Hydromorphone Brand and Generic names: Mechanism of Action Dosage forms available Strengths available Brand: Dilaudid Dilaudid –HP Hydromorph Contin Jurnista Palladone PMS-Hydromorphone Opioid analgesic Opioid agonist Act on CNS and GI tract Pain relief Tablet Controlled release capsules Prolonged release tablets IV, IM, SC solution 1,2,4,8, mg tablets 3,4.5,6,9,10,12,18,20,24,30mg controlled release capsules 4,8,16,32mg prolonged release tablets 1mg/ml syrup 1, 2, 10, 20, 50 mg/ml IV,IM,SC solutions Health Canada approved indication Drug Schedule Side Effects Therapeutic Success Relief of moderate to severe pain Narcotic (CDSA I) Hypotension Decrease bowel motility Drowsiness Dizziness Confusion Constipation Nausea Sedation Sweating vomiting pain relief Warfarin Brand and Generic names: Mechanism of Action Dosage forms available Strengths available Brand: Coumadin Warfilone Mylan-, Apo-, Novo-, Taro-, Teva-Warfarin inhibit synthesis of Vitamin K dependent clotting factors II, VII, IX, X Tablet 1,2,2.5,3,4,5,6,7.5,10 mg tablets

4 drug summary, lab 1, 342

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Drug monograph summaries of drugs for Pharm 342 lab

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Hydromorphone

Brand and Generic names: Mechanism of ActionDosage forms availableStrengths available

Brand: Dilaudid Dilaudid HP Hydromorph Contin Jurnista Palladone PMS-Hydromorphone Opioid analgesic Opioid agonist Act on CNS and GI tract Pain relief Tablet Controlled release capsules Prolonged release tablets IV, IM, SC solution 1,2,4,8, mg tablets 3,4.5,6,9,10,12,18,20,24,30mg controlled release capsules 4,8,16,32mg prolonged release tablets 1mg/ml syrup 1, 2, 10, 20, 50 mg/ml IV,IM,SC solutions

Health Canada approved indicationDrug ScheduleSide EffectsTherapeutic Success

Relief of moderate to severe painNarcotic (CDSA I) Hypotension Decrease bowel motility Drowsiness Dizziness Confusion Constipation Nausea Sedation Sweating vomiting pain relief

Warfarin

Brand and Generic names: Mechanism of ActionDosage forms availableStrengths available

Brand: Coumadin Warfilone Mylan-, Apo-, Novo-, Taro-, Teva-Warfarin inhibit synthesis of Vitamin K dependent clotting factors II, VII, IX, X and anticoagulant proteins C & S @ liver Tablet

1,2,2.5,3,4,5,6,7.5,10 mg tablets

Health Canada approved indicationDrug ScheduleSide EffectsTherapeutic Success

Prevention/ treatment of venous thrombosis and pulmonary embolism, atrial fibrillation with embolization, stroke, reinfarction Thrombophlebitis, congestive heart failure, myocardial infarction, cerebral embolismSchedule F Prescription Fatal/nonfatal bleeding from organs/tissues Paralysis, paresthesia, headache, chest/abdomen/joint/muscle pain, Necrosis of skin and other tissues Vomiting, diarrhea, infection, fever Reduction of blood clotting

Dextroamphetamine

Brand and Generic names: Mechanism of ActionDosage forms availableStrengths available

Brand: Adderall Dexedrine CNS stimulant Thought to block norepinephrine and dopamine reuptake Extended release capsules tablets

2.5,3.75,5,6.25,7.5,1.25,10,15,20,25,30 mg extended release capsules 5,10,15 mg tablet forms

Health Canada approved indicationDrug ScheduleSide EffectsTherapeutic Success

Treatment of ADHD (attention deficit hyperactivity disorder)Narcotic (CDSA I) Decrease/loss of appetite Stomach ache Insomnia Mood swings, weight loss Dry mouth Dizziness Headache Nervousness, anxiety, irritability Vomiting, nausea, diarrhea Increased attention (including ability to follow directions/finish tasks) Decrease impulsiveness and hyperactivity

Amlodipine

Brand and Generic names: Mechanism of ActionDosage forms availableStrengths available

Brand: Calcium Channel Blockers Caduet Norvasc Twynsta PMS/RAN/Accel-Amlodipine Apo/Auro/CO/Dom/GD/Jamp/Mar Mint/Myla/Phl/ratio/Riva/Septa Teva/Zym/Zadoz GD-amlodipine/atorvastatin Antihypertensive-antianginal agent Calcium ion influx inhibitor Selective inhibition of influx of calcium ions into vascular smooth muscle ad cardiac muscle, lowering contractile processes Rlaxes blood vessels Improve supply of blood and oxygen to heart Tablet

2.5,5,10 mg tablets

Health Canada approved indicationDrug ScheduleSide EffectsTherapeutic Success

Treatment of mild to moderate hypertension Management of chronic stable anginaSchedule F Prescription Headaches, dizziness Tiredness, extreme sleepiness Stomach pain, nausea Flushing, ankle/leg swelling Irregular heartbeat Reduced blood pressure Reduced chest pain (angina)