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8Welcome Message

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88Scientific Program

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88Scientific Program

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88Program at a Glance

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88Scientific Program

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88Scientific Program

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88Scientific Program

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88Scientific Program

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88Program at a Glance

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88Scientific Program

xvi June 14-16, 2018 ｜ Grand Hyatt Incheon, Korea

88Scientific Program

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88Scientific Program

xviii June 14-16, 2018 ｜ Grand Hyatt Incheon, Korea

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Plenary Session 1

PS 1-1 Entecavir Plus Pegylated Interferon Alfa-2a and Sequential HBV Vaccination Increases the Chance of HBsAg-Seroclearance: A Results from Randomized Controlled E+VIP Trial ································································································································· 2Jeong-Hoon Lee, Sungwon Chung, Min Suk Kim, Sung Woong Kim, Jun Sik Yoon, Young Chang, Yun Bin Lee, Eun Ju Cho, Su Jong Yu, Jung-Hwan Yoon, Yoon Jun Kim

PS 1-2 Efficacy of Sorafenib Monotherapy versus Transarterial Chemoembolization (TACE)-Sorafenib Sequential Therapy in Patients with Extrahepatic Metastasis - An Interim Analysis of Randomized Controlled Trial ·························································································· 2Hyung Joon Yim, Sang Jun Suh, Young Kul Jung, Sung-Bum Cho, Woo Jin Chung, Young Seok Kim, Si-Hyun Bae, Jun Young Park

PS 1-3 Necessity for the Elimination of Total Necrosis from Hepatocellular Carcinoma Staging after Liver Transplantation ···································· 3Deok Gie Kim, Yoon Bin Jung, Jae Geun Lee, Dong Jin Joo, Soon Il Kim, Myoung Soo Kim

PS 1-4 Transarterial Chemoembolization plus External Beam Radiotherapy Improves Survival of Patients with Hepatocellular Carcinoma Showing Macroscopic Vascular Invasion Compared with Sorafenib: A Randomized Trial ·········································································· 3Sang Min Yoon, Baek-Yeol Ryoo, So Jung Lee, Jong Hoon Kim, Ji Hoon Shin, Jihyun An, Han Chu Lee, Young-Suk Lim

Plenary Session 2

PS 2-1 A Prospective, Open-Label, Dose-Escalation, Single-Center, Phase 1 Study for gc1102, a Recombinant Human Immunoglobulin for Chronic Hepatitis B Patients ····························································································································································· 6Hye Won Lee, Jun Yong Park, Taegon Hong, Min Soo Park, Sang Hoon Ahn

PS 2-2 Sorafenib with versus without Concurrent Conventional Transarterial Chemoembolization (cTACE) in Patients with Advanced Hepatocellular Carcinoma (HCC): Results from a Multicenter, Open-Label, Randomized, Controlled Phase III STAH Trial ···························· 6Joong-Won Park, Yoon Jun Kim, Do Young Kim, Si Hyun Bae, Seung Woon Paik, Youn-Jae Lee, Donghyeon Lee, Han Chu Lee, Sang Young Han, Jae Youn Cheong, Oh Sang Kwon, Jong Eun Yeon, Bo Hyun Kim, Jae-Seok Hwang

PS 2-3 DNA Vaccine Encoding HCV Nonstructural Proteins Enhances Virus-Specific Cellular Immune Responses in Patients with Chronic Hepatitis C ···· 7Ji Won Han, Pil Soo Sung, Seon-Hui Hong, Hyojin Lee, Moonsup Jeong, Su-Hyung Park, Jian Yan, Amir Khan, Joel N. Maslow, David B. Weiner, Jeong Heo, Sang Hoon Ahn, Eui-Cheol Shin

PS 2-4 Feasibility of Total Laparoscopic Living Donor Right Hepatectomy Compared with Open Surgery: Comprehensive Review of 100 Laparoscopic Cases ·············································································································································································· 7Jinsoo Rhu, Gyu Seong Choi, Jong Man Kim, Jae-Won Joh, Choon Hyuck David Kwon

Free Paper Session

1. HBV

O-001 Prediction of Histologic Immune-Tolerant Phase Chronic Hepatitis B from HBeAg-Positive with Low ALT Level Paitents ··························· 10Jeong-Ju Yoo, Sang Gyune Kim, Young Seok Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Baek Gyu Jun, Young Don Kim, Gab Jin Cheon

O-002 Adverse Outcomes of HBeAg-Negative Chronic Hepatitis B Patients with High Viral Load and No Significant ALT Elevation ····················· 10Gwang Hyeon Choi, Gi-Ae Kim, Jihyun An, Jonggi Choi, Seungbong Han, Young-Suk Lim

O-003 Cost-Effectiveness of Anti-Viral Treatment in Patients with Immune-Tolerant Phase Chronic Hepatitis B ················································· 11Hye-Lin Kim, Gi-Ae Kim, Jae-A Park, Hye-Rim Kang, Eui-Kyung Lee, Young-Suk Lim

O-004 Cost-Effectiveness Antiviral Therapy Indication for the Prevention of Hepatitis B Virus Related Hepatocellular Carcinoma ························· 11Dong-Hyun Sinn, Beom Kyung Kim, Sung Eun Kim, Ji Hoon Kim, Moon Seok Choi

O-005 A Multicenter Randomized Trial Investigating the Antiviral Efficacy of Tenofovir Switch Therapy for Lamivudine-Resistant Chronic Hepatitis B Patients with Complete Virological Response to Lamivudine plus Adefovir Therapy: Interim Analysis of 96 Weeks Foll ············ 12SungKeun Kim, Hee Yeon Kim, Chang Wook Kim, Jin Ah Kim, Mi Ju Cheon, Chan Ran You, Sang Wook Choi, Do Seon Song, U Im Chang, Jin Mo Yang, Sung Won Lee, Hae Lim Lee, Nam Ik Han, Myeong Jun Song, Hyung Jum Yim, Sang Jun Suh, Young Kul Jung, Joo Ho Lee, Hana Park

O-006 Tenofovir-Based Combination Therapy or Monotherapy for Multi-Drug Resistant Chronic Hepatitis B; Five Year Follow-Up Data of Multicenter Prospective Cohort Study (Final Results) ····························································································································· 12Sang Jun Suh, Hyung Joon Yim, Young Kul Jung, Seong Gyu Hwang, Hana Park, Yeon Seok Seo, Soon Ho Um, Sae Hwan Lee, Young Seok Kim, Jae Young Jang, In Hee Kim, Hyoung Su Kim, Ji Hoon Kim, Young Sun Lee, Eileen L. Yoon, Myeong Jun Song, Jun Yong Park

O-007 Entecavir Improves Liver Function and Fibrosis in Hepatitis B Virus‐Associated Cirrhosis: A 6 Years-Multicenter Study ······························· 13Seung Kak Shin, Oh Sang Kwon, Jeong Han Kim, Chan Uk Lee, Jong Eun Yeon, Sang Jun Suh, Young Kul Jung, Hyung Joon Yim, Duck Joo Choi, Yun Soo Kim, Ju Hyun Kim

O-008 A Single Substitution Mutation in Viral Polymerase of Hepatitis B Virus Confers Antiviral Resistance to Tenofovir Disoproxil Fumarate ······ 13Seungtaek Kim, Do Young Kim, Hye Jung Park, Hye Won Lee, Bora Jin, Kwang-Hyub Han, Sang Hoon Ahn

O-009 Projection of Health Outcomes Using Tenofovir Alafenamide (TAF) for the Management of Chronic Hepatitis B (CHB) in Korea ·············· 14Moon Seok Choi, Ali Tafazzoli, Catherine Saint-Laurent Thibault, Do Young Kim

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O-010 An Observational Study about Long-Term Renal Outcome in Chronic Hepatitis B Patients Treated with Tenofovir Disoproxil Fumarate in Korea ·············································································································································································· 14Tae Seop Lim, Hye Won Lee, Mi Young Jeon, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Kwang-Hyub Han, Sang Hoon Ahn

O-011 Renal Safety of Entecavir and Tenofovir in Patients with Treatment-NaïVe Chronic Hepatitis B Virus Infection in Real Life Setting: A Multicenter, Retrospective Cohort Study·············································································································································· 15Jae Yoon Jeong, Dae Won Jun, Sung Eun Kim, Eileen L. Yoon, Jae-Jun Shim, Sang Bong Ahn, Yong Kyun Cho, Soung Won Jeong, Hyoung Su Kim

O-012 Prospective, Randomized Safety Assessment of Long-Term Therapy With Entecavir or Other Nucleos(t)ide Analogues in Korean Patients with Chronic HBV Infection ···················································································································································· 15Changhyeong Lee, Joung-Il Lee, Kwang-Hyub Han, Sang-Young Han, Jeong Heo, Kwan Sik Lee, Dong Joon Kim, June Sung Lee, Kyungha Yu, Alexandra Thiry, Elizabeth Cooney

2. Cirrhosis

O-013 Multicenter Validation of the Baveno VI Criteria for Screening High-Risk Varices in Patients with Compensated Advanced Chronic Liver Disease ······························································································································································································ 16Han Ah Lee, Seung Up Kim, Hyung Joon Yim, Yeon Seok Seo, Young-Sun Lee, Sang Jun Suh, Ki Tae Suk, Soung Won Jeong, Young Kul Jung, Moon Young Kim, Ji Hoon Kim, Sang Gyune Kim, The Korean Transient Elastography Study Group

O-014 Screening of Esophageal Varices: Performance of Baveno Criteria with Shear-Wave Elastography in Patients with Compensated Advanced Chronic Liver Disease ·························································································································································· 17Seong Hee Kang, Seung Kook Cho, Seungheon Kang, Shin Myung Kang, Hohyun Park, Soon Koo Baik, Moon Young Kim

O-015 What Are the Risk Factors and Rescue Treatments for Endoscopic Variceal Ligation Failure? ·································································· 17Dong Hyun Kim, Eunae Cho, Chung Hwan Jun, Dong Jun Son, Myeon Jae Lee, Chang Hwan Park, Sung Bum Cho, Seon Young Park, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew

