo

    d;appe

    ndicitiswith

    abdo

    minalpain;b

    oils,sores

    andabscess;

    amen

    orrhagedu

    eto

    bloo

    dstasis;traum

    atic

    injuries;he

    morrhagefro

    mtheup

    per

    gastrointestinaltract;andexternalusefor

    scalds

    andbu

    rns[10]

    Indicatio

    ns:con

    stipationdu

    eto

    excessive

    heat,ind

    igestio

    ndisten

    sion

    synd

    rome,

    tene

    smus,jaund

    icein

    damp-he

    atsynd

    rome,bloo

    dstasis,amen

    orrhea,

    sores,andbo

    ils[8]

    ADigestive

    disorders

    Digestive

    disorders

    8Po

    lygo

    naceae

    Rheum

    palmatum

    L.*

    掌叶

    大黄*

    Rootsand

    rhizom

    eRo

    otsand

    rhizom

    eThesameas

    above[10]

    Thesameas

    above

    ADigestive

    disorders

    Digestive

    disorders

    9Po

    lygo

    naceae

    Rheum

    tang

    uticum

    Maxim

    .ex

    Rege

    l*

    唐古

    特大黄

    *Ro

    otsand

    rhizom

    eRo

    otsand

    rhizom

    eThesameas

    above[10]

    Thesameas

    above

    ADigestive

    disorders

    Digestive

    disorders

    10Ru

    taceae

    Zantho

    xylum

    bung

    eanu

    mMaxim

    .*

    花 椒*《藏

    标》

    Exocarp

    andseed

    Exocarp

    andfru

    itIndicatio

    ns:epigastric

    pain

    cold

    sensation,

    vomiting

    anddiarrhea;abd

    ominalpain

    dueto

    intestinalparasitosis;ascariasis;and

    Indicatio

    ns:g

    astrop

    athy,fun

    giand

    tricho

    mon

    ad;externalu

    sefor

    derm

    atosis[15]

    EDigestive,

    immun

    esystem

    Digestiveand

    immun

    esystem

    ailm

    ents

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 3 of 27

  • Table

    1TheInform

    ationof

    classI(Co

    ntinued)

    No.

    Family

    Scientific

    name

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreated

    inTC

    M

    Disease

    grou

    pstreated

    intm

    externaluseforitching

    ineczema[10]

    ailm

    ents

    11Selagine

    llaceae

    Selaginella

    pulvinata

    (Hoo

    k.et

    Grev.)Maxim

    .

    垫状

    卷柏

    Who

    leplant

    Who

    leplant

    Indicatio

    ns:amen

    orrhea,h

    ematoche

    zia,

    andarchop

    toma[10]

    Indicatio

    ns:amen

    orrhea,m

    assesin

    theabdo

    men

    ,hem

    afecia,and

    prolapse

    ofrectum

    [8]

    AReprod

    uctive

    anddige

    stive

    disorders

    Reprod

    uctiveand

    dige

    stive

    disorders

    12ApiaceaeA

    piaceae

    Ferula

    sinkian

    gensisK.

    M.She

    n*

    新疆

    阿魏*

    Resin

    Resin

    Indicatio

    ns:ind

    igestio

    n,cong

    estio

    n,and

    stom

    achpain

    dueto

    parasitic

    diseases

    [10]

    Indicatio

    ns:ind

    igestio

    n,cong

    estio

    n,and

    stom

    achpain

    dueto

    parasitic

    diseases

    [8]

    ADigestive

    disorders

    Digestive

    disorders

    13ApiaceaeA

    piaceae

    Ferula

    fukanensisK.

    M.She

    n*

    阜康

    阿魏*

    Resin

    Resin

    Indicatio

    ns:ind

    igestio

    n,cong

    estio

    n,and

    stom

    achpain

    dueto

    parasitic

    diseases

    [10]

    Indicatio

    ns:ind

    igestio

    n,cong

    estio

    n,and

    stom

    achpain

    dueto

    parasitic

    diseases

    [8]

    ADigestive

    disorders

    Digestive

    disorders

    14Zing

    iberaceae

    Alpinia

    katsum

    adai

    Hayata*

    草豆

    蔻*

    Seed

    pellets

    expe

    lled

    Seed

    pellets

    expe

    lled

    Indicatio

    ns:accum

    ulationof

    damp-cold

    inthespleen

    andthestom

    achmanifested

    byep

    igastricdisten

    tion,

    andpain

    andcold

    feelingaccompanied

    with

    belching

    ,nausea,

    vomiting

    ,and

    anorexia[10]

    Indicatio

    ns:spleendiseases

    and

    gastropathy[15]

    ADigestive

    disorders

    Digestive

    disorders

    15Zing

    iberaceae

    Alpinia

    officinarum

    Hance*

    高良

    姜*

    Rhizom

    eRh

    izom

    eIndicatio

    ns:epigastric

    pain

    with

    cold

    sensation;

    vomiting

    ,belching,

    andacid

    regu

    rgitatio

    ndu

    eto

    cold

    inthe

    stom

    ach[10]

    Indicatio

    ns:epigastric

    pain

    with

    cold

    sensation,

    vomiting

    anddiarrhea

    dueto

    cold

    inthespleen

    andstom

    ach;

    loss

    ofappe

    tite[8]

    ADigestive

    disorders

    Digestive

    disorders

    16Zing

    iberaceae

    Kaem

    pferia

    galang

    aL.*

    山柰

    *Rh

    izom

    eRh

    izom

    eIndicatio

    ns:d

    yspe

    psiaaccompanied

    with

    epigastricdisten

    sion

    ,pain,

    andcold

    feeling[10]

    Indicatio

    ns:com

    plicationof

    badkan

    diseases

    andrlu

    ngdiseases

    [15]

    ADigestive

    disorders

    Digestive

    disorders

    17Zing

    iberaceae

    Amom

    umtsaoko

    Crevost

    etLemair

    草果

    *Fruit

    Fruit

    Indicatio

    n:abdo

    minaldisten

    sion

    and

    epigastricpain,vom

    iting

    ,malaria,and

    fever[10]

    Toremovecold

    inthespleen

    and

    stom

    ach;

    prom

    otedige

    stion[13]

    ADigestive

    disorders

    Digestive

    disorders

    18Zing

    iberaceae

    Zing

    iber

    officinale

    Rosc.*

    姜*

    Rhizom

    eRh

    izom

    eIndicatio

    ns:com

    mon

    cold

    caused

    byexterio

    rwind-cold.Vom

    iting

    dueto

    cold

    inthestom

    ach[10]

    Indicatio

    ns:b

    adkandiseases,rlung

    diseases,abd

    omen

    pain

    dueto

    cold

    inthespleen

    andstom

    ach,

    vomiting

    anddiarrhea,cou

    ghanddyspne

    adu

    eto

    cold

    inthelung

    ,and

    rheumatoid

    arthralgia[8]

    ARespiratory,

    dige

    stive

    disorders

    Respiratory,

    dige

    stive,and

    immun

    esystem

    ailm

    ents

    19——

    Cordyceps

    冬虫

    夏草

    Fung

    iFung

    iPu

    lmon

    arytube

    rculosis,cou

    gh,h

    emop

    tysis,

    dyspne

    aof

    deficiencytype

    ,night

    sweatin

    g,em

    ission

    ,impo

    tence,andsorene

    ss-tiredof

    waistandknee

    [10]

    Lung

    diseases,emission

    ,and

    impo

    tence

    [14]

    ARespiratory

    and

    reprod

    uctive

    system

    disorders

    Respiratory

    and

    reprod

    uctive

    system

    disorders

    *Sha

    red-usemed

    icines

    recorded

    bythe20

    15ed

    ition

    ofCh

    inaPh

    armacop

    oeia

    Class

    Ainclud

    edtheshared

    -use

    med

    icines

    with

    thesamemed

    icinal

    partsin

    TMan

    dTC

    M;class

    Binclud

    edtheshared

    -use

    med

    icines

    with

    med

    icinal

    partsin

    TMcoverin

    gthat

    inTC

    M;class

    Cinclud

    edtheshared

    -use

    med

    icines

    with

    med

    icinal

    partsin

    TCM

    coverin

    gthat

    inTM

    ;class

    Dinclud

    edtheshared

    -use

    med

    icines

    with

    totally

    differen

    tmed

    icinal

    partsin

    thetw

    omed

    ical

    system

    s;an

    dclassE

    includ

    edtheshared

    -use

    med

    icines

    with

    partialo

    verla

    ppingmed

    icinal

    partsin

    thetw

    omed

    icinal

    system

    s

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 4 of 27

  • Table

    2Inform

    ationon

    classII

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreatedin

    TM

    1Aristolochiaceae

    Aristolochia

    debilis

    Sieb

    .et

    Zucc*

    马兜铃*

    Root

    Aerialp

    arts

    Indicatio

    ns:d

    yspn

    eaasthma,coug

    handbloo

    dysputum

    dueto

    heat

    inthelung

    ;bleed

    ing,

    andsw

    ollenand

    painfulh

    emorrhoids

    dueto

    heat

    inthelargeintestine[10]

