2015-2016 Annual Report - smhs.gwu.edu · 2015-2016 ANNUAL REPORT ... Cynthia Tracy, MD - Electrophysiology Fellowship ... Aung Myint, DO. VA RESIDENT OF THE YEAR Paul Blair, MD

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DEPARTMENT OF MEDICINE2015-2016 Annual Report

The GW MedicalFaculty Associates

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DEPARTMENT ANNUAL REPORTAs the Eugene Meyer Professor and Chair of the Department of Medicine, I am fortunate to work with an amazing group of talented physicians, researchers, administrators and students. Our growth in almost every area has been nothing short of extraordinary and I wanted this year to be able to highlight some of these accomplishments. I was stunned and excited when starting this mission to realize just how much we have to showcase. We have increased our productivity in every area of importance; from clinical to educational to research to philanthropy.

Our clinical charges have grown from just over $85 million to over $125 million in the last seven years. The total dollars in grant money from federal, foundational and pharmaceutical sources has surpassed the $6 million mark, and many of our young, new research oriented faculty secured their first source of funding this past year. This could not have been accomplished without the assistance and support from Dr. Bob Miller, Senior Associate Dean for Research at the Medical School.

Our Department has played a major role in implementing the new Medical School curriculum and in helping the School of Medicine achieve an excellent report from the LCME. We have also contributed to the Hospital’s expansion with the success of both the Kidney Transplant Service as well as the TAVR program. We achieved expansion of the Hospital’s patient population through the One-Call service, of which the Department through our Hospitalists take the majority of transfers.

Our commitment to diversity is reflected in our house staff and faculty. With every recruitment we must continue to strive to mimic our multi-cultural community of Washington, DC.

We will continue to make advances in areas from innovative research to health disparities; from clinical public health to new payment models. It is exciting to observe our Cancer Center begin to recruit and expand. This joint effort with the Hospital and the University is indicative of the great things that we can accomplish together.

Our three main objectives remain clear. We must continue to provide the highest quality of patient care, educate the next generation of physicians, and provide an atmosphere for innovative research in areas from basic science to medical education. Unlike most professions, our work is never done.

Alan G. Wasserman, MD, FACC, MACPEugene Meyer Professor Chairman, Department of Medicine

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2015-2016 ANNUAL REPORTThe GW Medical Faculty Associates Department of Medicine, Faculty and Leadership

Alan G. Wasserman, MD, FACC, MACPChairman of the Department of MedicineEugene Meyer Professor of Medicine

Gary L. Simon, MD, PhD, MACPVice Chairman, Department of MedicineWalter G. Ross Professor of Medicine and of Microbiology & Tropical MedicineDirector of the Division of Infectious Diseases

Delores Jewell, RN, MSNAssociate Chair for Finance and Operations

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GENERAL INTERNAL MEDICINEApril Barbour, MD, MPH, FACPAssociate Professor of MedicineDirector, Division of General Internal MedicineDirector, Primary Care Residency Program

GASTROENTEROLOGYMarie Borum, MD, EdD, MPHProfessor of MedicineDirector, Division of Gastroenterology

GERIATRICS/PALLIATIVE CAREKatalin Roth, MD, JDAssociate Professor of MedicineDirector of the Division of Geriatrics and Palliative Medicine

ALLERGYDaniel Ein, MDClinical Professor of MedicineDirector, Allergy & Sinus Center

CARDIOLOGYRichard Katz, MDBloedorn Professor of CardiologyDirector, Division of CardiologyDirector, Cardiovascular Institute

ENDOCRINOLOGYJoshua Cohen, MDProfessor of MedicineInterim Director, Division of EndocrinologyDirector, Diabetes Center; Director, Thyroid Center

DIVISION DIRECTORS

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HEMATOLOGY/ONCOLOGYEduardo Sotomayor, MDProfessor of MedicineDirector, GW Cancer CenterDirector, Division of Hematology/Oncology

HOSPITAL MEDICINEJames Gehring, MDAssistant Professor of MedicineInterim Director, Division of Hospital Medicine

INFECTIOUS DISEASESGary L. Simon, MD, PhD, MACPVice Chairman, Department of MedicineWalter G. Ross Professor of Medicine and of Microbiology & Tropical MedicineDirector, Division of Infectious Diseases

PODIATRYMichael Stempel, DPM, FACFASChief, Division of PodiatryAssistant Professor of Medicine, Assistant Professor of SurgeryDirector of Podiatry Center

DIVISION DIRECTORS

PULMONARYGuillermo Gutierrez, MD, PhDProfessor of Medicine, Anesthesiology and Engineering and Applied SciencesDivision of Pulmonary, Critical Care and Sleep Disorders

RENAL AND HYPERTENSIONDominic Raj, MD, DM, DNB, FASN, FACPProfessor of Medicine and of Epidemiology and Biostatistics and of Biochemistry and Molecular BiologyDirector, Division of Renal Disease and Hypertension

RHEUMATOLOGYVictoria Shanmugam, MD, MRCPDirector, Division of RheumatologyAssociate Professor of Medicine

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ADMINISTRATIVE MANAGERS

Melanie Bossi, MPAAssistant Director of Clinical Research

Hawanya Brock, BAAdministrative Support Manager

Cristina BurgosExecutive Associate

Donna Embersit, BSAssociate Director of Clinical Research

Jocelyn HutchinsonAccounting Specialist

Shawn Kimbro, RST, RPSGT, CSESleep Center Manager

Royette Leatham, MBA, LLBFaculty Affairs Administrator

Mary Claire MarconiDirector of Contact Center Operations & Special Projects

Delphine McDowellRevenue Cycle Manager

Lara Mounir, MHSASpecial Projects Coordinator

Ann Nichols, MHSA, CPCDirector of Operations for Hematology/Oncology

Erwin Osborn, MHSANon-Invasive Cardiology Manager

Shirley Overman, MSN, RNNurse Manager

Valorie SimmonsFinance Manager

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UNDERGRADUATE MEDICAL EDUCATION LEADERSHIP

Dr. Robert Jablonover3rd year Primary Care Clerkship Director

Dr. Chavon OnumahAssistant Primary Care Clerkship Director

Dr. Sara Wikstrom3rd year Medicine Clerkship Director

Dr. Shant AyanianMedicine Assistant Clerkship Director

Dr. Farida Izzi 4th year Medicine Acting Internship director

Dr. Adam Possner/Dr. Anna Mclean effective 8/1/2016Clinical Apprenticeship Program Director &Longitudinal Primary Care Clerkship Coordinator

Dr. Andrea FloryClinical Skills & Reasoning Theme Director

Dr. Jim BlattProfessional Development Theme Director

Dr. Katalin RothEthics Theme Director

Dr. David PopielPublic Health Theme Director

Dr. W. Scott SchrothAssociate Dean for Administration

Dr. Matthew MintzAssistant Dean, Pre-Clinical Education

Dr. Katherine ChretienAssistant Dean for Student Affairs

Dr. Lawrence “Bopper” DeytonSenior Associate Dean for Clinical Public Health

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3rd YEAR RESIDENTS

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GRADUATE MEDICAL EDUCATION LEADERSHIP

Dr. Jillian CatalanottiDirector of Internal Medicine Residency Programs

Dr. April BarbourDirector, Primary Care Residency; Associate Program Director of Internal Medicine

Dr. Michael CzarneckiAssociate Program Director of Internal Medicine Fellowship Programs

Dr. Sheena P. KhuranaAssociate Program Director, Medical Clinic

Dr. Anne CiolettiAssistant Director, Primary Care Residency; Associate Program Director of Internal Medicine

Dr. Nupur MehtaAssociate Program Director of Internal Medicine

Dr. Jalil AhariAssociate Program Director of Internal Medicine

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FELLOWSHIP PROGRAM DIRECTORS

CARDIOLOGYAllen Solomon, MD - General Cardiology FellowshipRamesh Mazhari, MD - Interventional Cardiology FellowshipCynthia Tracy, MD - Electrophysiology Fellowship

ENDOCRINOLOGYJoshua Cohen, MD/ Jill Paulson, MD - effective 7/1/2016

GASTROENTEROLOGYMatthew Chandler, MD

GERIATRICSElizabeth Cobbs, MD - GeriatricsKaren Blackstone, MD - Hospice/Palliative CareMikhail Kogan, MD - Integrative Medicine

HEMATOLOGY/ONCOLOGYImad Tabbara, MD

INFECTIOUS DISEASESAfsoon Roberts, MD

PULMONARYJalil Ahari, MD

RENALSamir Patel, MD/ Scott Cohen, MD - effective 7/1/2016

RHEUMATOLOGYRodolfo Curiel, MD

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EMERITUS PROFESSOR FACULTY

Charles Abrams, MD, Associate Clinical Professor Emeritus

Rochelle Bader, MD, Adjunct Associate Professor Emeritus

Kenneth Becker, MD, Professor Emeritus

Philip Birnbaum, MD, Professor Emeritus

Warren Brill, MD, Clinical Professor Emeritus

Paul Chang, MD, Clinical Professor Emeritus

Allen Ginsberg, MD, Professor Emeritus

Kenneth Goldstein, MD, Clinical Professor Emeritus

David Goodman, MD, Clinical Professor Emeritus

Richard Kaufman, MD, Clinical Professor Emeritus

Robert Keimowitz, MD, Professor Emeritus

Arnold Lear, MD, Clinical Professor Emeritus

Allen Mondzac, MD, Clinical Professor Emeritus

Frederick Meyers, MD, Associate Clinical Professor

Frederick Rickles, MD, Clinical Professor Emeritus

Jorge Rios, MD, Professor Emeritus

Allan Ross, MD, Professor Emeritus

Geraldine Schechter, MD, Professor Emeritus

Paul Schlein, MD, Clinical Professor Emeritus

W. Scott Schroth, MD, Associate Professor Emeritus

Omega Silva, MD, Clinical Professor Emeritus

David Simon, MD, Clinical Professor Emeritus

P. Jacob Varghese, MD, Professor Emeritus

Manuel Velasquez, MD, Clinical Professor Emeritus

Lowell Weiss, MD, Clinical Professor Emeritus

Patience White, MD, Professor Emeritus

Robert Wilkinson, MD, Professor Emeritus

James Cooper, MD, Clinical Professor Emeritus

Stanley Talpers, MD, Associate Clinical Professor Emeritus

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PROMOTIONS

Congratulations to the following Full-Time Medicine Faculty on their academic promotions effective July 1, 2015: PROFESSORLakhmir Chawla, MD, Professor of Medicine (VA)Jehan El-Bayoumi, MD, Professor of MedicineCarlos Palant MD, Professor of Medicine (VA)

ASSOCIATE PROFESSORMohammed Aamir Ali MD, Associate Professor of MedicineJillian Catalanotti MD, Associate Professor of MedicineDanielle Davison, MD, Associate Professor of Medicine and AnesthesiologyVivek Jain, MD, Associate Professor of MedicineRaya Kheirbek, MD, Associate Professor of Medicine (VA)Marc Siegel, MD, Associate Professor of Medicine

ASSOCIATE CLINICAL PROFESSORBonita Coe, MD, Associate Clinical Professor Robert Kruger, MD, Associate Clinical ProfessorMia Marcus, MD, Associate Clinical Professor

LIMITED SERVICE MEDICINE FACULTYRichard Kaufman, MD, Clinical Professor EmeritusCharles Abrams, MD, Associate Clinical Professor Emeritus of MedicineElizabeth Wheaton, MD, Associate Clinical Professor Frederick Parker, III, MD, Associate Clinical Professor Gary Koritzinsky, MD, Associate Clinical Professor Mahnaz Momeni, MD, Associate Clinical Professor Homan Wai, MD, Assistant Clinical Professor Rebecca Witt, MD, Assistant Clinical Professor Anne Linton, MS (Librarian), Adjunct Associate Professor

EMERITUS STATUS EFFECTIVE: 7/1/2016James K. Cooper, MD, Clinical Professor EmeritusDavid Goodman, MD, Clinical Professor EmeritusFrederick Rickles, MD, Clinical Professor Emeritus in ResidenceW. Scott Schroth, MD, Associate Professor EmeritusManuel Velasquez, MD, Clinical Professor Emeritus in Residence

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MEDICINE FACULTY OF THE YEARNupur Mehta, MD

CLINIC ATTENDING OF THE YEARChad Henson Martins, MD

VA ATTENDING OF THE YEARMatthew Tuck, MD

FAIRFAX ATTENDING OF THE YEARMeena Raj, MD

FELLOW OF THE YEARAlex Cho, MD

JORGE RIOS RESIDENT OF THE YEARAung Myint, DO

VA RESIDENT OF THE YEARPaul Blair, MD

FAIRFAX RESIDENT OF THE YEARMitali Mehta, MD

“ICU” RESIDENT OF THE YEARKatie Cramer, MD

INTERN OF THE YEARHind Rafei, MD

PRELIMINARY INTERN OF THE YEARSumeet Gupta, MD

ANNUAL SUSAN HASSELQUIST AWARD Aneesha Hossain, MDThis award is presented to a resident who exemplifies compassionate care combined with clinical and diagnostic excellence

END OF THE YEAR AWARDS

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AOA INDUCTION: ALPHA OMEGA ALPHA MEDICAL HONOR SOCIETYDr. Alan Wasserman, CouncilorDr. Angelike Liappis, Secretary - Treasurer

HOUSESTAFF INDUCTEESBetsy Kidder, MD, PhD, PGY2, Internal Medicine resident, Department of MedicineErin Vipler, MD, Internal Medicine Chief ResidentJose Lucar, MD, Infectious Diseases Fellow

FACULTY INDUCTEESDr. Jalil Ahari, Assistant Professor of Medicine Dr. J. Keith Melacon, Professor of Surgery and Chief, Division of Transplantation ALUMNI INDUCTEEDr. Lawrence R. Deyton, Professor of Medicine and of Health Policy, Senior Associate Dean for Clinical Public Health

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MASTER TEACHER LEADERSHIP DEVELOPMENT PROGRAM GRADUATIONJune 15th- Weingold Conference Center

DEPARTMENT OF MEDICINE GRADUATESChavon Onumah, MD, MPH- General Internal MedicineNora Taylor, MD- RheumatologySara Wikstrom, MD- Hospital Medicine

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TOP DOCS

Congratulations to all the physicians below from the Department of Medicine for being selected to Washingtonian’s Top Docs 2015:

ALLERGYDaniel EinJanine Van Lancker

CARDIOLOGYBrian ChoiRichard KatzScott ShapiroAllen SolomonCynthia TracyAlan Wasserman

CARDIOLOGY INTERVENTIONALRamesh MazhariChristian NagyJonathon Reiner

ENDOCRINOLOGYSuzanne AdlerJoshua CohenMichael IrwigJill Paulson

GASTROENTEROLOGYM. Aamir AliShowkat BashirMarie BorumSands IraniAntoinette SaddlerSteven Zeddun

GERIATRICSElizabeth CobbsDanielle DobermanRobert JayesChristina PuchalskiKatalin Roth

INFECTIOUS DISEASESDavid ParentiAfsoon RobertsMarc SiegelGary SimonCarmelita Tuazon

INTERNAL MEDICINESharon BaratzApril BarbourJillian CatalanottiJehan El-Bayoumi (Gigi)Robert JablonoverParvinder Sheena KhuranaMatthew MintzBrad MooreDavid PopielAdam PossnerPaul Silver

NEPHROLOGYScott CohenAshte CollinsSusie LewSamir PatelDominic Raj

ONCOLOGY/HEMATOLOGYRebecca KaltmanFrederick RicklesRobert SiegelImad Tabbara

PULMONOLOGYJalil AhariMorgan DelaneyGuillermo GutierrezVivek Jain

RHEUMATOLOGYRodolfo CurielMandana HashefiNora Taylor

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ENDOWED GRAND ROUND LECTURES

October 1st 2015: Understein Memorial Lecture -“ Future of Medical Therapeutics”- Dr. Elliott Antman, Professor of Medicine, Associate Dean, Clinical and Translational Research, Harvard Medical School, Senior Physician, Cardiovascular Medicine, Brigham and Women’s Hospital

May 5th 2016: Zimmerman Endowed Lecture - “Non-alcoholic Steatohepatosis”- Dr. Zobair Younossi, Professor of Medicine, Virginia Commonwealth, University, Inova Campus, Vice President, Research for Inova Health System, Executive Director, Center for Liver Diseases, Inova Fairfax Hospital

June 2nd 2016: Wipplinger Lecture- Best of Chairman’s Rounds, Dr. Maggie Gloria, PGY 3, and Dr. Paul Blair, PGY 3

June 16th 2016: Tamagna Endowed Lecture –“Preeclampsia: from Science to Medicine”- Dr. Ravi Thadhani, Professor of Medicine, Harvard Medical School, Executive Director, Clinical Trials Office at Partners Health Care, Chief of Nephrology Division, Massachusetts General Hospital

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FRONTIERS OF MEDICINEQuarterly lecture series for the GW and DC community sponsored by the School of Medicine and moderated by Dr. Alan Wasserman

“WHAT YOU NEED TO KNOW ABOUT CANCER PREVENTION AND SCREENINGS” - WEDNESDAY, OCTOBER 14, 2015

Thomas W. Jarrett, MD, Professor and Chair, Department of Urology

Rachel F. Brem, MD, FACR, FSBI, Vice Chair of Radiology, Director, Breast Imaging and Intervention Center

Marie L. Borum, MD, EdD, MPH, Professor of Medicine Director, Division of Gastroenterology and Liver Diseases

Moderator: Alan Wasserman, MD, FACC, MACP, Chairman, Department of Medicine, Eugene Meyer Professor of Medicine

While maintaining a healthy lifestlye and avoiding risk factors are key to cancer prevention, early detection is one of the most important means to control cancer. That is why regular screenings – checking for cancer before there are signs or symptoms – are crucial to detecting cancer at an early stage, thus increasing the likelihood of successful treatment. Join us as GW physicians Thomas W. Jarrett, M.D., Rachel F. Brem, M.D., FACR, FSBI, and Marie L. Borum, M.D., Ed.D., M.P.H., explain how prostate screenings, mammographies, colonoscopies and other gastrointestinal screenings can find problems early and even save lives.

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FRONTIERS OF MEDICINE

“ATTACKING CANCER ON MULTIPLE FRONTS: UNCOVERING NEW PATHS IN CANCER RESEARCH” - TUESDAY, DECEMBER 1, 2015

Eduardo M. Sotomayor, M.D., Director, GW Cancer Center, Professor of Medicine

Edward Seto, Ph.D., Associate Director for Basic Sciences, GW Cancer Center Professor of Biochemistry and Molecular Medicine

Moderator: Alan Wasserman, MD, FACC, MACP, Chairman, Department of Medicine, Eugene Meyer Professor of Medicine

While the toll of death and suffering caused by cancer is significant, important new breakthroughs in cancer research are changing the way we treat this group of diseases. Join us as our experts from the new GW Cancer Center reveal the innovative new ways cancer is being targeted and treated.

Eduardo M. Sotomayor, MD, Director of the GW Cancer Center and Professor of Medicine, will explain how harnessing the power of the immune system is providing major breakthroughs in cancer treatment. He will also discuss using engineered microorganisms as potential therapies.

Edward Seto, PhD, Associate director for basic sciences at the GW Cancer Center and Professor of Biochemistry and Molecular Medicine, will discuss how the new understanding of tumor cells through genetics and epigenetics is leading to more potent and more selective anticancer treatments.

They will both discuss how the convergence of these two areas will impact cancer care in the future.

“HEALTHY AGING PART IV: MAINTAINING A HEALTHY NECK AND BACK” – TUESDAY, APRIL 5, 2016

Anthony Caputy, MD, FACS, Chair, Department of Neurological Surgery, Rizzoli Professor of Neurological Surgery

Raj Rao, MD, Chair, Department of Orthopaedic Surgery, Professor of Orthopaedic Surgery and Neurosurgery

Moderator: Alan Wasserman, MD, FACC, MACP, Eugene Meyer Professor of Medicine, Chairman, Department of Medicine and Chairman, Council of Clinical Chairs

Among the most common bodily complaints that come with aging is pain of the back and neck. As we get older, the discs that cushion the spine’s vertebrae undergo normal wear and tear, causing loss of flexibility, stiffness and pain.

While we can’t prevent aging, there are steps we can take to slow and minimize these negative effects. Learn more about maintaining a healthy neck and back with Raj Rao, M.D., chair of the Department of Orthopaedic Surgery and professor of orthopaedic surgery and neurosurgery, and Anthony Caputy, M.D., FACS, chair of the Department of Neurological Surgery and the Rizzoli Professor of Neurological Surgery, as they continue our series on healthy aging.

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“HEALTHY TRAVELING: WHAT YOU NEED TO KNOW TO PREPARE FOR THIS VACATION SEASON” – WEDNESDAY, JUNE 1, 2016

Aileen Y. Chang, MD, MSPH, Assistant Professor of Medicine and Assistant Director of Research, GW Rodham Institute

David M. Parenti, MD, Professor of Medicine and Microbiology, Immunology, and Tropical Medicine and Director, Travelers’ Clinic at The GW Medical Faculty Associates

Moderator: Alan Wasserman, MD, FACC, MACP, Eugene Meyer Professor of Medicine, Chairman, Department of Medicine and Chairman, Council of Clinical Chairs

Summer is quickly approaching. As travelers prepare for the vacation season, concerns about the Zika virus and other health risks have many wondering if travel is safe this year. Join GW experts Aileen Y. Chang, MD, MSPH, assistant professor of medicine and assistant director for research at the GW Rodham Institute, and David M. Parenti, MD, professor of medicine and microbiology, immunology, and tropical medicine, and director of the Travelers’ Clinic at the GW Medical Faculty Associates, as they discuss what precautions you can take to protect yourself against the Zika virus, malaria, and other infectious diseases that travelers may encounter this summer.

