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CMASA2016Stellenbosch
DrDavidSwingler
02June2016
Acknowledgements
Overview� DSM-5
� History&development� What’snew� Concepts
� A‘speed-dating’surfthroughthedisordersWithparticularreferencetoconditionsofinteresttoCaseManagerssuchasADHD,Depression,BipolarDisorder,SubstanceUseandNeurocognitiveDisorders
DSM–abriefhistory� USA1840Census=idiocy&insanity� USA1880Census=7disorders� DSM-I(1952)AdolfMeyer/ICD-6=26� DSM-II(1968)‘reaction’withdrawn/ICD-8� DSM-III(1980)Newsystems/ICD-9� DSM-III-R(1987)� DSM-IV(1994)ApproximationwithICD-10� DSM-IV-TR(2000)� DSM-5(2013)ICD-11due2017/8
Organisa6onalStructure� HarmonizationwithICD-11
� IncludesICD-9-CMandICD-10-CMcodes� Developmental/Lifespanapproach
� SequentialOrderstartingwithNeurodevelopmentalDisorders,endingwithNeurocognitiveDisorders
� Dimensionalapproach� Spectra� Personality
TheMul6-AxialSystem–RIP� Nonaxialdocumentationofdiagnosis(formerlyAxisI,IIandIII)
� PrincipalDiagnosis:Theconditionchieflyresponsibleforcurrentpresentation.
� Followedbyothersinorderoffocusofattentionandtreatment.� Canuse“provisional”asaspecifierwherethereisastrong
presumptionthatfullcriteriawillbemet.� Recordimportantpsychosocialandcontextualfactors(formerlyAxisIV)usingICD-9-CMVcodesorICD-10-CMZcodes
� Disability(formerlyAxisV):GAFdropped.WHODAS2.0included‘forfurtherstudy’.� 36item,self-administeredscale.� Ratesdifficultyinspecificareasoffunctioninginpast30days.� Simpleorcomplexmethodsforcalculatingsummaryscore.
Chapters–1� NeurodevelopmentalDisorders� Schizophrenia-SpectrumandOtherPsychoticDisorders� BipolarandRelatedDisorders� DepressiveDisorders� AnxietyDisorders� Obsessive-CompulsiveandRelatedDisorders� TraumaandStressor-RelatedDisorders� DissociativeDisorders� SomaticSymptomandRelatedDisorders� FeedingandEatingDisorders� EliminationDisorders� Sleep-WakeDisorders� SexualDysfunctions
Chapters–2� GenderDysphoria� Disruptive,Impulse-Control,andConductDisorders� Substance-RelatedandAddictiveDisorders� NeurocognitiveDisorders� PersonalityDisorders� ParaphilicDisorders� OtherMentalDisorders� Medication-InducedMovementDisordersandOtherAdverseEffectsofMedication
� OtherConditionsThatMayBeaFocusofClinicalAttention
EmergingMeasuresandModels� AlternativeDSM-5ModelforPersonalityDisorders� Conditionsforfurtherstudy
� AttenuatedPsychosisSyndrome� DepressiveEpisodeswithShort-DurationHypomania� PersistentComplexBereavementDisorder� CaffeineUseDisorder� InternetGamingDisorder� NeurobehaviouralDisorderAssociatedwithPrenatalAlcoholExposure
� SuicidalBehaviorDisorder� Non-suicidalSelf-Injury
NeurodevelopmentalDisorders� MentalRetardationbecomesIntellectualDisability
� AutismSpectrumDisorderencompasses(social/behaviour)� Autism� Asperger’s� Rett’s� PervasivedevelopmentaldisorderNOS
NeurodevelopmentalDisorders� ADHD
� ‘Examplesaddedtofacilitateapplication’ofcriteria� ‘Oftenhasdifficultywaitingturn(e.g.waitinginline)’
� Ageofonsetrelaxedto<12(c.f.7years)� Subtypesreplacedwithspecifiers� ComorbiditywithAutismSpectrumnowallowed� ‘Adult’variantformalisedandlessrestrictivelyat5/9(c.f.6)
SchizophreniaSpectrumtechnicalchanges
� Schizophrenia*Spectrum&OtherPsychoticDisorders
� CriterionA� SZsubtypeseliminated� SchizoaffectiveDisorder� DelusionalDisorder� Catatonia� Schizotypal(Personality)Disorder
DSM-5‘Mood’Disorders� DSM-IVMoodDisorderssplitinto
� BipolarandRelatedDisorders� DepressiveDisorders