    Indicatio

    ns:b

    lood

    disease,clun

    gdisease,

    liver

    disease,foorgandisease,badkan

    diseases,p

    lagu

    edisease[15]

    DRespiratory

    anddige

    stive

    disorders

    Respiratory

    anddige

    stive

    disorders

    2Cervidae

    Cervus

    elaphu

    sLinn

    aeus

    马鹿

    Antler

    Antlerand

    testis

    Indicatio

    ns:impo

    tence,em

    ission

    ,carbun

    cle,sores,andsw

    elling[10]

    Indicatio

    ns:vertig

    o,im

    potence,flaccid

    limbs,d

    eafness,andmetrorrhagia[15]

    BReprod

    uctive

    and

    locomotor

    system

    ailm

    ents

    Reprod

    uctive

    andurinary

    system

    disorders

    3Cervidae

    Cervus

    nippon

    Temminck

    梅花鹿

    Antler

    Antlerand

    testis

    Indicatio

    ns:impo

    tence,em

    ission

    ,carbun

    cle,sores,andsw

    elling[10]

    Indicatio

    ns:vertig

    o,im

    potence,flaccid

    limbs,and

    deafne

    ss,m

    etrorrhagia[15]

    BReprod

    uctive

    and

    locomotor

    system

    ailm

    ents

    Reprod

    uctive

    andurinary

    system

    disorders

    4Asteraceae

    Inularacemosa

    J.D.H

    ooker*

    土木香*

    Roots

    Roots

    Indicatio

    ns:d

    istend

    ingpain

    inthe

    chest,hypo

    chon

    driaandep

    igastrium,

    vomiting

    anddiarrhea;b

    ruiseor

    sudd

    ensprain

    ofthecheatwith

    pain

    durin

    gbreathing;

    abortio

    nthreat

    [10]

    Toremovehe

    atfro

    mbloo

    d[12]

    ADigestive

    disorders

    Immun

    esystem

    ailm

    entsand

    dige

    stive

    disorders

    5Asteraceae

    Dolom

    iaea

    souliei

    (Franche

    t)C.

    Shih

    川木香

    Roots

    Roots

    Indicatio

    ns:abd

    ominaldisten

    sion

    ,gu

    rglingsoun

    d,anddiarrhea

    [10]

    Indicatio

    ns:lossof

    appe

    tite,gastric

    ulcer,

    abdo

    minaldisten

    sion

    ,and

    rheumatism

    [15]

    ADigestive

    disorders

    Digestive

    disorders

    6Crassulaceae

    Rhodiola

    crenulata(Hoo

    k.f.et

    Thom

    s.)H.

    Ohb

    a*

    大花红

    景天*

    Rootsand

    rhizom

    eRo

    otsand

    rhizom

    eIndicatio

    ns:con

    strictio

    nin

    thechest

    with

    heartpain,apo

    plexy,lassitu

    de,

    andasthma[10]

    Indicatio

    ns:nausea,vomiting

    ,cyano

    sis

    onthelipsandpalm

    dueto

    clim

    atic

    sickne

    ss;lossof

    streng

    th,che

    stdistress,

    insomniaanddream-disturbed

    sleep,

    andalso

    used

    fortube

    rculosis[14]

    ADigestiveand

    nervou

    ssystem

    ailm

    ents

    Digestive,

    andne

    rvou

    ssystem

    ailm

    ents

    7Brassicaceae

    Raph

    anus

    sativus

    L.萝卜

    Aerial

    parts

    Roots

    Toprom

    otedige

    stionandstop

    thirst,

    removehe

    at,and

    coun

    teract

    toxicity.

    Indicatio

    ns:m

    assesin

    theabdo

    men

    ,ob

    stinateph

    legm

    ,dyspe

    psiadu

    eto

    stom

    achcold,eye

    disease,consum

    ptive

    thirst,constip

    ation,andinfluen

    za[16]

    DDigestive

    disorders

    Digestive

    disorders

    8Fabaceae

    Medicago

    ruthenica(L.)

    Trautv.

    花苜蓿

    Seed

    Who

    leplant

    Toremovetoxic-he

    at,relieve

    coug

    h,andarrestbleeding

    [9]

    Indicatio

    ns:b

    oilsandmeasles,cou

    ghdu

    eto

    heat

    inthelung

    [7].Externaluse

    toelim

    inateinflammationandarrest

    bleeding

    [8]

    BRespiratory

    disorders

    Respiratory

    disorders

    9Liliaceae

    Allium

    sativum

    L.大蒜

    Bulb

    Bulb

    Indicatio

    ns:carbu

    ncle,furun

    cles,skin

    disease,ph

    thisis,cou

    gh,d

    iarrhe

    a,and

    dysentery[10]

    Indicatio

    ns:carbu

    ncletoxin,skin

    diseases,

    cold,hem

    orrhoids,urin

    aryretention,and

    leprosy[14]

    ARespiratory

    disorders

    Urin

    ary,

    respiratory

    anddige

    stive

    disorders

    10Malvaceae

    Malva

    crisp

    a冬葵*

    Roots,

    Flow

    erand

    Indicatio

    ns:enu

    resis,ed

    ema,thirst,

    Indicatio

    ns:anu

    resis,go

    norrhe

    a,ed

    ema,

    DUrin

    ary

    Urin

    ary,

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 5 of 27

  • Table

    2Inform

    ationon

    classII(Con

    tinued)

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreatedin

    TM

    Linn

    .*stem

    ,seed

    ,and

    leaf

    fruits

    andurinaryinfectionwith

    oliguria

    [10]

    thirst,andseminalem

    ission

    [7]

    system

    disorders

    reprod

    uctive

    system

    disorders

    11Myristicaceae

    Myristica

    fragran

    sHou

    tt.*

    肉豆蔻*

    Kernel

    Kernel

    Indicatio

    ns:d

    eficiency-cold

    ofthe

    spleen

    andstom

    achwith

    persistent

    diarrhea,epigastric

    andabdo

    minal

    disten

    sion

    andpain,ano

    rexia,and

    vomiting

    [10]

    Indicatio

    ns:rhe

    umatiche

    artdisease,

    abdo

    minalpain

    dueto

    cold

    inthe

    stom

    ach,dyspep

    sia,feelingof

    anxietyin

    theqi

    deficiencysynd

    rome,and

    epidem

    icfebrile

    disease[16]

    ADigestive

    disorders

    Circulatory

    system

    disorders

    12Myrtaceae

    Ewgewia

    caryophyllata

    Thun

    b.*

    丁香

    *Flow

    erbu

    dFlow

    erbu

    dIndicatio

    ns:hiccup,

    vomiting

    ,diarrhea,and

    abdo

    minalpain

    with

    cold

    sensation[10]

    Indicatio

    ns:hiccup,

    vomiting

    ,diarrhe

    a,abdo

    minalpain

    with

    cold

    sensation,and

    impo

    tence[8]

    ADigestive

    disorders

    Digestive

    disorders

    13Pedaliaceae

    Sesamum

    indicum

    L.胡麻《藏

    标》

    Seed

    Seed

    Toreplen

    ishtheliver

    andkidn

    ey,

    tonifybloo

    d,moisten

    intestines,and

    prom

    otelactation[10]

    Indicatio

    ns:w

    indsynd

    romeof

    head

    and

    dizzinessdu

    eto

    yinde

    ficiencyof

    the

    liver

    andkidn

    ey,con

    stipationin

    deficiencysynd

    rome[8]

    AReprod

    uctive

    andne

    rvou

    ssystem

    ailm

    entsand

    dige

    stive

    disorders

    Reprod

    uctive

    andne

    rvou

    ssystem

    ailm

    entsand

    dige

    stive

    disorders

    14Sciurid

    aeTrogopterus

    xanthipes

    复齿鼯

    鼠Dry

    excrem

    ent

    Excrem

    ent,

    meat

    Toactivatebloo

    dcirculationand

    elim

    inatebloo

    dstasis,and

    arrest

    bleeding

    [10]

    Excrem

    ent:prom

    otetheflow

    ofbloo

    danddred

    gethemeridians,elim

    inate

    bloo

    dstasisandpain,use

    forstom

    ach

    pain,d

    ysmen

    orrhea,and

    amen

    orrhea;

    meat:gyne

    cologicald

    iseases,and

    oxytocin,con

    tracep

    tion[16]

    BDigestive,

    reprod

    uctive

    and

    locomotor

    system

    ailm

    ents

    Digestive,

    reprod

    uctive

    system

    disorders

    15Pipe

    raceae

    Pipernigrum

    L.*

    胡椒*

    Fruit

    Fruit

    Indicatio

    ns:vom

    iting

    ,abd

    ominalpain,

    diarrhea

    andloss

    ofappe

    titedu

    eto

    cold

    inthestom

    ach;inappe

    tence,

    andep

    ilepsywith

    profuseph

    legm

    [10]

    Indicatio

    ns:b

    adkandiseases,cold

    phlegm

    ,ind

    igestio

    n,vomiting

    and

    dysenterydu

    eto

    cold,and

    abdo

    minal

    pain

    with

    cold

    sensation[8]

