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7th Annual Beirut Breast Cancer Conference

BBCC-7

Organized by:

Naef K. Basile Cancer Institute Breast Center of Excellence,

The Clinical and Professional Development Center and

the Continuing Medical Education Office at the American University of

Beirut Medical Center (AUBMC)

In collaboration with:

Lebanese Order of Physicians LOP

Lebanese Society of Medical Oncology LSMO

Lebanese Society of General Surgery SLCG

Order of Pharmacists in Lebanon OPL

Order of Nurses in Lebanon ONL

Arab Medical Association Against Cancer AMAAC

February 7- 9, 2019,

Gefinor Rotana Hotel, Beirut, Lebanon

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Message from the Activity Director

It is my great pleasure to welcome you again to the

Annual Beirut Breast Cancer Conference, now in its

7th Edition BBCC7 that has an up-to-date

multidisciplinary program for the management of

patients with breast cancer. BBCC-7, also includes

oncology pharmacy, nursing and NGO and advocacy

workshops. We also have special poster and oral

presentations with awards for Junior Researchers for

Best Abstracts and Best Posters.

We have a superb panel of speakers and experts to present CME didactic

lectures, tumor boards and round table discussions presenting updates from

major oncology meetings, including San Antonio, ESMO, ASCO, St.

Gallen, ABC and published literature. Non-CME satellite symposia are

also featured.

We are proud that BBCC has become an annual specialty tradition in

Lebanon and the region and attracts an increasing number of participants,

senior and junior physicians interested in the care of patients with breast

cancer. Beirut Breast Cancer Conference in featured on ASCO Connection

and (https://www.asco.org), AUBMC website (http://www.aubmc.org.lb)

and newspapers and magazines.

On behalf of BBCC-7 Scientific Committee, Breast Center of Excellence

at the Naef K. Basile Cancer Institute, and the CME Office at American

University of Beirut Medical Center, I hope you have a great meeting and

for our guests also an enjoyable stay in Beirut and Lebanon.

Nagi S. El Saghir, MD, FACP, FASCO

Chairperson, BBCC-7

February 2019

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General Information

Program Overview The Breast Center of Excellence of the Naef K. Basile Cancer Institute at

the American University of Beirut Medical Center (AUBMC) organizes its

7th Annual Breast Cancer Conference, Beirut BBCC7, bringing together

the Lebanese Order of Physicians, Lebanese Order of Nurses, Lebanese

Order of Pharmacists, various Lebanese and Arab medical associations and

non-governmental organizations, and Lebanese and International experts

collaborating together in the fight against breast cancer. The program

includes updates on breast cancer patient assessment and treatment

planning, management of chemotherapy side effects, breast conservative

surgery, breast reconstruction, new advances in chemotherapy, anti-HER2

targeted therapy and hormonal therapy and ovarian function suppression,

CDK4/6 inhibitors, Checkpoint Inhibitors Immunotherapy, PARPi, as well

as new research abstracts, as well as two pharmacy and NGO workshops.

Objectives Lebanese and International experts will share new knowledge, discuss

novel advances in screening, loco-regional and systemic assessment,

diagnosis, neoadjuvant therapy, surgery of the breast and axilla, radiation

therapy, chemotherapy, targeted therapy, hormonal therapy, patient

advocacy and support groups, as well as pharmacological and nursing

aspects of care of patients with breast cancer.

Target Audience This annual scientific meeting has been designed for physicians,

researchers, scientists, physicians-in-training and medical students, as well

as pharmacists, nurses, patient advocates. Breast cancer basic and clinical

researchers, policymakers, and research promoters/funders are also

encouraged to attend.

Venue

This conference is held at the Gefinor Rotana Hotel, Beirut, Lebanon.

Accreditation This symposium complies with the Lebanese Order of Physicians

Continuing Medical Education, the Lebanese Order of Pharmacists, the

Order of Nurses in Lebanon and the ANCC guidelines.

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American University of Beirut Medical Center is accredited as a provider

of continuing nursing education by the American Nurses Credentialing

Center’s Commission on Accreditation.

The planning committee and presenters declare no conflict of interest,

including financial interest in product or company presented, direct

research support, or other form of potential bias.

Activity Director

Nagi S. El Saghir, MD, FACP, FASCO

Professor and Head, Division of Hematology Oncology

Department of Internal Medicine

Director of Breast Center of Excellence, NK Basile Cancer Institute

American University of Beirut Medical Center

Beirut, Lebanon.