� Twonewandcontentiousdisorders� DisruptiveMoodDysregulationDisorder� PremenstrualDysphoricDisorder
BipolarandRelatedDisorders� BipolarIDisorder
� Definedbymania� Maniadefinedby
� Elevated/expansiveORirritablemoodfor7days(orhospitalised)� New:ANDincreasedgoaldirectedactivityORenergy� PLUS3(4)of7symptoms
� BipolarIIDisorder� RootedinMajorDepressiveEpisode/s� WithHypomanicEpisode/s,definedby
� Elevated/expansiveORirritablemoodfor4days(orhospitalised)� New:ANDincreasedgoaldirectedactivityORenergy� PLUS3(4)of7symptoms
DepressiveDisorders� MDE
� CriterionAunchanged� 5/9ofwhichatleastoneofdepressedmoodorlossofinterestorpleasurex2weeks
� MixedEpisodeexclusiondropped–‘specifier’� ‘Distress/Dysfunction’criterion‘elevated’CtoB� BereavementexclusionDROPPED
� Was2/12� Nowa‘Note’with‘clinicaljudgement’discretion
� Dysthymianow‘PersistentDepressiveDisorder’� Foldedinto‘chronicmajordepressivedisorder’
NewDepressiveDisorders!� DisruptiveMoodDysregulationDisorder
� ‘Toaddressover-diagnosisofBipolarDisorder<18years’� Temperoutbursts
� Severe,recurrent� Verbal&/orbehavioural� Outofproportioninintensity/durationtosituation/provocation� Inconsistentwithdevelopmentallevel� >3/week� Withbackgroundirritable/angrymood� Foratleastayear,withno3/12periodevent-free� Onset<10years� Firstdiagnosis6-18years
� ExclusionsandNotes…
NewDepressiveDisorders!� PremenstrualDysphoricDisorder
� A:Majorityofmenstrualcycles� Atleast5Sx(of11)fromB+Cbelow� Inlastweekpriortomenses� Improvewithinafewdaysofonsetofmenses
� Minimal/absentintheweekpostmenses
NewDepressiveDisorders!� 5of11symptomsforB&Ccombined� B:Atleast1of4
� Markedaffectivelability� Markedirritabilityorangerorinterpersonalconflicts� Markeddepressivemood/hopelessness/self-deprecation� Markedanxiety/tension/beingkeyedup/onedge
� C:Atleast1of7� Decreasedinterestinusualactivity� Difficultyconcentrating� Lethargy� Appetite,overeating,foodcravings� Sleepdisturbance:hyper-,insomnia� Overwhelmed,outofcontrol� Physicalsymptoms:breast,joint/muscle,‘bloating’,GOW
AnxietyDisorderstechnicalchanges
� SpecificPhobia&SocialPhobia� Panicattacks:nowaspecifiertoallDSM-5� PanicDisorderandAgoraphobiaun-linked� SeparationAnxietyDisorderandSelectiveMutismnowfindahomehere
ObsessiveCompulsive&RelatedDisorders
� Obsessive-CompulsiveDisordertheanchor� BodyDysmorphicDisordersmovein� New:
� HoardingDisorder� Excoriation(Skin-Picking)Disorder� Substance/Medicationinduced� DuetoAnotherMedicalCondition
� Trichotillomaniagets(Hair-PullingDisorder)clarifier
Trauma-&Stressor-RelatedDisorders
� Acute/PosttraumaticStressDisorder� Trauma‘moreexplicit’� ‘Disempowerment’requirementremoved� Threeclusters
� Re-experience� Avoidance/Numbing� Arousal
� Becomesfour,as#2split� Avoidance� Persistentnegativealterationincognition&mood
� Thresholdforchildren&adolescentslowered,now<6years
Soma6cSymptom&RelatedDisorders
DSM-5
AnorexiaNervosaDSMIV-TR:Refusaltomaintainbodyweightatoraboveaminimallynormalweightforageandheight(e.g.,weightlossleadingtomaintenanceofbodyweightlessthan85%ofthatexpected;orfailuretomakeexpectedweightgainduringperiodofgrowth)leadingtobodyweightlessthan85%ofthatexpected
DSM-5Restrictionofenergyintakerelativetorequirements,leadingtoasignificantlylowbodyweightinthecontextofage,sex,developmentaltrajectory,andphysicalhealth.Significantlylowweightisdefinedasaweightthatislessthanminimallynormalor,forchildrenandadolescents,lessthanthatminimallyexpected.