FRONTIERS OF MEDICINE

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DEPARTMENT OF MEDICINE: GROSS CHARGES

FY GROSS CHARGES

FY09 $88,571,487

FY10 $91,639,232

FY11 $99,076,600

FY12 $106,413,170

FY13 $108,329,287

FY14 $112,921,447

FY15 $119,132,027

FY16 (Annualized based on May)

$126,347,697

$80,000,000.00

$85,000,000.00

$90,000,000.00

$95,000,000.00

$100,000,000.00

$105,000,000.00

$110,000,000.00

$115,000,000.00

$120,000,000.00

$125,000,000.00

$130,000,000.00

FY09 FY10 FY11 FY12 FY13 FY14 FY15 FY16(Annualized

basedonMay)

DepartmentofMedicine:GrossChargesDEPARTMENT OF MEDICINE: GROSS CHARGES

130,000,000

125,000,000

120,000,000

115,000,000

110,000,000

105,000,000

100,000,000

95,000,000

90,000,000

85,000,000

80,000,000

FY09 FY10 FY11 FY12 FY13 FY14 FY15 FY16(Annualized

based on May)

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RENAL GRANT NO PI DIRECT COSTS INDIRECT COSTS TOTAL

Renal dopamine-1 receptor defect in hypertension

R01 DK039308 Pedro Jose $257,949.00 $150,900.00 $408,849.00

Renal Dopamine Receptor & Regulation R37 HL023081 Pedro Jose $180,378.00 $105,521.00 $285,899.00

GRK4 & Development of Salt Sensitivity R01 HL092196 Pedro Jose $115,280.00 $67,438.00 $182,718.00

Renal vascular oxidative stress in hypertensionP01 HL068686 Sub from GT

Pedro Jose $320,000.00 $187,200.00 $507,200.00

Gut Microbiota and Atherosclerosis in ESRD NIDDK Dominic Raj $245,557.00 $139,443.00 $385,000.00

Anti-Inflammatory Therapy and Diabetic CKD NIDDK Dominic Raj $225,076.00 $131,669.00 $356,745.00

Sub with U of Washington PCORI Scott Cohen $3,825.00 $1,530.00 $5,355.00

SPRINT Dominic Raj $79,687.00 $11,953.00 $91,641.00

SUB-TOTAL $1,427,752.00 $795,654.00 $2,223,407.00

MEDICINE FEDERAL/FOUNDATION GRANTS FY 2016

CARDIOLOGY GRANT NO PI DIRECT COSTS INDIRECT COSTS TOTAL

Mobile Health PCORI Richard Katz $533,793.00 $109,904.00 $643,697.00

Lux Catheter STTR (sarvazyan) Marco Mercader $10,258.00 $6,000.00 $16,259.00

NIH (Effimov) Marco Mercader $17,925.00 $10,485.00 $28,410.00

Ramesh Mazhari

Joint Risk of Malpractice NIH Steven Farmer $433,298.00 $146,845.00 $580,193.00

Merkin Fellow Brookings/Duke Steven Farmer $146,712.00 $29,342.00 $176,054.00

AHRQ (Dor) Steven Farmer $6,353.00 $1,103.00 $7,456.00

Mobile system for Diet and coaching Vignet (SBIR) Brian Choi $51,461.00 $33,615.00 $91,076.00

911 campaign SPHHS Jannet Lewis $12,611.00 $4,654.00 $13,727.00

SUB-TOTAL $1,194,486.00 $341,948.00 $1,536,434.00

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RHEUMATOLOGY GRANT NO PI DIRECT COSTS INDIRECT COSTS TOTAL

Chronic Wounds NIH Vicki Shanmugam $259,174.00 $115,171.00 $374,375.00


INFECTIOUS DISEASES GRANT NO PI DIRECT COSTS INDIRECT COSTS TOTAL

Cocaine enhances -HIV NIH Mudit Tyagi $40,000.00 $23,400.00 $63,400.00

Cocaine induced pathways -HIV NIH Mudit Tyagi $50,000.00 $29,250.00 $79,250.00

DC-CFAR NIH Marc Siegel $48,567.00 $48,567.00

CTSA NIH/CNMC Gary Simon $56,490.00 $31,917.00 $88,406.00

DC-D-CFAR Gary Simon $10,714.00 $6,268.00 $16,982.00

Lipoprotein-HIV NIH(Bukrinsky) Gary Simon $31,126.00 $18,208.00 $49,335.00

HPTN-069, 073 NIH (SPHHS) Marc Siegel $54,564.00 $31,920.00 $86,429.00

HPTN 081/085 NIH (SPHHS) Marc Siegel $60,000.00 $35,700.00 $95,700.00

Sexual Violence NIH (SPHHS) Afsoon Roberts $16,317.00 $9,545.00 $25,862.00

Hookworm Vaccine Diemert Gary Simon $340,299.00 $40,835.00 $381,135.00

DC Cohort SPHHS David Parenti $100,860.00 $35,501.00 $136,161.00

SUB-TOTAL $810,937.00 $262,544.00 $1,073,481.00

ENDOCRINOLOGY GRANT NO PI DIRECT COSTS INDIRECT COSTS TOTAL

P53 and diabetes AHA Saby Sen $70,000.00 $7,000.00 $77,000.00

HEMATOLOGY/ONCOLOGY GRANT NO PI DIRECT COSTS INDIRECT COSTS TOTAL

Cross tolerance NCI Eduardo Sotomayor $98,714.00 $57,747.00 $156,461.00

SPORE NCI Eduardo Sotomayor $211,050.00 $123,464.00 $334,514.00

Dual PI NCI Eduardo Sotomayor $228,750.00 $133,818.00 $362,568.00

SUB-TOTAL $539,514.00 $315,029.00 $854,543.00

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INTERNAL MEDICINE GRANT NO PI DIRECT COSTS INDIRECT COSTS TOTAL

Parents-Children Weight Los Landenberg Ginger Winston $100,000.00 $- $100,000.00

Prevention at Home CMS El-Bayoumi $325,000.00 $190,125.00 $515,125.00

Low Intensity post meal walking NIH Brad Moore $21,042.00 $12,309.00 $33,351.00

SUB-TOTAL $446,042.00 $202,434.00 $648,476.00

INVESTIGATOR INITIATED PROJECTS

SPONSOR PI DIRECT COSTS INDIRECT COSTS TOTAL

BristolMyers Squibb Rudolfo Curiel $316,705.00 $95,611.00 $411,717.00

Boehringer Ingelheim Saby Sen $277,200.00 $83,160.00 $360,360.00

Astra Zeneca Saby Sen $253,777.00 $76,133.00 $329,910.00

Total $847,682.00 $254,904.00 $1,101,987.00


DEPARTMENT GRANT NO PI DIRECT COSTS INDIRECT COSTS TOTAL

Direct Cost Funding from Federal Grants (DOM PI's) $3,694,604.00 $2,039,549.43 $5,277,815.00

Direct Cost Funding from Federal Grants (DOM Co- PI's)

$1,053,301.00 $428.57 $1,482,871.00

TOTAL All Federal Funding $4,747,905.00 $2,039,978.00 $6,760,686.00

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RESEARCH EXPENDITURES BY DEPARTMENT

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BASIC SCIENCE DEPARTMENTS GW-MFA CLINICAL DEPARTMENTS ACADEMIC SUPPORT UNITS

RESEARCH EXPENDITURES BY DEPARTMENTExcludes Cost Share

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$8

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FACULTYLawrence DuBuske, MD, Clinical Professor of MedicineRichard Nicklas, MD, Clinical Professor of MedicineJanine Van Lancker, MD, Assistant Professor of Medicine

VA FACULTYRaghava Charya, MD, Assistant Professor of MedicineDipa Sheth, MD, Assistant Professor of Medicine

UPCOMING FACULTYAnjeni Keswani, MD, Assistant Professor of Medicine Jennifer Kannan, MD, Assistant Professor of Medicine

RESEARCH ACCOMPLISHMENTSThe following are some representative references of publications and presentations coming from our faculty.

Dr. Lawrence DuBuske, through his international collaborations, has presented numerous posters and abstracts at our two national meetings. These are attached.

Our biggest initiative is a national collaborative drug allergy study which I am organizing, involving eight leading academic allergy centers and the major commercial lab doing advanced immunology tests. We are applying for an NIH grant, which we are about to submit and which we have reason to believe has a high chance of acceptance. We see this as the beginning of a much larger and longer effort to organize an NIAID-sponsored drug allergy network of investigators.

ALLERGYDANIEL EIN, MDClinical Professor of Medicine, Division Director

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CLINICAL ACCOMPLISHMENTSThere are more medical students and residents than ever taking electives in our clinic and continue to send one or more residents to Allergy Fellowships every year. Allergy has continued a steady stream of consultations at GWUH, providing a valuable addition to the services available at the hospital. Also, Allergy is getting more referrals from outside MFA as they become recognized as one of very few centers for clinical excellence in Allergy in the DC area.

EDUCATION ACCOMPLISHMENTSAs noted above, we are training increasing numbers of medical students and residents in Allergy and that has fueled increased interest in a number of them choosing a career in Allergy.

We are also in the third year of a very successful collaboration with NIAID by which we are the major clinical venue for training their Allergy Fellows in clinical Allergy. Each of their four first year Fellows spends three months with us. The feedback we get is that they are very happy with the experience. In turn, we are very impressed with their performance.

PUBLICATIONSDr. Richard Nicklas• Fonacier L et al. Contact Dermatitis: a practice parameter update 2015. J

Allergy Clin Immunol; In practice. 2015; 3:1-39.• Lieberman P, Nicklas RA, Oppenheimer J et al. Updated parameter on

anaphylaxis. J Allergy Clin Immunol; In practice. Practice parameter update2015; Ann Allergy Asthma Immumnol 2015; 115:341.

• Bonilla, FA, Khan DA, Ballas ZK et al. Practice parameter for the diagnosis and management of primary immunodeficiency. J Allergy Clin Immunol 2015; 136; 1186-1205

ABSTRACTSDr. Lawrence DuBuske• 13 abstracts presented in March, 2016 at AAAAI Annual Meeting in Los

Angeles, California. All were published in “JACI”.• 20 abstracts presented in June, 2015 at EAACI Annual Meeting in Barcelona

Spain, all were published in “Allergy”.• 12 abstracts presented in November 2015 at ACAAI meeting in Houston. All

published in Annals of Allergy

PRESENTATIONS OF NOTE• INTERASMA 23rd World Congress of Asthma, Madrid, Spain, March 14, 2016:

ACAAI Symposium- “Toll Like Receptor Agonists as Adjuvants in Allergen Immunotherapy”

• INTERASMA 23rd World Congress of Asthma, Madrid, Spain, March 15, 2016: “Asthma Therapies as COPD Therapies: The Role of Cytokine Antagonists”

• EAACI Annual Meeting June 6 to 10, 2015, Barcelona, Spain: Moderator: “New Considerations in Allergic Disease”; Lecture: “Advances in the Pathophysiology of Atopic Dermatitis- Work of Andrei Kurchenko”

• ENT Grand Rounds- GWU- June 17, 2015: “Immunoadjuvants and Allergen Immunotherapy”

ALLERGY SPONSOR INCOME

Dr. Daniel Ein Circassia LTD $5,495.00

Total $5,495.00

INDUSTRY RESEARCH

ALLERGY

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CARDIOLOGYRICHARD KATZ, MDBloedorn Professor of Medicine, Division Director

CYNTHIA TRACY, MDProfessor of Medicine, Associate Director

FACULTYWilliam Borden, MD, Associate Professor of Medicine; Director of Healthcare Delivery TransformationAndrew Choi, MD, Assistant Professor of Medicine and Radiology; Co-Director, Cardiac CT and MRIBrian Choi, MD, Associate Professor of Medicine and Radiology; Co-Director, Advanced Cardiac ImagingSteven Farmer, MD, Associate Professor of MedicineJannet Lewis, MD, PhD Professor of Medicine; Director, Non-Invasive Cardiology; Director, GW Women’s Heart CenterLisa Martin, MD, Associate Professor of Medicine; Director, Lipid ClinicRamesh Mazhari, MD, Associate Professor of MedicineMarco Mercader, MD, Associate Professor of MedicineChristian Nagy, MD, Assistant Professor of MedicineGurusher Panjrath, MD, Assistant Professor of Medicine; Director, Heart Failure and Mechanical Circulatory Support Program

Jonathan Reiner, MD, Professor of Medicine; Director, Cardiac Catheterization LaboratoriesScott Shapiro, MD, Assistant Professor of Medicine; Director, Arrhythmia ServicesAllen Solomon, MD, Professor of Medicine; Director, Cardiology Fellowship; Director, CCUAlan Wasserman, MD, Eugene Meyer Professor of MedicineWilliam Weglicki, MD, Professor of Medicine; Professor of Biochemistry and Molecular Biology

PAs/NPs

Karen Barr, NPLinda Bostrom, NPMonique Nylund-Alm, NPHelma Parikh, NPKelli Metzger, RD

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CARDIOLOGYRESEARCHThe Cardiology Division has had a productive year in the area of research. We have several ongoing and new grants. Dr. Katz is completing year 3 of his PCORI grant and Dr. Farmer continues his RO1 as well as his work on health policy at Duke University. New funding includes an NIH SBIR (Mercader), NIH SBIR subcontract (Choi/Katz), and Aetna Foundation grant (Panjrath/Katz). In addition, our Heart and Vascular Institute provided over $50,000 funds for internal investigator-initiated research focusing on fellow and new faculty projects. The cardiology faculty has published and presented over 30 manuscripts and abstracts. Research areas span heart failure, cardiac imaging, cardiac arrhythmias, women’s heart health, coronary artery disease, population health and health policy. These projects included co-authorship with GW residents, fellows and students. Presentations were at major national meetings including the American Heart Association, American College of Cardiology, Heart Rhythm Society, SCAI, American Society of Echocardiography and the European Valve Summit. CLINICALClinical accomplishments have extended our high quality cardiac care. The TAVR program has grown dramatically with over 60 cases completed this year. Our new faculty member, Andrew Choi, has been an excellent addition to our division working closely with Radiology to increase advanced cardiac imaging with MRI and CT. Our STEMI door-to-balloon time has been outstanding with >90% patients treated in less than 90 minutes. Our innovative heart failure 30 day readmission program using community health workers has exceeded all expectations. This past year 30 day readmissions fell from over 20% to 11%. This data was presented at the American College of Cardiology in March 2016 and is the basis for a new NHLBI research grant submission in fall 2016.

EDUCATIONALEducational programs in the Cardiology Division remain robust with 11 current cardiology fellows. These training programs are under the leadership of Al Solomon (general cardiology fellowship), Ramesh Mazhari (interventional cardiology fellowship), and Cynthia Tracy (electrophysiology fellowship). We continue our weekly catheterization, noninvasive, EKG, and heart failure conferences and added a biostatistician, Heather Young, to our biweekly journal club. The GW Heart and Vascular Institute sponsored 3 visiting professors for our Cardiology and Medical Grand Rounds. Fellows have had new opportunities with electives in vascular ultrasound and pulmonary hypertension.

We have strengthened our relationship with the Inova Cardiology program with plans to consider expanding our fellowship. For medical students, Dr Panjrath updated and organized a highly successful Cardiovascular 1st year course. Dr. Mercader expanded his highly popular EKG elective to 80 students and supervised our Cardiology elective for nearly 30 students. Drs. Mercader and Panjrath organized our 2nd annual Heart Failure/Cardiac Arrhythmia CME symposium featuring the GW faculty.

Service has been another mission for our Cardiology Division. We conducted our 6th annual Honduras mission, volunteered at Food and Friends, provided our nutritionist for free to DC community clinics, and pushed forward with a bill to promote AEDs. Each month we send an electronic newsletter to over 12,000 patients highlighting our recent accomplishments. We also produced our 2015 Heart and Vascular Institute Annual Report and raised over $500,000 for new programs.

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GW HEART AND VASCULAR INSTITUTE FACULTY RESEARCH FY 2015

Young Investigator Pilot Research Funded by the Institute $62,500

Research Funded by Federal/Foundation/Industry Grants: Federal Grants $2,929,976Foundation Grants $2,280,761Medical Industry Grants $36,906

Total Research Grant Support $5,310,143

INTERNATIONAL WORKHonduras - Dr. Cynthia Tracy (Cardiology) and colleagues travel every summer to Honduras. During the two week mission, the GW team evaluates heart failure and arrhythmia patients, implanting free pacemakers and defibrillators in at risk patients. Since 2010, Dr. Tracy has acquired more than $2.5 million in donated heart devices.

AWARDSDr. Andrew Choi, Cardiology, received the Young Investigator Award at the Society of Cardiovascular CT annual meeting in Las Vegas, NV on his paper, “Coronary Artery Calcium Scoring on 320 Detector Row CT Demonstrates Low Interscan Variability at Standard and 70% Reduced Radiation Dose.”

Dr. Cynthia Tracy participated in writing the 2015 ACC/AHA/HRS Guideline for the Management of Adult Patients with Supraventricular Tachycardio.

Drs. Ju Kim and Gurpreet Sodhi, Cardiology Fellows, were awarded the 2015-2016 GW Heart & Vascular Institute’s Young Investigator Pilot Research Award.

Dr. Gurusher Panjrath, Cardiology, was invited to serve as a member of the Academic Cardiology Section Leadership Council for the American College of Cardiology.

Dr. Marco Mercader, Cardiology, was honored by the University of Puerto Rico. The Association of University of Puerto Rico Alumni and Friends Abroad (UPRAA) presented Dr. Mercader the UPRAA’s Excellence and Achievement Award for outstanding accomplishments in Medicine.

CARDIOLOGY

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CARDIOLOGYPUBLICATIONS• Choi BG, Akinniyi DC, Young HA, Alzenaidi A, Twum-Ampofo JK, Lewis JF.

Assessment of appropriate use criteria for stress echocardiography in the emergency room evaluation of chest pain. Experimental & Clinical Cardiology. 2014; 20(8): 4507-24.

• Vedanthan R, Choi BG, Baber U, Narula J, Fuster V. Bio-imaging and subclinical cardiovascular disease in low-and middle-income countries. The Journal of Cardiovascular Translational Research. 2014; 7(8):701-10.

• Mollura DJ, Shah N, Mazal J, Choi BG (RAD-AID Conference Writing Group). White paper report of the 2013 RAD-AID conference on international radiology for developing countries: access to radiology services in limited resource regions. Journal of the American College of Radiology. 2014; 11(9):913-9.

• Vehian AV, Choi BG, Rekhi SS, Young HA, Dusaj RS, Zeman RK. Clinical significance of left atrial anatomic abnormalities identified by CT. Advances in Computed Tomography. 2015; 4(1): 1-8.

• Dusaj RS, Mukherjee M, Furmark L, Katz RJ, Choi BG, Lewis JF. Pulmonary hypertension complicating systemic hypertension: is diastolic dysfunction the culprit? Journal of Cardiology & Clinical Research. 2014; 2(1): 1015.

• Choi BG, Yang BK, Sanai R, Dusaj RS, Mazhari R, Reiner JS, Young HA, Lewis JF. Contrast echocardiography transit time for estimation of pulmonary vascular resistance and cardiac index: a prospective pilot study. Cardiovascular Ultrasound. 2014; 12(1):44.

• Fishman ML, Shea J, Choi BG, Solomon AJ. Feasibility of focused cardiac ultrasound in pre-participation screening. Int J Sports Exerc Med. 2015; 1:011.

• Fan P, Mukherjee M, Mehta NK, Connolly JJ, Dusaj RS, Choi BG, Katz RJ, Lewis JF. Continuing medical education activity in echocardiography. Echocardiography. 2014; 31(4):441.• Dilsizian V, Arrighi JA, Cohen RS, Miller TD, Solomon AJ, Udelson JE.

COCATS 4 Task Force 6: Training in Nuclear Cardiology. J Am Coll Cardiol. 2015; 5;65(17):1800-9.

• Dilsizian V, Arrighi JA, Cohen RS, Miller TD, Solomon AJ, Udelson JE. COCATS 4 Task Force 6: Training in Nuclear Cardiology: Endorsed by the American Society of Nuclear Cardiology. J Nucl Cardiol. 2015; 4:812-25.

• Pines JM, Farmer SA, et al. The Maryland Medicare waiver and emergency care: mixed experiences deserve close scrutiny. Am J Med Qual. 2015; 30(2): 186-187.

• Borden WB, Maddox TM, Tang F, Rumsfeld JS, Oetgen WJ, Mullen JB, Spinler SA, Peterson ED, Masoudi FA, Impact of the 2014 Expert Panel Recommendations for Management of High Blood Pressure on Contemporary Cardiovascular Practice: Insights from the NCDR PINNACLE Registry. Journal of the American College of Cardiology. 2014; 64(21):2196-2203.

• Wasfy JH, Borden WB, Secemsky EA, McCabe JM, Yeh RW. Public Reporting in Cardiovascular Medicine: Accountability, Unintended Consequences, and Promise for Improvement. Circulation. 2015; 131: 1518-1527.

• Borden WB, Mushlin AI, Gordon JE, Leiman JM, Pardes H. A New Conceptual Framework for Academic Health Centers. Academic Medicine. 2015 May; 90(5):569-73.

• Farmer SA and Borden WB. Setting the stage for evidence-based medicine. Circ Cardiovasc Qual Outcomes. 2015; 8(3): 223-225.

• Borden WB, Chiang YP, Kronick R. Bringing Patient-Centered Outcomes Research to Life. Value in Health. 2015 Jun; 18(4):355-7.

• Schmiegelow MD, Hedlin H, Stefanick ML, Mackey RH, Allison M, Martin LW et al. Insulin Resistance and Risk of Cardiovascular Disease in Postmenopausal Women. Circulation Outcomes. 2015; 114.001563.