Scientific Committee

Hazem Assi, MD, Fouad Boulos, Rebecca El Asmar, RN, MSN,

Ghina El-Khatib, RN, Nagi S. El Saghir, MD (Chair),

Lara Nassar, MD, Eman Sbaity, MD, Arafat Tfayli, MD

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Thursday, February 7, 2019

12:00 pm: BBCC-7 Registration Open

14:00pm: Opening Welcome

Dr. Nagi El Saghir

Conference Room: Rotana B

14:00-15:20 Advances in Primary Breast Cancer I Chairs: Drs. Sami Khatib, Selim Nasser, Maher Saifo & Christine Salem

14:00-14:20 Microcalcifications: What do we know and what to do

about them?

Dr. Lara Nassar

14:20-14:40 Breast Cancers with Favorable Histology

Dr. Fouad Boulos

14:40-15:00 Genomic Profiling and adjuvant systemic therapy in

Early Breast Cancer

Dr. Julie Gralow

15:00-15:20 MRI in young women with breast cancer: Yes or No

Dr. Ghina Berjawi

15:20-16:00 Advances in Primary Breast Cancer II Chairs: Drs. Georges Chahine, Hassan Ghazal & Maha Manachi

15:20-15:40 Dual Anti-HER2 Neoadjuvant Therapy

Dr. Sana Al-Sukhun

15:40-16:00 De-escalation of anti-HER2 Therapy

Dr. Hamdy Abdel Azim

16:00-16:20 Coffee Break

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16:20 -17:00: Tumor Boards Round Table Case Discussions I Case Presentations: Drs. George Aftimos, Ghina Berjawi, Nizar Bitar,

Fouad Boulos, Sami Faddoul, Zahera Fahed, Julie Gralow, Sami Khatib,

Tatiana Khoury, Fady Nasr, Arafat Tfayli, Antoine Wadih & Youssef

Zeidan

17:00-18:00: Beirut Breast Cancer Conference BBCC-7: Gefinor

Rotana

Opening Ceremony & Debate:

Breast Cancer in Young Women: Advancing Research and Treatment in

Lebanon

Moderator: Ms. Samar Abou Khalil, Senior TV Anchor

Panel & Guests:

Dr. Nagi El Saghir, Head, Division, Hemato/Oncology, AUBMC

Dr. Hikmat AbdelRazek, Chief Medical Officer, KHCC

Dr. Joseph Maroun, President, Lebanese Society of General Surgery

Dr. Nizar Bitar, President, Lebanese Society of Medical Oncology

Dr. Sami Khatib, President, Arab Medical Association Against Cancer

Dr. Ali Taher, Director, NKBCI Adult Cancer Center, AUBMC

Dr. Mohamad Sayegh EVP/Dean, Faculty of Medicine, AUB

Dr. Myrna Doumit, President, Order of Lebanese Nurses

Dr. Ghassan El-Amine, President, Lebanese Order of Pharmacists

Dr. Omar Ayash, President, Lebanese Order of Physicians in Tripoli

Dr. Raymond Sayegh, President, Lebanese Order of Physicians in Beirut

HE Deputy Prime Minister & Minister of Health Mr. Ghassan Hasbani

18:00-18:45 Non-CME Lecture: Sponsored by an Unrestricted

Educational Grant from Roche

Updates of the Management of HER2 positive eBC

Dr. Marwan Ghosn

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Friday February 8, 2019

08:00 - 12:30 7th Oncology Nursing Symposium Chairs: Dr. Myrna Doumit, Ms. Iman Kouatly & Ms. Zeina Koussa

08:00 – 08:10 Welcome and Introduction

08:10 – 08:30 Inpatients Receiving Chemotherapy: What Should

We Monitor?

Ms. Kristel Dagher

08:30 – 08:50 It’s an Emergency! Or Is It? Identifying the Common

Oncologic Emergencies During Breast Cancer

Treatment

Mr. Ahmed Kaskas

08:50 – 09:20 Are There Modifiable Risk Factors for Breast

Cancer? Highlighting the Importance of Exercise

Dr. Julie Gralow

09:20 – 09:40 AUBMC Outreach Program in Palliative Care

Dr. Rana Yamout

09:40 -10:00 Advocacy for Better Management of Patients with

Breast Cancer

Ms. Allison Dvaladze

10:00 – 10:20 Global Initiatives for Breast Cancer Awareness

Ms. Allison Dvaladze

10:20 – 10:40 Coffee Break

Participants who attend the ‘‘Oncology Nursing Symposium’’ will

receive 2.1 contact hours

The planning committee and the presenter(s) declare no conflict of

interest including financial interest in product or company; direct

research support, or other form of potential bias.

American University of Beirut Medical Center Nursing Services Clinical

and Professional Development Center is accredited with distinction as a

provider of continuing nursing education by the American Nurses

Credentialing Center's Commission on Accreditation.