O-016 Significant Increase of Portal Pressure in Cirrhotic Patients with Gastric Varices after Plug-Assisted Retrograde Transvenous Obliteration (PARTO) and Its Clinical Significances: Single Tertiary Center Experience ································································································ 18Jae Woo Park, Jeong-Ju Yoo, Sang Gyune Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Boo Sung Kim, Jae Myung Lee, Jong Joon Shim, Young Don Kim, Gab Jin Cheon, Baek Gyu Jun, Young Seok Kim

O-017 Validation of Korean Stroop Test in the Screening of Minimal Hepatic Encephalopathy ·········································································· 18Eileen L. Yoon, Dae Won Jun, Jae Yoon Jeong, Tae Yeob Kim, Do Seon Song, Sang Bong Ahn, Hee Yeon Kim, Young Kul Jung, Myeong Jun Song, Sung Eun Kim, Hyoung Su Kim, Soung Won Jeong, Sang Gyune Kim, Tae Hee Lee, Yong Kyun Cho

O-018 The Role of Spleen Volume in Predicting Portal Hypertension in Patients with Cirrhosis ·········································································· 19Hae Won Yoo, Sang Gyune Kim, Young Seok Kim, JeongJu Yoo, Jae Woo Park, Yong seok Lim, Jae myeong Lee, Gab Jin Cheon, Jae Young Jang, Young Don Kim, Soung Won Jeong, Sae Hwan Lee, BaekGyu Jun, Hong Soo Kim, Boo Sung Kim

O-019 Prediction of Acute Kidney Injury and Mortality in Patients with Decompensated Cirrhosis with Serum Cystatin C and Urine N-Acetyl-β-D-Glucosaminidase ···························································································································································· 19Tae Hyung Kim, Yeon Seok Seo, Yoo Ra Lee, Han Ah Lee, Sun Young Yim, Young Sun Lee, Sang Jun Suh, Young Kul Jung, Ji Hoon Kim, Hyunggin An, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun, Soon Ho Um

O-020 The Role of Kidney Biomarkers in Cirrhotic Patients with Acute Kidney Injury: Interim-Analysis of Multicenter, Prospective Cohort Study ·· 20Jeong-Ju Yoo, Jung Hyun Kwon, Young Seok Kim, Soon Woo Nam, Ji Won Park, Hee Yeon Kim, Chang Wook Kim, Seung Kak Shin, Young Eun Chon, Eun-Sun Jang, Sook-Hyang Jeong, Jin Woo Lee, Do Seon Song, Jin Mo Yang, Sung Won Lee, Hae Lim Lee, Young Kul Jung, Hyung Joon Yim, Sang Gyune Kim, Ju Hyun Kim

O-021 The Prevalence and Clinical Course of Adrenal Insufficiency in Patients with Cirrhosis ············································································ 20Mi Young Jeon, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han

O-022 The Cut-Off Value of Transient Elastography to Hepatic Venous Pressure Gradient for Alcoholic and Viral Cirrhosis in Korean Patients ···· 21Se Ri Ryu, Seong Hee Kang, Jeong-Ju Yoo, Soung Won Jeong, Moon Young Kim, Sang Gyune Kim, Jae Young Jang, Young Seok Kim, Soon Koo Baik, Yong Jae Kim, Su Yeon Park

O-023 Influence of Previous Acute Decompensation and Organ Failure on the Long-Term Prognosis in Cirrhotic Patients with Decompensation 21Do Seon Song, Tae Yeob Kim, Eileen L. Yoon, Jin Mo Yang, Hee Yeon Kim, Chang Wook Kim, Young Kul Jung, Hyung Joon Yim, Soung Won Jeong, Sang Gyune Kim,

Jae Young Jang, Moon Young Kim, Dong Hyun Sinn, Ki Tae Suk, Dong Joon Kim, Korean Acute-on-Chronic Liver Failure (KACLiF) Study Group

O-024 Fibrotic Burden Assessed Using FIB-4 Is Significantly Associated with the Risk of All-Cause Mortality in Patients with Newly Diagnosed Rheumatoid Arthritis ·························································································································································· 22Seung Up Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Yong-Beom Park, Sang-Won Lee

3. NAFLD

O-025 The Impact of Previous Acute Decompensation on Long-term Prognosis According to the Severity of Alcoholic Hepatitis in Cirrhotic Patients ······························································································································································································ 22Eileen L. Yoon, Tae Yeob Kim, Do Seon Song, Jin Mo Yang, Hee Yeon Kim, Chang Wook Kim, Young Kul Jung, Hyung Joon Yim, Soung Won Jeong, Sang Gyune Kim, Jae Young Jang, Moon Young Kim, Dong Hyun Sinn, Ki Tae Suk, Dong Joon Kim, Korean Acute-on-Chronic Liver Failure (KACLiF) Study Group

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O-026 Usefulness of Lactate-Free Asian Pacific Association for the Study of Liver Acute-On-Chronic Liver Failure (ACLF) Research Consortium (AARC)–ACLF Score for Predicting Short-Term Mortality in Patients with Alcoholic Liver Disease ···························································· 23Do Seon Song, Tae Yeob Kim, Hee Yeon Kim1, Eileen L. Yoon, Dong Joon Kim, Korean Acute on Chronic liver failure(KACLiF), Ji Dong Jia, Ashok Kumar Choudhury, Mamun Al Mahtab, Harshad Devarbhavi, Z Duan, Chen Yu, C E Eapen, Ashish Goel, Q Ning, Ke Ma, Y K Chawla, R K Dhiman, Ajay Duseja, Sunil Taneja, S S Hamid, Amna S Butt, Wasim Jafri, S S Tan, Hasmik Ghazinian, Deepak n Amarapurkar, Sombat Treeprasertsuk, G H Lee, S G Lim, Jinhua Hu, L A Lesmana, Cosmas Rinaldi Lesmana, Akash Shukla, Samir Shah, Chetan Kalal, Manoj Sahu, Z Abbas, J D Sollano, Gian Carpio, Fazal Karim, G K Lau, P N Rao, Diana A Payawal, A Kadir, M F Yuen, V G Mohan Prasad, Osamu Yokosuka, Ananta Prasad, Priyanka Jain, Irene Paulson, Shiv K Sarin, AARC working Party

O-027 A Randomized, Double-Blind, Placebo-Controlled Study of a Multispecies Probiotic Mixture in Non-Alcoholic Fatty Liver Disease ············· 24Sang Bong Ahn, Dae Won Jun, Bo-Kyeong Kang, Jae Yoon Jeong, Joo Hyun Sohn, Byoung Kwan Son, Ki Young Lee

O-028 Non-Invasive Evaluation of Liver Fibrosis, Steatosis, and Nonalcoholic Steatohepatitis in Biopsy-Proven NAFLD Patients ···························· 24Young-Sun Lee, Ji Hoon Kim, Hee Sun Park, In Hee Kim, Baek-hui Kim, Chang Hee Lee, Jong Eun Yeon, So Young Kwon, Kwan Soo Byun

O-029 Growth Differentiation Factor 15 Predicts Advanced Fibrosis in Biopsy-Proven Non-Alcoholic Fatty Liver Disease ····································· 25Jimin Han, Bo Kyung Koo, Sung Hee Um, Dong Soo Seo, Sae Kyung Joo, Jeong Mo Bae, Jeong Hwan Park, Mee Soo Chang, Jung Ho Kim, Jieun Lee, Won-Il Jeong, Won Kim

O-030 Validation of Low Alanine Aminotransferase Cutoff for Predicting Hepatocellular Carcinoma and Decompensated Hepatic Events ·········· 25Jin Hwa Park, Dae Won Jun, Eun Jin Kim, Jae Ha Kim

O-031 Prevalence of NAFLD in Asia: A Systematic Review and Meta-Analysis of 195 Studies and 1,753,168 Subjects from 13 Countries ············ 26Jie Li, Biyao Zou, Hideki Fujii, Yee Hui Yeo, Fanpu Ji, Dong Hyun Lee, Yuemin Feng, Xiaoyu Xie, Wanhua Ren, Qiang Zhu, Mindie H. Nguyen

O-032 The Change of Skeletal Muscle Mass Is Associated with Hepatic Steatosis in Non-Alcoholic Fatty Liver Disease ······································· 26Do Seon Song, U Im Chang, Seong Woo Go, Jeong Won Jang, Si Hyun Bae, Seung Kew Yoon, Jin Mo Yang

O-033 Liver Fibrosis Is Associated with Risk for Colorectal Adenoma in Patients with Non-Alcoholic Fatty Liver Disease ······································ 27Min Cheol Kim, Jung Gil Park, Byung Ik Jang, Heon Ju Lee

O-034 Improvement of Nonalcoholic Fatty Liver Disease Reduces the Risk of Incidence of Type 2 Diabetes Mellitus ··········································· 27Hyo Jung Cho, Gil Ho Lee, So Young Yoon, Min Jae Yang, Jae Chul Hwang, Jin Hong Kim, Jae Youn Cheong, Sung Won Cho, Soon Sun Kim

O-035 Noninvasive Prediction of the Presence and Severity of Nonalcoholic Fatty Liver Disease in Korean Patients with Chronic Kidney Disease: A Validation Study ································································································································································· 28Hwi Young Kim, Dong-Ryeol Ryu, Hye Ah Lee, Jin Sil Kim, Jeong Kyong Lee, Tae Hun Kim, Kwon Yoo

O-036 Sarcopenia Is Associated with Advanced Liver Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease ················································ 28Min Kyu Kang, Jung Gil Park, Min Cheol Kim, Heon Ju Lee

4. Liver Cancer

O-037 Late Presentation of Hepatitis B among Patients with Newly Diagnosed Hepatocellular Carcinoma: A National Cohort Study ·················· 29Dong Hyun Sinn, Danbee Kang, Minwoong Kang, Seung Woon Paik, Eliseo Guallar, Juhee Cho, Geum-Youn Gwak