• Saleb K, GibrealM, Sodhi G, Solomon A. Spontaneous coronary artery dissection: a rare diagnosis in a postmenopausal woman. Oxf Med Case Reports. 2015; 1:173-76.

• Schmiegelow, MD, Hedlin H, Stefanick ML, Mackey RH, Allison M, Martin LW, et al. Insulin Resistance and Risk of Cardiovascular Disease in Postmenopausal Women A Cohort Study From the Women’s Health Initiative. Circulation Outcomes. May 5, 2015.

• Greenberg JA, Manson JE, Buijsse B, Wang L, Allison MA, Neuhouser ML, Tinker L, Waring ME, Isasi CR, Martin LW, Thompson CA. Chocolate-Candy Consumption and 3-Year Weight Gain Among Postmenopausal U.S. Women. Obesity. 2015; 23, 677-683.

• Salmoirago-Blotcher E, Hovey KM, Andrews CA, Robinson JG , Johnson KC, Wassertheil-Smoller S, Crawford S, Qi L, Martin LW, et al. Statin use and risk of haemorrhagic stroke in a community-based cohort of postmenopausal women: an observational study from the Women’s Health Initiative. BMJ. Feb 2015; Open2015;5:e007075/bmjopen-2014-007075.

• Donneyong MM, Hornung CA, Taylor KC, Baumgartner RN, Myers JA, Eaton CB, Gorodeski EZ, Klein L, Martin LW, et al. Risk of Heart Failure Among Postmenopausal Women A Secondary Analysis of the Randomized Trial of Vitamin D Plus Calcium of the Women’s Health Initiative. Circulation: Heart Failure. 2015; 8: 49-56.

• Tabung FK; Zhang J; Ma Y; Liese AD; Agalliu I; Hingle M; Hou L; Hurley TG; Jiao L; Martin LW, et al. Construct Validation of the Dietary Inflammatory Index among Postmenopausal Women. Annals of Epidemiology. March 12, 2015.

• Paynter NP, LaMonte MJ, Manson JE, Martin LW, et al. Comparison of lifestyle-based and traditional cardiovascular disease prediction in a multiethnic cohort of nonsmoking women. Circulation. 2014 Oct 21; 130(17):1466-73.

• Agha G, Loucks EB, Tinker LF, Waring ME, Michaud DS, Foraker RE, Li W, Martin LW, et al. Healthy lifestyle and decreasing risk of heart failure in women: the Women’s Health Initiative observational study. J Am Coll Cardiol. 2014 Oct 28; 64(17):1777-85.

• Paynter NP, LaMonte MJ, Manson JE, Martin LW, et al. Comparison of lifestyle-based and traditional cardiovascular disease prediction in a multiethnic cohort of nonsmoking women. Circulation. 2014 Oct 21; 130(17):1466-73.

• Zaslavsky O, Cochrane B, Woods NF, LaCroix A, Liu J, Herting J, Goveas JS, Johnson KC, Kuller LK, Martin LW, et al. Trajectories of Positive Aging: Observations from the Women’s Health Initiative Stud. International Psychogeriatrics Association. 2014; Doi: 10. 1017.

• Schnatz, PF, Martin LW, et al. Calcium/Vitamin D (CaD) Supplementation, Serum 25(OH) Vitamin D Concentrations, and Cholesterol Profiles in the Women’s Health Initiative CaD Randomized Trial. Menopause. 2014; 21 (8):823-833.

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• Azarbal F, Stefanick ML, Salmoirago-Blotcher E, Manson JE, Albert CM, LaMonte MJ, Larson JC, Li W, Martin LW, et al. Obesity, physical activity, and their interaction in incident atrial fibrillation in postmenopausal Women. J Am Heart Assoc. 2014 Aug 20; 3(4).

• Shimbo D, Martin LW, et al. The effect of hormone therapy on mean blood pressure and visit-to-visit blood pressure variability in postmenopausal women: results from the Women’s Health Initiative randomized controlled trials. Journal of Hypertension. 2014 July; 32(10).

• Maddox T, Tang F, Virani SS, Oetgen WB, Mullen B, Chan P, Casale P, Douglas PS, Masoudi FA, Farmer SA, et al. Implications of the 2013 ACC/AHA Cholesterol Guidelines for Adults in Contemporary Cardiovascular Practice: Insights From the NCDR PINNACLE Registry. J Am Coll Cardiol. 2014; 64(21): 2183-2192.

• Maddox TM, Borden WB, Tang F, Virani SS, Oetgen WJ, Mullen JB, Chan PS, Casale PN, Douglas PS, Masoudi FA, Farmer SA, Rumsfeld JS. Implications of the 2013 ACC/AHA Cholesterol Guidelines for Adults in Contemporary Cardiovascular Practice: Insights from the NCDR PINNACLE Registry. Journal of the American College of Cardiology. 2014; 64(21):2183-2192.

• Borden WB, Marier AF, Dennison TH, Freund DA, Cook K, Mushlin AI. Assessing Variation in Utilization for Acute Myocardial Infarction in New York State. Healthcare. 2014 Sep; 2(3):196-200.

• Farmer SA, et al. Hospital-level variation in use of cardiovascular testing for adults with incident heart failure: findings from the cardiovascular research network heart failure study. JACC Cardiovasc Imaging. 2014; 7(7): 690-700.

• Mazhari R, Toma IV. Immunogenic aspects of stem cell therapy in regenerative medicine. MJHS. 2014 Jan; 23.

• Dusaj RS, Mukherjee M, Furmark L, Katz RJ, Choi BG, Lewis JF. Pulmonary Hypertension Complicating Systemic Hypertension, Is Diastolic Dysfunction the Culprit? J Cardiol Clin Res. 2014; 2:1015-8.

• Shapiro SD, Amresh K Ranjan AK, et al. Cyclin A2 induces cardiac regeneration after myocardial infarction through cytokinesis of adult cardiomyocytes. Science Translational Medicine. 19 Feb 2014; Vol. 6, Issue 224, pp. 224ra27.

• Mukherjee M, Mehta NK, Connolly JJ, Dusaj RS, Choi BG, Katz RJ, Lewis JF. Pulmonary hypertension in hypertensive patients: association with diastolic dysfunction and increased pulmonary vascular resistance. Echocardiography. 2014; 31(4):442-8.

• Tangherlini F, Choi BG, Solomon AJ. 63-year-old woman presents with palpitations. Heart. 2014; 101(3):184,229.

• Sodhi G, Shea J, Najam F, Solomon AJ. Can a genetic test predict the development of postoperative atrial fibrillation? Int J Clin Cardiology. 2015; 2:3.

• Shea J, Sodhi G, Najam F, Solomon AJ. Does the addition of atrial pacing to amiodarone reduce the incidence of postoperative atrial fibrillation: a pilot study? Journal of Thoracic and Cardiovascular Surgery. 2014; 148, 4, 1752-1753.

• January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014 Dec 2; 130(23):2071-104.

• Tracy C. Pacemaker after transcatheter aortic valve replacement: unexpected, but not infrequent outcome. J Am Coll Cardiol. 2014; 64(2):141-143.

• Tracy C, Boushahri A. Managing arrhythmias in the intensive care unit. Crit Care Clin. 2014 Jul; 30(3):365-90.

• January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014 Dec 2; 64(21):e1-76. Erratum in: J Am Coll Cardiol. 2014 Dec 2; 64(21):2305-7.

• Levine GN, Tracy CM, et al. 2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. J Am Coll Cardiol. 2015 Oct 21.

• Page RL, Joglar JA, Caldwell MA, Calkins H, Conti JB, Deal BJ, Estes NA 3rd, Field ME, Goldberger ZD, Hammill SC, Indik JH, Lindsay BD, Olshansky B, Russo AM, Shen WK, Tracy CM, Al-Khatib SM. 2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2015 Sep 16.

• Zipes DP, Tracy CM, et al. 2015 ACC/AHA/HRS Advanced Training Statement on Clinical Cardiac Electrophysiology (A Revision of the ACC/AHA 2006 Update of the Clinical Competence Statement on Invasive Electrophysiology Studies, Catheter Ablation, and Cardioversion). J Am Coll Cardiol. 2015 Sep 14.

• Guzman-Martinez, G., Fernandez-Friera, L., Moral, S., Shapiro, S., Bates, D. et al. Intra-scar perfusion heterogeneity by cardiac magnetic resonance in a porcine model of non-reperfused myocardial infarction. International Journal of Cardiology. 2014; 176(3), 1288-1289.

• Mazhari R, Kapur N. Increased risk and increased reward in coronary intervention in older patients with acute coronary syndrome. Heart. 2014 Jun 19.

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ABSTRACTS• Imaging: Assessment in Stable Outpatient Hypertensive Patients. J Am Soc Echo.

2014.• Emerson DA, Amdur RL, Morrissette JR, Mordini FE, Nagy CD, Greenberg MD,

Trachiotis GD. Using cardiac magnetic resonance imaging to evaluate cardiac function and predict outcomes in patients with valvular heart disease. Innovations (Phila). 2015; Jan-Feb;10(1):63-7.

• Alhamoud HA, Dudum R, Young H, Choi BG. Discrepancies between author self-disclosure and pharmaceutical company reporting of payments to physicians: an analysis of American College of Cardiology and American Heart Association guideline authors. Journal of the American College of Cardiology. 2015; 65(10): A336.

• Alhamoud HA, Dudum R, Young HA, Choi BG. Author self-disclosure compared to pharmaceutical company reporting of physician payments. American Journal of Medicine. 2015; pii:2015.06.028.

• Borden WB, Maddox TM, Tang F, Ryan A, Rumsfeld JS, Oetgen WJ, Joynt KE, Deano RC, Farmer S, et al. Assessing the Validity of Physician Quality Reporting. American College of Cardiology Scientific Sessions. 2015; San Diego, CA.

• Borden WB, Lin H, Bishop TF, Mushlin AI, Simon KI. Impact of Medical Study Publication on Cholesterol Medication Prescriptions. American Heart Association Scientific Sessions. 2014.

• Maddox TM, Borden WB, Tang F, Virani SS, Oetgen WJ, Mullen JB, Chan PS, Casale PN, Douglas PS, Masoudi FA, Farmer SA, Rumsfeld JS. Implications of the 2013 ACC/AHA Cholesterol Guidelines for Adults in Contemporary Cardiovascular Practice: Insights from the NCDR PINNACLE Registry. American Heart Association Scientific Sessions. 2014.

• Borden WB, Maddox TM, Tang F, Rumsfeld JS, Oetgen WJ, Mullen JB, Spinler SA, Peterson ED, Masoudi FA. Impact of the 2014 Expert Panel Recommendations for Management of High Blood Pressure on Contemporary Cardiovascular Practice: Insights from the NCDR PINNACLE Registry. American Heart Association Scientific Sessions. 2014.

• Panjrath GS, Schwarzberg R, Garson A, Katz R. Maximizing the potential of mHealth Heart Failure management: Integrating mHealth with Grand Aides®. Wireless Health 2014. Oct 2014; NIH, Bethesda, MD.

• Mazhari R, Konjedi N, Moussavi F, Murphy C, Sadri M, Panjrath G, Shah P, Kim J. Application Of Genomic Markers To Predict Outcome In Patients Receiving Left Ventricular Assist Device (LVAD) Therapy. Circulation. 2014; 130: A16341.

• Murphy C, Sadri M, Panjrath G, Shah P, Desai S, Burton NA, Toma I, McCaffrey T. Application Of Genomic Markers To Predict Outcome In Patients Receiving Left Ventricular Assist Device (LVAD) Therapy. American Heart Association Scientific Sessions. November 2014; Chicago, IL.

• Mercader M, Moak J, He D, Emerson D, Trachiotis G, Blicharz A, Montague E, Li X, Borzin G, Berul C, Jonas R. Selective Cardiac Neurostimulation for Rate Control of Post-Operative Atrial Arrhythmias. Heart Rhythm Society. May 2015; Boston, MA.

• Armstrong KC, Ransbury T, Reddy V, Koruth J, Amirana O, Sarvazyan N, Larson C, Bowen J, Mercader M. Optical Tissue Interrogation for Real-Time Monitoring of Catheter-Tissue Contact and RF lesion Progression. Heart Rhythm Society. May 2015; Boston, MA.

• Armstrong KC, Ransbury T, Reddy V, Koruth J, Amirana O, Sarvazyan N, Larson C, Bowen J, Mercader M. Real-Time Dual Monitoring of Catheter-Tissue Contact and RF Lesion Progression Using NADH Fluorescence. 20th Annual International Atrial Fibrillation Symposium. Jan 2015; Orlando, FL.

• Tracy CM. Debate entitled Only Patients with Left Bundle Branch Block Should Receive CRT- Antagonist. Heart Rhythm Society. May 2015; Boston, MA.

• Sadri M, Nagy C, Chawla M, Reiner J, Mazhari R. Avoiding the Low road. Cath access site and acute kidney injury. SCAI. 2015; San Diego, CA.

• Maziar S, Chawla M, Nagy C, Reiner JS, Mazhari R. Risk of CIN in patients with ACS undergoing trans-femoral vs trans-radial coronary angiography and intervention. SCAI. 2015; San Diego, CA.

• Katz R, Nunlee-Bland G, Magee M, Cioletti A, Cohen J, Getaneh A, Larbi D, Witkin L, Nassar C, Payne D. Making mHealth work to manage diabetes: Integrating mHealth with Community Health Workers. 75th Scientific Sessions of the American Diabetes Association. 2015; Boston, MA.

• Katz R, Patel S, Cohen J, Young H. Diabetes and Hypertension Self-Management: A Randomized Trial of a mHealth Strategy in a Community Setting. 75th Scientific Sessions of the American Diabetes Association. 2015; Boston, MA

• Cohen J, Johnson J, Katz R. Engagement with a Mobile Health Diabetes Self-Management Program. 75th Scientific Sessions of the American Diabetes Association. 2015; Boston, MA.

• Panjrath G, Schwarzberg R, Garson A, Katz R. Maximizing the Potential of mHealth Heart Failure Management: Integrating mHealth with Grand Aides®. Wireless Health 2014. Oct 2014; NIH, Bethesda, MD.

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CARDIOLOGYINDUSTRY RESEARCH

CARDIOLOGY SPONSOR INCOME

Lisa Martin, M.D. NOVARTIS PHARMACEUTICALS CORP $1,935.90

Lisa Martin, M.D. PHARMANET, LLC $2,661.00

Lisa Martin, M.D. MEDPACE INC. $3,145.00

Allen Solomon, M.D. COVANCE INC. $1,760.74

Cynthia Tracy, M.D. BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. $4,720.00

Panjrath Gursher ALNYLAM PHARMACEUTICALS $16,211.90

Department Total $30,434.54

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ENDOCRINOLOGYJOSHUA COHEN, MDProfessor of Medicine; Interim Division Director

FACULTYSuzanne Adler, MD, Associate Clinical Professor of MedicineNicole Ehrhardt, MD, Assistant Professor of MedicineMichael Irwig, MD, Associate Professor of Medicine; Director, AndrologyNisha Nathan, MD, Assistant Professor of MedicineJill Paulson, MD, Assistant Professor of MedicineSabyasachi Sen, MD, MRCP, Associate Professor of Medicine; Associate Professor, Anatomy and Regenerative Medicine

VA FACULTYShikha Khosla, MD, Assistant Professor of MedicineEric Nylen, MD, Professor of MedicineShruti Gandhi, Assistant Professor of Medicine

NP/EDUCATORSu Chin, NPDiana Daniel, CDE

RESEARCHThe Endocrine Division faculty and fellows have continued their research programs with focuses on: diabetes and obesity, vascular biology, stem cells, mobile health, male hypogonadism and transgender care. This year, all of the endocrine fellows had abstracts presented at the Endocrine Society Annual Meeting. Division faculty also presented research findings at the American Diabetes Association Annual Meeting and at the 2015 International Thyroid Congress.Dr. Nicole Ehrhardt, Assistant Professor of Medicine, has continued her research on family-centered approaches for treatment of obesity. Dr. Ehrhardt this year was awarded a Redstone grant by the GWU School of Public Health as Co-Principal Investigator for the study “Effect of a communication-bolstered diabetes prevention program lifestyle intervention in young obese African-American maternal caregivers and their children.”

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Dr. Sen has continued his research program in vascular biology and endothelial and mesenchymal stem cells. During this past year he was the recipient of a new investigator-initiated grant award from Janssen Pharmaceuticals: “Role of canagliflozin on gene expression and function of CD34+ endothelial progenitor cells in patients with type 2 diabetes and mild chronic kidney disease.” In addition to studies conducted in his own laboratory and in collaboration with researchers in the Department of Pharmacology and Physiology, Dr. Sen also has active collaborations with researchers at the NIH and at the Washington DC Veterans Affairs Medical Center. Dr. Sen was the recipient of a patent “P53-silenced endothelial progenitor cells for diabetes” and has a patent pending for “Genetic modification of human mesenchymal stem cells helps to reduce adiposity and improve glucose tolerance in an obese diabetic mouse model.”

Dr. Joshua L. Cohen, Professor of Medicine, has continued his research studies involving novel applications of advanced technology to diabetes care. He is currently collaborating with Dr. Richard Katz (Division of Cardiology) on a multicenter trial “Changing the healthcare delivery model: a community health worker/mobile chronic care team strategy” funded by the Patient Centered Outcomes Research Institute (PCORI) to evaluate the impact on diabetes outcomes measures of deploying a combination of mobile health systems and community health workers in communities in Washington DC.

Dr. Irwig has continued his research on male hypogonadism. This year he published a study on depression and depressive symptoms in men referred for

evaluation of borderline testosterone levels. Dr. Irwig also published an authoritative review article on testosterone therapy for transgender men.

EDUCATIONEndocrine Division faculty members have had an active role in many components of undergraduate medical education at GW. Division faculty serve as instructors in the Clinical Skills and Reasoning course and the Professional Development program. They also mentor CAP students. This year the Endocrinology and Reproductive Medicine module for second year medical students was completely revised and introduced to very strong positive feedback from the medical students. This curriculum module incorporates real-time student responses, patient panels, hands-on workshops and team learning exercises to encourage active student involvement throughout. Medical students also rotate on the Endocrine Service both during their primary care rotation and as a clinical elective. In addition to GW students, the Clinical Endocrinology elective also attracted visiting students from other U.S. medical schools as well as international students from India, Japan, Palestine, Saudi Arabia and Spain.Endocrine faculty are also active in Graduate and Post-Graduate Medical Education. The Division has 5 endocrinology fellows in their 2 year training program. This year, the Endocrine Division was presented with the 2015 Residents Rocked the Boards Award, recognizing the division in the subspecialty in which the GW medicine residents performed the best on the ABIM board certification exam.

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CLINICAL ACTIVITIESThe division now has clinics at three locations: the MFA Pennsylvania Avenue and M Street sites and in Rockville, Maryland. Patient volume is increasing, there has been a 4.2% increase in patients arriving for appointments and 11.4% increase in new patient appointments compared to the previous year; net collections have increased by 16.1%.

This year the Endocrine Division welcomed Diana Daniel RN, CDE and Su Chin RN, NP, CDE to our clinical staff; they will focus on expanding comprehensive care for patients with diabetes, including diabetes and nutritional education, diabetes care in pregnancy, insulin pump therapy and continuous glucose monitor utilization. Also, analysis of thyroid fine needle aspiration samples has expanded to include next-generation gene sequencing and/or gene expression analysis where clinically appropriate.

Division faculty have participated also in community outreach programs. For example, Dr. Ehrhardt organized free HbA1C screening and nutrition and exercise counseling at the Barry Farm Community health Fair. Dr. Ehrhardt is also a volunteer physician at the Arlington Free Clinic.

AWARDSDr. Michael S. Irwig, Endocrinology, who was elected President of the Mid-Atlantic Chapter of the American Association of Clinical Endocrinologists (AACE).Dr. Sabyasachi Sen, Endocrinology, application was approval for Fellowship in the Royal College of Physicians (Edinburgh).

PUBLICATIONS• Sabyasachi Sen, Sarah Witkowski, Ann Lagoy, Ashequl M. Islam: A six-week

home exercise program improves endothelial function and CD34+ circulating progenitor cells in patients with pre-diabetes. J Endocrinol Metab.2015; 5 (1-2):163-171, doi: http://dx.doi.org/10.14740/jem273w

• Sabyasachi Sen, Cleyton Dominguez, Carol Rouphael, Cyril Chou, Chul Kim, Nagendra Yadava: Genetic modification of human mesenchymal stem cells helps to reduce adiposity and improve glucose tolerance in an obese diabetic mouse model: Stem Cell Research & Therapy.2015, 6:242. DOI: 10.1186/s13287-015-0224-9. URL: http://stemcellres.com/content/6/1/242.

• Xin Zhou, Darshan Patel, Sabyasachi Sen., Victoria Shanmugam, Anton Sidawy, Lopa Mishra, Bao-Ngoc Nyugen. Poly-ADP-ribose polymerase inhibition enhances ischemic and diabetic wound healing by promoting angiogenesis. Article in Press. Journal of Vascular Surgery, June 2016. DOI: http://dx.doi.org/10.1016/j.jvs.2016.03.407

• Ishita Prakash, Eric Sixtus Nylen, and Sabyasachi Sen, “Lithium as an Alternative Option in Graves Thyrotoxicosis,” Case Reports in Endocrinology, vol. 2015, Article ID 869343, 4 pages, 2015.