    ADigestive

    disorders

    Digestive

    disorders

    16Ranu

    nculaceae

    Acon

    itum

    pend

    ulum

    Busch

    铁棒锤

    Tube

    rTube

    r,seed

    ling,

    roots

    Todispelwindandrelieve

    pain,

    removebloo

    dstasis,arrestbleeding

    ,redu

    cesw

    elling,

    andremovetoxin[9]

    Indicatio

    ns:rlung

    diseases,colddiseases,

    yellow

    fluid

    diseases,lep

    rosy,and

    epilepsy[7]

    BLocomotor

    system

    ailm

    ents

    Nervous

    system

    ailm

    ents

    17Ru

    biaceae

    Rubiacordifolia

    L.*

    茜草*

    Roots

    Roots,

    rhizom

    e,andwho

    leplant

    Indicatio

    ns:spittingof

    bloo

    d,ep

    istaxis,abno

    rmaluterinebleeding

    ,traumaticbleeding

    ;amen

    orrhea,

    arthralgia,and

    traumaticsw

    ellingand

    pain

    [10]

    Indicatio

    ns:w

    holegrass:pn

    eumon

    ia,

    neph

    ritisandtricho

    mon

    alvaginitis;roo

    t;spittingof

    bloo

    d,ep

    istaxis,

    hematoche

    zia,abno

    rmaluterine

    bleeding

    ,men

    strualdisorders,

    men

    oxen

    iaabdo

    minalpain,ecchymom

    apain,traum

    ainjury,and

    bloo

    dydysentery[12]

    BDigestive,

    locomotor

    system

    ailm

    ents

    Digestive,

    reprod

    uctive

    and

    locomotor

    system

    ailm

    ents

    18Euph

    orbiaceae

    Euph

    orbia

    fischeriana

    Steude

    l*

    狼毒*

    Roots

    Roots

    Tocauseurination,remove

    indige

    stion,andkillparasites[10]

    Indicatio

    ns:b

    oilsandsores,scrofula,

    externaluseforde

    rmatitis,andulceratio

    n[7]

    AIm

    mun

    esystem

    ailm

    ents

    Respiratory

    andim

    mun

    esystem

    ailm

    ents

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 6 of 27

  • Table

    2Inform

    ationon

    classII(Con

    tinued)

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreatedin

    TM

    19ApiaceaeA

    piaceae

    Coriand

    rum

    sativum

    L.芫荽

    Fruits

    Fruits

    Indicatio

    ns:m

    easles,cold,

    indige

    stion,

    andloss

    ofappe

    tite[9]

    Indicatio

    ns:ind

    igestio

    n,loss

    ofappe

    tite,

    thirst,gastric

    ulcer,measles,cold,

    stom

    achdiseases,and

    dysentery[7]

    ADigestive

    disorders

    Digestive

    disorders

    20Zing

    iberaceae

    Amom

    umkravan

    hPierre

    exGagne

    p

    白豆蔻

    Seed

    Fruits

    Toprom

    otetheflow

    ofqi

    andarrest

    vomiting

    ,warm

    thestom

    ach,and

    prom

    otedige

    stion[10]

    Indicatio

    ns:heartdisorder,g

    astrop

    athy,

    andne

    phropathycharacterized

    bycold

    [16]

    ADigestive

    disorders

    Digestive,

    urinary

    system

    disorders

    21Zing

    iberaceae

    Alpiniagalang

    a(L.)Willd

    大高良

    姜Fruits

    Fruits,

    rhizom

    eTo

    stim

    ulatethefunctio

    nalactivity

    ofthestom

    achby

    expe

    lling

    cold,

    prom

    otetheflow

    ofqi,and

    relieve

    pain

    [10]

    Indicatio

    ns:fruit;ne

    phropathy,

    gastropathy[15]

    Rhizom

    e;precordialand

    abdo

    minalpain

    with

    cold

    sensation;

    indige

    stiondu

    eto

    stom

    ach-cold,loin

    pain

    inkidn

    eyde

    ficiencysynd

    rome,and

    lung

    abscess[16]

    BDigestive

    disorders

    Digestive,

    respiratory

    disorders

    *Sha

    red-usemed

    icines

    recorded

    bythe20

    15ed

    ition

    ofCh

    inaPh

    armacop

    oeia

    Class

    Ainclud

    edtheshared

    -use

    med

    icines

    with

    thesamemed

    icinal

    partsin

    TMan

    dTC

    M;class

    Binclud

    edtheshared

    -use

    med

    icines

    with

    med

    icinal

    partsin

    TMcoverin

    gthat

    inTC

    M;class

    Cinclud

    edtheshared

    -use

    med

    icines

    with

    med

    icinal

    partsin

    TCM

    coverin

    gthat

    inTM

    ;class

    Dinclud

    edtheshared

    -use

    med

    icines

    with

    totally

    differen

    tmed

    icinal

    partsin

    thetw

    omed

    ical

    system

    s;an

    dclassEinclud

    edtheshared

    -use

    med

    icines

    with

    partialo

    verla

    ppingmed

    icinal

    partsin

    thetw

    omed

    icinal

    system

    s

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 7 of 27

  • Table

    3Inform

    ationon

    classIII

    No.

    Family

    Scientific

    name

    Chine

    sename

    Partsused

    inTC

    MParts

    used

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreatedin

    TM

    1Thym

    elaeaceae

    Stellera

    cham

    aejasm

    eLinn

    .*

    瑞香狼

    毒*

    Roots

    Roots

    Tocauseurination,removeindige

    stion,andkill

    parasites[10]

    Indicatio

    ns:b

    oilsandsores,

    scrofula,externalu

    seforde

    rmatitis,

    andulceratio

    n[7]

    ADigestive

    disorders

    Immun

    esystem

    ailm

    ents

    2Juglandaceae

    Juglan

    sregia

    L.胡桃

    Kernel,

    exocarpand

    leaf

    Exocarp

    andleaf

    Kernel:toreinforcekidn

    ey,relieve

    asthma,use

    fortin

    nitus,coug

    h,andasthmain

    kidn

    eyde

    ficiencysynd

    rome,seminalem

    ission

    ,lumbago

    ,tym

    panitis,and

    astrictio

    n;Exocarp:

    relieve

    swellinganditching

    ,tracheitis,

    lepraalph

    os,tinea

    capitis,sores,and

    boils;

    Leaf:leucorrhe

    a[10]

    Indicatio

    ns:rlung

    diseases,spasm

    oftend

    onsandcollaterals,aching

    andweaknessof

    theloinsand

    knees,constip

    ation,seminal

    emission

    ,and

    impo

    tence[8]

    CRespiratory

    and

    reprod

    uctive

    system

    disorders

    Reprod

    uctive

    anddige

    stive

    disorders

    3Fabaceae

    Glycyrrhiza

    inflata

    Bat.

    胀果甘

    草*

    Rhizom

    eandroot

    Rhizom

    eandroot

    Indicatio

    ns:hypofun

    ctioning

    ofspleen

    and

    stom

    ach,coug

    h,palpitatio

    n,sw

    ollensore

    throat,and

    sores[10]

    Indicatio

    ns:lun

    gdiseases

    [15]

    ADigestiveand

    respiratory

    disorders

    Respiratory

    disorders

    4Fabaceae

    Glycyrrhiza

    uralensis

    Fisch.

    甘草*

    Rhizom

    eandroot

    Rhizom

    eandroot

    Indicatio

    ns:hypofun

    ctioning

    ofspleen

    and

    stom

    ach,coug

    h,palpitatio

    n,sw

    ollensore

    throat,and

    sores[10]

    Indicatio

    ns:lun

    gdiseases

    [15]

    ADigestiveand

    respiratory

    disorders

    Respiratory

    disorders

    5Legu

    minosae

    Trigon

    ella

    foenum

    -grecum

    L.

    葫芦巴

    Seed

    Seed

    Indicatio

    ns:coldsynd

    romeof

    thekidn

    eydu

    eto

    yang

    deficiencymarkedby

    pain

    and

    coldne

    ssin

    thelower

    abdo

    men

    ;hernia;and

    weaknessanded

    emaof

    thelegs

    caused

    bycold-dam

    p[10]

    Indicatio

    ns:m

    assform

    ationin

    the

    abdo

    men

    ,discomfortand

    disten

    sion

    inthechestand

    hypo

    chon

    driacregion

    s,andkakke

    dueto

    cold-dam

    pness[8]

    AReprod

    uctive

    system

    disordersand

    dige

    stive

    disorders

    Digestive

    disorders

    6Liliaceae

    Polygona

    tum

    sibiricum

    Redouté*

    黄精*

    Rhizom

    eRh

    izom

    eIndicatio

    ns:w

    eaknessof

    thespleen

    andthe

    stom

    achmarkedby

    lassitu

    de,d

    ryne

    ssin

    the

    mou

    thandanorexia;d

    rycoug

    hdu

    eto

    deficiencyof

    yinof

    lung

    ;deficiencyof

    vital

    essenceandbloo

    d;andwastin

    g-thirstcaused

    byinternalhe

    at[10]

    Indicatio

    ns:various

    deficiency,dry

    coug

    hhydrod

    ipsia,andthirst[8]

    ADigestiveand

    respiratory

    disorders

    Respiratory

    disorders

    7Arecaceae

    Areca

    catechuL*

    槟榔*

    Exocarp

    Seed

    Indicatio

    ns:taeniasis,ascariasis,and

    fasciolopsiasis;abdo

    minalpain

    dueto

    intestinalparasitosis;diarrhea

    andtene

    smus

    dueto

    accumulationof

    undige

    sted

    food

    ;ed

    emaandweaknessof

    thelegs;and

    malaria

    [10]

    Indicatio

    ns:kidne

    ydisease,

    toothache,andparasitic

    diseases

    [14]

    DDigestiveand

    urinarysystem

    disorders

    Reprod

    uctive

    anddige

    stive

    disorders

    8Po

    lygo

    naceae

    Rumex

    nepalensis

    Spreng

    .