O-038 A MoRAL Score Utilizing Serum Tumor Markers Provides Refined Prognostication of Patients with Hepatocellular Carcinoma after Curative Resection: Data from 662 Consecutive Patients ······················································································································ 29Hyo Young Lee, Yun Bin Lee, Jeong-Hoon Lee, Sungwon Chung, Minseok Albert Kim, Sun Woong Kim, Jun Sik Yoon, Young Chang, Eun Ju Cho, Su Jong Yu, Nam-Joon Yi, Yoon Jun Kim, Kwang-Woon Lee, Kyung-Suk Suh, Jung-Hwan Yoon

O-039 A Phase 1 Study Using Autologous Natural Killer Cells in Patients with HAIC-Hepatocellular Carcinoma ·················································· 30Sung Bum Cho, Chung Hwan Jun, Sung Kyu Choi, Woo Kyun Bae, Je Jung Lee, Yang Jun Kang, Cheol Kyun Cho, Yang Seok Ko

O-040 Adjuvant Cytokine-Induced Killer Cell Immunotherapy for Hepatocellular Carcinoma: A Real-World Experience from Two Large-Volume Centers in Korea ·························································································································································· 31Jun Sik Yoon, Byeong Geun Song, Jeong-Hoon Lee, Hyo Young Lee, Sun Woong Kim, Young Chang, Eun Ju Cho, Su Jong Yu, Dong Hyun Sinn, Yoon Jun Kim, Joon Hyeok Lee, Jung-Hwan Yoon

O-041 Hepatic Safety and Biomarker Assessments in Sorafenib-Experienced Patients with Advanced Hepatocellular Carcinoma Treated with Nivolumab in the CheckMate-040 Study ············································································································································· 31Thomas Yau, Tim Meyer, Ignacio Melero, Chiun Hsu, Masatoshi Kudo, Su-Pin Choo, Jörg Trojan, Theodore H. Welling, Yoon-Koo Kang, Winnie Yeo, Akhil Chopra, Adyb Baakili, Christine dela Cruz, Huanyu Zhao, Jaclyn Neely, Todd S. Crocenzi, Anthony B. El-Khoueiry, Bruno Sangro

O-042 Development and Validation of Nomograms to Provide Individualized Predictions of Survival Benefits from Surgery in Patients with Intermediate/Advanced Hepatocellular Carcinoma ······························································································································· 32Wen-Tao YAN, Jia-He WANG, Ming-Da WANG, Zheng WANG, Bing QUAN, Ya-Hao ZHOU, Wei-Min GU, Hong WANG, Ting-Hao CHEN, Tian YANG

5. HBV

O-043 Alcohol, Smoking and Overweight as Risk Factors of Hepatocellular Carcinoma in Chronic Hepatitis B Patients on Effective Antiviral Treatment ·························································································································································································· 32Gwang Hyeon Choi, Ju Hyun Shim, Danbi Lee, Kang Mo Kim, Young-Suk Lim, Han Chu Lee, Young-Hwa Chung, Yung Sang Lee

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O-044 Association of Preemptive Anti-HBV Therapy with Improved Long-Term Survival in Patients with Hepatocellular Carcinoma Undergoing Transarterial Therapy ·········································································································································································· 33Jeong Won Jang, Sun Hong Yoo, Seawon Hwang, Pil Soo Sung, Sung Won Lee, Jung Hyun Kwon, Soon Woo Nam, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

O-045 Differential Effect of Hepatitis B Viral Suppression on Hepatocellular Carcinoma Development According to the Phase of Initial Antiviral Treatment: A Multicenter Study ············································································································································· 34Young Chang, Jeong-Hoon Lee, Sung Won Chung, Minseok Albert Kim, Sun Woong Kim, Hyo Young Lee, Junsik Yoon, Yun Bin Lee, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

O-046 Impact of Antiviral Therapy on Risk Prediction Models for Hepatocellular Carcinoma Development in Patients with Chronic Hepatitis B ··· 34Hye Yeon Chon, Tae Seop Lim, Mi Young Jeon, Hye Won Lee, Beom Kyung Kim,Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Seung Up Kim

O-047 Improved Bone and Renal Safety at 1Year after Switching from TDF to TAF: In Chronic HepatitisB(CHB) Patients from East Asia ············· 35Young-Suk Lim, Hyung Joon Kim, Ki Tae Yoon, Won Young Tak, Jae-Seok Hwang, Sang Hoon Ahn, Kwan Soo Byun, Seung Woon Paik, Sook-Hyang Jeong, Yoon Jun Kim, So Young Kwon, John F Flaherty, Vithika Suri Shuyuan Mo, Anuj Gaggar, Ting-Tsung Chang, H. Edward Gane, Henry LY Chan, Wan Long Chuang

O-048 Safety and Efficacy at 1-Year after Switching from TDF to TAF in CHB Patients with Risk Factors for TDF Use ········································· 35Byoung Kuk Jang, Edward Gane, Wai Kay Seto, Harry LA Janssen, Florin A Caruntu, Hyung Joon Kim, Dzhamal Abdurakhmanov, Shuhei Nishiguchi, Andrzej Horban, Ho Bae, John F Flaherty, Anuj Gaggar, Vithika Suri, Shuyuan Mo, G Mani Subramanian, Jia-Horng Kao, Maurizia Brunetto, Maria Buti

O-049 Improvement of Bone Mineral Density and Markers of Proximal Renal Tubular Function in Chronic Hepatitis B Patients Switched from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide ······················································································································ 36Tse-Ling Fong, Brian Lee, Andy Tien, Mimi Chang, Carolina Lim, Ho S. Bae

O-050 Fibrates Significantly Increase the Biochemical Response and Reduce the Risk of Cirrhosis Development in UDCA-Refractory Primary Biliary Cholangitis Patients ······················································································································································· 37Sung Won Chung, Jeong-Hoon Lee, Minseok Albert Kim, Sun Woong Kim, Young Chang, Hyo Young Lee, Joon Sik Yoon, Yun Bin Lee, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

6. Basic

O-051 Immune Tolerant Phase of Perinatal HBV Infection: Are HBV-Specific T Cells Really “Tolerant”?······························································ 38Pil Soo Sung, Dong Joon Park, Ji Won Han, Eun Byul Lee, Jung Hee Kim, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Eui-Cheol Shin, Su-Hyung Park, Seung Kew Yoon

O-052 Higher Asialoglyco Protein Receptor Expression on Placental Cells Is Associated with Hepatitis B Virus Vertical Transmission from Mother to Baby ········································································································································································· 38Ashish Kumar Vyas Sharda Patra, Archana rastogi, Shiv Kumar Sarin, Nirupma Trehanpati

O-053 MicroRNA 17-92 Induces Methylation of Hepatitis B Virus DNA in Human Hepatoma Cells ···································································· 39In Young Moon, Jin-Wook Kim

O-054 Reprogramming of Human Hepatocytes into Bi-Potent Hepatic Progenitor Cells Using Cocktail of Small Molecules and Growth Factor ···· 39Yohan Kim, Kyojin Kang, Sangtae Yoon, Elina Maria Buisson, Chang Hee Lee, Ji-Hye Yim, Jaemin Jeong, Dongho Choi

O-055 The Value of Exosomal microRNA 122 in Liver Disease as Biomarker of Fibrosis: Preliminary Study ·························································· 40Tom Ryu, Jae Young Jang, Se Ri Ryu, Soung Won Jeong, Jeong-Ju Yoo, Sae Hwan Lee, Sang Gyune Kim, Sang-Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, So Young Jin, Boo Sung Kim

O-056 Human Chorionic-Plate-Derived Mesenchymal Stem Cells Restore Hepatic Lipid Metabolism in a Rat Model of Bile Duct Ligation ············ 40Yun Bin Lee, Jong Ho Choi, Eun Nam Kim, Jin Seok, Hyun-Jung Lee, Gi Jin Kim, Jung-Hwan Yoon

O-057 Novel Necroptosis Pathway in Hepatic Fibrosis: MLKL Activated Hepatic Stellate Cell via CXCL1/2 and Adhesion Molecules ····················· 41Dae Won Jun, Waqar K Saeed, Eun Jin Kim, Jae Ha Kim, Jin Hwa Park

O-058 Effects of Probiotics for the Treatment of Non-Alcoholic Fatty Liver Disease in Mice Model ···································································· 41Dae Hee Han, Sang jun Yoon, Haripriya Gupta, Na Young Lee, Ki Tae Suk, Dong joon Kim

7. Surgery-Biliary

O-059 Prognostic Factors for Hilar Cholangiocarcinoma after Surgical Resection: A Retrospective Study of Survival Outcome····························· 41Jeong Woo LEE, Keun Soo AHN, Tae-Seok KIM, Koo Jeong KANG, Yong Hoon KIM

O-060 ERBB Signaling Pathway Targeted Therapy Is Available in Gallbladder Cancer Patients ············································································ 42Xu’an WANG, Maolan LI, Xiangsong WU, Ping DONG, Wei GONG, Yingbin LIU

O-061 Robotic Single-Site Plus One Port Complete Excision of Type I Choledochal Cyst with Hepaticojejunostomy and Extracorporeal Roux-En-Y Bilioenteric Reconstruction in First Experiment ······························································································· 42Jin Ho LEE, Chang Moo KANG, Kook Hwan KWON

O-062 Effect of Sarcopenic Obesity on Postoperative Pancreatic Fistula after Pancreaticoduodenectomy in Patients with Pancreas Head Cancer ····· 43Youngju RYU, In Woong HAN, Dong Wook CHOI, Seong Ho CHOI, Jin Seok HEO, Yung hun YOU, Sunjong HAN, Dae Joon PARK

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O-063 Single Port Laparoscopic Distal Pancreatectomy ··································································································································· 43Hyung Joon Han, Tae-Jin Song, Sae Byeol Choi, Wan-Bae Kim, Young Dong Yu, Dong Sik Kim