• Resmi Premji, Nira Roopnarinesingh, Joshua Cohen, Sabyasachi Sen: An Unusual Cause of Central Diabetes Insipidus: Case Reports in Endocrinology. Volume 2016 (2016), Article ID 2047410, 4 pages. http://dx.doi.org/10.1155/2016/2047410

• Phillips LA, Cohen J, Burns E, et al., Self-management of chronic illness: the role of ‘habit’ versus reflective factors in exercise and medication adherence., J Behav Med, 2016

• Irwig MS, Testosterone therapy for transgender men., The lancet. Diabetes & endocrinology, 2016 Apr, S2213-8587(16)00036-X [pii], 10.1016/S2213-8587(16)00036-X [doi]

• Irwig MS, TRANSGENDER CARE BY ENDOCRINOLOGISTS IN THE UNITED STATES., Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2016 Feb, 10.4158/EP151185.OR [doi]

• Westley CJ, Amdur RL, Irwig MS, High Rates of Depression and Depressive Symptoms among Men Referred for Borderline Testosterone Levels., The journal of sexual medicine, 2015 Aug, 12, 1753-60, 10.1111/jsm.12937 [doi], S1743-6095(15)34188-6 [pii]

• Irwig MS, Safety concerns regarding 5alpha reductase inhibitors for the treatment of androgenetic alopecia., Current opinion in endocrinology, diabetes, and obesity, 2015 Jun, 22, 248-53, 10.1097/MED.0000000000000158 [doi]

• Premji R, Joshi AS, Paulson JM, A Tale of Two Tumors and a Misleading FNA, Endocrine Society, 2016 Apr

• Kim J, Ramadoss P, Hine C, Bauerle K, Paulson JM, Miyazaki W, Asara J, Hao C, Souza Matos M, Mitchell J, Hollenberg A., Thyroid Hormone Signaling Regulates Endogenous Hydrogen Sulfide Production, International Thyroid Congress, 2015 Oct

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BOOK CHAPTER• Paulson JM and Hollenberg AN., Thyroid Emergencies, Principles and Practice of Hospital Medicine, McKean S, Ross J, Dressler D, Brotman D, Ginsberg J, McGraw-Hill

Medical, Burr Ridge, IL, 2015, 2nd edition not yet published, submitted.

INDUSTRY RESEARCH

ENDOCRINOLOGY

ENDOCRINE SPONSOR INCOME

Joshua Cohen, M.D. DCRI FINANCE $300.00

Sabyasachi Sen, M.D. ASTRAZENECA $149,255.00


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GASTROENTEROLOGYMARIE BORUM, MD, EdD, MPHProfessor of Medicine, Division Director

FACULTYM. Aamir Ali, MD, Associate Professor of MedicineShowkat Bashir, MD, Assistant Professor of Medicine- Promoted 7/1/2016 to Associate Professor of MedicineMatthew Chandler, MD, Assistant Professor of MedicineTimothy Dougherty, MD, Assistant Professor of MedicineSands Irani, MD, Clinical Associate Professor of Medicine- Promoted 7/1/2016 to Clinical Professor of Medicine Anita Kumar, MD, Assistant Professor of MedicinePatricia Latham, MD, Professor of Pathology and Medicine; Chief, Autopsy Service Internist (Hepatology)Lakshmi Lattimer, MD, Assistant Professor of MedicineAntoinette Saddler, MD, Assistant Professor of MedicineSteven Zeddun, MD, Assistant Professor of Medicine

VA FACULTYMichael Yao, MD, Associate Professor of MedicineNazia Qazi, MD, Assistant Professor of Medicine

CLINICAL ACTIVITIESThe Division of Gastroenterology and Liver Diseases increased patient encounters for office visits and endoscopic procedures by optimizing appointment access. This was accomplished through physician engagement and improved efficiency. A divisional model was developed and implemented. Individual and aggregate clinical activity was monitored. A trajectory was assessed and projections were exceeded.

Clinical ProductivityThere was an increase of 39% in office visits and 25% in procedure volume achieved through a process of template standardization, optimization of endoscopy capacity utilization and monthly monitoring of individual productivity. Increased clinical activity occurred through physician collaboration during weekly meetings that allowed for physician engagement and reinforcement of goals. Meetings incorporated nonjudgmental discussions and information sharing which allowed for identification of opportunities and challenges. There was frequent and specific guidance offered to those not meeting productivity expectations. Goal setting occurred without administrative or financial incentives.

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Office visitsOffice activity increased by 39%, with monthly increase in activity noted in figure 1. Divisional template for office visits was developed recognizing external and internal factors impacting MFA health care delivery. Expectations were established and accepted. Office staff were informed of divisional goals and supported activity. Physician activity was monitored, with adjustment of office capacity and voluntary opening of clinic appointments during administrative time to meet physician and divisional monthly goals. Specific guidance offered to those to enhance and sustain productivity.

EndoscopyProcedure activity increased by 25%, with monthly increase noted in figure 1. Divisional template was established for utilization of procedure time, based upon individual office activity. Collaborated with hospital to develop and implement processes to optimize utilization of endoscopy capacity. This included establishment of a standard 7:30 am start time for endoscopic procedures, addressing factors that impact on-time starts, minimization of short term and same day cancellations by strategic timing and content of pre-registration calls, educational activities with pre-registration staff to ensure consistency in patient instructions. There has been tracking of activity and assessment of procedure turn-over time to identify and correct bottlenecks.

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DIVISION OF GASTROENTEROLOGY AND LIVER DISEASE 2015-2016

Percent change from same month of prior year

Month Office Visits Procedures

July 25% 0.30%

August 46% 0%

September 34% 2.5%

October 45% 23%

November 53% 32%

December 35% 32%

January 41% 31%

February 57% 50%

March 47% 53%

April 35% 31%

May 37% 36%

June 93% 49%

Total FY16 42% 28%

Figure 1

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QUALITY IMPROVEMENTCare DeliveryThere was recognition of the need to decrease wait time for new appointments to maintain and enhance patient base. Increased productivity was leveraged to decrease wait time for office appointments. Prior to implementation of divisional productivity plan, office wait time on July 1, 2015 was determined to be 65 business days. Modelling, based upon clinical productivity expectations, and resulted in projections for a decrease in the wait time for new patient appointments. On June 1, 2016, wait time was 19 days. This change represented a 71% decrease in patient wait time for appointments (Figure 2).

Figure 2

70

60

50

40

30

20

10

June July FebruaryJanuaryDecemberNovemberOctoberSeptemberAugust March April May

0

ProjectedActual

Wait time to new patient visit, business days

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Clinical Collaboration and InnovationDivision of Gastroenterology and Liver Diseases developed collaborative and innovative clinical activities with other specialties and departments. These included establishment of regional expertise in a new endoscopic procedure, creation of a maternal-fetal medicine and GI program for high risk pregnancies, and collaboration with the Ruth Paul Hereditary Cancer Program of the Division of Hematology and Oncology.

Peroral Endoscopic MyotomyPeroral Endoscopic Myotomy (POEM) has been developed in the context of natural orifice transluminal endoscopic surgery as a minimally invasive procedure that is used for treatment of achalasia. There are few institutions with the expertise, with only approximately 35 centers in the nation performing the procedure. The Division of Gastroenterology and Liver Diseases in collaboration with the Department of Surgery has established regional expertise in this procedure, performing more than any other institution in the Washington, D.C. area.

Additionally, the endoscopic expertise established for the treatment of achalasia, resulted in the only reported performance of endoscopy pyloric myotomy in the nation. Notably, GW was featured at the American College of Gastroenterology for successfully applying the endoscopic technique and advancing treatment for refractory diabetic gastroparesis.

EDUCATIONEducational efforts have expanded in volume, scope and quality in the medical school, internal medicine residency, and gastroenterology fellowship settings. Innovations in training were implemented in the fellowship training program. The educational activities have extended to include endoscopic education to the Department of Surgery. The faculty physicians were integral in the newly developed gastroenterology curriculum in the Physician Assistants program.

Medical SchoolThe gastroenterology curriculum was restructured and revised to reflect the LCME requirements of increased clinical focus, case-based teaching, with utilization of varied didactic techniques. The entire faculty was involved in revising the curriculum. The lectures were well received by the medical students who offered uniformly positive evaluations. Members of the faculty have longitudinal commitments to small group education of pre-clinical students. Additionally, members of the division have supervised 8 CAP students and 6 practice of medicine (POM) students throughout the year. Research opportunities have also been offered to the medical students through a clinical and research elective. During the past year, medical students have been co-authors of 19 abstracts, 2 medical algorithms published in textbooks, 4 book chapters and 2 refereed manuscripts. The medical students presented their research at GW Research Day the American College of Gastroenterology annual meeting and the annual Advances in Inflammatory Bowel Disease conference. Two student-abstracts were among the 20 selected as featured abstracts from >2500 submitted abstracts at the American College of Gastroenterology annual meeting.

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GASTROENTEROLOGYInternal Medicine ResidencyResearch opportunities for internal medicine residents. During the past year, internal medicine residents have been co-authors of 20 abstracts, 1 algorithm published in a textbook, 4 book chapters and 1 refereed manuscript. The internal medicine residents presented at regional conferences, Digestive Disease Week, American College of Gastroenterology, the annual Advances in Inflammatory Bowel Disease and the International Conference on Coagulopathy of Liver Diseases. Two of the abstracts presented by internal medicine residents were poster award winners.

Gastroenterology FellowshipGastroenterology division has 7 current fellows under the leadership of Dr. Matthew Chandler. The entire gastroenterology curriculum was revised to optimize learning through self-study, didactic lectures, multidisciplinary seminars, enhanced endoscopic education. The program developed and implemented an academic half-day, which consolidates faculty-led teaching in the quantifiable didactic time free of service responsibilities. The fellows are also excused from clinical responsibilities (which are then covered by faculty) to enhance learning.

The Division of Gastroenterology developed and formalized a mentorship program to guide and monitor progress through the fellowship. The assigned one-on-one mentorship program is unique, with no other program in the nation incorporating a similar program within their fellowship. The program has been well received by the fellows. Information about mentoring within gastroenterology training was published and presented at the American College of Gastroenterology and at the Innovations in Medical Education.

Research opportunities are available for the fellows in the Division of Gastroenterology and Liver Diseases. During the past year, the gastroenterology fellows have been co-authors of 13 abstracts, 7 algorithms published in a textbook, 13 book chapters and 2 refereed manuscript. The internal medicine residents presented at regional conferences, Digestive Disease Week, American College of Gastroenterology, the annual Advances in Inflammatory Bowel Disease and the International Conference on Coagulopathy of Liver Diseases.

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RESEARCHThe Division of Gastroenterology and Liver Diseases is developing a research focus that concentrates on colonoscopy outcomes, inflammatory bowel disease and health care disparities. The collaborative research activities have involved students, internal medicine residents, and gastroenterology fellows. There has been collaboration with the members of the Department of Surgery and the Rodham Institute. Additionally, members of the division are involved on the national level, with the development of an ergonomics research project for the American Gastroenterological Association.

During the Division of Gastroenterology and Liver Diseases published 41 abstracts, 7 algorithms, 14 book chapters and 7 refereed manuscripts. There were 6 regional presentations, 30 national presentations, and 1 international presentation. Two were selected as featured abstracts at a national medical conference and 4 were selected as poster winners.

PUBLICATIONS• Drs. Marie Borum, Gastroenterology, Jessica Davis, PGY4, and Brandon Rieders,

PGY3, published, “Clinical Practice Patterns Suggest Female Patients Prefer Female Endoscopists” in Journal of Digestive Diseases and Sciences.

• Drs. Tim Dougherty, Marie Borum, Gastroenterology; Dr. Justin Ertle, PGY 2; Dan Gaballa and Shreya Chablaney, medical students, on their abstract, Primary Care Providers are Vital to Carrying out Hepatitis C Screening, being accepted for presentation at the American College of Physicians Annual Meeting, May 2016.

• Chandler M, Borum ML. Effects of implementing 1-on-1 Mentorship on Development of Medical Knowledge in a Gastroenterology Fellowship Program. American Journal of Gastroenterology 110 (supplement 1); S965, October 2015.

• Chandler M, Borum ML. Mentorship Programs Can Provide an Opportunity to Enhance Fellowship Education in ACGME Core Competencies. American Journal of Gastroenterology 110 (supplement 1); S966, October 2015.

• Borum ML, Chandler M. Learning from the Mentee: A Potentially Underappreciated Outcome of Faculty Mentoring in Gastroenterology Fellowship Programs. American Journal of Gastroenterology 110 (supplement 1); S971, October 2015.

• Borum ML, Chandler M. Gastroenterology Faculty and Fellows Identify the Benefits of a Mentoring Program. American Journal of Gastroenterology 110 (supplement 1); S971-972, October 2015.

• Chandler M, Borum ML. The Benefits and Challenges of a Formal Mentoring Program in a Gastroenterology Fellowship. Innovations in Medical Education Conference, Los Angeles, California, February 2016.

• Lattimer L, Chandler M, Borum ML. Hispanics and Inflammatory Bowel Disease. Inflammatory Bowel Diseases 2015 May: 21 (5): 1214-1218. Doi: 10.1097

• Bashir S, Borum ML. Review of Clinical and Endoscopic Features of Metastatic Tumors of the Gastrointestinal Tract. Journal of Digestive Endoscopy 2015 April; 6 (1): 11-14. DOI: 10.4103/0976-5042.155233

• Chia R, Borum ML. African Americans May Access the Emergency Department for Inflammatory Bowel Disease Care More Often Than Whites. Inflammatory Bowel Diseases 2015 August 21 (8):E14.

• Davis J, Rieders B, Borum ML. Clinical Practice Patterns Suggest Female Patients Prefer Female Endoscopists. Digestive Diseases and Sciences 2015 Oct, Vol 60 (10); 3149-3150.

• Khanijow V, Prakash P, Emsellem H, Borum M, Doman D. Sleep Dysfunction and Gastrointestinal Diseases. Gastroenterology and Hepatology 2015 December 11 (12): 817-825.

BOOK CHAPTERS• Jakhete N, Ciampa B, Borum ML. Angiodysplasia, in The 5-Minute Clinical

Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Jakhete N, Al-Shahrani A, Borum ML. Prophyria Cutanea Tarda, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Jakhete N, Myint A, Borum ML. Chronic Diarrhea, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Prakash P, Al-Shahrani A, Borum ML. Fecal Impaction, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Prakash P, Myint A, Borum ML. Gastric Polyp, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Grimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Prakash P, Alencherry B, Borum ML. Sideroblastic Anemia, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Prakash P, Glass J, Borum ML. Salmonella Infection, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

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• Prakash P, Davis D, Borum ML. Pruritus Ani, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Prakash P, Al-Shahrani A, Borum ML. Acute Diarrhea, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Prakash P, Alencherry B, Borum ML. Ischemic Colitis, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Lee WJ, Zeddun S, Borum ML. Intussussception, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Davis J, Borum ML. Acute Peritonitis, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

• Myint AS, Lee WJ, Borum ML. Choledocholithiasis, in The 5-Minute Clinical Consult Eds. Domino F, Baldor R, Golding J, Frimes JA, Taylor JS, Philadelphia: Lippincott Williams & Wilkins, 2016.

ABSTRACTS• Waseem N, Zeddun S, Brody F, Borum ML. Successful laparoscopic assisted

gastric per oral endoscopic myotomy (G- POEM) in refractory diabetic gastroparesis. American Journal of Gastroenterology 110 (supplement 1); S203, October 2015.

• Waseem N, Zeddun S, Brody F, Borum ML. Successful laparoscopic assisted gastric per oral endoscopic myotomy (G- POEM) in refractory diabetic gastroparesis. American Journal of Gastroenterology 110 (supplement 1); S203, October 2015.

• Corinaldi MM, Corinaldi MG. Borum ML. Trying to Stay Healthy Can Sometimes Make you Sick if you have Celiac Disease: Vitamins at Mass Market Retail and Warehouse Stores Often Contain Gluten. American Journal of Gastroenterology 110 (supplement 1): S1013, October 2015.

• Waseem N, Zeddun S, Brody F, Borum ML. Successful laparoscopic assisted gastric per oral endoscopic myotomy (G- POEM) in refractory diabetic gastroparesis. American Journal of Gastroenterology 110 (supplement 1); S203, October 2015.

• Corinaldi MM, Corinaldi MG. Borum ML. Trying to Stay Healthy Can Sometimes Make You Sick if you have Celiac Disease: Vitamins at Mass Market Retail and Warehouse Stores Often Contain Gluten. American Journal of Gastroenterology 110 (supplement 1): S1013, October 2015.

• Rieders B, Davis J, Lettimer L, Khanijow Y, Taneja S, Myint A, Al-Shahrani AA, Nesserdine S. Borum ML. A high stakes learning environment. Fellow-performed colonoscopies are associated with Lower ADRS. University of Virginia Annual Conference of Liver Disease and Gastroenterology.

• Davis J, Chun A, Borum ML. Mesocaval Shunting for Refractory Esophageal Varices in Cirrhosis Complicated by Chronic Portal Vein Thrombosis. University of

Virginia Conference of Liver Diseases, Charlottesville, Virginia, 2015. • Davis J, Rieders B, Lattimer L, Khanijow V, Nassereddine S, Myint A, Al-Shahrani

AA, Taneja S, Borum ML. Ladies First: do Female Patients Prefer Female Endoscopists? Gastrointestinal Endoscopy 81(5) supplement: AB331, May 2015.

• Davis J, Rieders B, Al-Shahrani AA, Nassereddine S, Lattimer L, Khanijow V, Taneja S, Myint A, Borum ML. Higher Adenoma Detection Rates in Caucasians at an urban center: do differences in preparation play a role? Gastrointestinal Endoscopy 81 (5) supplement: AB219, May 2015.

• Rieders B, Davis J, Khanijow V, Taneja S, Myint A, Al-Shahrani AA, Nassereddine S, Lattimer L, Borum ML. Does experience matter? Increased ADRs in experienced gastroenterologists may reflect patient population as well as technical skill. Gastrointestinal Endoscopy 81 (5) supplement, May 2015.

• Taneja S, Hejazifar N, Dougherty T, Borum ML. There are eyes in team -- and they affect adenoma detection. American Journal of Gastroenterology 110 (supplement 1); S619, October 2015.

• Taneja S, Hejazifar N, Dougherty T, Borum ML. Access to care may narrow ethnic disparities in colorectal adenomas. American Journal of Gastroenterology 110 (supplement 1); S614, October 2015.

• Taneja S, Hejazifar N, Dougherty T, Borum ML. Gastroenterology fellows are effective in preventing colorectal cancer by colonoscopy. American Journal of Gastroenterology 110 (supplement 1); S614, October 2015.

• Nessereddine S, Taneja S, Hejazifar N, Dougherty T, Borum ML. Intervals Matter: Increased Rates of Colorectal Neoplasia with Delayed Surveillance. American Journal of Gastroenterology 110 (supplement 1); S618, October 2015.

• Nessereddine S, Taneja S, Hejazifar N, Dougherty T, Borum ML.Obesity does not increase adenoma prevalence: Patients should be encouraged to pursue colonoscopy. American Journal of Gastroenterology 110 (supplement 1); S617, October 2015.

• Rieders B, Davis M, Taneja S, Myint A, Nassereddine S, Lattimer L, Khanijow V, Borum ML. Breast Cancer as an individual risk factor for increased adenoma detection: A retrospective study. American Journal of Gastroenterology 110 (supplement 1); S626, October 2015.

• Hajazifar N, Taneja S, Ali MA, Borum ML. Adenoma Detection Rate May Decline for Screening Colonoscopy Cases Performed Late in the Day. American Journal of Gastroenterology 110 (supplement 1); S676, October 2015.

• Hajazifar N, Taneja S, Ali MA, Borum ML. Adenoma Detection Rate Does Not Differ in Screening Colonoscopies Performed in the Morning or Afternoon. American Journal of Gastroenterology 110 (supplement 1); S672, October 2015.

• Hajazifar N, Taneja S, Ali MA, Borum ML. Mid-Day Nadir in Adenoma Detection Rates Suggests that Scheduled Endoscopists’ Breaks Can Optimize Colorectal Cancer Screening. American Journal of Gastroenterology 110 (supplement 1); S677, October 2015.

• Bashir S, Prakash P, Wazzan M, Alabbas B, Borum ML. A Rare Presentation of an Aortoenteric Fistula After Aneurysm Repair. American Journal of Gastroenterology 110 (supplement 1); S471, October 2015.

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• Prakash P, Lesky L, Dougherty T, Borum ML. Hyperbaric Oxygen is effective for treatment of pneumatosis intestinalis due to systemic sclerosis. American Journal of Gastroenterology 110 (supplement 1); S463, October 2015.

• Waseem N, Nessereddine S, Pavle A, Zhang J, Dougherty T, Borum ML. Race does not affect the Prevalence of Sporadic Adenomas in Inflammatory Bowel Disease. Inflammatory Bowel Diseases, vol 22 (supplement): S29, March 2016.

• Caldis M, Waseem N, Pavle A, Baig K, Chablaney S, Alabbas B, Wazzem M, Dougherty T, Borum ML. Sessile Serrated Adenoma Prevalence in Inflammatory Bowel Disease Patients is Independent of Age. Inflammatory Bowel Diseases, vol 22 (supplement): S26, March 2016.

• Rieders B, Davis J, Lettimer L, Khanijow Y, Taneja S, Myint A, Al-Shahrani AA, Nesserdine S. Borum ML. A high stakes learning environment. Fellow-performed colonoscopies are associated with Lower ADRS. University of Virginia Annual Conference of Liver Disease and Gastroenterology.

• Davis J, Chun A, Borum ML. Mesocaval Shunting for Refractory Esophageal Varices in Cirrhosis Complicated by Chronic Portal Vein Thrombosis. University of Virginia Conference of Liver Diseases, Charlottesville, Virginia, 2015.

