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Biochemistry 2/e - Garrett & Grisham Copyright © 1999 by Harcourt Brace & Company 5.1 Proteins are Linear Polymers of Amino Acids

5.1 Proteins are Linear Polymers of Amino Acids

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5.1 Proteins are Linear Polymers of Amino Acids. The Coplanar Nature of the Peptide Bond. Six atoms of the peptide group lie in a plane!. “Peptides”. Short polymers of amino acids Each unit is called a residue 2 residues - dipeptide 3 residues - tripeptide 12-20 residues - oligopeptide - PowerPoint PPT Presentation

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Page 1: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

5.1 Proteins are Linear Polymers of Amino Acids

Page 2: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

Page 3: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

The Coplanar Nature of the Peptide Bond

Six atoms of the peptide group lie in a plane!

Page 4: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

Page 5: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

“Peptides”

• Short polymers of amino acids

• Each unit is called a residue

• 2 residues - dipeptide

• 3 residues - tripeptide

• 12-20 residues - oligopeptide

• many - polypeptide

Page 6: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

Page 7: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

Page 8: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

The sequence of ribonuclease A

Page 9: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

Page 10: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

Page 11: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

Page 12: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

Configuration and conformation are not the same

Page 13: 5.1 Proteins are Linear Polymers of Amino Acids

Biochemistry 2/e - Garrett & Grisham

Copyright © 1999 by Harcourt Brace & Company

The tetrameric structure of hemoglobin