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11:00-12:00 Medical-Nursing-NGO DEBATE

Chairs: Ms. Hanane Charara, Dr. Myrna Doumit, Ms. Allison Dvaladze,

Ms. Maria Farah & Dr. Julie Gralow

Panel: Ajialouna, ALISEP, Faire Face, Friends of MS, Lebanese Breast

Cancer Foundation, Makhzoumi Foundation, Mamdouha, May Jallad

Foundation, Pink Steps, Rabab Cancer Foundation, Revive, Zamanouna

& Zunta

12:00-13:00 LUNCH

13:00-13:45 Non-CME Lecture: Sponsored by an Unrestricted

Educational Grant from Roche

Updates of Immunotherapy in mTNBC

Dr. Nagi El Saghir

13:45-14:30 Non-CME Lecture: Sponsored by an Unrestricted

Educational Grant from Eli Lilly

Therapeutic Strategies for Hormonal Sensitive

Advanced Breast Cancer: Focus on CDK4/6 Inhibitors

Selection

Dr. Ahmad Awada

14:30 – 15:30 Advances in Systemic Therapy in Primary

Breast Cancer III Chairs: Drs. Zahera Fahed, Khaled Ibrahim, Ziad Salem & Adel Tabshy

14:30-14:50 Late recurrences and Escalating/ De-escalating

hormonal therapy

Dr. Julie Gralow

14:50-15:10 Escalating vs De-escalating Chemotherapy: When to

do What?

Dr. Ahmad Awada

15:10-15:30 Neoadjuvant Hormonal Therapy Revisited

Dr. Alaa Kandil

15:30-15:50 Coffee Break

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15:50 – 16:50 Special Lectures Chairs: Drs. Nizar Bitar, Roger Khater, Joseph Makdessi & Ghazi Nsouli

15:50-16:10: Special Lecture: Genomic Sequencing in Breast

Cancer and Possible Impact on Clinical Practice

Dr. Hatem Azim

16:10-16:30 Special Lecture: Recent Advances in the

Management of LCIS, and Briefly of DCIS

Dr. Mahmoud El-Tamer

16:30-16:50 Special Lecture: Neutropenia Prevention Guidelines

and Surprises with CDK4/6 Inhibitors

Dr. Matti Aapro

16:50-17:30 Tumor Boards Round Table Case Discussions II Case Discussions: Drs. Mattia Aapro, Hazem Assi, Sami Faddoul, Zahera

Fahed, Marwan Ghosn, Lara Nassar, Christine Salem

17:30-18:15 Non-CME Lecture: Supported by Novartis

Optimizing Management of HR+/HER2- Advanced

Breast Cancer

Dr. Matti Aapro & Dr. Nagi El Saghir

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Saturday, February 9, 2019

Conference Room: Rotana B

08:30-10:30 Systemic Therapy and Surgery Chairs: Drs. Ghassan Abu Sittah, David Atallah, Ghina Ghazeeri, Imad

Hajj, Dolly Nasr, Rabih Said & Ahmad Younes

08:30-08:50 Partial Mastectomy vs Double Mastectomies in

Young Women: Current Practices and Future

Prospects

Dr. Faek Jamali

08:50-09:00 Radiation Therapy after Breast Reconstruction

Dr. Zeina Ayoub

09:00-09:10 Breast Reconstruction after Radiation Therapy

Dr. Salim Saba

09:10-09:20 Planning Type of Mastectomy in the Setting of

Reconstruction

Dr. Eman Sbaity

09:20-09:40 Upfront Surgical Intervention versus Neoadjuvant

Chemotherapy

Dr. Mahmoud ElTamer

09:40-10:00 SLNB after Neo-adjuvant Therapy: When, How and

What If!

Dr. Jaber Abbas

10:00-10:20 Fertility Considerations and Challenges in BRCA+

Patients and BRCA Women Mutation Carriers

Dr. Hatem A. Azim, Jr.

10:20- 10:40 De-escalation of Surgery

Dr. Mahmoud AL-Masri

10:40-11:00 Coffee Break

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11:00-11:45 Tumor Boards Round Table Case Discussions III Case Discussions: Drs. Jaber Abbas, Hamdy AbdelAzim, Ahmad Antar,

Hatem A. Azim Jr, Serine Beydoun, Reine Fahed, Mohamd Haidar, Alaa

Kandil, Joseph Kattan, Hampig Kourie & Adel Tabshi

11:45-12:30: Non-CME Lecture: Sponsored by an Unrestricted

Educational Grant from Pfizer

Chair: Nizar Bitar

Changing Practice toward a comprehensive

management of HR+/HER2- metastatic Breast

Cancer: CDK4/6 inhibitors

Dr. Fady Farhat & Dr. Nagi Saghir

12:30-13:30 LUNCH

13:30-14:30 Monday Morning Clinic Session: Metastatic

Breast Cancer Chairs: Drs. Jospeh Kattan, Khaled Ibrahim & Ahmad Younes

13:30-13:50 Platinums, PARPi and Checkpoint Inhibitors in TNBC

Dr. Hamdy Azim

13:50-14:10 Anti-HER2 Therapy Updates in HER2-positive MBC

Dr. Hikmat AbdelRazeq

14:10-14:30 Management of Patients with Brain Metastasis

Dr. Ahmad Awada

14:30-16:00 New Research Oral Presentations and Prizes

for Best Posters (Abstracts/Posters will be on display throughout the conference)