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GENERAL INTERNAL MEDICINEAPRIL BARBOUR, MD, MPHAssociate Professor of Medicine, Division Director

2150 PENNSYLVANIA AVENUE FACULTYSharon Baratz, MD, Assistant Professor of MedicineKaylan Baban, MD, Assistant Professor of MedicineBenjamin Blatt, MD, Professor of MedicineElena Boley, MD, Associate Clinical Professor of MedicineLetitia Carlson, MD, Assistant Clinical Professor of MedicineJillian Catalanotti, MD, Associate Professor of MedicineAileen Chang, MD, Assistant Professor of MedicineZayn Copeland, MD, Assistant Professor of MedicineMichael Czarnecki, DO, Associate Professor of MedicineJehan (Gigi) El-Bayoumi, MD, Professor of MedicineAndrea Flory, MD, Assistant Professor of MedicineGregg Furie, MD, Assistant Professor of MedicineMarijane Hynes, MD, Clinical Professor of MedicineRobert Jablonover, MD, Assistant Professor of MedicineVimala Jayanthi, MD, Assistant Professor of MedicineSeema Kakar, MD, Associate Clinical Professor of MedicineSheena P. Khurana, MD, Assistant Professor of MedicineMia Marcus, MD, Associate Clinical Professor of MedicineChad Henson, MD, Assistant Professor of MedicineMatthew Mintz, MD, Associate Professor of MedicineBrad Moore, MD, Associate Professor of MedicineChavon Onumah, MD, Assistant Professor of Medicine

Mihir Patel, MD, Assistant Professor of MedicineDavid Popiel, MD, Assistant Professor of MedicineAdam Possner, MD, Assistant Professor of Medicine W. Scott Schroth, MD, Associate Professor of Medicine Paul Silver, MD, Associate Professor of MedicineAmy Stone, MD, Assistant Professor of MedicineZohray Talib, MD, Associate Professor of Medicine Ginger Winston, MD, Associate Professor of Medicine

2300 M STREET INTERNAL MEDICINE PHYSICIANSNatasha Ang, MD, Assistant Clinical Professor of MedicineElizabeth Bluhm, MD, Assistant Clinical Professor of MedicineCatherine Boinest, MD, Assistant Professor of MedicineBonita Coe, MD, Associate Clinical Professor of MedicineRobert Kruger, MD, Associate Clinical Professor of MedicineAmirala Pasha, DO, Assistant Clinical Professor of Medicine (Regular Faculty appointment effective 7/1/16)Farzana Walcott, MD, Assistant Professor of MedicineMaram Alkhatib, MD, Clinical Instructor of Medicine

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VA FACULTYCharles Faselis, MD, Professor of Medicine, Chair VA Department of MedicineCherinne Arundel, MD, Assistant Professor of MedicineRibka Ayana, MD, Assistant Professor of MedicineNatalie Branagan, MD, Assistant Professor of MedicineDaniel Chen, MD, Assistant Professor of MedicineKatherine Chretien, MD, Assistant Professor of MedicineJames Croffoot, MD, Assistant Professor of MedicineShruti Gandhi, MD, Assistant Professor of MedicineJennifer Kerns, MD, Assistant Professor of MedicineJessica Logan, MD, Assistant Professor of MedicineSamantha McIntosh, MD, Assistant Professor of MedicineDragica Mrkoci, MD, Assistant Professor of MedicineRobin Peck, MD, Assistant Professor of MedicineNazia Qazi, MD, Assistant Professor of MedicineJoanna Rosen, MD, Assistant Professor of MedicineShaman Singh, MD, Assistant Professor of MedicineElizabeth Trimble, MD, Assistant Professor of MedicineMatthew Tuck, MD, Assistant Professor of MedicineVictor Wu, MD, Assistant Professor of Medicine

NPs/PAsCameron Hogg, NPElizabeth Kirby, NPAlison Donovan, NPElizabeth Hatcher, NPErica Deam, NPJane Wu, PAJoanna Milder, PANatalie Nicolas, RDLauren Leatherman, LICSWShelleta Pleasant, LICSW

MASTER TEACHER LEADERSHIP DEVELOPMENT PROGRAM CANDIDATELalit Narayan, MD, Visiting Instructor of Medicine

GWUH CHIEFS FY 16 Erin Vipler, MD Jessica Davis, MD Courtney Paul, MD Yevgeniy Vayntraub, MD, VA ChiefAdam Kittai, MD, VA ChiefMortada Shams, MD, Fairfax Chief

DGIM has had another excellent year and contributed substantially to the mission of the University in education, scholarship and service. While we are primarily Clinician Educators, our newly hired Clinician Investigators are starting to be productive.

EDUCATION/TEACHING Preclinical: Currently 17 faculty teach in the first year course, second year course or both. CSR is an intensive small group discussion based course that meets weekly. Faculty facilitate discussions, manage learning sessions, directly observe physical exam and communication skills and provide ongoing feedback and instruction over the course of 16 months. Five faculty teach in the Professional Development course (which is also a small group, discussion based course).

Clinical: Thirteen faculty precept students during one or more of their clinics during the 4 week- primary care clerkship. Seventeen faculty (only 2 of which also precept in the clerkship) mentor students in the Longitudinal Primary Care Curriculum, which is a yearlong commitment to have a student in clinic ½ a week.

GENERAL INTERNAL MEDICINE

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GRADUATE MEDICAL EDUCATIONClinical Competency Committees: Five faculty serve on one of the three CCCs, one of whom chairs a committee (Dr. Henson). These faculty are responsible for reviewing the evaluations of their assigned residents (5-6) and presenting them to the committee. They also meet with each of their residents twice yearly to review their progress and set individual goals.

Clinic Preceptors: Eighteen faculty precept in resident clinic 1-3 times a week. They are responsible for directly observing their residents and providing immediate feedback in clinic. They also provide summative evaluations twice yearly. They all participate in weekly didactics on a rotating schedule.

Ambulatory Curriculum: overseen by Dr. Barbour with the chief resident.

Recurring didactic content:• Primary Care Journal Club, Dr. Barbour, Dr Khurana and Dr.

Burstin, weekly• Intern Curriculum: Dr. Henson 5-6 core lectures given

weekly to entire intern class• Medical Education Series, Dr. Barbour, Dr. Henson, 2

workshops each year• Physical Diagnosis Series, Dr. Silver, 2 workshops each year.• Community Health Curriculum, Dr. Popiel 1 -2 workshops

a year• Cancer Survivorship Curriculum, Dr. Barbour, 1 workshop a

year• HIV in Primary Care Curriculum, Dr. Onumah, Dr. Henson

(in development)• Medical Legal Partnership Curriculum, Dr. Barbour with DC

Legal Aid (in development)

SCHOLARSHIP / RESEARCHClinician Investigators: All 3 of the physicians hired in the past 2 years as Clinician Investigators in DGIM have successfully received small pilot grants/ funding and are well prepared to apply for larger grants. • Dr. Winston has had several publications based on her work

in social networks. • Dr. Walcott won a prestigious young investigator award

from ASCO and has brought together faculty from SMHS and SPH to form a research interest group.

• Dr. Chang has developed an international network related to vector borne illnesses.

• Dr. Talib has had a number of publications in the past year through her work in global health.

• Both Dr. Walcott and Dr. Winston have received secondary appointments in the School of Public Health.

GrantsCongratulations to...• Dr. Aileen Chang, General Internal Medicine, on her grant

from the Rheumatology Research Foundation titled, “A Pilot Study of the Pathogenesis of Chikungunya Arthritis in the Americas”.

• Dr. Farzana Walcott, General Internal Medicine, on her grant from the Conquer Cancer Foundation titled, “Metabolomics Profiles of Metformin Treatment in Li-Fraumeni Syndrome”.


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CLINICAL INNOVATIONSHospital Discharge Clinic: Weekly resident run clinic staffed by Dr. Henson. This clinic is available to all DGIM patients who are recently discharged but also GWU Hospital patients that are deemed high risk for readmission. The curricular component for the residents focuses on good transitions and safe discharges.

Pre-op Clinic: Weekly resident clinic staffed by Dr. Patel. This clinics focuses on peri-operative management and pre-operative risk stratification and testing and is open for all DGIM patients.

Cancer Survivorship Clinic: This clinic focuses on providing a Survivorship Care Plan for all patients within 6 month of completing treatment. As part of this clinic, we have developed a Survivorship Research Interest group of clinicians and scientists across the Medical Center. Dr. Czarnecki works in the Thriving after Cancer (TAC) clinic which sees adult survivors of pediatric cancers and is a collaborative effort with CNMC. Dr. Walcott works with Elizabeth Hatcher, NP in the Adult Survivorship clinic and attends all the Cancer Committee meetings as part of that effort.

Weight Management Clinic: Dr. Hynes is the clinic director. Preventive Medicine Clinic: Dr. Baban has 2 clinics a week focusing on stress management, smoking cessation, lifestyle interventions and dietary interventions.

AWARDSDr. Robert Wilkinson was selected to receive the Outstanding Volunteer Clinical Teacher Award from the American College of Physicians.

Dr. Richard Simons, Professor of Medicine and Senior Associate Dean for MD Programs at the GWSMHS, has been elected to serve a two-year term as Regent of the American College of Physicians.

Dr. Brandon Rieders, PGY 2, who won the award for the best poster at the Annual Conference of Liver Disease and Gastroenterology at the University of Virginia. Dianne Thompson, MD, Internal Medicine resident, and Sheena Khurana, MD, Internal Medicine faculty, were awarded the 2015 Rodham Institute Academic Community Collaborative Award for with Wholesome Waves, “Empowering Physicians to Address Health Disparities Related to Food Insecurity”. Wholesome Waves is a National non-profit organization dedicated to providing a just and sustainable food system.

Congratulations to Joseph Delio, MD, PGY 2, as he was awarded the GME Research, Quality Improvement Award for his work, “Improving adherence to the United States Preventive Services Task Force screening and immunization guidelines among residents at the internal medicine clinic with the GWU MFA group”.


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Dr. Suneeta Ganji, PGY3, will be celebrated at the American College of Physicians Internal Medicine Meeting in May as a Young Achiever. This is a great achievement, especially for a young achiever.

Dr. Catherine Boinest, General Internal Medicine, was awarded the 2015 Vitals Patients’ Choice Award.

Dr. Farzana Walcott, General Internal Medicine, was selected to receive a 2016 Young Investigator Award from the American Society of Clinical Oncology (ASCO).

Dr. Andrea Flory, General Internal Medicine, won a Distinguished Teacher Award from the Medical School.

ACP NATIONAL 2016 AWARD WINNERSCarole E. Horn, MD, Associate Clinical Professor, awarded the Ralph O. Claypoole Sr. Memorial Award for Devotion of a Career in Internal Medicine to the Care of Patients, this award is given to an outstanding practitioner of internal medicine who has devoted his or her career to the care of patients.

Alan W. Stone, MD, FACP, Clinical Professor, awarded the Arnold P. Gold Foundation ACP Award for Medical Humanism, this award is given to someone who demonstrates compassion and empathy in the delivery of patient care; shows respect for patients, families and co-workers; demonstrates cultural sensitivity in working with patients and family members of diverse backgrounds; and engenders trust and confidence.

Robert S. Wilkinson Jr., MD, MACP, Professor Emeritus, awarded the Outstanding Volunteer Clinical Teacher Award, this award is given to someone who consistently volunteered his or her services to teach medical students and residents outside of his or her academic responsibilities. This individual should have demonstrated outstanding teaching prowess, displayed exemplary characteristics of care and concern for individual patients at the bedside, and served as a role model and mentor.

ACP DC CHAPTER MEETING, SPRING 2015Drs. Lei Lynn, PGY 1, Erica McBride, PGY2, and Omar Siddique, PGY 2, took home 1st place prizes for podium presentations in the categories of research and in clinical vignettes.

Dr. Steven Quinn, PGY3, won the award for best GW research poster

Drs. Betsy Kidder, PGY1, Nika Safaie, PGY2, and co-author Niharika Tipirneni, PGY3, tied to win the award for best GW clinical vignette poster.

PUBLICATIONS• Dr. Ginger Winston, Division of General Internal Medicine, manuscript, “The

Relationship between Social Network Body Size and the Body Size Norms of Black and Hispanic Adults” was published in Preventive Medicine Reports Journal.

• Drs. Talal Alzahrani, PGY2, Dana Kay, PGY2, Saeed Alqahtani, Neurology resident, Yamane Makke, Neurology resident, Linda Lesky, Hospital Medicine, and Mohamad Koubeissi, Neurology, published “Levetiracetam-induced Pancytopenia” in Epilepsy &Behavior Case Reports.

• Drs. Kanika Gupta, PGY2, and John Tiu, PGY1, for having their manuscript,” The promising role of nivolumab in renal cell cancers,” accepted for publication in Cancer Biology & Therapy.

• Drs. Jillian Catalanotti, James Croffoot, and prior chief resident, Laura Perry published, “Testing for Malignancy: A Teachable Moment”, in JAMA Internal Medicine.


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GERIATRICS AND PALLIATIVE CAREKATALIN ROTH, MD, JDAssociate Professor of Medicine, Division Director

FACULTYTania Alchalabi, MD, Assistant Professor of MedicineDanielle Doberman, MD, Assistant Professor of Medicine; Director, Palliative Medicine Program; Assistant Fellowship Director, Palliative MedicineRobert Jayes, MD, Associate Professor of Medicine; Medical Director, House Call ProgramMikhail Kogan, MD, Assistant Professor of Medicine; Medical Director, GW Center for Integrative MedicineAngela Lee, MD, Assistant Clinical Professor of Medicine - Promoted to Associate Clinical Professor of Medicine 7/1/16Tahira Lodhi, MD, Assistant Clinical Professor of MedicineChristina Prather, MD, Assistant Professor of MedicineLeslie Pierce, MD, Associate Clinical Professor of MedicineChristina Puchalski, MD, Professor of Medicine; Director, GW Institute for Spirituality and Health

VA FACULTYElizabeth Cobbs, MD, Professor of Medicine; VA Chair of GeriatricsAli Ahmed, MD, Professor of MedicineKaren Blackstone,MD, Assistant Professor of MedicineAnca Dinescu, MD, Assistant Professor of MedicineNadine Dubowitz, MD, Assistant Professor of MedicineRobert Kaiser, MD, Associate Professor of Medicine

Raya Kheirbek, MD, Associate Professor of MedicineNickie Lepcha, MD, Assistant Professor of MedicineSonika Pandey, MD, Assistant Professor of Medicine

NPs/PAsSafiya Steward, NPLaurie Wilson, NPTrish Olin, PA

CLINICALMemory Disorders Drs. Prather and Alchalbi have launched a new and improved Memory Clinic which builds upon the practice started by Dr. Cooper.

Outpatient Palliative Under the new Cancer Center leadership, Drs. Puchalski, Roth and Doberman are creating a new Center for Palliative Medicine and Spirituality which aspires to become a leader in research as well as palliative care.

Dr. Roth was recently elected to the Board of Foggy Bottom/West End Village.

Dr. Roth and Dr. Jayes continue to work with the BreadfortheCity DC Asylum Clinic helping refugees in the DC area.

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HOSPITALWorking to prevent delirium in hospitalized elders, Dr. Prather has implemented a Sleep Promotion order set for identified patients to reduce incident delirium of subsequent complications.

Dr. Angela Lee has been working with a group to develop a protocol for Advanced Care Planning in the ED. EDUCATIONSOMTrish Olin and Laurie Wilson are active preceptors for CAP medical students and for NP and PA students.

The Integrative Medicine Track Program in School of Medicine continues to be a vibrant program that has been updated to include Bread for the City volunteer opportunities. We have also added partnership with Virginia College of Oriental Medicine, Unity Clinics, and Maryland University of Integrative Health.

Dr. Prather and Dr. Lodhi organized a new 30 hour curriculum Geriatrics course for the PA Program, in which Drs Alchalabi, Roth and Jayes also participated.

Dr. Doberman Developed new, 2 week Trauma-service PA curriculum for new-PA trauma fellowship at GWUH hospital.

Dr. Lodi has developed a new longitudinal clinical experience in Assisted Living for the primary care residents.

Dr. Prather has developed enhanced curriculums for inpatient geriatric consultation and for memory disorders.

Dr. Prather has developed a five week geriatric conference curriculum on transitions for all residents on the 4+1 schedule.

FellowshipGeriatrics has 5 fellows under the leadership of Dr. Elizabeth Cobbs.

Hospice and Palliative Care has 5 fellows under the leadership of Dr. Karen Blackstone (VA).

Our fellowship emphasis on education is reflected in the expansion of our palliative fellowship from 2 to 4 fellows per year and the fact that we have filled all open slots for both Geriatrics and Palliative fellows for 2016-2017.

5 Integrative Medicine Fellows have been trained in 2016-2017 year and will be ready to take ABOIM certification exam starting in fall 2017.

Dr. Kogan is the online GW Integrative Medicine Fellowship has received accreditation by ABOIM (American Board of Integrative Medicine), under auspices of ABPS.

In addition, Dr. Kogan is a leader in The Chicago VA/GW Integrative Medicine Fellowship Pilot program to train 10 primary care doctors in Chicago VA was funded and was approved by ABOIM. The long term goal is to create national VA training fellowship in partnership with GW.

GERIATRICS AND PALLIATIVE CARE

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GERIATRICS AND PALLIATIVE CARE

INTERNATIONAL WORKDominican Republic- Katalin Roth (Geriatrics) for the past twelve years has volunteered with Somos Amigos Medical Missions, which staffs a small medical and dental clinic in rural Dominican Republic, near the Haitian border. They provide primary care to local residents, adults and children, many of whom she has come to know well. This June will mark her 12th trip to Naranjito, a hamlet set among farms and steep hillsides. Hard work rewarded by comradery, simple food, mountain air, and practicing medicine on behalf of people who really need us.

PUBLICATIONS• Puchalski CM, Jafari N: Acknowledging the Person in the Clinical Encounter:

Whole Person Care for Patients and Clinicians Alike. Commentary on Chochinov et al. Journal of pain and symptom management. 2015;49(6): 973.

• Puchalski CM, Handzo G, Ferrell B. Religious Conflicts: Decision Making When Religious Beliefs and Medical Realities Conflict. Journal of Pain and Symptom Management. 2016;51(2).

• Puchalski CM, Vitillo RJ, Jafari N: Global Network for Spirituality and Health (GNSAH): Seeking More Compassionate Health Systems. Journal for the study of science and spirituality. 2016; 6(1): 106–112.

BOOK CHAPTERS• Lolak S, Minor D, Jafari N, Puchalski C. Chapter 17: Spirituality and spiritual

interventions in Mental Health and Aging; Contributor In: Complementary, Alternative, and Integrative Interventions for Mental Health and Aging Lavretsky, Sajatovic, Reynolds, 2015, Oxford University Press. 257-271. (Please replace this with the one that you currently have in her CV)

• Puchalski, C. Foreword in: Dorman WE. Restoring the Healer: Spiritual Self-Care for Health Care Professionals, 2016; Templeton Press.

• Jafari N, Roth K, Puchalski C. Spiritual Care in Geriatric Medicine; Contributor In: 7th edition of Hazzard’s Principles of Geriatric Medicine and Gerontology; Jeffrey Halter, Joseph Ouslander, Stephanie Studenski, Kevin High,et.al. 2016; McGraw-Hill. (In Press)

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HEMATOLOGY & ONCOLOGYGW CANCER CENTER

EDUARDO SOTOMAYOR, MDProfessor of Medicine, Director of the GW Cancer Center,Director of the Division of Hematology/Oncology

FACULTYJames Ahlgren, MD, Professor of Medicine and PharmacologyKhaled el-Shami, MD, Assistant Professor of MedicineRebecca Kaltman, MD, Assistant Clinical Professor of MedicineLauren Mauro, MD, Assistant Professor of MedicineKavita Natrajan, MD, Associate Professor of MedicineFrederick Rickles, MD, Clinical Professor of MedicineRobert Siegel, MD, Professor of MedicineImad Tabbara, MD, Professor of Medicine; Director, Blood and Bone Marrow Transplant ProgramJeanny B. Aragon-Ching, MD, Associate Professor of Medicine

VA FACULTYAnita Aggarwal, MD, Associate Professor of MedicineJoao Ascensao, MD, Professor of MedicineCharles Hesdorffer, MD, Professor of MedicineDalia Mobarek, MD, Assistant Professor of Medicine

NPsAmy Hillsman, NPAlice Gilhool, NP

UPCOMING FACULTYJianqing Lin, MD- Associate Professor of Medicine – 7/1/16 (Genitourinary Malignancies)

Due to the establishment of the GW Cancer Center on July 1st, 2015, the Division of Hematology and Oncology in the Department of Medicine has undergone significant changes to align itself with the vision and goals of the GW Cancer Center.

First, Dr. Robert Siegel stepped down as Division Director and Dr. Eduardo M. Sotomayor, Director of GW Cancer Center was appointed as Interim Division Director. Second, in his new role Dr. Sotomayor has been charged to expand the current focus of the Division in Clinical service and Education into state-of-the-art clinical cancer research. To accomplish this goal, the Division has embarked in an aggressive recruitment of mid-career clinical investigators that will bring a broad portfolio of cancer clinical trials. A total of 11 FTEs have been committed for the recruitment of clinical investigators, including the Associate Center Director for Clinical Investigations and a permanent new Division Director. Third, the clinical service of our current Faculty is being transitioned into a model that is more disease-oriented in order to align our Division with the goal of the Cancer Center to seek NCI-designation in the near future.