O-064 The Single Center Experience of One Thousand Cases of Robotic Pancreatectomy ················································································ 43Rong LIU, Sai CHOU, Zhiming ZHAO, Guodong ZHAO, Yuanxing GAO

O-065 How Aggressive Are Solid Pseudopapillary Tumors of the Pancreas: A Meta-Analysis·············································································44Emmanuel II HAO, Chang Moo KANG

O-066 The Impact of Neoadjuvant Chemotherapy Associated with Intraoperative Radiation Therapy (IORT) in Pancreatic Cancer ······················44Alvaro G. Morales Taboada, Jose Manuel Asencio Pascual, Pablo Lozano Lominchar, Jose Angel Lopez Baena, Enrique Velasco, Luis Rodriguez-Bachiller, Benjamin Diaz Zorita, Arturo Colon, Julio Ferreiroa

8. Liver Transplantation

O-067 Validation of the Alpha-Fetoprotein Model for Hepatocellular Carcinoma Recurrence after Transplantation in an Asian Population ··········44Jinsoo Rhu, Jong Man Kim, Gyu Seong Choi, Choon Hyuck David Kwon, Jae-Won Joh

O-068 The Learning Curve in Pure Laparoscopic Donor Right Hepatectomy: Cumulative Sum Analysis ······························································ 45Suk Kyun Hong, Kyung-Suk Suh, Kyung Chul Yoon, Jeong-Moo Lee, Jae-Hyung Cho, Nam-Joon Yi, Kwang-Woong Lee

O-069 Clinical Features and Surveillance of Very Late Hepatocellular Carcinoma Recurrence after Liver Transplantation ····································· 45Shin Hwang, Su-Min Ha, Chul-Soo Ahn, Ki-Hun Kim, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Gil-Chun Park, Hwi-Dong Cho, Jae-Hyun Kwon, Sang-Hyun Kang, Sung-Gyu Lee

O-070 Renal Safety of Entecavir and Tenofovir with Hepatitis B Immunoglobulin in Liver Transplant Patients ····················································· 46Juhan Lee, Yoon Bin Jung, Deok Gie Kim, Dong Jin Joo, Jun Yong Park, Myoung Soo Kim, Soon Il Kim, Jae Geun Lee

O-071 A New Approach to Overcoming Biliary Complications after Laparoscopic Living Donor Liver Transplantation ········································· 46Ji Soo Lee, Gyu-Seoung Choi, Jong Wook Oh, Young Jae Chung, Jinsoo Rhu, Kyo Won Lee, Jong Man Kim, Jae-Won Joh, Suk-Koo Lee

O-072 A Comparison of Models for Tumor Recurrence After Liver Transplantation for the Patients with Hepatocellular Carcinoma: A Long-Term Multicenter Follow-Up Study ·········································································································································· 46Young Chang, Yuri Cho, Jeong-Hoon Lee, Yun Bin Lee, Eun Ju Cho, Su Jong Yu, Dong Hyun Sinn, Bo Hyun Kim, Seoung Hoon Kim, Nam-Joon Yi, Kwang-Woong Lee, Jong Man Kim, Yoon Jun Kim, Jung-Hwan Yoon, Jae-Won Joe, Kyung-Suk Suh

O-073 Clinical Analysis of Emergency Liver Transplantation in Patients with High MELD Score ·········································································· 47Ho Joong Choi, Dong Goo Kim, Tae Yun Lee, Bong Jun Kwak, Jae Hyun Han, Tae Ho Hong, Young Kyoung You

9. Surgery-Liver

O-074 Comparative Study of Laparosocpic Liver Resection and Open Liver Resection in Patients over 70 Years of Age ······································ 48Hwui-Dong CHO, Ki-Hun KIM, Seok-Hwan KIM, Woo-Hyung KANG, Dong-Hwan JUNG, Gil-Chun PARK, Sung-Gyu LEE

O-075 Novel Classification for Right Posterior Portal Vein (RPPV) Evaluated by SYNAPSE VINCENT ···································································· 48Xu-guang Hu, Ingyu Kim, Sung yeon Hong, Xue-yin Shen,Mina Kim, Bong-Wan Kim, Hee-Jung Wang

O-076 Risk Factors for Surgical Site Infections after Liver Resection (A Multivariate Analysis of 6,132 Patients) ··················································· 48Li-Yang SUN, Jiong-Jie YU, Ju-Dong LI, Xin-Fei XU, Jia-He WANG, Bing QUAN, Wen-Tao YAN, Feng SHEN, Chao LI, Lei LIANG, Tian YANG

O-077 Outcomes after the Liver Resection of Colorectal Cancer Liver Metastases: A Single Center Experience ·················································· 49Jae Ryong SHIM, Sang Jae LEE, Seung Duk LEE, Min Jung KIM, Sung Chan PARK, Seong Hoon KIM, Sung-Sik HAN, Sang Jae PARK, Jae Hwan OH

O-078 Efficacy of Platelet-Rich Fibrin on Bile Duct Anastomosis in a Rat ··········································································································· 49Necdet ÖZÇAY, Ali ÖZANT, Hanife ÖZKAYALAR, Hasan BESIM

O-079 Comprehensive Evaluation of Liver Resection Procedures: Surgical Mind Development through Cognitive Task Analysis ·························· 49Cheng-Maw HO, Go WAKABAYASHI, Chi-Chuan YEH, Rey-Heng HU, Takanori SAKAGUCHI, Takeshi TAKAHARA, Po-Huang LEE

O-080 Laparoscopic Right Hepatectomy without Hanging Maneuver and CUSA ······························································································ 50Jong Man Kim, Sangjin Kim, Jong Wook Oh, Jinsoo Rhu, Young Jae Jeong, Jisoo Lee, Kyung-Sik Kim, Gyu-Seong Choi, Jae-Won Joh

10. Liver Cancer

O-081 Clinical Characteristics of Long Term Survivors Following Sorafenib Treatment for Unresectable Hepatocellular Carcinoma: Korean National Multi-Center Retrospective Cohort Study ···················································································································· 50Young Youn Cho, Su Jong Yu, Hye Won Lee, Do Young Kim, Wonseok Kang, Yong‐Han Paik, Pil Soo Sung, Si Hyun Bae, Su Cheol Park, Young Seok Doh, Kang Mo Kim, Eun Sun Jang, In Hee Kim, Won Kim, Yoon Jun Kim

O-082 New Prediction Model of Convolutional Neural Network for Hepatocellular Carcinoma in Patients of Hepatitis B Virus-Related Cirrhosis on Potent Antiviral Therapy with Comparison of Preexisting Models ······················································································· 51Joon Yeul Nam, Jong Ho Lee, Hee Yoon Jang, Kanghyug Choi, Ingyoon Ha, Eun Sun Jang, Jin-Wook Kim, Sook-Hyang Jeong

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O-083 The Current Surveillance Strategy Does Not Improve the Detection Rate of Small Hepatocellular Carcinoma: A Single-Center Experience in South Korea ·································································································································································· 51Minah Jon, Jae-Jun Shim, Shin Ju Oh, In Zoo Choi, Chi Hyuck Oh, Byung-Ho Kim

O-084 Metformin-Associated Chemopreventive Effects on Recurrence after Hepatic Resection of Hepatocellular Carcinoma: From in vitro to a Clinical Study ·························································································································································· 52Shin Hwang, Woo-Hyoung Kang, Eunyoung Tak, Gi-won Song, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Dong-Hwan Jung, Gil-Chun Park, Sung-Gyu Lee

O-085 A Nationwide Analysis of Conditional Survival Estimates for Korean Patients with Hepatocellular Carcinoma ·········································· 53Jae Seung Lee, Jun Yong Park, In Rae Cho, Hye Won Lee, Mi Young Jeon, Tae Seop Lim, Do Young Kim, Kwang-Hyub Han

O-086 Targeting the Crosstalk between Cytokine-Induced Killer Cells and Myeloid Derived Suppressor Cells in HCC ········································· 53Su Jong Yu, Chi Ma, Bernd Heinrich, Zachary J. Brown, Milan Sandhu, Qianfei Zhang, Qiong Fu, David Agdashian, Firouzeh Korangy, Tim F. Greten

O-087 Sarcopenia Measured by Psoas Muscle Index Is an Independent Factor for Overall Survival in Korean Patients with Hepatocellular Carcinoma ··································································································································································· 54Hee Yoon Jang, Sook-Hyang Jeong, Sung Ho Hwang, Ju Hyun Lee, Joo Yeong Baeg, Joong Mo Ahn, Jung Wha Chung, Jin-Wook Kim, Eun Sun Jang, Youngrok Choi, Jai Young Cho, Ho-Seong Han

O-088 Clinical Impact of CD4+CD25+Foxp3+ Regulatory T Cell in Hepatocellular Carcinoma Patients Undergoing Transarterial Chemoembolization ··········································································································································································· 54Hana Park, Jae Hyung Jung, Min Kyung Jung, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Simon Weonsang Ro, Jeon Han Park, Eui-Cheol Shin, Kwang-Hyub Han

O-089 Caveolin-1 Promotes Hepatocarcinogenesis in Cirrhotic Liver ················································································································ 55Sun Young Yim, Ji-Hyun Shin, Yun Seong Jeong, Sang-Hee Kang, Young Nyun Park, Yeon Seok Seo, Soon Ho Um, Ju-Seog Lee

O-090 Is the Anatomical Resection Necessary for Single Hepatocellular Carcinoma Smaller than 3 cm? ····························································· 55Seong Wook SHIN, Tae-Seok KIM, Jeong Woo LEE, Keun Soo AHN, Yong Hoon KIM, Koo Jeong KANG