Moderators/Selection Committee: Drs. Matti Aapro, Arafat Tfayli, Hatem

Azim, Ahmad Awada, Joseph Kattan, Nizar Bitar, Mahmoud El-Tamer,

Hamdi Azim, Nagi El Saghir

14:30 – 14:45 Prepectoral Direct-To-Implant Breast Reconstruction

with Complete ADM or Synthetic Mesh Coverage

REITSAMER Roland, KLAASSEN-FEDERSPIEL

Friederike, SIR Andreas; Breast Center Salzburg,

Paracelsus Medical University Salzburg, Austria

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14:45 – 15:00 Trends in Breast Cancer Staging at Diagnosis

Associated with Awareness and Screening Campaigns

in Lebanon

El Khoury Christine , El Asmar K, El Saghir NS,

Adib SM

American University of Beirut Medical Center,

Lebanon

15:00 – 15:15 Next-generation sequencing in familial breast/ovarian

cancer patients in Lebanon

Nadine El Jalkh, Ghadi Moubarak, Joe Ajami, Fadi

Gh Haddad, Roland Eid, Joseph Kattan, Marwan

Ghosn, David Atallah, Eliane Chouery Khoury,

Hampig Raphael Kourie

Faculty of Medicine , Saint Joseph University of

Beirut, Lebanon

15:15 – 15:30 BRCA mutation screening and patterns among high-

risk Lebanese subjects

Chantal Farra, MD, Christelle Dagher, MD, Rebecca

Badra, Miza Salim Hammoud, MD, Raafat

Alameddine, MD, Johnny Awwad, MD, Muhieddine

Seoud, MD, Jaber Abbas, MD, Fouad Boulos, MD,

Nagi El Saghir, MD, Deborah Mukherji*, MD

American University of Beirut Medical Center,

Lebanon

15:30 – 15:45 Demographics and Characteristics of young patients

≤40 years of age with breast cancer at AUBMC

Lana E. Khalil, Joud El Dick, Maya Charafeddine,

Johny Fares, Paul El Tomb, Nagi S. El Saghir

American University of Beirut Medical Center

15:45 – 16:00 Management and Outcome of breast cancer patients

≤40 years of age

Joud El Dick, Lana E. Khalil, Maya Charafeddine,

Paul El Tomb, Johny Fares, Nagi S. El Saghir

American University of Beirut Medical Center

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Saturday Morning Parallel Session

Level R: Topaz

09:00 – 12:30 Pharmacy Session (3 CE) Chairpersons: Dr. Ulfat Usta & Dr. Rony Zeenny

09:00 – 09:30 Updated Guidelines for Treatment of Advanced

HER2- Positive Breast Cancer in 2018

Ms. Maha Wazne

09:30 – 10:00 Cyclin-Dependent Kinase 4/6 Inhibitors in Breast

Cancer. How Can the Pharmacist Control the Safe Use

and Prescription of These New Medications?

Dr. Rhea Saad

10:00 – 10:30 Endocrine Therapy for Women with Breast Cancer:

Improving Adherence and Role of Clinical Pharmacist

Dr. Alissar Ghaddar

10:30 – 11:00 Controversies of the Role of PD-1/PD-L1 Inhibitors in

Breast Cancer

Dr. Myriam Bechwati

11:00 – 11:30 Coffee Break

11:30 – 12:00 Integrative Therapies During and After Breast Cancer

Treatment

Ms. Fatima Ismail

12:00 – 12:30 Gap Analysis Tool for USP800

Dr. Ulfat Usta

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Saturday Afternoon Parallel Session

Level C: Gefinor Meeting Room

14:00 – 16:00 NGO Workshop: NGO, Nursing, Oncology and

Advocacy

Facilitator: Ziad Hamdan

What do we know about the “Patient’s point of view” regarding the

diagnosis of breast cancer: Primary Breast Cancer, and Metastatic Breast

Cancer

Allison Dvaladze, MPH / Julie Gralow, MD,

Difficulties associated with diagnosis of Breast Cancer in Lebanon and

the Region

Speakers (Survivors, Advocates)

Patient’s Rights when diagnosed with Primary Breast Cancer

Patient’s Rights when diagnosed with Advanced Breast Cancer

Debate: Advocacy for Awareness, Early Detection, Screening, Better

Diagnosis, Better Treatment, Communication, Better Quality of Life