    尼泊尔

    酸模

    Rootsand

    leaf

    Roots

    Toremovetoxic-he

    at,arrestbleeding

    ,relax

    bowels,andkillfung

    iand

    tricho

    mon

    ad[10]

    Indicatio

    ns:b

    oilsandeczema[7]

    CDigestive

    disordersand

    immun

    esystem

    ailm

    ents

    Immun

    esystem

    ailm

    ents

    9Ranidae

    Rana

    chensin

    ensis

    中国林

    蛙Meat

    Meat

    Indicatio

    ns:p

    alpitatio

    n,insomnia,nigh

    tsw

    eatin

    g,andhe

    mop

    tysis[10]

    Indicatio

    ns:neurasthe

    nia[12]

    BRespiratory

    disorders

    Urin

    aryand

    nervou

    ssystem

    ailm

    ents

    10Ranu

    nculaceae

    Coptis

    黄连*

    Rhizom

    eRh

    izom

    eIndicatio

    ns:vom

    iting

    ,diarrhe

    a,jaun

    dice,

    Indicatio

    ns:infectio

    usdisease,

    ADigestive

    Immun

    e

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 8 of 27

  • Table

    3Inform

    ationon

    classIII(Con

    tinued)

    No.

    Family

    Scientific

    name

    Chine

    sename

    Partsused

    inTC

    MParts

    used

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreatedin

    TM

    chinensis

    Franch.

    hype

    rthe

    rmia,insom

    niadu

    eto

    restlessne

    ss,

    toothache,thirst,skin

    diseases,and

    eczema

    [10]

    anthrax,dysentery,andincised

    wou

    nd[13]

    disorders

    system

    ailm

    ents

    11Ru

    taceae

    Zantho

    xylum

    simulan

    sHance.

    野花椒

    Root

    and

    fruit

    Exocarp

    Todispelcold

    from

    thespleen

    andstom

    ach,

    relieve

    pain,killfung

    iand

    tricho

    mon

    ad,and

    preven

    tim

    preg

    natio

    n[10]

    Indicatio

    ns:g

    astrop

    athy,fun

    giand

    tricho

    mon

    ad,and

    externalusefor

    derm

    atosis[15]

    DDigestiveand

    immun

    esystem

    ailm

    ents

    Digestiveand

    immun

    esystem

    ailm

    ents

    12Solanaceae

    Lycium

    chinense

    Mill.*

    枸杞*

    Root

    and

    bark

    Fruits

    Indicatio

    ns:g

    eneralde

    bilitywith

    deficiencyof

    vitalessen

    cewith

    manifestations

    ofaching

    oftheloin

    andknees,dizziness,andtin

    nitus;

    diabetes

    byinternalhe

    at;ane

    mia;and

    impairedvision

    [10]

    Indicatio

    ns:heartfebrile

    disease

    andgyne

    copathy[15]

    DReprod

    uctive

    system

    disorders

    Circulatory

    system

    disordersand

    respiratory

    ailm

    ents

    13Urticaceae

    Urtica

    laetevirens

    Maxim

    .

    宽叶荨

    麻Who

    leplant,roots,

    andseed

    Aerial

    parts

    Indicatio

    ns:rhe

    umatism

    arthralgia,p

    ostpartum

    andinfantile

    convulsion

    ,infantileparalytic

    sequ

    el,hypertension,dyspep

    sia,stoo

    latresia.

    Externaluseforurticariainitiallyandsnakebite

    [10]

    Indicatio

    ns:chron

    iche

    artdiseases

    anddyspep

    siadu

    eto

    rlung

    diseases

    [7]

    CLocomotor,

    nervou

    ssystem

    ailm

    entsand

    dige

    stive

    disorders

    Digestive

    disorders

    14——

    Sulfur*

    硫黄*

    Natural

    elem

    ent

    sulfur

    minerals

    Natural

    elem

    ent

    sulfur

    minerals

    Indicatio

    ns:externalu

    seforscabiesandfavus,

    abscessesdu

    eto

    cold

    andph

    legm

    retention

    andmalignant

    ulcers,oraladm

    inistrationfor

    impo

    tencewith

    cold

    lower

    extrem

    ities,and

    asthmaor

    constip

    ationof

    deficiency-cold

    type

    [10]

    Indicatio

    ns:carbu

    ncles,soresand

    boils,tetter,andleprosyand

    externaluseformange

    ,malignant

    sore,p

    ruritus

    [15]

    AReprod

    uctive

    anddige

    stive

    disorders

    Circulatory

    system

    disordersand

    immun

    esystem

    ailm

    entailm

    ents

    *Sha

    red-usemed

    icines

    recorded

    bythe20

    15ed

    ition

    ofCh

    inaPh

    armacop

    oeia

    Class

    Ainclud

    edtheshared

    -use

    med

    icines

    with

    thesamemed

    icinal

    partsin

    TMan

    dTC

    M;class

    Binclud

    edtheshared

    -use

    med

    icines

    with

    med

    icinal

    partsin

    TMcoverin

    gthat

    inTC

    M;class

    Cinclud

    edtheshared

    -use

    med

    icines

    with

    med

    icinal

    partsin

    TCM

    coverin

    gthat

    inTM

    ;class

    Dinclud

    edtheshared

    -use

    med

    icines

    with

    totally

    differen

    tmed

    icinal

    partsin

    thetw

    omed

    ical

    system

    s;an

    dclassEinclud

    edtheshared

    -use

    med

    icines

    with

    partialo

    verla

    ppingmed

    icinal

    partsin

    thetw

    omed

    icinal

    system

    s

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 9 of 27

  • Table

    4Inform

    ationon

    classIV

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreated

    inTM

    1Acanthaceae

    Adha

    toda

    vasica

    Nees

    鸭嘴花

    Who

    leplant

    Twig

    Todispelwindandactivatebloo

    dcirculation;elim

    inatebloo

    dstasis

    andrelieve

    pain;and

    re-jo

    intthe

    bone

    [10]

    Indicatio

    ns:b

    lood

    andliver

    heat-

    relateddiseases,m

    khris

    padiseases,

    traumaticinjury,b

    oils,swelling,

    and

    pain

    [15]

    ALocomotor

    system

    ailm

    ents

    Digestive,

    locomotor

    system

    ailm

    ents

    2Araceae

    Acorus

    calamus

    L菖蒲

    Rhizom

    eRh

    izom

    eTo

    dispelwindto

    resolvethe

    exterio

    r,clearhe

    atandremove

    dampn

    ess,relieve

    coug

    hresolve

    phlegm

    ,elim

    inatebloo

    dstasis,and

    redu

    cesw

    elling[10]

    Indicatio

    ns:d

    yspe

    psia,d

    iphthe

    ria,

    boils,and

    sores[7]

    ARespiratory

    and

    locomotor

    system

    ailm

    ents

    Digestive

    disorders

    3Berberidaceae

    Sino

    podoph

    yllum

    hexand

    rum

    (Royle)Ying

    .

    桃儿七

    Rootsand

    rhizom

    eFruits

    Indicatio

    ns:rhe

    umaticarthritis,

    traumaticinjury,cou

    ghdu

    eto

    wind-

    cold,and

    men

    oxen

    ia[10]

    Indicatio

    ns:stasissynd

    romeof

    wom

    en,fetalde

    ath,mazischesis,and

    amen

    orrhea

    [8]

    DIm

    mun

    esystem

    ailm

    ents,

    locomotor,

    respiratory,and

    reprod

    uctive

    system

    disorders

    Reprod

    uctive

    system

    disorders

    4Bo

    mbacaceae

    Gossampinu

    smalabarica

    (DC.)M

    ern

    木棉花*

    Flow

    erFlow

    erIndicatio

    ns:d

    iarrhe

    a,dysentery,and

    hemorrhoids

    [10]

    Indicatio

    ns:lun

    gandliver

    diseases

    [15]

    ADigestive

    disorders

    Digestive

    disorders

    5Bo

    vidae

    Bostaurus

    domesticus

    Gmelin

    *

    牛黄*

    Dry

    gallstone

    sDry

    gallstone

    sIndicatio

    ns:impairm

    entof

    consciou

    snessin

    febrile

    diseases

    and

    stroke;infantileconvulsion

    ,epilepsy,

    mania;sorethroat,ulcersin

    the

    mou

    th;carbu

    ncles,andbo

    ils[10]