11. HCV

O-091 Clinical and Epidemiological Features of Hepatitis C Virus Infection in South Korea from 2007 to 2017: A Prospective, Multicenter Cohort Study ··································································································································································· 56Joon Yeul Nam, Eun Sun Jang, Young Seok Kim, Youn Jae Lee, In Hee Kim, Sung Bum Cho, Han Chu Lee, Si Hyun Bae, Moran Ki, Eun Young Lee, Sook-Hyang Jeong

O-092 A Tool to Measure the Impact of Inaction towards Elimination of Hepatitis C: A Case Study in Korea ····················································· 56Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han

O-093 SVR Rate (12 Weeks and 1 Year) and Improvement of Fibrosis after Daclatasvir/Asunaprevir Treatment in Genotype 1b HCV-Infected Patients ········································································································································································· 57Hannah Ra, Seung Kak Shin, So Jeong Kim, Gyu Cheon Kyung, Youn-i Choi, Oh Sang Kwon, Jong-Beom Shin, Young-Joo Jin, Jin-Woo Lee, Sangheun Lee, Ki Jun Han, Young Nam Kim, Tae Hun Kim, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim

O-094 Ribavirin May Help to Improve Sustained Virological Response of Daclatasvir Plus Asunaprevir for Chronic Hepatitis C 1b Patients ··········· 57Young Kul Jung, Sang Jun Suh, Ji Hoon Kim, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun, Soon Ho Um

O-095 Twelve Weeks of Ledipasvir/Sofosbuvir for Patients with Chronic Hepatitis C Genotype 2 Infection: Integrated Analysis of Three Clinical Studies ·········································································································································································· 57Chung-Feng Huang, Yasuhiro Asahina, Chun-Jen Liu, Edward Gane, Yoshito Itoh, Norifumi Kawada, Yoshiyuki Ueno, Jin Youn, Chen-Yu Wang, Joe Llewellyn, Anu Osinusi, Jenny Svarovskaia, Hongmei Mo, Gerald Crans, Wan-Long Chuang, Pei-Jer Chen, Nobuyuki Enomoto

O-096 Safety and Efficacy of Elbasvir/Grazoprevir in Asian Participants with Hepatitis C Virus Genotypes 1 and 4 Infection ································ 58Wei Lai, Hiromitsu Kumada, Ponni Perumalswami, Tawesak Tanwandee, Wendy Cheng, Jeong Heo, Pin Nan Cheng, Peggy Hwang, Sheng Mei Mu, Xu Min Zhao, Michael Robertson, Barbara Haber, Rohit Talwani, Eungeol Sim

O-097 Efficacy and Safety of Glecaprevir/Pibrentasvir in Renally-Impaired Patients with Chronic HCV Genotype 1-6 Infection ···························· 58Marcello Persico, Robert Flisiak, Manal Abunimeh, Meghan Sise, Jun Yong Park, Marwan Kaskas, Annette Bruchfeld, Marcus-Alexander Wörns, Andrea Aglitti, Zhenyi Xue, Janean Rullman Ariel Porcalla, Eric Cohen, Roger Trinh, Eric Lawitz

12. Liver Cancer

O-098 Transarterial Chemoebolization-Stereotactic Body Radiation Therapy versus Transarterial Chemoebolization for ≤5cm Hepatocellular Carcinoma: Propensity Score Matching ················································································································································ 59Baek Gyu Jun, Sang Gyune Kim, Young Don Kim, Gab Jin Cheon, Koon Hee Han, Jeong-Ju Yoo, Young Seok Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Suyeon Park, Hong Soo Kim

O-099 Risk Assessment and Suitability of Transarterial Chemoembolization in Patients with Unresectable Hepatocellular Carcinoma with or without Impaired Hepatic Function ······················································································································································ 61A Reum Choe, Joon Yeul Nam, Jeong-Hoon Lee, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon, Hyo-Cheol Kim, Jin Wook Chung, Hye Ah Lee, Tae Hun Kim, Kwon Yoo, Hwi Young Kim

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O-100 Surgical Resection versus Radiofrequency Ablation in Single Small Hepatocellular Carcinoma: Data from Korea Central Cancer Registry for Hepatocellular Carcinoma Database ·································································································································· 62Han Ah Lee, Yoo Ra Lee, Tae Hyung Kim, Sun Young Yim,Young-Sun Lee, Sang Jun Suh, Young Kul Jung, Ji Hoon Kim, Yeon Seok Seo, Dong-Sik Kim, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun, Soon Ho Um, The Korean Liver Cancer Association, Ministry of Health and Welfare, Korea Central Cancer Registry

O-101 Down-Regulation of microRNA-100 and Up-Regulation of microRNA-582 Are Associated with Vascular Invasion and Poor Prognosis in Hepatocellular Carcinoma ········································································································································ 62Yongkeun Park

O-102 Risk Factors, Patterns, and Outcomes of Late Recurrence after Liver Resection for Patients with Hepatocellular Carcinoma (Analysis of a Multicenter Cohort over 15 Years) ·································································································································· 63Xin-Fei XU, Jiong-Jie YU, Ju-Dong LI, Hao XING, Jun HAN, Zhen-Li LI, Han WU, Han ZHANG, Jian-Hong ZHONG, Yi-Sheng HUANG, Ya-Hao ZHOU, Ting-Hao CHEN, Hong WANG, Wei-Min GU, Feng SHEN, Tian YANG

O-103 Predicting Hepatocellular Carcinoma Recurrence beyond Milan Criteria after Liver Resection for Solitary Hepatocellular Carcinoma ·········· 63Jong Man Kim, Jae-Won Joh, Nam-Joon Yi, Gyu-Seong Choi, Kyunga Kim, Choon Hyuck David Kwon, Kwang-Woong Lee, Kyung-Suk Suh

O-104 Conventional versus Drug-Eluting Beads Transarterial Chemoembolization for Nodular Hepatocellular Carcinoma in a Superselective Fashion Using Cone-Beam CT: Retrospective Analysis of a Five-Year Outcome ································································ 64In Joon Lee, Jin Wook Chung, Myungsu Lee, Saebeom Hur, Hyo-Cheol Kim

13. Liver Cancer

O-105 Heterogeneous Exhaustion Status of Tumor-Infiltrating CD8 T Cells Determines Distinct Subgroups of Hepatocellular Carcinoma Patients ··· 64Hyung-Don Kim, Gi-Won Song, Seongyeol Park, Min Kyung Jung, Kijong Yi, Min Hwan Kim, Hyo Jeong Kang, Changhoon Yoo, Kyung Hwan Kim, Sukyeong Eo, Deok-Bog Moon, Seung-Mo Hong, Young Seok Ju, Eui-Cheol Shin, Shin Hwang, Su-Hyung Park

O-106 Tumor-Stroma Crosstalk Enhances REG3A Expressions that Drives the Progression of Hepatocellular Carcinoma ···································· 65Yuri Cho, Min ji Park, Koeun Kim, Jung-Hwan Yoon

O-107 A Novel Thermal Accelerant for Augmentation of Microwave Energy during Image-Guided Thermal Ablation of Tumors ······················· 66William PARK, Damian DUPUY

O-108 Protein Disulfide Isomerase Inhibition Synergistically Enhances the Efficacy of Sorafenib for Hepatocellular Carcinoma ····························· 66Jae-Kyung Won, Su Jong Yu, Chae Young Hwang, Sung-Hwan Cho, Sang-Min Park, Kwangsoo Kim, Won-Mook Choi, Hyeki Cho, Eun Ju Cho, Jeong-Hoon Lee, Kyung Bun Lee, Yoon Jun Kim, Kyung-Suk Suh, Ja-June Jang, Chung Yong Kim, Jung-Hwan Yoon, Kwang-Hyun Cho

O-109 Anti-Tumor Effect of Ginsenoside Rh2 and Rg5 in Xenograft Hepatoma Animal Model: Comparison with Sorafenib ······························ 66Han Seul Park, Jae Young Jang, Soung Won Jeong, Jeong-Ju Yoo, Sae Hwan Lee, Sang Gyune Kim, Sang-Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, So Young Jin, Boo Sung Kim

O-110 EpCAM-High Liver Cancer Stem Cells Resist Natural Killer Cell-Mediated Cytotoxicity by Upregulation of Cell Surface CEACAM1 ············ 67Dong Jun Park, Pil Soo Sung, Jung-Hee Kim, Gil Won Lee, Seung Kew Yoon

O-111 Cereblon as a Novel Prognostic Biomarker for Small Hepatocellular Carcinoma ······················································································ 67Shin Hwang, Sung-Hwa Kang, Kyong-Jin Lee, Eunyoung Tak, Young-Joo Lee, Ki-Hun Kim, Chul-Soo Ahn, Deog-Bog Moon, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung

14. Cirrhosis

O-112 Characterization of Cirrhotic Cardiomyopathy Using Cardiac Magnetic Resonance Imaging: A Prospective Study ···································· 68Yun Bin Lee, Hyue Mee Kim, Sung Won Chung, Minseok Albert Kim, Sun Woong Kim, Jun Sik Yoon, Hyo Young Lee, Young Chang, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon, Hyung-Kwan Kim, Jeong-Hoon Lee

O-113 Effects of Branched-Chain Amino Acids (BCAAs) on the Progression of Advanced Liver Disease a Korean Nationwide, Multicenter, Prospective, Observational, Cohort Study ············································································································································ 69Jung Gil Park, Won Young Tak, Soo Young Park, Young Oh Kweon, Se Young Jang, Yu Rim Lee, Si Hyun Bae, Do Young Kim, June Sung Lee, Ki Tae Suk, In Hee Kim, Heon Ju Lee, Woo Jin Chung, Byoung Kuk Jang, Jeong Ill Suh, Jeong Heo, Jae Young Jang, Myung Jin Oh, Won Kee Lee

O-114 Association between Sarcopenia and Minimal Hepatic Encephalopathy and Quality of Life in Patients with Liver Cirrhosis ······················· 69Do Seon Song, Dae Won Jun, Jae Yoon Jeong, Tae Yeob Kim, Sang Bong Ahn, Hee Yeon Kim, Young Kul Jung, Myeong Jun Song, Sung Eun Kim, Hyoung Su Kim, Soung Won Jeong, Sang Gyune Kim, Tae Hee Lee, Yong Kyun Cho, Eileen L. Yoon, Jin Mo Yang