BulimiaNervosaDSM-5
A. Recurrentepisodesofbingeeating…B. Recurrentinappropriatecompensatory
behaviour…C. Thebingeeatingandinappropriate
compensatorybehaviorsbothoccur,onaverage,atleastonceaweekfor3months.
D. Self-evaluation…E. Thedisturbancedoesnotoccurexclusively
duringepisodesofAnorexiaNervosa.
BingeEa6ngDisorderA. Recurrentepisodesofbingeeating.Anepisodeofbingeeatingis
characterisedbybothofthefollowing:1.eatinglargeamounts…2.Asenseoflackofcontrolovereating…
A. Thebingeeatingepisodesareassociatedwith3ormoreofthefollowing:
1.eatingmuchmorerapidlythannormal2.eatinguntiluncomfortablyfull3.eatinglargeamountsoffoodwhennotfeelingphysicallyhungry4.eatingalone/feelingembarrassedbyhowmuchoneiseating5.feelingdisgustedwithoneself,depressed,orveryguiltyafterward
B. Markeddistressregardingbingeeatingispresent.C. Thebingeeatingoccurs,onaverage,atleastonceaweekfor3months.D. Thebingeeatingisnotassociatedwithrepeateduseofinappropriate
compensatorybehaviourasinbulimianervosaanddoesnotoccurexclusivelyduringthecourseofbulimianervosaoranorexianervosa
SLEEP-WAKE DISORDERS
DSM-5
Sleep-Wake Disorders (Previously Sleep Disorders)
DSM-IV-TR • Primary Insomnia (name changed) • Primary Hypersomnia (name changed) • Narcolepsy (same name) • Breathing-Related Sleep Disorder (divided into 3 disorders) • Circadian Rhythm Sleep Disorder (name
changed) • Nightmare Disorder (same name) • Sleep Terror Disorder (combined into Non
REM Sleep Arousal Disorder) • Sleepwalking Disorder (combined into Non
REM Sleep Arousal Disorder) • Sleep Disorders Related to Another Mental
Disorder (removed) • Sleep Disorders Due to a General Medical
Condition (removed) • Substance-Induced Sleep Disorder (name
change)
DSM-5 • Insomnia Disorder • Hypersomnolence Disorder • Narcolepsy • Breathing-Related Sleep Disorder - Obstructive Sleep Apnea Hypopnea - Central Sleep Apnea - Sleep-Related Hypoventilation • Circadian Rhythm Sleep-Wake Disorder • Non-Rapid Eye Movement Sleep Arousal
Disorder • Nightmare Disorder • Rapid Eye Movement Sleep Behaviour
Disorder • Restless Legs Syndrome • Substance/Medication-Induced Sleep
Disorder
Previously Substance-Related Disorders in DSM-IV
Substance Related and Addictive Disorders in DSM-5
Summary of Changes � Removal of the distinction between substance “abuse” and “dependence”
in DSM-IV � DSM-5: Criteria are provided for “substance use disorder” (SUD) – they
are a combination of “abuse” and “dependence” criteria from DSM-IV (that required a threshold of 1-2 for abuse, and 3 or more for dependence)
� The threshold for SUD in DSM-5 is two or more (of 11) � Severity of DSM-5 SUD is based on the number of criteria
Ø 2-3 criteria indicate a mild disorder Ø 4-5 criteria, a moderate disorder and Ø 6 or more a severe disorder
� “Cannabis- & caffeine-withdrawal” are new for DSM-5
Summary continued � Criteria groupings for Criterion A:
� Impaired control 1-4 � Social impairment 5-7 � Risky use 8-9 � Physiological i.e. tolerance and withdrawal 10-11
� Lastly… � Gambling Disorder included & Internet gaming is described � Behavioural addictions: “sex addiction”, “exercise addiction”
and “shopping addiction” are not included due to insufficient peer-reviewed evidence on diagnostic criteria
Substance-Induced Disorders � Remain the same for DSM-IV and DSM-5
SUBSTANCE INDUCED DISORDERS
Substance Intoxication and Withdrawal
Substance/Medication-Induced Mental Disorders
Neurocognitive Disorders of DSM-5
Major changes in DSM-5 DSM-IV-TR: Delirium, Dementia and Amnestic
disorders DSM-5: � Delirium retained � Dementia and Amnestic Disorders subsumed under
the newly named entity Major Neurocognitive Disorder – the term ‘dementia’ is not disallowed ‘where the term is standard’
� Addition of a new diagnostic category: “Minor Neurocognitive Disorder”
Delirium: main change DSM-IV
A. Disturbance of consciousness (i.e.. reduced clarity of awareness of
the environment) with reduced ability to focus, sustain or shift attention
DSM-5
A. Disturbance in attention (reduced ability to direct, focus, sustain and shift attention) and awareness (reduced orientation to the environment).