    Indicatio

    ns:p

    lagu

    eep

    idem

    icdisease

    andliver-heatsynd

    rome[11]

    ANervous

    system

    ailm

    entsand

    respiratory

    disorders

    Digestive

    disorders

    6Bu

    rseraceae

    Boszvelliacarterii

    Birdw

    *乳香树*

    Resin

    Resin

    Indicatio

    ns:stomachpain,

    dysm

    enorrhea,amen

    orrhea,

    rheumatism,traum

    aticinjury,

    carbun

    cle,andsore

    [10]

    Indicatio

    ns:skindiseases

    [14]

    ACirculatory

    system

    disordersand

    locomotor

    system

    ailm

    ents

    Immun

    esystem

    ailm

    ents

    7Caryoph

    yllaceae

    Arenaria

    kansuensisMaxim

    甘肃蚤

    缀Who

    leplant

    Who

    leplant

    Tono

    urishyinandtonifybloo

    d,replen

    ishthekidn

    ey,and

    reinforce

    thebo

    ne[10]

    Indicatio

    ns:p

    neum

    oniaandvario

    uslung

    diseases

    [7]

    ADigestive

    disorders

    Respiratory

    disorders

    8Cervidae

    Moschus

    berezovskiiFlerov

    林麝

    Secretions

    insw

    eet

    bursaof

    malebo

    dy

    Secretions

    insw

    eet

    bursaof

    malebo

    dy,

    meat,testis,

    feces

    Torestoreconsciou

    snessand

    activatebloo

    dcirculation,stim

    ulate

    men

    struation,redu

    cesw

    elling,

    and

    relieve

    pain

    [10]

    Indicatio

    ns:stroke,syncop

    edu

    eto

    phlegm

    ,sud

    denattack

    ofprecordial

    andabdo

    minalpain,kidne

    ydisease,

    massesin

    theabdo

    men

    ;externalu

    sefortraumaticinjury,carbu

    ncle-

    abscess,andfuruncles[15]

    BNervous,

    circulatoryand

    locomotor

    system

    ailm

    ents

    Nervous

    system

    ailm

    ents,

    locomotor,

    reprod

    uctive,

    anddige

    stive

    disorders

    9Cervidae

    Moschus

    moschiferus

    Linn

    aeus

    原麝

    Secretions

    insw

    eet

    bursaof

    Secretions

    insw

    eet

    bursaof

    Torestoreconsciou

    snessand

    activatebloo

    dcirculation,stim

    ulate

    men

    struation,redu

    cesw

    elling,

    and

    Indicatio

    ns:stroke,syncop

    edu

    eto

    phlegm

    ,sud

    denattack

    ofprecordial

    andabdo

    minalpain,kidne

    ydisease,

    BNervous,

    circulatoryand

    locomotor

    Nervous,

    locomotor,

    reprod

    uctive,

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 10 of 27

  • Table

    4Inform

    ationon

    classIV

    (Con

    tinued)

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreated

    inTM

    malebo

    dymalebo

    dy,

    meat,testis,

    andfeces

    relieve

    pain

    [10]

    massesin

    theabdo

    men

    ;externalu

    sefortraumaticinjury,carbu

    ncle-

    abscess,andfuruncles[15]

    system

    ailm

    ents

    anddige

    stive

    disorders

    10Cervidae

    Mochu

    ssifan

    icus

    Buchne

    r马麝

    Secretions

    insw

    eet

    bursaof

    malebo

    dy

    Secretions

    insw

    eet

    bursaof

    malebo

    dy,

    meat,testis,

    andfeces

    Torestoreconsciou

    snessand

    activatebloo

    dcirculation,stim

    ulate

    men

    struation,redu

    cesw

    elling,

    and

    relieve

    pain

    [10]

    Indicatio

    ns:stroke,syncop

    edu

    eto

    phlegm

    ,sud

    denattack

    ofprecordial

    andabdo

    minalpain,kidne

    ydisease,

    massesin

    theabdo

    men

    ;externalu

    sefortraumaticinjury,carbu

    ncle-

    abscess,andfuruncles[15]

    BNervous,

    circulatoryand

    locomotor

    system

    ailm

    ents

    Nervous

    system

    ailm

    ents,

    locomotor,

    reprod

    uctive,

    anddige

    stive

    disorders

    11Com

    bretaceae

    Term

    inalia

    chebulaRetz.*

    诃子*

    Fruit

    Fruit

    Indicatio

    ns:p

    rotracteddiarrhea

    with

    hematoche

    ziaor

    prolapse

    ofthe

    rectum

    andchroniccoug

    hwith

    sore

    throat

    andho

    arsene

    ss[10]

    Indicatio

    ns:rlung

    diseases,b

    lood

    diseases,m

    khris

    padiseases,and

    badkan

    diseases

    [15]

    ADigestive,

    urinary,and

    respiratory

    disorders

    Digestiveand

    circulatory

    system

    disorders

    12Com

    bretaceae

    Term

    inalia

    cheb

    ulaRetz.var.

    tomen

    tella

    (Kurz)

    C.B.C

    larke

    绒毛诃

    子Fruit

    Fruit

    Tocheckdiarrhea

    andchronic

    coug

    handsubd

    uetheup

    wardqi

    [10]

    Indicatio

    ns:rlung

    diseases,b

    lood

    diseases,m

    khris

    padiseases,and

    badkan

    diseases

    [15]

    ADigestiveand

    reprod

    uctive

    system

    disorders

    Digestive

    disorders

    13Asteraceae

    Cartha

    mus

    tinctoriusL.*

    红花*

    Flow

    erFlow

    erIndicatio

    ns:amen

    orrhea,

    dysm

    enorrhea;reten

    tionof

    lochia;

    abdo

    minalmasses;traumaticinjuries,

    sores,andulcerswith

    swellingand

    pain

    [10]

    Indicatio

    ns:p

    neum

    onia,hep

    atitis,

    bloo

    dhe

    at,carbu

    ncles,traumatic

    injury,and

    gyne

    copathia[14]

    AReprod

    uctive

    andlocomotor

    system

    ailm

    ents

    Respiratory,

    locomotorand

    reprod

    uctive

    system

    disorders

    14Asteraceae

    Saussurea

    laniceps

    Hand.-

    Mazz.

    绵头雪

    莲花

    Who

    leplant

    Who

    leplant

    Totonifykidn

    eyandreinforceyang

    ;regu

    late

    men

    struationby

    arresting

    bleeding

    [9]

    Indicatio

    ns:headtrauma,anthrax,

    pricking

    pain,g

    ynecop

    athy,

    rheumaticarthritis,and

    stroke.

    Externaluseforsw

    elling[7]

    AReprod

    uctive

    system

    disorders

    Reprod

    uctive

    andim

    mun

    esystem

    ailm

    ents

    15Cucurbitaceae

    Lagena

    riasiceraria(M

    olina)

    Standl.

    葫芦

    Exocarp,

    seed

    Seed

    Tocauseurination,redu

    cesw

    elling.

    Usedin

    edem

    a,ascites,and

    tube

    rculou

    scervicallymph

    aden

    itis

    [9]

    Indicatio

    ns:d

    ysen

    tery

    dueto

    heat,

    pulm

    onarydisease,andrash

    [7]

    CUrin

    aryand

    respiratory

    disorders

    Respiratory

    andim

    mun

    esystem

    ailm

    ents

    16Dipterocarpaceae

    Dipterocarpus

    turbinatus

    Gaertn.f.*

    龙脑香*

    Resin

    Resin

    Indicatio

    ns:lossof

    consciou

    snessin

    stroke

    andattack

    ofno

    xiou

    sfactors,

    syncop

    edu

    eto

    violen

    texcitemen

    tor

    postpartum

    anem

    ia;inflammation

    ofeyes,aph

    tha,andsw

    ollensore

    throat

    [10]

    Indicatio

    ns:highfeverandchronic

    hotnessfever[14]

    ANervous

    system

    ailm

    entsand

    respiratory

    disorders

    Respiratory

    disorders

    17Equidae

    Equusasinus

    L.驴

    Skin

    Bloo

    d,meat

    Indicatio

    ns:hem

    ostasis[10]

    Indicatio

    ns:rhe

    umatism

    [14]

    DCirculatory

    system

    disorders

    Nervous

    system

    ailm

    ents

    18Gen

    tianaceae

    Gentiana

    crassicaulis

    Duthieex

    Burk

    *

    粗茎秦

    艽*

    Roots

    Flow

    er,

    roots

    Indicatio

    ns:rhe

    umaticor

    rheumatoid

    arthritiswith

    muscularcontracture

    andsevere

    jointpain;fever

    recurring

    Indicatio

    ns:ton

    sillitis,urticaria,

    carbun

    cle,andrheumatoidarthritis

    [13]

    BNervous,

    locomotor

    system

    Respiratory

    andim

    mun

    esystem

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 11 of 27

  • Table

    4Inform

    ationon

    classIV

    (Con

    tinued)

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreated

    inTM

    intheafternoo

    n,andfeverin

    infants

    with

    malnu

    trition

    [10]

    ailm

    ents

    ailm

    ents

    19Gen

    tianaceae

    Gentiana

    straminea

    Maxim

    麻花艽

    Roots

    Flow

    er,

    who

    leplant

    Todispelwindanddampn

    essand

    subd

    uede

    ficient

    heat

    [10]

    Indicatio

    ns:g

    astroe

    nteritis,he

    patitis,

    andcholecystitis[7,8]

    BRespiratory

    ailm

    ents

    Digestive

    disorders

    20Gramineae

    Bambu

    sae

    Con

    cretio

    Silicea*

    天竺黄

    Secretion

    Secretion

    Indicatio

    ns:com

    a,stroke,and

    epilepsyandconvulsion

    inchildren

    [10]

    Indicatio

    ns:lun

    gdiseases

    [8]

    ANervous

    system

    ailm

    ents

    Respiratory

    disorders

    21Gramineae

    Saccharum

    sine

    nseRo

    xb.