O-115 Presence of Sarcopenia and Its Rate of Change are Independently Associated with Long-Term Mortality in Patients with Liver Cirrhosis··· 70Hyun Joo Choi, Jae Yoon Jeong, Joo Hyun Sohn, Sanghyeok Lim, Jae Gon Lee, Dae Won Jun, Yongsoo Kim

O-116 Efficacy of 4-Weeks Taurine Replacement to Improve Muscle Cramp in Patients with Liver Cirrhosis – A Single Arm, Pilot Study ············· 70Eun Sun Jang, Sung Ho Hwang, Jin-Wook Kim, Sook-Hyang Jeong

O-117 High-Volume Plasma Exchange in Patients with Acute Liver Failure: Initial Experience in Single Liver-Transplantation Center ····················· 71Nam Joong Kim, Sejong Chun, Dong-Hyun Sinn, Semi Kim, Wonseok Kang, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Jong Man Kim, Gyu-Seong Choi, Jae-Won Joh, Duck Cho

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15. HCV

O-118 An Integrated Analysis of the Efficacy of Glecaparevir/Pibrentasvir by Geographical Region ···································································· 71Edward Gane, Kazuaki Chayama, Mudra Kapoor, Stuart K Roberts, Jeong Heo, Jia-Horng Kao, Thomas Berg, Philippe J Zamor, Brian Conway, James Park, Sandra S Lovell, Rakesh Tripathi, Federico J Mensa, Hiromitsu Kumada

O-119 Survival Benefits of Direct-Acting Antiviral Therapy in Patients with Decompensated Hepatitis C Cirrhosis ··············································· 72W. Ray Kim, Anu Osinusi, Ajitha Mannalithara, Bo Hyun Kim, Raul Aguilar Schall, Diana Brainard

O-120 Differential Effect of HCV Eradication and Fibrosis Grade on Hepatocellular Carcinoma and All-Cause Mortality······································ 72Yun Bin Lee, Joon Yeul Nam, Jeong-Hoon Lee, Young Chang, Hyeki Cho, Young Youn Cho, Eun Ju Cho, Su Jong Yu, Hwi Young Kim, Dong Ho Lee, Jeong Min Lee, Seong Gyu Hwang, Yoon Jun Kim, Jung-Hwan Yoon

O-121 Response to DAA in HCV Patients with HCC from East Asia: A REAL-C Study with Propensity Score Matching (PSM) ····························· 73Mindie H. Nguyen, Norihiro Furusyo, Dae Won Jun, Ming-Lung Yu, Masaru Enomoto, Jia-Horng Kao, Eiichi Ogawa, Etsuko Ilio, Chen-Hua Liu, Hwai-I Yang, Akihiro Tamori, Chia-Yen Dai, Jee-Fu Huang, Yoshiyuki Ueno, Dong Hyun Lee, Grace Wong, Jun Hayashi, Hideyuki Nomura, Makoto Nakamuta, Hiroaki Haga, Mi Jung Jun, Mei-Hsuan Lee, Yuichiro Eguchi, Hirokazu Takahashi, Shinji Iwane, Sally Tran, Linda Henry, Yasuhito Tanaka for the REAL-C Investigators: Sang Bong Ahn, Koichi Azuma, Wan-Long Chuang, Kazufumi Dohmen, Nobuhiko Higashi, Chung-Feng Huang, Jae Yoon Jeong, Jang Han Jung, Eiji Kajiwara, Masaki Kato, Akira Kawano, Toshimasa Koyanagi, Seung Ha Park, Takeaki Satoh, Shinji Shimoda, Do Seon Song, Kazuhiro Takahashi, Ming-Lun Yeh, Eileen L. Yoon

O-122 Hepatocellular Carcinoma Recurrence after Direct-Acting Antiviral Therapy in Patients with Chronic Hepatitis C: A Korean Multi-Center Retrospective Study ········································································································································· 74Soon Sun Kim, Sun Hyuk Hwang, Hyo Jung Cho, Do Young Kim, Hye Won Lee, Su Jong Yu, Young Youn Cho, Jeong Won Jang, Byoung Kuk Jang, Chang Wook Kim, Hee Yeon Kim, Hana Park, So Young Yoon, Gil Ho Lee, Sung Won Cho, Jae Youn Cheong

O-123 Pretreatment NAFLD Activity Score Significantly Predicts Fibrosis Regression in Hepatitis C Patients Receiving Antiviral Therapy ················ 75Dong Hyeon Lee, Won Kim, Sae Kyung Joo, Yong Jin Jung, Byeong Gwan Kim, Kook Lae Lee

Poster Oral Presentation

Nonalcoholic Fatty Liver Disease / Alcoholic Liver Disease / Toxic Injury

PO-001 NAFLD Is Associated with High Prevalence and High Recurrence Rate in Patients with Breast Cancer ······················································ 78Young-Sun Lee, Sung Won Chang, Ha Seok Lee, Haein Bak, Sehwa Kim, Min-jin Lee, Chan Uk Lee, Young Kul Jung, Ji Hoon Kim, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun

PO-002 Azathioprine Induce Hyperbilirubinemia in Inflammatory Bowel Disease: A Hospital Based Cohort Study················································· 78Kwang Il Seo, Won Moon, Seun Ja Park, Moon In Park, Sang Uk Lee, Byung Chul Yun, Byung Hoon Han, Eun Taek Park

PO-003 The Effects of Non-Pharmacological Interventions for Patients with Non-Alcoholic Fatty Liver Disease: A Systematic Review ···················· 79Jeong Hyun Kim, Ji Yeon Lee, Yeonsoo Jang

PO-004 The Prognostic Stratification Using Acute-On-Chronic Liver Failure Scoring System for Predicting Short-Term Mortality in Patients with Alcoholic Hepatitis ·············································································································································································· 79Do Seon Song, Dong Joon Kim, Korean Acute on Chronic liver failure(KACLiF), Ji Dong Jia, Ashok Kumar Choudhury, Mamun Al Mahtab, Harshad Devarbhavi, Z Duan, Chen Yu, C E Eapen, Ashish Goel, Q Ning, Ke Ma, Y K Chawla, R K Dhiman, Ajay Duseja, Sunil Taneja, S S Hamid, Amna S Butt, Wasim Jafri, S S Tan, Hasmik Ghazinian, Deepak n Amarapurkar, Sombat Treeprasertsuk, G H Lee, S G Lim, Jinhua Hu, L A Lesmana, Cosmas Rinaldi Lesmana, Akash Shukla, Samir Shah, Chetan Kalal, Manoj Sahu, Z Abbas, J D Sollano, Gian Carpio, Fazal Karim, G K Lau, P N Rao, Diana A Payawal, A Kadir, M F Yuen, V G Mohan Prasad, Osamu Yokosuka, Ananta Prasad, Priyanka Jain, Irene Paulson, Shiv K Sarin, AARC working Party

PO-005 Comparative Study on the Ameliorating Effects of Pyrroloquinoline Quinone, S. Cumini and Vitamin C in Liver of STZ-Induced Diabetic Mice: Biochemical and Histopathological Study ···································································································································· 80Narendra Kumar, Anand Kar

PO-006 Handgrip Strength among Korean Adolescents with Elevated Alanine Aminotransferase and Obesity in 2014-2015 ······························· 81Yunkoo Kang, Sowon Park, Seung Kim, Hong Koh

Basic

PO-007 Chemical Derived Patient-Specific Hepatic Stem Cells from Various Patients ·························································································· 81Kyojin Kang, Yohan Kim, Sangtae Yoon, Elina Maria Buisson, Changhee Lee, Ji-Hye Yim, Jaemin Jeong, Dongho Choi

PO-008 Impact of Probiotics in NAFLD in Mice with Western Diet ····················································································································· 82Sang jun Yoon, Dae Hee Han, Haripriya Gupta, Na Young Lee, Ki Tae Suk, Dong joon Kim

PO-009 Formation of Functional Hepatocyte-Like Cells through Direct Conversion and Transplantation into Various Mice Models ······················· 82Sangtae Yoon, Kyojin Kang, Yohan Kim, Elina Maria Buisson, Chang Hee Lee, Ji-Hye Yim, Jaemin Jeong, Dongho Choi

PO-010 Characteristics of Bone Marrow Derived Mesenchymal Stem Cells in Patients with Liver Cirrhosis ··························································· 83Haripriya Gupta, Sang Jun Yoon, Dae Hee Han, Na Young Lee, Ki Tae Suk, Dong Joon Kim

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HBV

PO-011 Two-Center, 24-Months Result of Switching to Tenofovir-Monotherapy in Multi-Drug Experienced Chb Patients ··································· 83Eileen L. Yoon, Jeong Han Kim, Won Hyeok Choe, So Young Kwon, Won-Choong Choi, Byung-chul Yoo

PO-012 Medication Nonadherence Increases Hepatocellular Carcinoma, Cirrhotic Complications and Mortality in Chronic Hepatitis B Patients Treated with Entecavir ········································································································································································ 84Hee Jung Jun, Jung Woo Shin, Seok Won Jung, Seung Bum Lee, Bo Ryung Park, Jae Ho Park, Byung Gyu Kim, In Du Jeong, Sung-Jo Bang, Neung Hwa Park

PO-013 Efficacy and Safety of Tenofovir with and without Ursodeoxycholic Acid in Chronic Hepatitis B Patients with Elevated ALT: Interim Analysis of Phase 2 Randomized, Double-Blinded, Placebo-Controlled Study ·············································································· 84Hee Yeon Kim, Chang Wook Kim, Ji Young Kim, Seung Up Kim, Beom Kyung Kim, Jung Hyun Kwon, Soon Woo Nam, Joo Ho Lee, Seong Gyu Hwang, Hana Park, Hyung Jum Yim, Young Kul Jung, Jae Youn Cheong, Soon Sun Kim

