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3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and Radiology Computer Aided Diagnostics Laboratory, Massachusetts General Hospital Director, Tumor Imaging Metrics Core Dana Farber/Harvard Cancer Center Associate Professor of Radiology, Harvard Medical School

3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

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Page 1: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

3D Imaging in Radiology

Gordon J. Harris, Ph.D.

Director, 3D Imaging Service and Radiology Computer Aided Diagnostics Laboratory,

Massachusetts General Hospital

Director, Tumor Imaging Metrics CoreDana Farber/Harvard Cancer Center

Associate Professor of Radiology,Harvard Medical School

Page 2: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Acknowledgements

• Dr. James Thrall, Chairman Radiology, MGH• Dr. R. Gil Gonzalez, Chief Neuroradiology, MGH• 3D Imaging Service Staff: Jennifer McGowan,

Peggy MacWilliams, Sally Pinho, Kate Weiss, Joan Beaudoin, Julie Della Monica, Jane Kelley, Fresnel Josaphat, Anthony Ranson, Shirley Thurston, Jonathan Lombardi, Trinity Urban, Dierdre Pierce, Joyce Miller, Bill Hanlon, Jon DeVries, Hiro Yoshida, Wenli Cai, Janne Nappi, Vadim Frenkel

Page 3: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory
Page 4: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

3D Imaging Overview

• Goals of 3D Imaging Service• 3D Imaging and Clinical Benefits• 3D Imaging Service at MGH

– Clinical Exam Volume– Staff– Workflow

• 3D Billing and Reimbursement

Page 5: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Goals of 3D Clinical Service

• Integrate Computer Aided Diagnosis (visualization, quantitative analysis) into routine clinical workflow

• Bridge research and clinical applications to migrate new technologies into clinical practice

Page 6: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

3D ImagingAxial images are ‘stacked’ into a three-

dimensional volume

Stacked Axial Slices 3D Volumesjn/MGH

Page 7: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Image Processing Techniques• Multi Planar Reconstruction (MPR / MPVR)

• Oblique and Curved Reformat

• MIP (Maximum Intensity Projection)

• Shaded Surface Display

• Volume Rendering

• Endoluminal Views (Virtual Colon, Bronch, Vessels)

• Functional Imaging

• CADx: Segmentation, Quantitation

Page 8: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

2.5 mm

1.25 mm

Page 9: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

MIP Rendering• Maximum Intensity Projection

• Displays the pixels of highest intensity along a ray

• Useful for vascular anatomy

sjn/MGH

Page 10: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Orthopaedics: Volume Rendering (VR)

Page 11: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Neurovascular Imaging: VR Curved

Page 12: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

CT Bronchography: Endoluminal See-Through

Page 13: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Neurovascular CTA/MRA: VR MIP

Page 14: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Cardiac CTA: Normal 3˚CABG

Page 15: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Functional Analysis

- Image pixels derived froma function of changingsignal over time

•CT/MR Perfusion•fMRI

Page 16: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

FunctionalCT Perfusion

CBV CBF MTT

Page 17: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Functional MR Perfusion

CBV CBF MTT

Page 18: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Functional MRI (fMRI)

Page 19: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Computer-Aided Segmentation

Page 20: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Total Volume = 1551.8cc’s

Semiautomated segmentationVirtual Hepatectomy

Page 21: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Left Lobe segment 316.91 cc’s

Virtual Hepatectomy

• Define surgical plane

• Sufficient volume for regeneration

Transplant segment

Page 22: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

CADx: Automated Segmentation: VR MIP

Page 23: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

CADx: Brain Tumor Volume

Page 24: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory
Page 25: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

BRIGHT DARK TOTAL

126.92 22.696 149.62

Tumor Volume

Page 26: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

CADx: Breast ImagingMR w/ registration/subtractionR2 Mammogram Image Check

QuickTime™ and a decompressor

are needed to see this picture.

Page 27: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

QuickTime™ and aMicrosoft Video 1 decompressorare needed to see this picture.