Neurocognitive Disorders Major vs Mild
� 1. Severity � Major and Mild NCDs exist on a spectrum of cognitive and functional
impairment
� 2. Independence � Relates to the individual's level of independence in everyday functioning � Mild NCD will have preserved independence � Major NCD will have impairment of sufficient severity so as to interfere
with independence � .
� 3. Usually a continuum with evolution � The distinction between Major and Mild NCD is inherently arbitrary, and
the disorders exist along a continuum.
Major Neurocognitive Disorder Diagnostic Criteria
� A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains (complex attention, executive function, learning and memory, language, perceptual-motor, or social cognition) based on: 1. Concern of the individual, a knowledgeable informant, or the clinician that there has been a significant decline in cognitive function; and 2. A substantial impairment in cognitive performance, preferably documented by standardized neuropsychological testing or, in its absence, another quantified clinical assessment.
� B. The cognitive deficits interfere with independence in everyday activities (i.e., at a minimum,
requiring assistance with complex instrumental activities of daily living such as paying bills or managing medications).
� C. The cognitive deficits do not occur exclusively in the context of a delirium
� D. The cognitive deficits are not better explained by another mental disorder (e.g., major depressive disorder, schizophrenia).
Mild Neurocognitive Disorder Diagnostic Criteria
• A. Evidence of modest cognitive decline from a previous level of performance in one or more cognitive domains (complex attention, executive function, learning and memory, language, perceptual motor, or social cognition) based on: 1. Concern of the individual, a knowledgeable informant, or the clinician that there has been a mild decline in cognitive function; and
2. A modest impairment in cognitive performance, preferably documented by standardized neuropsychological testing or, in its absence, another quantified clinical assessment.
• B. The cognitive deficits do not interfere with capacity for independence in everyday activities
(i.e., complex instrumental activities of daily living such as paying bills or managing medications are preserved, but greater effort, compensatory strategies, or accommodation may be required).
• C. The cognitive deficits do not occur exclusively in the context of a delirium.
• D. The cognitive deficits are not better explained by another mental disorder (e.g., major depressive disorder, schizophrenia).
Neurocognitive Disorders Domains Domain Tasks � Complex attention Major: diminished, multiple stimuli
Mild: takes longer -------------------------------------------------------------------------------------------------------- � Executive function Major: abandon complex activities
Mild: effort, multi-tasking -------------------------------------------------------------------------------------------------------- � Learning/memory Major: repeat self in conversation
Mild: recent events, occasionally repeats -------------------------------------------------------------------------------------------------------- � Language Major: anomia, paraphasias
Mild: naming, word finding -------------------------------------------------------------------------------------------------------- � Perceptual-Motor Major: can’t drive, navigation, confused at dusk
Mild: notes, maps, follows, effort -------------------------------------------------------------------------------------------------------- � Social cognition Major: insensitivity social contexts
Mild: subtle personality change, empathy
Major or Mild NCD: Specify… � Alzheimer’s disease � Frontotemporal lobar degeneration � Lewy body disease � Vascular disease � Traumatic brain injury � Substance/medication-induced � HIV infection � Prion disease � Parkinson’s disease � Huntington’s disease � Another medical condition / Multiple aetiologies
Notdealtwith� SexualDysfunctions� GenderDysphorias� ParaphilicDisorders� Disruptive,Impulse-Control,andConductDisorders� PersonalityDisorders� Medication-inducedMovementDisorders� V-codes� Conditionsforfurtherstudy
Q&A