    甘蔗加

    工成红

    Stem

    Stem

    Indicatio

    ns:b

    lood

    stasissymptom

    [10]

    Indicatio

    ns:d

    iarrhe

    a,im

    potence[14]

    ADigestive

    disorders

    Reprod

    uctive

    system

    disorders

    22Iridaceae

    Crocus

    sativus

    L.藏红花*

    Stigma

    Stigma

    Indicatio

    ns:amen

    orrhea,abd

    ominal

    mass,andpalpitatio

    ndu

    eto

    frigh

    t[10]

    Indicatio

    ns:p

    neum

    oniaandliver

    diseases

    [13]

    ACirculatory

    system

    disorders

    Digestive

    disorders

    23Lamiaceae

    Lagopsis

    supine(Steph

    .ex

    Willd.)Ikon

    n.-Gal.

    exKn

    orr

    夏至草

    Who

    leplant

    Flow

    er,

    aerialp

    arts

    andseed

    Toregu

    late

    men

    struationby

    nourishing

    bloo

    d[9]

    Indicatio

    ns:b

    lood

    diseases

    dueto

    heat,b

    lood

    shot

    eyes

    ofne

    buladu

    eto

    bloo

    dhe

    at,p

    arasito

    sis[15]

    CNervous,

    reprod

    uctive

    system

    disorders

    Immun

    esystem

    ailm

    ents

    24Lamiaceae

    Leon

    urus

    japonicusThun

    b.(

    Leon

    urus

    japo

    nicas

    Hou

    tt.)*

    益母草*

    Who

    leplant,fru

    itsFruits,seed

    andaerial

    parts

    Indicatio

    ns:m

    enstrualdisorders,

    dysm

    enorrhea,amen

    orrhea,

    incessantdripping

    oflochia;ede

    ma

    andoliguriasuch

    ased

    emain

    acute

    neph

    ritis[10]

    Indicatio

    ns:

    Fruits:eno

    xenia,am

    enorrhea,

    dysm

    enorrhea,m

    assesform

    ationin

    thestom

    ach,conjun

    ctivalcong

    estio

    ned

    emapain,eye

    inflammation,

    cornealo

    pacity,and

    hype

    rten

    sion

    [8];

    aerialp

    arts;

    Seed

    :blood

    diseases

    dueto

    heat,

    bloo

    dsho

    teyes

    ofne

    buladu

    eto

    bloo

    dhe

    at,and

    parasitosis[15]

    CReprod

    uctive

    andurinary

    system

    disorders

    Reprod

    uctive

    andcirculatory

    system

    disorders

    25Lamiaceae

    Leon

    urus

    sibiricus

    L.细叶益

    母草

    Who

    leplant

    Aerialp

    arts

    andseed

    Indicatio

    ns:m

    enoxen

    ia,amen

    orrhea,

    postpartum

    cong

    estio

    nabdo

    minal

    pain,nep

    hritised

    ema,dysuria,and

    hematuria[10]

    Indicatio

    ns:b

    lood

    diseases

    dueto

    heat,b

    lood

    shot

    eyes

    ofne

    buladu

    eto

    bloo

    dhe

    at,and

    parasitosis[15]

    CReprod

    uctive

    andurinary

    system

    disorders

    Immun

    esystem

    ailm

    ents

    26Fabaceae

    Acaciacatechu

    (L.f.)W

    illd*

    儿茶*

    Twig

    Woo

    dIndicatio

    ns:festerin

    gwou

    nddifficult

    tohe

    alup

    ,skindiseases

    with

    watery

    discharge,ulcersin

    themou

    th,and

    traumaticinjury

    with

    pain

    and

    bleeding

    [10]

    Indicatio

    ns:cou

    ghandthirst,external

    useforskin

    diseases

    with

    watery

    discharge,ulcerativeging

    ivitis,and

    ulcersin

    themou

    thandhe

    morrhoid

    [8]

    AIm

    mun

    e,locomotor

    system

    ailm

    ents

    Respiratory

    andim

    mun

    esystem

    ailm

    ents

    27Legu

    minosae

    Cassiatora

    Linn

    .决明*

    Seed

    Seed

    Indicatio

    ns:headacheandvertigo,

    eyediseases,and

    constip

    ation[10]

    Indicatio

    ns:skindiseases

    and

    epilepsy[15]

    AFive

    sense

    organs

    related

    ailm

    ents

    Immun

    esystem

    ailm

    ents

    28Fabaceae

    Pterocarpus

    indicusWilld.

    紫檀

    Heartwoo

    dHeartwoo

    dIndicatio

    ns:furun

    cleandsw

    ollen[20]

    Indicatio

    ns:hypertension,

    pneumon

    ia,and

    heartdiseases

    [7]

    AIm

    mun

    esystem

    ailm

    ents

    Immun

    esystem

    ailm

    entsand

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 12 of 27

  • Table

    4Inform

    ationon

    classIV

    (Con

    tinued)

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreated

    inTM

    respiratory

    disorders

    29Fabaceae

    Abrusprecatorius

    L相思子

    Roots,

    rattan

    cane

    ,leaf,

    andseed

    Seed

    Roots,rattan:sorethroat,and

    hepatitis.

    Leaf:b

    ronchitis,seedexternalusefor

    boils,and

    eczema[9]

    Indicatio

    ns:g

    ynecop

    athy

    and

    gallbladd

    ermasses[15]

    CRespiratory

    anim

    mun

    esystem

    ailm

    ents

    Reprod

    uctive

    system

    disorders

    30Liliaceae

    Fritillaria

    cirrho

    saD.Don

    *川贝母*

    Bulb

    Bulb

    Indicatio

    ns:d

    rycoug

    hdu

    eto

    heat

    inthelung

    andcoug

    hwith

    bloo

    dysputum

    inconsum

    ptivediseases

    [10]

    Indicatio

    ns:yellow

    fluid

    diseases,

    men

    ometrorrhagia,andtrachitis

    [13]

    ARespiratory

    disorders

    Locomotor

    and

    respiratory

    disorders

    31Loganiaceae

    Strychno

    snu

    x-vomicaLinn

    .*马钱*

    Seed

    Seed

    Indicatio

    ns:p

    rotractedarthritis,

    rheumatoidarthralgia;num

    bness

    andparalysis;sequ

    elaof

    poliomyelitis;traum

    aticinjury;b

    oils

    andsores[10]

    Indicatio

    ns:rlung

    diseases,b

    lood

    heat

    diseases,stomachcram

    pstoxicosis[15]

    ANervous

    system

    ailm

    ents,

    locomotor,

    immun

    esystem

    ailm

    ents

    Circulatory

    system

    disorders

    32Malvaceae

    Abelmoschus

    moschatus

    Med

    ic黄葵

    Roots,leaf,

    andflower

    Leaf,

    flower,and

    seed

    Indicatio

    ns:

    Root:highfever,coug

    hdu

    eto

    lung

    heat,p

    ostpartum

    milk

    atresia,stoo

    lconstip

    ate,dysentery,andurinary

    calculi.

    Leaf:top

    icalfester

    swelling,

    felon,

    bone

    fracture.

    Flow

    er:b

    urns

    andscalds

    [9]

    Indicatio

    ns:yellow

    fluid

    diseases,

    derm

    atosis,p

    arasito

    sis,anditching

    [16]

    ERespiratory

    and

    dige

    stive,

    urinarysystem

    disorders

    Immun

    esystem

    ailm

    ents

    33Men

    ispe

    rmaceae

    Tino

    sporasin

    ensis

    (Lou

    r.)Merr.

    中华青

    牛胆

    Rattan

    Stem

    Tosoothe

    tend

    onsandactivate

    collaterals;d

    ispe

    lwindandrelieve

    pain

    [10]

    Indicatio

    ns:lun

    gdisease,rheumatoid

    arthritis[7]

    DRespiratory,

    dige

    stive

    disorders

    Digestive,

    immun

    esystem

    ailm

    ents

    34Oleaceae

    Fraxinus

    stylosa

    Ling

    elsh.

    宿柱白

    蜡树

    Bark

    Bark

    Indicatio

    ns:d

    iarrhe

    a,leukorrhea,and

    conjun

    ctivecong

    estio

    nwith

    swelling

    andpain

    [10]

    Indicatio

    ns:fracture,hype

    rosteo

    geny,

    andosteom

    yelitis[14]

    AUrin

    arysystem

    disorders

    Locomotor

    system

    ailm

    ents

    35Orchidaceae

    Dendrobium

    hookerianu

    mLind

    l.