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RESEARCH ACCOMPLISHMENTS• Establishment of the B-cell malignancies translational/

clinical research group• Establishment of the Gastrointestinal (GI) malignancies

translational/clinical research group• Establishment of the Breast cancer translational/clinical

research group• Establishment of the Head/Neck/Thyroid malignancies

translational/clinical research group• Oral presentation at the American Society of Hematology

(ASH) Annual Meeting • Submission of several federal and non-federal grants

involving Faculty from the Division of Hematology/Oncology

• Sponsored Research Agreement with a biotechnology company (Acetylon Pharmaceuticals) to support translational/clinical research in the Division of Hematology/Oncology

GRANTS AWARDED• NIH-1R01CA179062-01 (Eduardo M. Sotomayor, M.D./

Jianguo Tao, MD). “Role of specific HDACs in Mantle Cell Lymphoma Immunobiology and Therapy” 7/2016 – 6/2021

• NIH-1R01CA20648-01 (Douglas Nixon, MD/Eduardo M. Sotomayor, MD). “HIV induced anti-cancer HERV immunity in prostate, breast and colon cancers”. 7/2016 – 6/2021

• Acetylon Pharmaceuticals-Sponsored Research Agreement (Eduardo M. Sotomayor, MD) “Evaluation of the in vitro and in vivo anti-melanoma effects of the HDAC6 inhibitors ACY-241 and ACY-1215”. 7/2016-12/2017

GRANTS SUBMITTED

• NIH-P01CA130821 (PI: Lopa Mishra, MD. Co-Investigators: E. Seto, E. Sotomayor, A. Tzatzos, G. Nguyen (GWCC) and S. Li (MD Anderson). “Cellular and Molecular Mechanisms of Gastrointestinal Cancers” 1/2017 – 12/2021

• NIH (K.Crandall/Sotomayor, E) “Genomic Data Analysis Network: Specialized Genomic Data Center”

• NCI (Horvath/Seto/Sotomayor): “Nucleotide resolution integration of normal and tumor RNA and DNA with cancer clinical data”

• Melanoma Research Alliance (Villagra/Sotomayor/Weber): “Enhancing melanoma immunotherapy by using HDAC inhibitors”

• FORMA Therapeutics-Sponsored Research Agreement (Eduardo M. Sotomayor/Khaled el-Shami) “Evaluation of dual inhibition of HDAC6 and HDAC11 in T-cells to augment T-cell adoptive cancer immunotherapy”

HEMATOLOGY & ONCOLOGY

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CLINICAL ACCOMPLISHMENTSEstablishment of disease-oriented teams:

Breast CancerRebecca Kaltman and Lauren Mauro

GI MalignanciesKhaled el-Shami and James Ahlgren

Head & Neck cancerRobert Siegel and Khaled el-Shami

Other solid tumorsRobert Siegel

Hematologic MalignanciesImad Tabbara, Kavita Katrajan, Frederick Rickles, Eduardo M. Sotomayor

GU MalignanciesJianqing Lin (effective July 1st, 2016)

EDUCATION ACCOMPLISHMENT• Continued education of medical students, resident and

Hematology/Oncology fellows• 6 current fellows under the leadership of Dr. Imad Tabbara• Mentoring of Junior Faculty (Mauro, el-Shami and Katrajan)

by senior members of the Division (Tabbara and Sotomayor)• Nationally recognized Hematology/Oncology Review

Course lead by Dr. Robert Siegel• Increased attendance to review courses in Hematology

(Best of ASH) and Medical Oncology (Best of ASCO) sponsored by the Division of Hematology/Oncology

• Monthly forums to educate patients and their caregivers about specific cancers, long-term side effects and survivorship

AWARDSDr. Geraldine Schechter, Professor Emeritus, was awarded the Walter Lester Henry, Jr.,MD Award for Lifetime Teaching Excellence, which honors lifetime excellence as a teacher.


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PUBLICATIONS• Woods, DM, Sodre AL, Villagra, A, Sarniak A, Sotomayor, EM and Weber, J. HDAC

Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade. Cancer Immunol Res. 3(12) 1375-85, 2015

• Beltran, BE, Aguilar, C, Quinones, P, Morales, D, Chavez, J, Sotomayor, EM and Castillo, JJ. The neutrophil-to-lymphocyte ratio is an independent prognostic factor in patients with peripheral T-cell lymphoma, unspecified. Leukemia & Lymphoma. 57(1):58-62, 2016

• Lienlaf, M, Perez-Villarroel, P, Knox, T, Pabon, M, Sahakian, E., Powers, J, Woan, KV, Lee, C, Cheng, F, Deng, S, Smalley, KS, Montecino, M, Kozikowski, A, Pinilla-Ibarz, J, Sarnaik, A, Seto, E, Weber, J, Sotomayor, EM and Villagra, A. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Molecular Oncology. Jan 6, 2016

• Castillo, J, Beltran, BE, Miranda, R, Young, KH, Chavez, JC, and Sotomayor, EM. EBV-positive diffuse large B-cell lymphoma of the elderly: 2016 Update on diagnosis, risk-stratification, and management. Am. J. Hematol. 91:530-37, 2016

• Chavez JC, Sandoval-Sus J, Horna, P, Dalia S, Bello C, Chervenick P, Sotomayor EM, Sokol L, Shah B. Lymphomatoid granulomatosis: A single institution experience and review of the literature. In Press. Clin Lymphoma Myeloma Leuk. 2016

• Zhao, X, Lwin, T, Silva, A, Shah, B, Tao, JC, Fang, B, Zhang, L, Fu, K, Li, J, Meads, M, Jacobson, T, Silva, M, Distler, A, Zhang, L, Han, Y, Rebatchouk, D, Moscinski, L, Koomen, J, Dalton, WS, Shain, K, Michael, W, Sotomayor, EM and Tao, J. Unification of tumor microenvironment (TME) mediated and acquired Ibrutinib resistance in B-cell malignancies. Submitted. J Clin. Invest, 2016

• Sahakian, E, Chen, J, Powers, J, Cheng, X, Maharaj, K, Deng, S, Lienlaf, M, Wang, HW, Cheng, F, Sodre, AL, Distler, A, Xing, L, Perez-Villarroel, P, Wei, S, Villagra, A, Seto, E, Sotomayor, EM, Horna, P. and Pinilla-Ibarz, J. Essential regulatory role for Histone Deacetylase 11 (HDAC11) in neutrophil function. Submitted. J. Leuk. Biology, 2016

• Woods, DM, Woan, K, Wang, D, Sodre, AL, Cheng, F, Wang, Z, Chen, J, Powers, J, Pinilla-Ibarz, J, Yu, Y, Weber, J, Hancock, W, Seto, E, Villagra, A, Yu, X-Z, and Sotomayor, EM. Histone deacetylase 11 (HDAC11) function as a novel epigenetic checkpoint in T-cells by regulating Eomes and Tbet expression. Submitted. J. of Immunology, 2016

• Beltran, B, Quinonez, P, Morales, D, Malaga, JM, Chavez, JC, Sotomayor, EM and Castillo, JJ. Response and survival with chemo-immunotherapy in Epstein Barr virus-positive diffuse large B-cell lymphoma. Submitted, European Journal of Hematology, 2016

• El-Shami K, Oeffinger KC, Erb NL, Willis A, Bretsch JK, Pratt-Chapman M, et al. American Cancer Society Colorectal Cancer Survivorship Care Guidelines. CA: A Cancer Journal for Clinicians. 2015 Nov-Dec;65(6);428-55. Doi:10.3322/caac.21286. Epub 2015 Sep 8

• Reiss K, Ahuja N, Baylin S, Mauro L. A Randomized Phase II Trial of Epigenetic Therapy Following Adjuvant Treatment in Patients with Resected Pancreatic

Cancer and High Risk Recurrence. Poster Session presented at American Society of Clinical Oncology, 2015

• Kuei N, Patel N, Xu H, Wells L, Bowman L, Bora P, Natrajan K, Characteristics and Potential Biomarkers for Chronic Pain in Patients with Sickle Cell Disease. Poster Session presented at American Society of Hematology, 2015.

• Natrajan K, Kutlar A. Disorders of Hemoglobin Structure: Sickle Cell Anemia and Related Abnormalities: Chapter 49 in Williams Hematology, 9th Edition, 2015, McGraw Hill Publishers.

• Falanga A, Brenner B, Rickles FR (Guest Editors). Proceedings of the 8th International Conference on Thrombosis and Hemostasis Issues in Cancer. Preface. Thrombosis Research 2016;140:Suppl 1:ix.

• Rickles FR, Brenner B, Falanga A. International Conference on Thrombosis and Hemostasis Issues in Cancer (ICTHIC) at the peak of Adolescence – 15 years and counting. Thrombosis Research, 2016;140:Suppl 1: S99-S102.

• Aragon-Ching JB, Siegel RS, Frazier II H, Andrawis R, Hendricks F, Phillips M, et al. Circulating Tumor Cells in Biochemical Recurrence of Prostate Cancer. Clinical Genitourinary Cancer 2015 Oct 13(5) e341-5, doi10.10 16

• Sadeghi N, Li N, Taheri M, Easley, S, Siegel RS, Neo-adjuvant Chemotherapy and Transoral Surgery as a Definitive Treatment for Oropharyngeal Cancer: A Feasible Novel Approach. ACCEPTED, Head & Neck: Journal for the Sciences & Specialties of the Head and Neck

• Mittelman M, Svorai-Litvak S, Oster HS, Krigner I, Siegel RS, Myelodysplastic syndromes (MDS), then and now: A comparison of two patient cohorts, 30 years apart, Department of Medicine, and Institute of Hematology, Tel Aviv Sourasky Medical Center, Sackler Medical Faculty, Tel Aviv University and the Division of Hematology and Oncology, The George Washington University Medical Center, Washington DC. SUBMITTED, American Journal of Hematology

• Patel N, Shaban A, Tabbara IA: Emerging Therapies in Cytogenetically Normal Acute Myeloid Leukemia. Annals of Hematology/Oncology, 2015, 2:6

• Yu EM, Kittai A, Tabbara IA: Chronic Lymphocytic Leukemia: Current Concepts. Anti-Cancer Research, 35:5149-5166 (2015)

• Pant MK, Alshenawy W, Alrajjal A, Alrobeh H, Tabbara IA, Mantle Cell Lymphoma: Current Concepts. Journal of Hematology and Thromboembolic Diseases, 2015, 3:4


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ABSTRACTS• Hongwei Wang, Fengdong Cheng, Jie Chen, James

Bradner, Alejandro Villagra, Jianguo Tao, Eduardo M. Sotomayor. “JQ1, a Selective Bromodomain Inhibitor, augment the immunogenicity of Mantle cell lymphoma by influencing the expression of PD-L1”. ASH Annual Meeting, Orlando, FL, December 2015 (Oral Presentation).

• Tessa Knox, Maritza Lienlaf, Patricio Perez, Mibel Pabon, Calvin Lee, Fengdong Cheng, Eva Sahakian, John Powers, Susan Deng, Keiran Smalley, Alan Kozikowski, Javier Pinilla, Amod Sarnaik, Ed Seto, Jeffrey Weber, Eduardo M. Sotomayor, Alejandro Villagra. “HDAC6 as master regulator of immune-related pathways”. FASEB SRC 2015. Timmendorf Strand, Germany, August 2015 (Poster presentation).

• Tessa Knox, Maritza Lienlaf, Patricio Perez, Mibel Pabon, Calvin Lee, Fengdong Cheng, Eva Sahakian, John Powers, Susan Deng, Keiran Smalley, Alan Kozikowski, Javier Pinilla, Amod Sarnaik, Ed Seto, Jeffrey Weber, Eduardo M. Sotomayor, Alejandro Villagra. “Histone Deacetylase 6 (HDAC6) as a regulator of PDL-1 expression through STAT3 modulation in melanoma”. AACR Annual Meeting, New Orleans, LA, April 2016. (Poster presentation)


HEMETOLOGY / ONCOLOGY SPONSOR INCOME

Robert Siegel, M.D. BRISTOL-MEYERS SQUIBB COMPANY $12,743.50

Robert Siegel, M.D. JANSSEN RESEARCH & DEVELOPMENT, LLC $7,220.00

Jeanny Aragon-Ching, M.D. ICON CLINICAL RESEARCH INC. $2,412.73

Jeanny Aragon-Ching, M.D. MEDIVATION, INC. $4,037.15

Jeanny Aragon-Ching, M.D. CLINVERSE, INC. $6,708.30

Jeanny Aragon-Ching, M.D. BRISTOL MYERS SQUIBB $2,738.70

Jeanny Aragon-Ching, M.D. LILLY USA, LLC $3,850.00

Imad Tabbara, M.D. CIT BIOPHARMA CORP $3,565.00

Imad Tabbara, M.D. NOVARTIS $165.00

Imad Tabbara, M.D. CELGEN CORPORATION $5,495.00


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HOSPITAL MEDICINEJAMES GEHRING, MDAssistant Professor of Medicine, Interim Division Director

FACULTYShant Ayanian, MD, Assistant Professor of MedicineSuzanne Chang, MD, Assistant Professor of MedicineAlice Chen, MD, Assistant Clinical Professor of MedicineKatherine Goodrich, MD, Associate Clinical Professor of MedicineAnne Lesburg, MD, Assistant Professor of MedicineLinda Lesky, MD, Associate Professor of MedicineNupur Mehta, MD, Assistant Professor of MedicineFarida Izzi, MD, Assistant Professor of MedicineJason Prior, MD, Assistant Professor of MedicineSumugdha Rayamajhi, MD, Assistant Professor of Medicine Juan Reyes, MD, Assistant Professor of MedicineKarolyn Teufel, MD, Assistant Professor of MedicineSara Wikstrom, MD, Assistant Professor of Medicine

VA FACULTYDragica Mrkoci, MD, Assistant Professor of MedicineJesse Theisen-Toupal, MD, Assistant Professor of Medicine

UPCOMING FACULTYNabil Fallouh, MD, Assistant Professor of MedicineCourtney Paul, MD, Assistant Professor of Medicine

Clinically the division continues to see majority of inpatients on a medicine service at the George Washington Hospital. Other clinical responsibilities include committee membership and chairing committees. Linda Lesky co-chairs the Peer Review committee. James Gehring chairs the medical records committee. James Gehring also holds one of the elected seats to the Medical Executive Committee. Clinically, we are taking on new responsibilities this year with taking over the inpatient Internal Medicine consult service. Jason Prior has taken on the remodeling of this service and created new curriculum for the residents and new teaching education for the faculty. The division also includes a midlevel service of 8 PA/NPs.

AWARDSDr. Kate Goodrich, former GW Chief Resident and Director of Hospital Medicine, has been chosen as the Director for the Center for Clinical Standards and Quality (CCSQ).

Dr. Shant Ayanian, Hospital Medicine, was the 2016 Golden Apple Award Recipients.

Dr. Juan Reyes, Hospital Medicine, was selected recipient of the GW SMHS Office of Diversity and Inclusion Retention Initiative conference sponsorship. He was selected for sponsored attendance to the 2016 AAMC Minority Faculty Career Development Seminar in Texas.

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INFECTIOUS DISEASESGARY L. SIMON, MD, PhD, MACPWalter G. Ross Professor of Medicine and of Microbiology, Immunology, and Tropical MedicineDirector of the Division of Infectious DiseasesVice Chairman, Department of Medicine

FACULTYDavid Parenti, MD, Professor of Medicine and Microbiology, Immunology & Tropical Medicine; Director, Traveler’s ClinicAfsoon Roberts, MD, Associate Professor of MedicineMarc Siegel, MD, Associate Professor of MedicineGary Simon, MD, Walter G. Ross Professor of Medicine and of Microbiology & Tropical MedicineCarmelita Tuazon, MD, Professor of MedicineHenry Masur, MD, Clinical Professor of Medicine, NIHMudit Tyagi, PhD, Assistant Research Professor

VA FACULTYDebra Benator, MD, Professor of MedicineCynthia Gibert, MD, Professor of MedicineFred Gordin, MD, Professor of MedicineVirginia Kan, MD, Professor of MedicineAngelike Liappis, MD, Associate Professor of MedicineAmy Weintrob, MD, Associate Professor of Medicine

PAsAimee Desrosiers, PAMaria Zumer, PALinda Salva, PA

CLINICALAbout 50% of patients seen in the outpatient clinic having conditions related to HIV and are being followed for viral control.

TEACHINGThere are 4 ID fellows under the leadership of Dr. Afsoon Roberts. The ID student elective is most heavily populated during the first half of the fourth year.

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RESEARCH• The research portfolio continues to be active and is

growing.• A major portion of the research is the treatment of HIV

and its complications. Much, but not all, is sponsored by pharmaceutical companies. For example, we are now initiating a study in which we will be attempting to measure decreases in cognitive function in HIV-infected elderly patients and compare this with matched, non-HIV infected individuals. This will be coupled with functional MRIs.

• Dr. Siegel has done very well in establishing himself as a leader in HIV prevention research. We have been active participants in the NIH sponsored HIV-prevention trials network in collaboration with SPHHS

• Ongoing proof-of-concept vaccine trial for hookworm. Following this these is the possibility of a phase I trial for a schistosomiasis vaccine as well as a potential for early studies on an HIV vaccine

• Submitted an R21 (Aileen Chang is PI) with MITM for studying Guillain-Barre Syndrome associated with Zika. ID is also involved in a European Union proposal for studying Zika. This is a 10.5 million Euro grant.

CFARDuring the past year The DC Center for AIDS Research (CFAR) was funded by the Nationals Institute of Health. This makes GW one of the 20 such centers in the United States along with some very well-known research institutions such as Harvard, University of Pennsylvania, Johns Hopkins, Duke, University of Washington, UCLA and UCSF. The program in

Washington, DC, is multi-institutional program and includes Georgetown, American University, Howard University, CNMC, the Washington VAMC in addition to GW. The Directors of the DC-CFAR are Dr. Alan Greenberg in SPHHS and Dr. Gary Simon. There are 5 distinct core areas which help to direct funding and research. These are the Administrative core under the direction of Drs. Simon and Greenberg, a basic science core under the direction of Dr. Doug Nixon, Chairman of Microbiology, Immunology and Tropical Medicine; a Developmental Core under the Direction of Dr. Michael Bukrinsky, Professor (MITM); a Clinical and Population Sciences Core under the direction of Dr. Princy Kumar, Professor, Infectious Diseases at Georgetown; and a Social and Behavioral Sciences Core under the direction of Dr. Kim Blankenship, chair of Sociology at American University. Each of the cores has co-directors and administrative support.

The mission of the DC CFAR is to expand our multi-institutional effort to support research that contributes to ending the HIV epidemic in Washington, DC and beyond, in partnership with local government and community.

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In order to successfully accomplish this mission, the DC CFAR is committed to:• Provide scientific leadership and institutional infrastructure

to advance HIV research in Washington, DC• Stimulate and support innovative, interdisciplinary and

translational HIV research• Promote the development and recruitment of early

stage, new and women and minority HIV investigators in Washington, DC

• Advance HIV research in DC by increasing communication and collaboration among HIV investigators in DC with one another and with partners from government, community, other NIH-supported programs and the CFAR network

The DC CFAR also contributes to the national CFAR mission, which is to support a multidisciplinary environment that promotes basic, clinical, epidemiologic, behavioral, and translational research in the prevention, detection, and treatment of HIV infection and AIDS.

The DC-CFAR is led by an executive committee which serves as the governing body for the CFAR and considers all major DC CFAR scientific or structural issues and makes recommendations to the Director and Co-Director. There is an oversight committee which includes senior academic leadership representing each of the six collaborating institutions. This Committee provides central stewardship and institutional support for the DC CFAR. A Scientific Advisory Committee provides strategic, scientific and organizational guidance to the Executive Committee, and is comprised of scientific leaders from other CFARs across the country. There is also a community advisory committee that provides regular

communication between the DC CFAR and community members and organizations. Its goal is to guide CFAR -supported research, ensuring that it reflects the needs of the local HIV/AIDS community.

The DC-CFAR is funded from the NIH and from support from all of the institutions involved in the CFAR. This largest element of support is devoted to the Developmental Core which funds new investigators for pilot research projects in the field of HIV and co-morbidities. Besides the direct funding, being part of a CFAR provides access to supplemental grants that are limited to CFARs. Many CFAR members have been awarded this supplemental funding.