CT Angiography (CTA)

Page 28: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

CT Urography (CTU)

CTA/CTU: non-invasive replacement-- Catheter Angiography PLUS IVP

Page 29: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Clinical Benefits of 3D Radiology

• More comprehensive and realistic views of patient

• Faster, more confident diagnoses and treatment planning decisions

• Reduced need for exploratory surgery

• Minimize surgical invasiveness and operating room time; reduced damage to healthy tissue

Page 30: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

3D Imaging Service at MGH

• Clinical computer visualization for routine clinical use; 3D on request.

• Fast turnaround, full-time technologists

• Full integration with hospital PACS and information, billing systems

• Currently, over 2500 cases processed per month

Page 31: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

3D Imaging Service Staff (13 FTEs)

• Director• Operations Manager• Administrator/Billing Coordinator• Technical Staff (2)• 3D Technologists (5)• Image Analysis Specialists (2)• 3D Ultrasound Technologist

Page 32: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

3D Imaging Service Hardware and Software at MGH

5 GE Advantage Workstations5 Vital Images Vitrea WorkstationsTera Recon Aquarius Workstation and NetServer2 Voxar Workstations2 LINUX Computers with MedX/VolumePro for fMRIMirada Fusion7D Workstation for image registration3 GE LogiqWorks for 3D Reconstruction of USAGFA PACS Service Station, and RadWorks PACSMaterialize SimPlant/Master for Dental Implant PlanningMMS Preview LINUX ServerLINUX DICOM Server, 7 PCs, 2 Macs

Page 33: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory
Page 34: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

MGH 3D IMAGING SERVICE:Daily Average Volume by Month

0

20

40

60

80

100

120

140

160

FY' 99 2.3 4.7 7 6.9 8.7 9.2 10.9 10

FY' 00 16.9 18.4 16.3 17.4 17.6 17.3 22 24.4 24.1 25.4 26.6 30.3

FY'01 32.5 32.6 31.1 29.9 30 34.4 34.6 28.9 31.6 43.6 35.2 37.5

FY'02 39.1 40.2 40.7 45.5 47.6 46.7 51.2 55.3 49.5 55.5 52.2 62.4

FY'03 68.4 78.9 76.3 78.5 77.2 83.1 78.5 86.6 91.5 82.9 80.1 79.0

FY'04 82.7 84.3 75.6 88.7 90.7 90.3 89 102.5 99.3 92.5 102.4 110.6

FY'05 110.9 106.1 98 101.6 108.4 106.3 113.2 118.4 110.5 114 103 120.6

FY'06 122.6 120.4 114.7 122.8 116.8 115.6 110.8 126.9 129 126.2 125 138

October November December January February March April May June July August September

Page 35: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

3D Imaging Service Clinical Workload at MGH

• 120 Exams per day processed– 30 per day MR Angiography (MRA)– 30 per day CT Angiography (CTA)– 30 per day other CT and MR exams– 30 per day Ultrasound

• Radiology Sub-Specialty breakdown– 50% Neuroradiology– 20% Vascular Radiololgy– 30% GI/GU, Chest, Breast, Bone, Pedi Radiology

• 20% of all MR,US Exams: ~16,000/80,000 per year• 10% of all CT Exams:

~ 12,000/120,000 per year

Page 36: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Original

Original

AGFA/PACS AGFA/PACS

Radiologist View StationRadiologist View Station

AMICAS WEB ServerAMICAS WEB Server

Original Scan

PACS GatewayPACS Gateway

CT/MR scannerCT/MR scanner

Ori

gina

l

Referring PhysicianReferring Physician’’s Desktops DesktopPC WEB BrowserPC WEB Browser

Page 37: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Ori

gina

l

Referring PhysicianReferring Physician’’s Desktops DesktopPC WEB BrowserPC WEB Browser

3D

Referring PhysicianReferring Physician’’s Desktops DesktopPC WEB BrowserPC WEB Browser