    金耳石

    斛Stem

    Aerialp

    art

    Indicatio

    ns:thirst,hiccup

    ,and

    lassitu

    dein

    theloin

    andlegs

    [10]

    Indicatio

    ns:ind

    igestio

    n,gastric

    ulcer,

    sore

    throat,and

    hemorrhoids

    [12]

    BDigestive

    disorders

    Digestive

    disorders

    36Ph

    ytolaccaceae

    Phytolacca

    acinosaRo

    xb.*

    商陆*

    Root

    Root

    Indicatio

    ns:anasarcawith

    oliguria

    andconstip

    ation;externalusefor

    carbun

    cles

    andsores[10]

    Indicatio

    ns:feb

    riledisease,ed

    ema,

    disten

    sion

    ,dysuria;externalu

    sefor

    carbun

    cles,b

    oils,swelling,

    and

    toxicity

    [15]

    ADigestive,

    urinarysystem

    disorders

    Digestive,

    urinarysystem

    disorders

    37Po

    lypo

    diaceae

    Pyrrosialingua

    (Thu

    nb.)Farw

    .*石韦*

    Who

    leplant

    Who

    leplant

    Indicatio

    ns:urin

    aryinfectionand

    urination;spittingof

    bloo

    d,ep

    istaxis,

    hematuria,and

    abno

    rmaluterine

    bleeding

    ;and

    coug

    handasthma

    dueto

    heat

    inthelung

    [10]

    Indicatio

    ns:p

    usandsoresin

    the

    chest,coug

    hdu

    eto

    heat

    inthelung

    .Laryng

    opharyng

    itis,spinalcord

    cavity

    disease,traumaticinjury,traum

    ahe

    morrhage,seminalem

    ission

    in

    AUrin

    aryand

    respiratory

    disorders

    Respiratory,

    locomotor,

    and

    reprod

    uctive

    system

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 13 of 27

  • Table

    4Inform

    ationon

    classIV

    (Con

    tinued)

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreated

    inTM

    kidn

    eyde

    ficiencysynd

    rome,

    neph

    ritis,ede

    ma,andurinarytract

    infections

    [16]

    disorders

    38Pteriidae

    Pinctada

    martensii(

    Dun

    ker)*

    马氏珍

    珠贝*

    Pearland

    dryshell

    Pearland

    dryshell

    Indicatio

    ns:

    Pearl:palpitatio

    nandinsomnia;

    convulsion

    ,epilepsy;ne

    bula;skin

    ulceratio

    nsdifficultto

    heal.

    Nacre:headache,dizziness,

    fidge

    tingn

    ess,andinsomnia;

    inflammationof

    theeyes

    dueto

    heat

    intheliver;and

    blurredvision

    inde

    ficiencyof

    theliver

    [10]

    Indicatio

    ns:com

    motio

    cerebri,he

    adinjury,w

    hite

    veinsdisease,nu

    mbn

    ess

    andpain

    inarthritis,and

    nosotoxicosis[14]

    ANervous

    system

    ailm

    ents

    Nervous

    system

    ailm

    ents

    39Lythraceae

    Punica

    gran

    atum

    L.*

    石榴

    Root,stem,

    bark,

    flower,

    leaf,fruit

    Seed

    Indicatio

    ns:p

    rotracteddiarrhea,

    chronicdysentery;he

    matoche

    zia,

    prolapse

    oftherectum

    ;abn

    ormal

    uterinebleeding

    ,leukorrhagia;and

    intestinalparasitosiswith

    abdo

    minal

    pain

    [10]

    Indicatio

    ns:ano

    rexia,dyspep

    sia,and

    aching

    ofkidn

    eyandloinsdu

    eto

    cold

    inthestom

    ach[14]

    DDigestiveand

    reprod

    uctive

    system

    disorders

    Digestive

    disorders

    40Ranu

    nculaceae

    Paeoniaveitchii

    Lynch*

    川赤芍*

    Roots

    Roots

    Indicatio

    ns:m

    aculationin

    epidem

    icdiseases;spittingof

    bloo

    d,ep

    istaxis;

    inflammationof

    theeye;pain

    inthe

    chest;am

    enorrhea,d

    ysmen

    orrhea;

    massform

    ationin

    theabdo

    men

    ;traumaticinjuries;andbo

    ilsand

    sores[10]

    Indicatio

    ns:carbu

    ncles,fever.

    Flow

    er:d

    ermatosis,d

    ermatitis[16]

    BIm

    mun

    esystem

    ailm

    entsand

    reprod

    uctive

    andlocomotor

    system

    ailm

    ents

    Immun

    esystem

    ailm

    ents

    41Santalaceae

    Santalum

    album

    L.*

    檀香*

    Heartwoo

    dHeartwoo

    dIndicatio

    ns:p

    ectoraland

    abdo

    minal

    pain

    dueto

    stagnatio

    nof

    qiwith

    cold;epigastric

    pain,lossof

    appe

    tite;

    andangina

    pectorisin

    heartdisease

    [10]

    Indicatio

    ns:p

    neum

    oniaandlung

    abscess[16]

    ADigestiveand

    circulatory

    system

    disorders

    Circulatory

    and

    respiratory

    system

    disorders

    42Sapind

    aceae

    Sapind

    usmukorossiGaertn.

    无患子

    Root,fruit

    Seed

    Toremovehe

    atandph

    legm

    ,che

    ckdiarrhea

    andbloo

    dstasis[9]

    Indicatio

    ns:d

    iphthe

    ria,vesicula

    seminalisdisease,strang

    uriawith

    turbid

    discharge,andfre

    quen

    turination[7]

    DRespiratory

    disorders

    Respiratory

    andurinary

    system

    disorders

    43Saxifragaceae

    Bergenia

    purpurascens

    (Hoo

    k.f.et

    Thom

    s.)Engl

    *

    岩白菜*

    Rhizom

    eRh

    izom

    e,who

    leplant

    Toremovetoxiche

    at,arrest

    bleeding

    ,and

    regu

    late

    men

    struation

    [9]

    Epidem

    icfebrile

    diseases,liver

    and

    lung

    heat

    diseases,and

    dysentery

    [15]

    ACirculatory

    system

    disorders

    Respiratory

    anddige

    stive

    disorders

    44Styracaceae

    Styrax

    benzoin

    Dryand.

    *安息香*

    Resin

    Resin

    Indicatio

    ns:lossof

    consciou

    snessin

    stroke

    andattack

    ofno

    xiou

    sfactors,

    syncop

    edu

    eto

    violen

    texcitemen

    tor

    postpartum

    anem

    ia;p

    ainin

    the

    chestandep

    igastrium;infantile

    convulsion

    [10]

    Indicatio

    ns:rlung

    diseases,

    subcutaneo

    usulcer,andbo

    ils[15]

    ANervous

    system

    ailm

    entsand

    circulatory

    system

    disorders

    Digestive,

    immun

    esystem

    ailm

    ents

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 14 of 27

  • Table

    4Inform

    ationon

    classIV

    (Con

    tinued)

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreated

    inTM

    45ApiaceaeA

    piaceae

    Angelicasin

    ensis

    (Oliv.)Diels.*

    当归*

    Roots

    Roots

    Indicatio

    ns:ane

    miawith

    dizziness

    andpalpitatio

    n;men

    strualdisorders,

    amen

    orrhea,d

    ysmen

    orrhea;

    constip

    ation;rheumaticarthralgia;

    traumaticinjuries;carbun

    cles,b

    oils,

    andsores.RadixAng

    elicae

    Sine

    nsis

    (stri-b

    aked

    with

    wine)

    amen

    orrhea,

    dysm

    enorrhea,rhe

    umatic,arthralgia,

    andtraumaticinjuries[10]

    Indicatio

    ns:chron

    icfebrile

    diseases,

    cardiopyretic

    disease,toxicosis,and

    complicationof

    badkan

    diseases

    and

    rlung

    diseases

    [15]

    AReprod

    uctive,

    dige

    stive,

    immun

    e,and

    locomotor

    system

    ailm

    ents

    Digestiveand

    respiratory

    disorders

    46ApiaceaeA

    piaceae

    Heracleum

    cand

    ican

    sWall.

    exDC..

    白亮独

    活Ro

    ots

    Roots

    Indicatio

    ns:rhe

    umatism

    andpain

    inthewaistandknee

    [10]

    Indicatio

    ns:b

    oils,sores,and

    leprosy

    [15]

    AIm

    mun

    esystem

    ailm

    ents

    Immun

    esystem

    ailm

    ents

    47ApiaceaeA

    piaceae

    Notopterygium

    forbesiide

    Boiss.