PO-014 Mortality, Liver Transplantation and Hepatic Complications among Patients with Treatment-Naïve Chronic Hepatitis B with Entecavir vs. Tenofovir ········································································································································································ 85Hee Jung Jun, Seung Bum Lee, Neung Hwa Park, Bo Ryung Park, Seok Won Jung, Jae Ho Park, Byung Gyu Kim, In Du Jeong, Sung-Jo Bang, Jung Woo Shin

PO-015 Clinical Characteristics and Prevelance of Hepatitis Delta Virus Infection in Patients with Chronic Hepatitis B in Korea ······························ 85Young Kul Jung, Dong-won Lee, Ja Seol Koo, Jung Wan Choe, Sang Jun Suh, Seung Young Kim, Jong Jin Hyun, Sung Woo Jung, Hyung Joon Yim, Sang Woo Lee

PO-016 The Risk of Hepatocellular Carcinoma within and after the First 5 Years of Entecavir in Patients with Chronic Hepatitis B ························ 85Seung Bum Lee, Soyoung Jeon, Jae Ho Park, Byung Gyu Kim, Seok Won Jung, In Du Jeong, Sung-Jo Bang, Jung Woo Shin, Neung Hwa Park, Hee Jung Jun

HBV

PO-017 A Long Term Clinical Outcomes of Pegylated Interferon Treatment in Patients with Chronic Hepatitis B: Up to 10 Years Follow-Up ········· 86Kyoung Won Baik, Jung Hyun Kwon, Sun Hong Yoo, Soon Woo Nam, Jeong Won Jang

PO-018 Efficacy and Safety of Entecavir and Tenofovir in Chronic Hepatitis B Patients with Chronic Kidney Disease: Multicenter, Retrospective Cohort Study ································································································································································ 86Sung Eun Kim, Jae Yoon Jeong, Dae Won Jun, Eileen L. Yoon, Jae-Jun Shim, Sang Bong Ahn, Yong Kyun Cho, Soung Won Jeong, Hyoung Su Kim

PO-019 Association between Hepatic Steatosis and the Development of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B ·············· 87Yun Bin Lee, Yeonjung Ha, Young Eun Chon, Mi Na Kim, Joo Ho Lee, Hana Park, Kyu Sung Rim, Seong Gyu Hwang

PO-020 Increasing Age and Comorbidities in Adult Patients with Chronic Hepatitis B (CHB) from 2007 to 2016 in Korea ···································· 88Dae Won Jun, Hyunwoo Oh, Hyun Jung Ahn, Bo Ok Kim, Mindie H. Nguyen

PO-021 No Resistance to Tenofovir Alafenamide Detected through 96 Weeks of Treatment in Patients with Chronic Hepatitis B ························ 88Won Young Tak, Henry Lik-Yuen Chan, Patrick Marcellin, Calvin Q. Pan, Andrea L Cathcart, Neeru Bhardwaj, Yang Liu, Stephanie Cox, Bandita Parhy, Eric Zhou, John F Flaherty, Michael D Miller, Anuj Gaggar, Shalimar, Namiki Izumi, Young-Suk Lim

PO-022 Predictors of HBeAg Loss and Seroconversion by Clinical Features and Viral Sequencing after 144 Weeks of Treatment with Tenofovir Alafenamide or Tenofovir Disoproxil Fumarate ····································································································································· 89Yoon Jun Kim, Young-Suk Lim, Shalimar, Xiaoli Ma, Akash Shukla, Huy N. Trinh, Pietro Andreone, Jae-Seok Hwang, Vithika Suri, George Wu, Ondrej Podlaha, Anuj Gaggar, John F. Flaherty, Wan-Cheng Chow, Patrick Marcellin, Namiki Izumi

HBV

PO-023 Clinical Impact and Durabilty of Hepatitis B Surface Antigen Seroclearance in Untreated and Nucleos(t)ide Analogue Treated Patients ····· 89Yonsoo Kim, Hyun Woong Lee, Jung Il Lee, Kwan Sik Lee

PO-024 Comparison of Risk for Hepatocellular Carcinoma in Chronic Hepatitis B Patients Treated with Entecavir and Tenofovir ·························· 90Ingyoon Ha,, Eun Sun Jang, Sook-Hyang Jeong, Jin-Wook Kim

PO-025 Baseline Factors Associated with Compensation in Patients with Hepatitis B Virus-Related Decompensated Cirrhosis Commencing Antiviral Therapy ··························································································································································· 90Tae Hyung Kim, Soon Ho Um, Yoo Ra Lee, Han Ah Lee, Sun Young Yim, Young Sun Lee, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Ji Hoon Kim, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun

PO-026 Long-Term Clinical Outcomes of Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir: A Multi-Institutional, Retrospective, Observational and Comparative Study ················································································································································· 91Byeong Wook Cho, Ji Woong Jang, Hee bok Chae, Suk Bae Kim, Il Han Song

PO-027 Impact of HBeAg Seroclearance on the Risk of HCC Development in HBeAg-Positive Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir ········································································································································································· 91Jonggi Choi, Seungbong Han, Gi-Ae Kim, Young-Suk Lim

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PO-028 Incidence and Risk Factors of Hepatitis B Virus Reactivation in HBsAg-Negative, Anti-HBc-Positive Kidney Transplant Recipients ··············· 91Hyo Young Lee, Eun Ju Cho, Sungwon Chung, MinSeok Albert Kim, Sun Woong Kim, Jun Sik Yoon, Young Chang, Yun Bin Lee, Jeong-Hoon Lee, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

Cirrhosis

PO-029 Four Steps for the Surgical Treatment of Hepatic Hydrothorax ·············································································································· 92Yochun Jung, Sang Yun Song, Kook Joo Na, In Seok Jeong, Soon-Ho Chon, Chung Hwan Jun, Sung Kyu Choi

PO-030 Phase 1/2a Trial of a Bioartificial Liver Support System (LifeLiver) for Acute Liver Failure Patients ····························································· 93Sanghoon Lee, Ji-Hyun Lee, Doo-Hoon Lee, Dong Hyun Sinn, Choon Hyuck David Kwon Jeong-Kwon Noh, In Keun Jang, Hey-Jung Park, Hee-Hoon Yoon, Suk-Koo Lee

PO-031 Management of Hydrothorax in Cirrhotic Patients: Is Surgical Management Safe and Efficient? ······························································ 93Jae Hyun Yoon, Dong Hyun Kim, Jiyun Hong, Chung Hwan Jun, Sung Bum Cho, Yo Chun Jung, Sung Kyu Choi

PO-032 Impact of Liver Fibrosis on Long-Term Outcome in Ischemic Stroke Patients ·························································································· 94Seung Up Kim, Minyoul Baik, Sungwoo Kang, Hyung Jong Park, Hyo Suk Nam, Ji Hoe Heo, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Young Dae Kim

PO-033 Efficacy and Tolerance of Maximally Tolerable Dose of Propranolol in the Prevention of Esophageal Variceal Rebleeding ························· 94Jeong Eun Song, Byung Seok Kim, Chang Hyeong Lee

PO-034 Usefulness of Linear Type Wireless Hand-Held Ultrasound for the Evaluation of Liver Surface Nodularity in Patents with Liver Cirrhosis ···· 94Seung Kak Shin, Yun Soo Kim, Hannah Ra, Sangho Jeong, Hyung Nam Kim, Oh Sang Kwon, Duck Joo Choi, Ju Hyun Kim

Cirrhosis

PO-035 Optimal Selection of Sedative Drug during Gastroduodenoscopy in Cirrhotic Patients to Avoid Minimal Encephalopathy: Interim-Analysis of Randomized Controlled Trial ··································································································································· 95Jeong-Ju Yoo, Hyeon Jeong Goong, Sang Gyune Kim, Young Seok Kim , Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Baek Gyu Jun, Young Don Kim, Gab Jin Cheon, Min Sung Kim

PO-036 Sarcopenia Is Independently Associated with Significant Fibrosis Assessed Using Transient Elastography in Patients with Chronic Liver Disease ·········································································································································································· 95Kyung Hyun Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Seung Up Kim

PO-037 The Usefulness of Child-Turcotte-Pugh Class plus Hepatic Venous Pressure Gradient Model in Low and Intermediate MELD Era ·············· 96Tom Ryu, Jae Young Jang, Tae Yeob Kim, Ki Tae Suk, Moon Young Kim, Soung Won Jeong, Dong Joon Kim, Soon Koo Baik, Joo Hyun Sohn, Woo Kyoung Jeong, Eun Hee Choi

PO-038 Role of Plasma Cystatin C and Urine NGAL in Prediction of Acute Kidney Injury and Mortality in Patients with Acutely Decompensated Cirrhosis: A Prospective Cohort Study ························································································································ 96Sang Muk Hwang, Ji Hyun Yang, Sang Kyung Jo, Myung Seok Lee, Sang Hoon Park

PO-039 Relationship between Timing of Endoscopy and Mortality in Cirrhotic Patient with Variceal Bleeding ······················································ 97Jeong-Ju Yoo, Young Chang, Eun Ju Cho, Sang Gyune Kim, Young Seok Kim, Yun Bin Lee, Jeong-Hoon Lee, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

PO-040 Comparison of Liver Volume of Chronic Liver Disease between Viral and Non-Viral Etiology by Using Computed Tomography Volumetry ···· 97Ingyoon Ha, Jin-Wook Kim, Eun Sun Jang, Sook-Hyang Jeong

Liver Transplantation

PO-041 Clinical Outcomes of Patients with Injuries of Adjacent Organs by Expanded Polytetrafluoroethylene Grafts Used for Middle Hepatic Vein Reconstruction in Right Lobe Living Donor Liver Transplantation: A Single-Center Real-World Experience ···························· 98Hye Young WOO, Suk Kyun HONG, Kyung-Suk SUH, Min Seob KIM, Kyung Chul YOON, Jeong-Moo LEE, Jae-Hyung CHO, Nam-Joon YI, Kwang-Woong LEE