Original

Original

AGFA/PACS AGFA/PACS

Radiologist View StationRadiologist View Station

AMICAS WEB ServerAMICAS WEB Server

3D

3D

AGFA/PACSAGFA/PACS

Radiologist View StationRadiologist View Station

AMICAS WEB ServerAMICAS WEB Server

CT/MR scannerCT/MR scanner

Original Scan

PACS GatewayPACS Gateway

3D

3D Workstation3D Workstation

Ori

gina

l

Page 38: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

CombineCombineClinical Need Clinical Need

withwithProductsProducts

BillingBillingCodesCodes

PACSPACSRoutingRouting

ScanScanProtocolsProtocols

3D3DProtocolsProtocols

ReferralReferralProtocolsProtocols

Implement

OR

Identify

Clinical Clinical NeedNeed

EvaluateEvaluateClinical Clinical ProductsProducts

NewNewProductProduct

EvaluateEvaluateClinical Clinical

NeedNeed

BillingBilling ComplianceComplianceClinicalClinicalWorkflowWorkflow

Page 39: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Imaging Protocols• Part of departmental scan protocols

• Billable Service

Page 40: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

• CPT # 76377(6) for 3D reconstruction– Billed in association with Primary CT/MR/US code

• Requirements for Reimbursement:– Part of Departmental Protocol, Physician Notification– By specific request from physician– Positive finding by radiologist, requiring further views– Processing on FDA approved software

Billing and Reimbursement: 3D Add-on Code

Page 41: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

• TC component -- if billed by Hospital:– Billed under HOPPS, APC 282– Reimbursed by Medicare at $95 (Nat’l Avg, 2007)

• TC component -- if billed by non-hospital:– Billed under MPFS (RVU-based)– Reimbursed by Medicare at ~$113 (Nat’l Avg, 2007)– Used if non-hospital imaging center, or 3D done by P.O.– Split or Global billing

• Prof. (-26) reimbursement ~$41

Billing and Reimbursement: 3D Add-on Code -- How to bill:

Page 42: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

• Billed prior to 2001 with CPT # 76375• New CPT codes in 2001 for CTA• CTA and MRA now include post-processing

– 3D processing no longer separate charge for CTA/MRA

• PROBLEM: CTA was reimbursed same as CT– No additional reimbursement for added time, equipment

• We have achieved changes from Medicare– new APC in 2003 for CTA (need to improve charges)– Increased 2003 RVU TC reimbursement

Billing and Reimbursement: CT and MR Angiography (CTA/MRA)

Page 43: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Billing and Reimbursement: CTA Problems Continue!!

• Even with CMS changes in CTA, problems remain• APC Reimbursement set relative to claims data• Only 40% of hospitals charge more for CTA than

CT!! (Source: 2001, 2002 CMS claims data)• Most hospitals charge less for CTA than CT!!

- CMS example: Hospital Y charged ~4X for CT ($1,392) vs. CTA ($377)

• Impact: Reimbursement for CTA less than CT

Page 44: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

• Prior to 2001, CTA was equal to CT PLUS 3D!• 2001 reimbursement was $114 higher for CTA• Hospitals must set charges accordingly

– Review Chargemaster and revise CTA charges relative to CT

• Charges for CTA should reflect sum of charges for CT (w/&w/out) plus charges for 3D (76375)

• Example: If CT charge is $1200, and if 3D charge is $400, CTA charge should be $1600

Billing and Reimbursement: CTA Charge Recommendations

Page 45: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Impact of New Technologies on Radiology

3D Visualization enables faster, more confident diagnoses and treatment decisions

Quantitative analysis and CADx can provide more accurate, reliable treatment planning, staging, and assessment

Improved patient care, increased clinical confidence, reduced time, cost, and invasiveness

Page 46: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Vision for the Future of 3D and CADx Services

Scale Up Services to Support Needs of Many Hospitals and Imaging Centers

Most Facilities Lack Resources and Expertise to Implement In-House Solution

Off-Hours Coverage Difficult

Use Advances in Networking and Communications to Centralize Services

Expand CADx and 3D Services

Advanced Core Lab

Page 47: 3D Imaging in Radiology - · PDF file05.05.2013 · 3D Imaging in Radiology Gordon J. Harris, Ph.D. Director, 3D Imaging Service and . Radiology Computer Aided Diagnostics Laboratory

Thank you!!!Any Questions?