    宽叶羌

    活Ro

    otsand

    rhizom

    eRo

    otsand

    rhizom

    eIndicatio

    ns:com

    mon

    cold

    caused

    byexterio

    rwind-cold,rhe

    umatism

    numbn

    ess,urticaria,and

    itching

    [10]

    Indicatio

    ns:p

    lagu

    e,greenflyand

    pinw

    orm,hem

    orrhagedisease,

    constip

    ation,andleprosy[14]

    ARespiratory

    and

    immun

    esystem

    ailm

    ents

    Immun

    esystem

    ailm

    entsand

    circulatory

    system

    disorders

    48Apiaceae

    Notopterygium

    incisum

    Ting

    exH.T.C

    hang

    *

    羌活*

    Rootsand

    rhizom

    eRo

    otsand

    rhizom

    eIndicatio

    ns:headachein

    common

    cold,rhe

    umaticarthralgia,and

    aching

    oftheback

    andshou

    lders

    [10]

    Indicatio

    ns:lep

    rosy,h

    eadache,

    laryng

    opathy,rhe

    umaticarthralgia,

    andep

    idem

    icdiseaseor

    cholera[15]

    ARespiratory

    and

    immun

    esystem

    ailm

    ents

    Immun

    esystem

    ailm

    entsand

    circulatory

    system

    disorders

    49Union

    idae

    Cristariaplicata

    (Leach)*

    褶纹冠

    蚌*

    Pearland

    dryshell

    Pearland

    dryshell

    Indicatio

    ns:p

    earl:palpitatio

    nand

    insomnia;convulsion

    ,epilepsy;

    nebu

    la;skinulceratio

    nsdifficultto

    heal.N

    acre:headache,dizziness,

    fidge

    tingn

    essandinsomnia;

    inflammationof

    theeyes

    dueto

    heat

    intheliver;and

    blurredvision

    inde

    ficiencyof

    theliver

    [10]

    Indicatio

    ns:com

    motio

    cerebri,he

    adinjury,w

    hite

    veinsdisease,nu

    mbn

    ess

    andpain

    inarthritis,n

    osotoxicosis

    [14]

    ANervous

    system

    ailm

    ents

    Nervous

    system

    ailm

    ents

    50Union

    idae

    Hyriopsis

    cumingii(Lea).*

    三角帆

    蚌*

    Pearland

    dryshell

    Pearland

    dryshell

    Indicatio

    ns:p

    earl:palpitatio

    nand

    insomnia;convulsion

    ,epilepsy;

    nebu

    la;skinulceratio

    nsdifficultto

    heal.N

    acre:headache,dizziness,

    fidge

    tingn

    essandinsomnia;

    inflammationof

    theeyes

    dueto

    heat

    intheliver;and

    blurredvision

    inde

    ficiencyof

    theliver

    [10]

    Indicatio

    ns:com

    motio

    cerebri,he

    adinjury,w

    hite

    veinsdisease,nu

    mbn

    ess

    andpain

    inarthritis,and

    nosotoxicosis[14]

    ANervous

    system

    ailm

    ents

    Nervous

    system

    ailm

    ents

    51Valerianaceae

    Nardostachys

    chinensis

    Batal.*

    甘松*

    Rootsand

    rhizom

    eRo

    otsand

    rhizom

    eIndicatio

    ns:epigastric

    andabdo

    minal

    disten

    sion

    with

    anorexiaand

    vomiting

    ;and

    externalusefor

    toothacheandsw

    ollenfeet

    [10]

    Indicatio

    ns:accum

    ulationof

    damp-

    cold

    inthespleen

    andthestom

    ach

    manifested

    byep

    igastricdisten

    tion

    andpain,externalu

    seforulcerative

    ging

    ivitis,andde

    ntalcariesand

    ADigestive

    disorders

    Digestive

    disorders

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 15 of 27

  • Table

    4Inform

    ationon

    classIV

    (Con

    tinued)

    No.

    Family

    Scientificname

    Chine

    sename

    Partsused

    inTC

    MPartsused

    inTM

    Usesin

    TCM

    Usesin

    TMParts

    used

    Disease

    grou

    pstreatedin

    TCM

    Disease

    grou

    pstreated

    inTM

    swollenfeet

    [8]

    52Valerianaceae

    Nardostachys

    jataman

    si(D.

    Don

    )DC.

    匙叶甘

    松Ro

    otsand

    rhizom

    eRo

    otsand

    rhizom

    eTo

    regu

    late

    theflow

    ofqi

    andrelieve

    pain

    andto

    invigo

    rate

    thespleen

    functio

    n[10]

    Toremovetoxiche

    at,d

    ispe

    lcold

    andelim

    inatesw

    elling[14]

    ADigestive

    disorders

    Immun

    esystem

    ailm

    ents

    53Vitaceae

    Vitis

    vinifera

    L.葡萄

    Fruitsand

    roots

    Fruits

    Indicatio

    ns:m

    easles,d

    ysuria,

    rheumatism,and

    fracture[9]

    Indicatio

    ns:lun

    gdiseases

    [15]

    CRespiratory,

    urinary,and

    locomotor

    system

    ailm

    ents

    Respiratory

    disorders

    54Zing

    iberaceae

    Curcum

    along

    aL.*

    姜黄*

    Rhizom

    eRh

    izom

    eIndicatio

    ns:p

    ricking

    pain

    inthechest

    andhypo

    chon

    driacregion

    s,men

    orrhea,m

    assform

    ationin

    the

    abdo

    men

    ,rhe

    umaticpain

    ofthe

    shou

    ldersandarms,andtraumatic

    swellingandpain

    [10]

    Indicatio

    ns:ulcerationand

    hemorrhoids,sores,and

    epidem

    icdiseases

    [14]

    AReprod

    uctive,

    immun

    e,and

    locomotor

    system

    ailm

    ents

    Immun

    esystem

    ailm

    ents

    55Zygo

    phyllaceae

    Tribulus

    terrestris

    L.*

    蒺藜*

    Fruits,

    who

    leplant

    Fruits

    Indicatio

    ns:headacheanddizziness,

    disten

    ding

    pain

    inthe

    hypo

    chon

    drium;cessatio

    nof

    lactation,mastitis,and

    bloo

    dsho

    teyes

    ofne

    bula;and

    urticariawith

    itching

    [10]

    Indicatio

    ns:headache,itching

    ,disten

    ding

    pain

    inthe

    hypo

    chon

    drium;reverse

    ofqi,

    inflammationof

    eyes,corne

    alop

    acity,m

    assesform

    ationin

    the

    abdo

    men

    ,and

    cessationof

    lactation

    [8]

    ADigestive,

    reprod

    uctive

    andim

    mun

    esystem

    ailm

    ents

    Urin

    arysystem

    disorders

    56–

    Calam

    ina

    炉甘石

    Natural

    mineral

    Natural

    mineral

    Indicatio

    ns:eye

    diseases

    andpruritu

    s[10]

    Indicatio

    ns:skindiseases

    [12]

    AIm

    mun

    esystem

    ailm

    ents

    Digestive

    disorders

    57–

    Realgar

    雄黄*

    Natural

    mineral

    Natural

    mineral

    Indicatio

    ns:carbu

    ncle,furun

    culosis,

    snakebite,epilepsy,andmalaria[10]

    Indicatio

    ns:g

    alland

    diph

    theria[13]

    AIm

    mun

    esystem

    ailm

    entsand

    dige

    stive

    disorders

    Immun

    esystem

    ailm

    ents

    58–

    Actinolite

    asbe

    stos.

    (阳起

    石)石

    棉Natural

    mineral

    Natural

    mineral

    Indicatio

    ns:p

    ainin

    waistandknee

    andim

    potence[20]

    Indicatio

    ns:ten

    doninjury,cou

    gh,

    swollensore

    throat,and

    dysuria

    [14]

    AReprod

    uctive

    system

    disorders

    Locomotor

    and

    respiratory

    disorders

    59–

    Calcitum*

    寒水石*

    Sulfate

    minerals

    Sulfate

    minerals

    Indicatio

    ns:fever

    andpo

    lydipsia,

    swollensore

    throat,ulcersin

    the

    mou

    thon

    thetong

    ue,too

    thache

    ,andexternaluseforbu

    rnsandscalds

    [9]

    Indicatio

    ns:various

    gastropathyand

    gastric

    ulcerdu

    eto

    dyspep

    sia,

    massesin

    theabdo

    men

    ,ede

    ma,

    diarrhea,and

    trauma[14]

    ARespiratory

    disorders

    Digestive

    disorders

    60–

    Cinnabaris*

    朱砂*

    Thesulfide

    mineralsof

    cinn

    abar

    Thesulfide

    mineralsof

    cinn

    abar

    Indicatio

    ns:p

    alpitatio

    n,insomniaand

    dream-disturbed

    sleep;

    epilepsy,

    mania,and

    infantile

    convulsion

    ;blurredvision

    ;ulcersin

    themou

    th;

    Indicatio

    ns:p

    usof

    wou

    nds,yellow

    fluid

    diseases,inflammation,and

    bone

    fracture[21]

    ANervous

    system

    ailm

    entsand

    respiratory

    disorders

    Locomotor

    system

    ailm

    ents

    Zhao et al. Journal of Ethnobiology and Ethnomedicine (2019) 15:43 Page 16 of 27

  • Table

    4Inform

    ationon

    classIV

    (Con

    tinued)

    No.

    Family

    Scien