PO-042 Totally Laparoscopic Living Donor Right Hepatectomy in Bile Duct Anomalies ························································································ 98Ja Ryung HAN, Heon Tak HA, Hyung Jun KWON, Jae Min CHUN, Sang-Geol KIM, Yoon Jin HWANG, Young Seok HAN

PO-043 The Effect of Tacrolimus Intrapatient Variability on the Transplant Outcomes in Liver Transplantation ····················································· 99Juhan Lee, Yoon Bin Jung, Deok Gie Kim, Dong Jin Joo, Myoung Soo Kim, Soon Il Kim, Jae Geun Lee

PO-044 Changes of Standardized Uptake Value in 18F-FDG Positron Emission Tomography after Recurrence of Hepatocellular Carcinoma in Patients with Sirolimus in Living Donor Liver Transplantation ················································································································· 99Kyung Chul YOON, Kwang-Woong LEE, Suk Kyun HONG, Jeong-Moo LEE, Jae-Hyung CHO, Nam-Joon YI, Kyung-Suk SUH

PO-045 Risk Factors for Renal Impairment at One-Year after Liver Transplantation ····························································································· 99Hae Lim Lee, Jung Hyun Kwon, Sun Hong Yoo, Sung Won Lee, Soon Woo Nam, Jong Youl Lee, Young Chul Yoon, Jun Suh Lee, Gun Hyung Na, Il Young Park, Jeong Won Jang, Jong Young Choi

PO-046 Laparoscopy of Hepatocellular Carcinoma Is Helpful in Minimizing Intra-Abdominal Adhesion during Salvage Transplantation ··············· 100Jinsoo RHU, Jong Man KIM, Gyu Seong CHOI, Choon Hyuck KWON, Jae-Won JOH, Olivier SOUBRANE, Kyo Won LEE

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Biliary and Pancreatic Disease

PO-047 Dual-Incision Laparoscopic Spleen-Preserving Distal Pancreatectomy ; Merits in the Surgical Aspect Compared with Conventional Method······································································································································································· 100Eun Young KIM, Young Kyoung YOU, Dong Goo KIM, Tae Ho HONG

PO-048 Totally Laparoscopic Pancreaticoduodenectomy Using 3D Flexible Laparoscopic System ········································································101Heon Tak HA, Ja Ryung HAN, Hyung Jun KWON, Jae Min CHUN, Sang-Geol KIM, Yoon Jin HWANG, Young Seok HAN

PO-049 The Value of Infectious Biomarkers for Prediction of Complication after Pancreatic Surgery···································································101Yuan FANG, Gang JIN, Xubao LIU, Yajin CHEN, Bei SUN, Zhongtao ZHANG, Wenchuan WU, Wenhui LOU

PO-050 Portal Vein Stenting for Symptomatic Portal Vein Occlusion after Pancreaticoduodenectomy ································································101Young Ju RYU, Dae Joon PARK, Jin seok HEO, In Woong HAN, Seong Ho CHOI, Dong Wook CHOI

PO-051 A Prospective, Pilot Study to Evaluate the Safety and Efficacy of the Unity Balloon-Expandable Bioresorbable Biliary Stent System in Subjects with Benign Biliary Strictures ························································································································ 102Hairol Othman, Zamri Zuhdi, Azlanudin Azman, Chik Ian, Razman Jarmin

PO-052 The Content of Cytokines in Ductal Bile and Serum with Obstructive Jaundice of Non-Tumor Origin ···················································· 102Toshnazarov J.F., Sagatova D.Sh., Lukmonov S.N., Madatov K.A., Toshtemirov S.G.

HCV

PO-053 Long-Term Follow-Up of Patients with Chronic HCV Infection and Compensated or Decompensated Cirrhosis Following Treatment with Sofosbuvir-Based Regimens ······································································································································ 103Alessio Aghemo, Alessandra Mangia, Eric Lawitz, Ed Gane, Brian Conway, Peter J. Ruane, Armando Abergel, Sooji Lee, Brian McNabb, Anu Osinusi, Frances Chen, Hadas Dvory-Sobol, Diana M. Brainard, G. Mani Subramanian, Barbara Leggett, Jose Luis Calleja, Tobias Goeser, Kosh Agarwal, Ziad Younes, Andrew Muir

PO-054 Integrated Analysis of Elbasvir/Grazoprevir Clinical Trials in Korean Participants with Hepatitis C Virus Genotype 1b Infection················· 104Do Young Kim, Youn Jae Lee, Jeong Heo, Woo Jin Chung, Won Young Tak, Yoon Jun Kim, Seung Woon Paik, Eungeol Sim, Susila Kulasingam, Rohit Talwani, Barbara Haber, Peggy Hwang

PO-055 Rapid Virological Response, as a Predictor of Sustained Virologic Response of Sofosbuvir and Ribavirin in Korean Patients with Genotype 2 Chronic Hepatitis C Virus Infection ············································································································· 104Hyun Young Woo, Sung Yong Han, Jeong Heo, Young Joo Park, Sang Gyu Park, Young Mi Hong, Ki Tae Yoon, Mong Cho

PO-056 The Risk of HBV Reactivation among HBV/HCV Co-Infected Patients Treated with Direct-Acting Antiviral Agents: A Single Center Experience ······················································································································································································· 105Young Joo Park, Hyun Young Woo, Jeong Heo, Young Mi Hong, Ki Tae Yoon, Mong Cho

PO-057 Predictors of Major Clinical Adverse Events in Genotype 1 Hepatitis C Patients Receiving Direct-Acting Antiviral Therapy: A Multicenter Cohort Study ······························································································································································ 105Sung Won Lee, Hae Lim Lee, Nam Ik Han, Hee Yeon Kim, Chang Wook Kim, Chan Ran You, Sang Wook Choi, Se Hyun Cho, Joon-Yeol Han, Do Seon Song, U Im Chang, Jin Mo Yang, Sun Hong Yoo, Jung Hyun Kwon, Soon Woo Nam, Seok-Hwan Kim, Myeong Jun Song, Seawon Hwang, Pil Soo Sung, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

PO-058 FIB-4 at Sustained Virological Response Independently Predicts Hepatocellular Carcinoma Development among Chronic Hepatitis C Patients Treated with Interferon-Based Regimen ··············································································································· 105Hosoo Chun, Beom Kyung Kim, Jun Yong Park, Do Young Kim,Sang Hoon Ahn, Kwang-Hyub Han, Seung Up Kim

HCV & Infectious disease

PO-059 Efficacy and Tolerability of Elbasvir/Grazoprevir and Ombitasvir/Paritaprevir/Ritonavir with Dasabuvir in HCV Genotype I-Infected Korean Patients : Analyses in Real-Life Settings ·································································································································· 106Seawon Hwang, Sung Won Lee, Pil Soo Sung, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jung Hyun Kwon, Sun Hong Yoo, Soon Woo Nam, Hae Lim Lee, Nam Ik Han, Hee Yeon Kim, Chang Wook Kim, Do Seon Song, U Im Chang, Jin Mo Yang, Seok-Hwan Kim, Myeong Jun Song, Chan Ran You, Sang Wook Choi, Se Hyun Cho, Joon-Yeol Han, Jeong Won Jang

PO-060 Changes in Lipid Profiles of Patients with Chronic Hepatitis C after Therapy with Direct Acting Antiviral (DAA) ····································· 106Yong Seok Lim, Jeong-Ju Yoo, Sang Gyune Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Boo Sung Kim, Young Don Kim, Gab Jin Cheon, Baek Gyu Jun, Young Seok Kim

PO-061 Efficacy and Safety of Direct-Acting Antivirals for Treatment of Chronic Hepatitis C Patients ································································ 107Seong Jun Park, Won Hyeok Choe, Jeong Han Kim, Byung Chul Yoo, Ah Ran Kim, So Young Kwon

PO-062 The Optimal Management of Pleural Effusion in Liver Abscess? ·········································································································· 107Se Ri Ryu, Jae Young Jang, Tom Ryu, Soung Won Jeong, Youngyun Cho, Jeeyeon Kim, Jeong-Ju Yoo, Sae Hwan Lee, Sang Gyune Kim, Sang-Woo Cha,Young Seok Kim, Young Deok Cho, Hong Soo Kim, Boo Sung Kim

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PO-063 The Clinical Features of Multidrug-Resistant Bacteria Induced Pyogenic Liver Abscess ··········································································· 108Ji Won Park, Jung Hee Kim, Jang Han Jung, Sung Eun Kim, Hyoung Su Kim, Haemin Jeong, Ki Tae Suk, Myoung Kuk Jang, Sang Hoon Park, Myung Seok Lee, Dong Joon Kim, Choong Kee Park

PO-064 Colorectal Neoplasm in Patients with Pyogenic Liver Abscess: Prevalence, Etiology and Associate Factor ··············································· 108Chan Uk Lee, Ji Hoon Kim, Young-Sun Lee, Jong Eun Yeon, Kwan Soo Byun

Cirrhosis

PO-065 Epidemiological Shift of Hepatitis A Infection: A Single Tertiary Center Experience ··············································································· 109Hwan Hee Park, Ju Ho Lee, Hee Sung Lee, Woo Sun Rou, Hyuk Soo Eun, Jong Seok Joo, Eaum Seok Lee, Byung Seok Lee, Seok Hyun Kim

PO-066 The Survival of Patients with HVPG >12mmHg in Real Clinical Practice-Focusing on “with or without Gastroesophageal Varices” ··········110Se Ri Ryu, Soung Won Jeong, Jae Young Jang, Tae Yeob Kim, Ki Tae Suk, Moon Young Kim, Dong Joon Kim, Soon Koo Baik, Joo Hyun Sohn, Woo Kyoung Jeong, Eun Hee Choi, Su Yeon Park

PO-067 Splenoadrenal Shunt for Noncirrhotic Portal Hypertension ···········