PUBLICATIONS• Hilton S, Castro Nallar E, Pérez-Losada M, Toma I, McCaffrey T, Hoffman E,

Siegel M, Simon G, Johnson W, Crandall K., Metataxonomic and Metagenomic Approaches Versus Culture-Based Techniques For Clinical Pathology., Frontiers in Microbiology, 2016 Apr

• Siegel M, Masur H, Kovacs J., Pneumocystis jirovecii pneumonia in HIV Infection, Seminars in Respiratory and Critical Care Medicine, 2016 Mar

• Siegel M, Borkowska A, Roberts A, Parenti D, Dubrovsky L, Simmens S, Sviridov D, Simon G, Fitzgerald M, Bukrinsky M., HIV infection induces structural and functional changes in High Density Lipoproteins., Atherosclerosis, 2015 Nov

• Swierzbinski M, Pandya S , Zelazny A, Keiser J, Siegel M., Diagnostic Challenges in the Identification of Rothia aeria Bacteremia in a Patient with Relapsing Acute Myeloid Leukemia., Infectious Diseases in Clinical Practice, 2015 Nov

• Petinaux B, Ferguson B, Walker M, Lee YJ, Parenti D, Little G, and Simon GL, A proposed emergency management program for acute care facilities in response to a highly virulent infectious disease, J Emerg Management, 2016 Jan

• Siegel MO, Borkowska AG, Dubrovsky L, Roth M, Welti R, Roberts AD, Parenti DM, Simon G, Sviridov D, Simmens S, Fitzgerald ML, Bukrinsky M, HIV infection induces structural and functional changes in High Density Lipoproteins, Atherosclerosis, 2015 Nov

• Swierzbinski MJ, Kan VL, Parenti DM, Prevalence of Antiretroviral Resistance in Treatment-Naïve Patients, 2007-2010, J AIDS HIV Res, 2015 Jun

• Petinaux B, Ferguson B, Walker M, Lee Y-J, Parenti D, Little G, Simon GL, A proposed emergency management program for acute care facilities in response to Ebola Virus Disease, J. Emerg. Management, 2016

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INFECTIOUS DISEASES

• Sahu G, Farley K, Fassnacht R, Ochem A, Dubrovsky L, Bukrinsky M, Simon G, and Tyagi M, DNA-Dependent protein kinase inhibition potently represses HIV transcription and replication, Journal of Gen. Virology, 2016, In press

• Tyagi M, Weber J, Bukrinsky M and Simon GL, The effects of cocaine on HIV transcription, Journal of Neurovirology, 2016, In press

• Hilton SK, Castro-Nallar E, Perez-Losada M, Toma I, McCaffrey TA, Hoffman EP, Siegel MO, Simon GL, Johnson WE, Crandall KA, Metataxonomics versus metagenomics for clinical pathology, Frontiers in Microbiology, 2016, In press

• Ghafour S, Siegel MO, Simon GL, Immune Reconstitution Inflammatory Syndrome and HIV-Associated Multicentric Castleman’s Disease and Disease and Human Herpes virus-8 Viremia, International Journal of Infectious Disease, 2016, In press

• Turner RS, Chadwick M, Horton W, Simon G, Jiang X, Esposito, An individual with HIV, dementia, and central nervous system amyloid deposition, Alzheimer’s & Dementia: Diagnosis Assessment & Disease Monitoring, 2016, In press

• Simon, GL, Clinical Practice Guidelines for the Management of Candidiasis, Clinical Infectious Disease, 2016, In press

• Siegel MO, Borkowska, AG, Dubrovsky L, Roth M, Welti F, Roberts AD, Parenti DM, Simon GL, Sviridov D, Simmens S, Bukrinsky M, Fitzgerald ML, HIV infection induces structural and functional changes in High Density Lipoproteins, Atherosclerosis, 2015

• Milwalla F, Chen S, Vladisalv T, Simon G, Acupuncture and postpartum pyogenic sacroiliitis: a case report, Journal of Medical Case Reports, 2015

• Siegel MO, Borkowski AG, Dobrosky L, Toth M, Westi R, Roberts AD, Simon GL, Parenti DM, Bukrinski M, HIV infection induces structural and functional changes in HDL., Atherosclerosis, 2015, Nov 2015;243(1)19-29

ABSTRACTS• Lucar J, Hart R, Weintrob A, Siegel M, Parenti D, Benator D, Sexually Transmitted

Infections among HIV Infected Patients Receiving Care in the District of Columbia: Incidence and Correlates of Syphilis, Gonorrhea, Chlamydia and Viral Hepatitis in the DC Cohort. Poster presentation, 52nd , San Diego, CA, October 10th, 2015, IDSA Conference, 2015 Oct

• Aldous AM, Castel AD, Parenti DM, on behalf of the DC Cohort Executive Committee., Prevalence and Trends in Transmitted and Acquired Antiretroviral Drug ResistanceWashington, DC, 1999-2014, ID Week, 2015 Oct

• Lucar J, Hart R, Weintraub A, Siegel M, Parenti DM, Benator D, and the DC Cohort Executive Committee, Sexually transmitted infections among HIV infected patients receiving care in the District of Columbia: Incidence and correlates of syphilis, gonorrhea, Chlamydia and viral hepatitis in the DC Cohort, ID Week, 2015 Oct

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INFECTIOUS DISEASES

INFECTIOUS DISEASES SPONSOR INCOME

Gary Simon, M.D. GLAXOSMITH KLINE, LLC $6,741.50

Gary Simon, M.D. GLAXOSMITH KLINE $7,957.00

Gary Simon, M.D. GLAXOSMITH KLINE LLC $14,472.00

Afsoon Roberts, M.D. GILEAD SCIENCES, INC. $4,952.00



Afsoon Roberts, M.D. GILEAD SCIENCES, INC $16,344.00

Afsoon Roberts, M.D. GILEAD $43,703.00

Afsoon Roberts, M.D. GILEAD $18,906.00

Afsoon Roberts, M.D. GILEAD WITH PPD DEVE AS CRO $5,395.00

David Parenti, M.D. MERCK SHARP & DOHME CORP $1,157.00

David Parenti, M.D. MERCK $7,877.40

David Parenti, M.D. CEPHEID $6,914.00

David Parenti, M.D. MERCK SHARP 7 DOHME CORP $5700


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PODIATRYMICHAEL STEMPEL, DPM, FACFAS Assistant Professor of Medicine and SurgeryDirector, Podiatry Center, Division Director

FACULTYZung Le, DPM, Associate Clinical Professor of MedicineNilufar Medhane, DPM, Clinical Assistant Professor of MedicineFarah Siddiqui, DPM, Clinical Assistant Professor of Medicine

There has been continued growth of the Podiatry Division at GW University Medical Center. With the growth of the Wound Care and Limb Salvage Center, the volume outpatient and inpatient care of diabetic and vascular patients has increased. There has been an increased inpatient and outpatient volume and in the complexity of surgical cases.

The division has continued its educational roll, with several fourth-year student taking the Podiatry and Diabetes elective. Also there are clinical rotations for primary care residents, attending weekly vascular conference, lecturing at Medicine Noon Conference, and participation in education of medical and surgical residents in the hospital setting.

Dr. Stempel submitted a chapter in a volume of Current Problems in Surgery, edited by Dr. Neville, on evaluation care and treatment of diabetic foot complications.

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PULMONARYGUILLERMO GUTIERREZ, MD, PhDProfessor of MedicineDivision Director of Anesthesiology and Engineering and Applied Sciences

FACULTYJalil Ahari, MD, Assistant Professor of MedicineAmandeep Bawa, MD, Assistant Professor of MedicineMorgan Delaney, MD, Associate Professor of Medicine and Pharmacology and PhysiologyVivek Jain, MD, Associate Professor of Medicine; Director, GW Sleep Disorders CenterJeffrey William, MD, Assistant Professor of Medicine

VA FACULTYRobert Maximos, MD, Assistant Professor of MedicineRahul Khosla, MD, Associate Professor of MedicinePrashant Rohatgi, MD, Professor of MedicineSamuel Spagnolo, MD, Professor of Medicine

NPAnne Hunley, NP

UPCOMING FACULTYAnna McLean, MD, Assistant Professor of Medicine 8/1/16

FACULTYThe Pulmonary, Critical Care and Sleep Medicine Division has undergone significant personnel changes during previous two years. In 2014, the unexpected death of a senior faculty member, in addition to the resignation of a second faculty member, reduced the full-time faculty complement in Pulmonary from six to four.

In 2015, Pulmonary recruited two new faculty members (Drs. Bawa and Williams) and another has been recruited for the next fiscal year (Dr. McLean). Also, a nurse practitioner was recruited for the Sleep Disorders Clinic (Anne Hunley), bringing the full complement of the Division to eight members.

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PULMONARY

CLINICAL ACTIVITIESDuring the past few years, the patient population of the Pulmonary, Critical Care and Sleep Division has increased considerably. The Division carries a large clinical load by providing both outpatient and inpatient care. These are:

• Blue Team: Assumed the role of “Pulmonary Hospitalists,” supervising one of the busiest hospital-based housestaff teams. The Blue Team specializes in high acuity of care patients; among the conditions routinely treated are sleep apnea patient on continuous positive airway pressure (CPAP), acute-on-chronic respiratory failure with non-invasive mechanical ventilation (NIV), severe pneumonias, pulmonary emboli, COPD and asthma exacerbations and post ICU patients. The Blue Team census often reaches its maximum allowed number of 20 patients. Faculty rounds 7 days weekly.

• Intensive care unit: Faculty shares rounding in the combined Medico-Surgical ICU and in the Cardio-Thoracic ICU with the Department of Anesthesiology. Faculty rounds 7 days weekly.

• Inpatient consults: Provide hospital wide consultation service in the field of Pulmonary Medicine. Faculty rounds 7 days weekly.

• Bronchoscopies: In addition to bronchoscopies with brochoalveolar lavage and transbronchial parenchymal biopsies, we perform other highly complex bronchoscopic procedures including endobronchial ultrasound transbronchial needle aspiration (EBUS-TBA) for the diagnosis and staging of lung cancer are performed.

• Pulmonary clinics: The outpatient Pulmonary Clinic population has grown large, with waiting time for new

patients approaching three months. There the faculty serves as mentor to students, residents and fellows.

• Sleep Disorders clinics: Very busy clinic serving patients with a variety of sleep disorders.

• Sleep Disorders Laboratories: The Division is in charge of running an eight bed Sleep Laboratory to insuring compliance with all regulations. Our faculty interprets sleep studies, approximately 50 studies per week. The Sleep Laboratory functions 7 days a week, with a waiting time of approximately three weeks.

• Pulmonary Function Tests Laboratory: This is fully equipped laboratory capable of performing pulmonary mechanics, lung volumes and diffusion tests, six minute walk tests, cardio-pulmonary exercise tests, blood gases, oximetry and high altitude oxygen requirements determination with waiting times in the order of 6 weeks.

EDUCATIONAL ACTIVITIES• Pulmonary and Critical Care Medicine fellowship: This is

an ACGME fully accredited and in good-standing program with training for eight fellows under the leadership of Dr. Jalil Ahari. Training takes place at GWU Hospital, the MFA outpatient clinics, the Washington Veterans Administration Hospital and clinics and the Pulmonary Transplant service at INOVA Fairfax Hospital. The three-year fellowship prepares fellows to sit for both the Pulmonary Diseases and the Critical Care AIBM boards. The fellows passing rate has been 100% for the past four years and 92% for the past 15 years.

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• Residents, 3rd and 4th year medical students: The Division’s faculty teaches Internal Medicine residents and medical students during daily didactic rounds in the Blue Team and Consult rounding. Trainees from other Departments, including Surgery and OBGYN are taught in the ICU didactic rounds.

• Medical students: The faculty has significant teaching responsibilities in the new curriculum Cardiovascular, Pulmonary, and Renal Organ Systems (CPR) Block session for 1st year medical student at GW School of Medicine.

EDUCATIONAL ACTIVITIES• Pulmonary and Critical Care Medicine fellowship: This is

an ACGME fully accredited and in good-standing program with training for eight fellows under the leadership of Dr. Jalil Ahari. Training takes place at GWU Hospital, the MFA outpatient clinics, the Washington Veterans Administration Hospital and clinics and the Pulmonary Transplant service at INOVA Fairfax Hospital. The three-year fellowship prepares fellows to sit for both the Pulmonary Diseases and the Critical Care AIBM boards. The fellows passing rate has been 100% for the past four years and 92% for the past 15 years.

• Sleep Fellowship: Along with the Department of Neurology, there is sharing of responsibility for this Fellowship program. Training takes place both at the MFA clinic and the Washington Veterans Hospital. Currently there are three Sleep Medicine fellows. Passing Board rate for the past three years has been 100%.

• Residents, 3rd and 4th year medical students: The Division’s

faculty teaches Internal Medicine residents and medical students during daily didactic rounds in the Blue Team and Consult rounding. Trainees from other Departments, including Surgery and OBGYN are taught in the ICU didactic rounds.

• Medical students: The faculty has significant teaching responsibilities in the new curriculum Cardiovascular, Pulmonary, and Renal Organ Systems (CPR) Block session for 1st year medical student at GW School of Medicine.

CONFERENCES: The Division holds four weekly conferences:• Clinical Case Presentation• Journal Club• Research Conference• Pulmonary CCM Grand Rounds.

PLANSContinue to provide excellent teaching to fellows, residents and medical students.• Review and modify as needed the content and organization

of the First Year Medical School Pulmonary Curriculum.• Provide our Fellows and DOM residents with an electronic

syllabus of pertinent Pulmonary/CCM literature that is updated on a monthly basis.

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RESEARCHThere has been an increase in our research activities resulting in several peer reviewed publications and presentation of abstracts in local and national programs. The thrust of the research has been in the areas of Intensive Care and Sleep medicine. At present the following studies are underway:

• Respiratory variability in obstructive sleep apnea – Application of frequency spectral analysis to data obtained in all night polysomnograms from 204 to 2015. Application of this technique to over 600 studies shows impressive results in distinguishing normal from sleep apnea patients. Abstracts have been presented and two manuscripts are being written.

• Studies on patient ventilator asynchrony in mechanically ventilated patients under way in the GWUH ICU. A large study on the effect of sedatives in these patients has been concluded and another on weaning form mechanical ventilation was started two months ago.

AWARDSDC ACP Chapter 2015 Awardee: Dr. Jalil Ahari, Assistant Professor of Medicine at GW MFA, was awarded the Sol Katz, MD Memorial Teaching Award which honors Excellence in Teaching.

PUBLICATIONS• Rider K, Kaya H, Gutierrez G. Dyspnea associated with silicone breast implant

rupture. Eurasian J. Pulmonology 2015;17 http://www.eurasianjpulmonol.com/jvi.aspx?pdir=eurasianjpulmonol&plng=eng&un=EJP-83803&look4=)

• Kaya H, Rider KE, Amdur RL, Wulf-Gutierrez M, Smith JA, Al Ghamdi A, Maximos RB, Das A, Beyzaei-Arani A, Ballarino G, Türkan H, Bargoty B, Ahari J, Gutierrez G. The effect of race on long term mortality in mechanically ventilated patients.Heart Lung. 2015;19 (http://www.sciencedirect.com/science/article/pii/S0147956315001132).

• D. Kogan D, Jain A, Kimbro S, Gutierrez G, Jain V. Respiratory Inductance Plethysmography Improves Diagnostic Sensitivity And Specificity Of Obstructive Sleep Apnea. Respir Care. 2016 Apr 19. pii: respcare.04436. [Epub ahead of print]

• Gutierrez G. Shining a light on Sepsis. Annals of the American Thoracic Society. Society 2016;13:160-161.

• Jameson H, Bateman R, Byrne P, Dyavanapalli J, Wang X, Jain V, Mendelowitz D. Oxytocin neuron activation prevents hypertension that occurs with chronic intermittent hypoxia/hypercapnia in rats. Am J Physiol Heart Circ Physiol. 2016 Mar 25:ajpheart.00808.2015. doi: 10.1152/ajpheart.00808.2015. [Epub ahead of print]

• Amann VC, Maru NK, Jain V. Hypersomnolence in Wilson Disease. J Clin Sleep Med. 2015 Nov 15;11(11):1341-3.

• Walia R, Achilefu A, Crawford S, Jain V, Wigley SD, McCarthy LH. Are at-homesleep studies performed using portable monitors (PMs) as effective at diagnosing obstructive sleep apnea (OSA) in adults as sleep laboratory-based polysomnography(PSG)? J Okla State Med Assoc. 2014 ;107(12):642-4.

• Dyavanapalli J, Jameson H, Dergacheva O, Jain V, Alhusayyen M, Mendelowitz D. Chronic intermittent hypoxia-hypercapnia blunts heart rate responses and alters neurotransmission to cardiac vagal neurons. J Physiol. 2014 ;592(13):2799-811.

• Gutierrez G. Central and mixed venous O2 saturation: A physiological reappraisal. In: Monitoring Tissue Perfusion: From Physiology to the Bedside. Pinto A and Silva E. (eds) Springer, Dordrecht (Book chapter In Press).

• Jain V, Music Therapy in Sleep Disorders, Music Therapy in the Management of Medical Conditions, Nova Science Publishers, 9781634844925, 2016. (Book chapter In Press).

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PULMONARY

ABSTRACTS• Jose, A. Cramer, K. Davar, A. Bawa, G. Gutierrez, Drug-Induced Lupus Secondary

To Trimethoprim/sulfamethoxazole Presenting With Pleural Effusions And Pericardial Tamponade, ATS 2016, 2016 May, Am J Respir Crit Care Med 2016;193:A1664.

• W. McLean, R. Pirouz, G. Alrehaili, C. Bolinger, K. Rider, H. Kaya, S. Kimbro, R. Amdur, V. Jain, J. Ahari, J. Williams, A. Bawa, Differences In Respiratory Rate Variability Among Patients With And Without Obstructive Sleep Apnea, ATS 2016, 2016 May, Am J Respir Crit Care Med 2016;193:A5977.

• G. Alrehaili1, A. W. McLean, R. Pirouz, C. Bolinger, H. Kaya, K. Rider, S. Kimbro, R. Amdur, V. Jain, J. Ahari, J. Williams, A. Bawa, G. Gutierrez, Respiratory Rate Variability During Normal Sleep, ATS 2016, 2016 May, Am J Respir Crit Care Med 2016;193:A5983.

• R. Pirouz1, A. W. McLean, G. Alrehaili, C. Bolinger, K. Rider, H. Kaya, S. Kimbro, R. Amdur, V. Jain, J. Williams, J. Ahari, A. Bawa, G. Gutierrez, Respiratory Rate Variabiity During Sleep Assessed By Spectral Analysis Of Respiratory Flow, ATS 2016, 2016 May, Am J Respir Crit Care Med 2016;193:A5982

• Bove C, Jain V, Younes N, Hynes M, Diet as a Risk Factor in Obstructive Sleep Apnea, GW Research Day, 2016 Apr

• Bateman R, Kimbro S, Kay M, Jain V, Mendelowitz D, Intranasal Oxytocin administration in patients suffering from Obstructive Sleep Apnea, GW Research Day, 2016 Apr

• Lynn L, Kay D, Younes N, Sen S, Jain V, Accuracy and the Proper Use of the Point-of-Care Analysis in Hemoglobin A1c Measurement, GW Research Day, 2016 Apr

INDUSTRY RESEARCH

PULMONARY SPONSOR INCOME

Morgan Delaney, M.D. GLAXOSMITHKLINE $380.00

Morgan Delaney, M.D. GLAXOSMITHKLINE $214.50

Morgan Delaney, MD SUNOVION PHARMACEUTICALS $350.00

Morgan Delaney, MD SUNOVION PHARMACEUTICALS $416.00


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RENALDOMINIC RAJ, MD, DM, DNB, FASN, FACPProfessor of Medicine and of Epidemiology and Biostatistics and of Biochemistry and Molecular Biology; Division Director

FACULTYScott Cohen, MD, Associate Professor of MedicineAshte Collins, MD, Assistant Professor of MedicineMuralidharan Jagadeesan, MD, Associate Professor of MedicinePedro Jose, MD, Professor of MedicineSusie Lew, MD, Professor of MedicineEhsan Nobhakt, MD, Assistant Professor of MedicineSamir Patel, MD, Associate Professor of MedicineShailendra Sharma, MD, Assistant Professor of MedicineManuel Velasquez, MD, Professor of Medicine

RESEARCH FACULTYInes Armando, PhD, Associate Research ProfessorLaureano Asico, PhD, Assistant Research Professor Prasad Konkalmatt, PhD, Assistant Research ProfessorVan Villar, MD, PhD, Assistant Research ProfessorXiaoxu Zheng, PhD, Assistant Research ProfessorXiaoyan Wang, MD, PhD, Assistant Research ProfessorMaria Wing, PhD, Assistant Research ProfessorAli Ramezani, PhD, Assistant Research Professor

VA FACULTYPing Li, MD, Associate Professor of MedicineCarlos Palant, MD, Professor of Medicine

NPsMarylynn Aminrazavi, NPNancy Uhland, NP

CLINICALThe division continue to expand its clinical activities through active collaboration and innovation. The division has continued to increase the access to outpatient care and the quality of care has also improved through introduction of pre-visit form and outpatient discharge form. We have introduced a number of clinics such as (a) kidney protection clinic; (b) glomerular disease clinic, (c) stone disease clinic and (d) CKD education clinic. We will be establishing the hypertension clinic by July 2016. The inpatient service has expanded as well with the division offering (a) plasmapheresis; (b) leukophersis; (c) slow extended dialysis in addition to continuous renal replacement therapies. We are establishing exchange transfusion at the request of ICU and Heme/Onc. The transplant service is doing well, having performed more than 45 transplants. We have established protocols and policies and procedures and also seamless transition of care from surgery to medicine.

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EDUCATIONThe renal division currently has 6 fellows under the leadership of Dr. Scott Cohen. The division revamped the curriculum and the courses were well received by the medical students. We also get students coming to nephrology rotation and also number of students working with the renal faculty in research as well. The residents rotate through nephrology and has been evaluated as an excellent rotation and a valuable educational experience. The partnership with the VAMC and Inova Fairfax in fellowship training has worked well and it offers a wide spectrum of experience. Nephrology has always filled its fellowship slot each year. Dr. Cohen will assume responsibility as the fellowship director and I am working closely with him to make sure the fellowship training is optimal and continue to attract excellent candidates. The division has offered platform for world renowned clinicians and researcher to speak in “Renal Grand rounds”. We also established “FedMed Conference” in collaboration with the NIH intramural researchers and other universities in DC area, which offers an unique educational experience for the fellows.

Dr. Samir Patel and the Nephrology Division was recognized by the American Society of Nephrology (ASN) as being amongst the top 10 medical schools producing future nephrologists.

RESEARCHThe division welcomed Dr. Jose Pedro, a world renowned researcher and his team. He brought with him number of NIH grants and we are exploring new collaboration and possibly a program project grant in near future. Dr. Jose group has three ongoing projects funded by NIH: (a) Renal Dopamine Receptor: Regulation and Function; (b) Renal vascular oxidative stress in hypertension; and (c) GRK4 and salt sensitivity. They have 3 more R01 grant applications under review. Dr. Raj has about six active federally funded projects and number of new contracts being negotiated. We are in the final stages of completing the Systolic Blood Pressure Intervention Trial (SPRINT). We participate in the Hemodialysis Novel Therapies Consortium with two ongoing projects, ESRD Targut study and Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial (SPin-D Trial). The ACTION study is expected to start by Fall of 2016. We also participate in the CKD Pilot studies consortium with three ongoing studies the Targut CKD study, The CKD Optimal Management With BInders and NicotinamidE (COMBINE)study and Bicarbonate Administration to Stabilize Estimated Glomerular Filtration Rate (eGFR) (BASE) study. The division has done remarkably well in research with more than 40 publications in peer reviewed journals. Fellows contributed to three of the publications. Faculty members have been invited across the world to speak in national and international venues. A number of faculty members serve in editorial boards of highly respected journals, serve as grant reviewers for research agencies across the world including the National Institute of Health.

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AWARDS:DC ACP Chapter 2015 Awardee: Pedro A. Jose, MD, PhD, Professor of Medicine in the Division of Renal Diseases and Hypertension and Professor of Pharmacology and Physiology at GWSMHS, was co-recipient of the prestigious American Heart Associations’ 2015 Excellence Award in Hypertension Research.

Dr. Samir Patel, Renal Division was a featured editor for the January 2016 issue of Advances in Chronic Kidney Disease Journal. He has brought together ten world renowned authors to compile this edition titled “The Elderly and Chronic Kidney Disease.”

Dr. Pedro Jose and Dominic Raj, Division of Renal Diseases and Hypertension, are nominated to the National Heart Lung Blood Institute (NHLBI) Working Group that will critically evaluate the “The Role of Microbiota in Blood Pressure Regulation”.

Dr. Pedro Jose, Professor of Medicine and Physiology, has been named the Chair of the Hypertension and Microcirculation NIH Study Section. This position is awarded to the most highly accomplished researcher.

Ines Armando, PhD, received an award on his recent grant dealing with The Role of Dopamine D2 receptor in Renal Inflammation and Injury from NIH.

PUBLICATIONS• Drs. Anita Nallu, Shailendra Sharma, Muralidharan Jagadeesan, Dominic Raj,

Renal Division, work, “Microbiome in CKD: Challenges and Opportunities”, was accepted for publication in Translational Research Journal.

• HIV-associated immune complex kidney disease Ehsan Nobakht, Scott D. Cohen, Avi Z. Rosenberg , Paul L. Kimmel Nature Reviews Nephrology 12, 291–300 (2016) Published online 19 January 2016

• Ambulatory Blood Pressure in Chronic Kidney Disease: Ready for prime time? Manuel T. Velasquez, Srinivasan Beddhu, Ehsan Nobakht, Mahboob Rahman, Dominic S. Raj. Kidney International Reports, accepted 18 May 2016

• Shokri T, Lew SQ, Sadeghi N: Pedicled parathyroid gland autotransposition in secondary and tertiary hyperparathyroidism. Laryngoscope 2015;125:894-897

• Lew SQ, Nguyen BN, Ing TS: Unusual sites for hemodialysis vascular access construction and catheter placement: A review. Int J Artif Organs 2015;38(6):293-303

• Wing MR, Patel SS, Ramezani A, Raj DS. Gut microbiome in Chronic Kidney Disease. Exp Physiol. 2015 Sep 3. doi: 10.1113/EP085283. [Epub ahead of print] PMID: 26337794.

• Patel SS. The Elderly with CKD: Proceed with Care. Adv Chronic Kidney Dis. 2016 Jan;23(1):6-7.

• Cohen SD, Cukor D, Kimmel PL. Anxiety Disorders in Patients on Hemodialysis. Clin J Am Soc Nephrol, in press

• Cukor D, Cohen LM, Cope EL, Ghahramani N, Hedayati SS, Hynes DM, Shah VO, Tentori F, Unruh M, Bobelu J, Cohen S, et al. Patient and other stakeholder engagement in Patient-Centered Outcomes Research Institute Funded studies of patients with kidney diseases. Clin J Am Soc Nephrol. 2016 May 19 [Epub ahead of print]

• Hedayati SS, Daniel DM, Cohen S, et al. Rationale and design of a trial of sertraline vs cognitive behavioral therapy for end-stage renal disease patients with depression (ASCEND). Contemp Clin Trials 47: 1-11, 2016

• Ramezani A, Devaney JM, Cohen S, Wing MR, Scott R, Knoblach S, Singhal R, Howard L, Kopp JB, Raj DS. Circulating and urinary microRNA profile in focal segmental glomerulosclerosis: a pilot study. Eur J Clin Invest 45: 394-404, 2015

• Nallu A, Sharma S, Ramezani A, Muralidharan, J, Raj D. Gut Microbiome in CKD: Challenges and Opportunities. Translational Research. 2016 Apr 30.doi http://10.1016/j.trsl.2016.04.007

• Aykas F, Solak Y, Erden A, Bulut K, Dogan S, Sarli B, Acmaz G, Afsar B, Siriopol D, Covic A, Sharma S, Johnson RJ and Kanbay M. Persistence of Cardiovascular Risk Factors in Women With Previous Preeclampsia: A Long-term Follow-up Study. Journal of Investigative Medicine. Volume 63, Number 4, April 2015

• Hurtado A, Cancino R, Figueroa J, Padilla E, Morales C, Ortiz I, Sharma S, Johnson RJ, Pando J. Microalbuminuria in Healthy Adolescents: A comparative study at high altitude and at sea level. The Open Urology and Nephrology Journal. ISSN: 1874-303X-Volume 9, 2016

• Kendrick J, Sharma S, Holmen J, Palit S, Nuccio E, Chonchol M. Kidney disease and maternal and fetal outcomes in pregnancy. Am J Kidney Dis. 2015 Jul; 66(1):55-9.

• Sharma S, Nallu A. Associate Editors for the Cochrane Clinical Answers on Interventions for Preventing the Progression of Autosomal Dominant Polycystic Kidney Disease. 2016

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• Fuquay R, Sharma S. Acute Altitude Proteinuria: Insights into Pathophysiology and Public Health Importance. Submitted for review to American Journal of Kidney Diseases in May 2016.

• Sharma S. Gralla J, Gonzalez J, Hurtado ME, Ronchal- Jimenez C, Rivard C, Swenson ER, Schoene RB, Kelly JP, Callacondo D, Sirota J, Fuquay R, Jackson BP, Swenson KE, Johnson RJ, Hurtado A, Escudero E. Acetazolamide and N-acetylcysteine in the treatment of Chronic Mountain Sickness (Monge’s Disease). Submitted for review to Eur Respi Jr on May 2016.

• Kokkinos P, Faselis, Myers J, Sui X, Zhang J, Tsimploulis A, Chawla LS, Palant CE: Exercise Capacity and Chronic Kidney Disease Progression in African-American and Caucasian US Veterans. Mayo Clinic Proceedings. 90(4):461-468, 2015

• Palant CE, Amdur RL, Chawla LS: Acute Kidney Injury and Chronic Kidney Disease: No Respite for a Weary Kidney. Editorial, Am J Kidney Dis. 2015 Oct;66(4):552-4.

• Palant CE, Amdur RL, Chawla LS. The Acute Kidney Injury to Chronic Disease Transition: A Potential Opportunity to Improve Care in Acute Kidney Injury. Contrib Nephrol 187:55-72. doi: 10.1159/000442365. Epub 2016 Feb 8

• Palant CE, Chawla LS, Faselis C, Li P, Pallone TL, Kimmel PL, Amdur RL: High Serum Creatinine Non-linearity: a renal vital sign? In Press. American Journal of Physiology May 18, 2016 : ajprenal.00025.2016

• Chawla LS, Amdur RL, Faselis C, Li P, Kimmel PL, Palant CE. Impact of Acute Kidney Injury on Patients Admitted to the Hospital with Pneumonia. In Review by Critical Care Medicine, February 2016.

• Jose PA, Felder RA, Yang Z, Zeng C, Eisner GM. Gastrorenal axis. Hypertension. 2016 Jun;67(6):1056-63.

• Jose PA. Gastrorenal communication: sniffing and tasting. Exp Physiol. 2016 Apr 1;101(4):457-8

• Villar VA, Cuevas S, Zheng X, Jose PA. Localization and signaling of GPCRs in lipid rafts. Methods Cell Biol. 2016;132:3-23.

• Jose PA, Welch W. Do you want to ditch sodium? Meet nitric oxide synthase 1β at the macula densa. J Am Soc Nephrol. 2016 Feb 22. pii: ASN.2015121378.

• Cai Y, Yang Y, Chen X, He D, Zhang X, Wen X, Hu J, Fu C, Qiu D, Jose PA, Zeng C, Zhou L. Circulating “LncPPARδ” from monocytes as a novel biomarker for coronary artery diseases. Medicine (Baltimore). 2016 Feb;95(6):e2360.

• Gao Z, Han Y, Hu Y, Wu X, Wang Y, Zhang X, Fu J, Zou X, Zhang J, Chen X, Jose PA, Lu X, Zeng C. Targeting HO-1 by epigallocatechin-3-gallate reduces contrast-induced renal injury via anti-oxidative stress and anti-inflammation pathways. PLoS One. 2016 Feb 11;11(2):e0149032.

• Cai Y, Yang Y, Chen X, Wu G, Zhang X, Liu Y, Yu J, Wang X, Fu J, Li C, Jose PA, Zeng C, Zhou L. Circulating ‘lncRNA OTTHUMT00000387022’ from monocytes as a novel biomarker for coronary artery disease. Cardiovasc Res. 2016 Feb 7. pii: cvw022.

• Jose PA, Yang Z, Zeng C, Felder RA. The importance of the gastrorenal axis in the control of body sodium homeostasis. Exp Physiol. 2016 Apr 1;101(4):465-70.

• Liu T, Konkalmatt PR, Yang Y, Jose PA. Gastrin decreases Na+,K+-ATPase activity via a PI 3-kinase- and PKC-dependent pathway in human renal proximal tubule cells. Am J Physiol Endocrinol Metab. 2016 Apr 1;310(7):E565-71.

• Jiang X, Chen W, Liu X, Wang Z, Liu Y, Felder RA, Gildea JJ, Jose PA, Qin C, Yang Z.The synergistic roles of cholecystokinin b and dopamine D5 receptors on the regulation of renal sodium excretion. PLoS One. 2016 Jan 11;11(1):e0146641.

• Wang Z, Zeng C, Villar VA, Chen SY, Konkalmatt P, Wang X, Asico LD, Jones JE, Yang Y, Sanada H, Felder RA, Eisner GM, Weir MR, Armando I, Jose PA. Human GRK4γ142V variant promotes angiotensin 11 type I receptor-mediated hypertension via renal histone deacetylase type 1 inhibition. Hypertension. 2016 Feb;67(2):325-34.

• Richard L Amdur, Harold I Feldman, Jayanta Gupta, Wei Yang, Peter Kanetsky, Michael Shlipak, Mahboob Rahman, James P. Lash, Raymond R Townsend, Ojo Akinlolu, Akshay Roy-Chaudhury, Alan S Go, Marshall Joffe, Jiang He, Vaidyanathapuram S. Balakrishnan, Paul L Kimmel, John W Kusek, Dominic S Raj. and the CRIC Study Investigators* Inflammation and progression of chronic kidney disease: Findings from the CRIC study. Clin JASN (in press)

• Freedman BI, Gadegbeku CA, Bryan RN, Palmer ND, Hicks PJ, Ma L, Rocco MV, Smith C, Xu J, Whitlow CT, Wagner BC, Langefeld CD, Hawfield AT, Bates JT, Lerner , Raj DS, Sadaghiani MS, Toto RD, Wright JT, Bowden DW, Williamson JD, Sink KM, Maldjian JA, Pajewski NM, Divers J. APOL1 renal risk variants associate with reduced cerebral white matter lesion volume and increased gray matter volume. Kidney Int (In press)

• Argyropoulos C, Rondon-Berrios H, Raj DS, Malhotra D, Agaba EI, Rohrscheib M, Khitan Z, Murata GH, Shapiro JI, Tzamaloukas AH. Hypertonicity: Pathophysiologic Concept and Experimental Studies. Cureus 8(5): e596. DOI 10.7759/cureus.596

• Barrows IR, Raj DS. Janus Face of Coronary Artery Disease and Chronic Kidney Disease. J Am Heart Assoc. (In press)

• Fischer MJ, Hsu JY, Lora CM, Ricardo AC, Anderson AH, Bazzano L, Cuevas MM, Hsu C, Kusek JW, Renteria A, Ojo AO, Raj DS, Rosas SE, Pan Q, Yaffe K, Go AS, Lash JP Chronic kidney disease progression and mortality among Hispanics and non-Hispanics. J Am Soc Nephrol (In press)

• Bansal N, Xie D, Tao K, Chen J, Deo R, Horwitz E, Hsu C, Kallem RK, Keane M, Lora CM, Raj DS, Soliman EZ, Strauss L, Wolf M, Go AS. Incident atrial fibrillation and risk of end-stage renal disease: the CRIC study. Clin J Am Soc Nephrol (In press)

• Nassirpour R, Raj DS, Townsend R, Argyropoulos C. MicroRNA biomarkers in clinical renal disease: Diabetic nephropathy and renal transplantation to chronic kidney disease and beyond. Food and Chemical Toxicology (in Press)

• Amdur RL, Mukherjee M, Go A; Barrows IR, Ramezani A, Shoji J, Reilly M; Gerald J,Deo R, Roas S, Keane M, Master S, Teal V, Soliman EZ, Yang P, Feldman H, Kusek JW, Tracy C, Raj DS: Interleukin-6 is a Risk Factor for Atrial Fibrillation in Chronic Kidney Disease: Findings from the CRIC Study, PLos one 1(2): e0148189. doi:10.1371/journal.pone.0148189

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• Ramezani R, Massy ZA, Meijers B, Evenepoel P, Vanholder R, Raj DS. The Role of the Gut Microbiome in Uremia: A Potential Therapeutic Target - A potential therapeutic target. Am J Kidney Dis 2016 Mar;67(3):483-98. doi: 10.1053/j.ajkd.2015.09.027. Epub 2015 Nov 15.

• Jose PA, Raj DS. Gut microbiota in hypertension. Current opin Nephrol Hyper. 2015 Sep;24(5):403-9. doi: 10.1097/MNH.0000000000000149.

• Wright JT, Jr., Williamson JD, Whelton PK, Snyder JK, Sink KM, Rocco MV, Reboussin DM, Rahman M, Oparil S, Lewis CE, Kimmel PL, Johnson KC, Goff DC, Jr., Fine LJ, Cutler JA, Cushman WC, Cheung AK, Ambrosius WT and SPRINT Research Group: A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med 373:2103-2116, 2015

• Poesen R, PhD, Ramezani A, Claes K, Augustijns P, Kuypers D, Barrows IR, Muralidharan J, Evenepoel P,Meijers B, Raj DS. Associations of soluble CD14 and endotoxin with mortality, cardiovascular disease, and progression of kidney disease among patients with chronic kidney disease. C J Am Soc Nephrol. 2015 Sep 4;10(9):1525-33. doi: 10.2215/CJN.03100315. Epub 2015 Jul 7.

• Ramezani A, Dubrovsky L, Pushkarsky T, Sviridov D, Karandish S, Raj DS, Fitzgerald ML, Bukrinsky M. Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection. JPET 2015 Sep;354(3):376-83. doi:

10.1124/jpet.115.224485. Epub 2015 Jun 30 • Chen J, Mohler ER, Xie D, Shlipak M, Townsend RR, Appel LJ, Ojo A, Schreiber

M, Nessel L, Zhang X, Raj DS, Strauss L, Lora CM, Rahman M,Hamm LL, He J.Traditional and Non-traditional Risk Factors for Incident Peripheral Arterial Disease among Patients with Chronic Kidney Disease. Nephol Dial Transplant. 2015 Dec 18. pii: gfv418. [Epub ahead of print]

• Kelly TN, Raj DS, Rahman M, Kretzler M, Kallem RR, Ricardo AC, Rosas SE, Tao K, Xie D, Hamm LL, He J: The role of renin-angiotensin-aldosterone system genes in the progression of chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study. Nephrol Dial Transplant 30(10):1711-1718, 2015

• Isakova T, Ix JH, Sprague SM, Raphael KL, Fried L, Gassman JJ, Raj DS, Cheung AK, Kusek JW, Flessner MF, Wolf M, Block GA. Rationale and approaches to phosphate and FGF23 reduction in CKD. J Am Soc Nephrol 2015 Oct;26(10):2328-39. doi: 10.1681/ASN.2015020117. Epub 2015 May 12.

ABSTRACT• Dr. Vikram Doraiswamy, Nephrology fellow, abstract was selected as the top

research in the category of Clinical Science at the National Foundation 24th Annual Fellows Research Forum.

RENAL SPONSER INCOME

Susie Lew, M.D. ARBOR RESEARCH COLLABORATIVE FOR HEALTH $1,385.00

Manuel Velasquez, M.D. ASTRAZENECA PHARMACEUTICALS LP $3,428.42

Scott Cohen, M.D. INVENTIV HEALTH CLINICAL $1,989.00


INDUSTRY RESEARCH

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RHEUMATOLOGYVICTORIA SHANMUGAM, MDAssociate Professor of Medicine; Division Director

FACULTYRodolfo Curiel, MD, Associate Professor of Medicine; Director, Myositis CenterMandana Hashefi, MD, Assistant Professor of MedicineOlcay Jones, MD, Associate Clinical Professor of Medicine and Anatomy and Regenerative BiologyLisa Rider, MD, Clinical Professor of MedicineNora Taylor, MD, Assistant Professor of MedicinePragya Singh, MD, Assistant Professor of MedicinePatience White, MD, Professor of Medicine and Pediatrics, EmeritusGulnara Mamyrova, MD, PhD, Assistant Research Professor

UPCOMING FACULTYAdey Berhanu, MD, Assistant Professor of Medicine

NPSarah Harris, NP-C

RESEARCH ACCOMPLISHMENTSFY 2016 was a productive year for GW rheumatology in regards research accomplishments. Our faculty successfully renewed three research grants and applied for 3 new grants.

Funded Research Grants: • Cure Juvenile Myositis, Foundation Award $325,200 for

calendar years 2015 and 2016• Genomics and Biomarkers in Chronic Wounds, R013888,

NIH National Institutes of Nursing research, renewed at $390,908 total costs for 2016-17

Funded Clinical Trials: • Abatacept in Dermatomyositis, Bristol-Myers Squibb,

$411,000 for clinical trial to enroll 10 patients with JDM over 2 years.

• Methotrexate plus abatacept vs. methotrexate plus adalimumab in patients with early RA, Bristol-Myers Squibb

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CLINICAL ACCOMPLISHMENTSGW Rheumatology has successfully increased clinical charge and infusion revenues above FY 2014.

In November 2015, clinical operations were moved to the 2300 M Street location and we have been able to improve patient satisfaction and clinic workflows. Our outpatient ultrasound clinic continues to grow and with use of two scanning machines we are able to accommodate all consults for swollen joints within 48 hours. Rheumatology developed several new clinics including the dedicated osteoporosis clinic, a scleroderma clinic and a clinic dedicated to the care of patients with Hidradenitis Suppurativa.

EDUCATIONAL ACCOMPLISHMENTSThe GW Rheumatology team taught GW SMHS students in the MSK block in August 2016, and also provided didactic lectures to the Physician’s Assistant Program in March 2015. Faculty have participated in medical student teaching on the Primary Care Clerkship providing lectures monthly for this group, and several faculty have also had CAP students in their clinics.

Our faculty has been very active in the GW Rheumatology Student Interest Group hosting a career session focused on finding research projects and also a hands on joint injection workshop which was very well received by students. Our team mentored 9 SMHS Medical Students or GW Undergraduates in projects presented at GW Research day. One of our Undergraduate projects won second place in the Research Day Awards.

The GW Rheumatology fellowship remains fully accredited by the ACGME and our team continues to focus on trying to increase the number of fellows we can train. Rheumatology currently has 2 fellows under the leadership of Dr. Rodolfo Curiel. During FY 2017 we intend to also focus efforts on improving Rheumatology education for the GW Internal Medicine Residents. Dr. Nora Taylor has applied for a Clinician Scholar Educator award from the American College of Rheumatology Research and Education Foundation and in the coming months we will work with Dr. Jill Catalanotti to allow more medicine residents to rotate through the Rheumatology Clinic.

On a national level our faculty serve in leadership roles; Dr. Shanmugam serves on the planning committee for the American College of Rheumatology Annual Scientific Meeting and the GW Rheumatology team is actively engaged in educational activities throughout the meeting, serving as poster tour guides, and moderating sessions.

GW Rheumatology also participates in community education – GW hosted the 20th Annual Lupus Summit in March 2016 and our team participates in community events including patient support groups and fundraising activities. GW Rheumatology faculty serve on the medical advisory board for the DC Chapter of the Lupus Foundation and the Arthritis Foundation.

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PUBLICATIONS• Habers GE, Huber AM, Mamyrova G, Targoff IN, O’Hanlon TP, Adams S, Pandey

JP, Boonacker C, van Brussel M, Miller FW, van Royen-Kerkhof A, Rider LG; Childhood Myositis Heterogeneity Study Group. Brief Report: Association of Myositis Autoantibodies, Clinical Features and Environmental exposures at illness onset with disease course in Juvenile Myositis. Arthritis Rheumatol. 2016 Mar;68(3):761-8. doi: 10.1002/art.39466, PMID: 26474155.

• Sismaet HJ, Banerjee A, McNish S, Choi Y, Torralba M, Lucas S, Chan A, Shanmugam VK, Goluch ED, Electrochemical detection of pseudomonas in wound exudate samples from patients with chronic wounds, Wound Repair and Regeneration, 2016 Mar 24, 366-72

• Patel FB, Couch KS, McNish S, Miller JD, Siegel R, Easley S, Shanmugam VK, A 66 year-old woman with hemoptysis, Arthritis Care and Research, 2015 Dec 10

• De Fazio MV, Economides JM, King KS, Han KD, Shanmugam VK, Attinger CE, Evans KK Outcomes after combined radical resection and targeted biologic therapy for the management of recalcitrant Hidradenitis Suppurativa, Annals of Plastic Surgery 2015, Nov 10

• Frech TM, Revelo MP, Ryan JJ, Shah AA, Gordon J, Domsic R, Hant F, Assassi S, Shanmugam VK, Hinchcliff M, Steen V, Khanna D, Bernstein EJ, Cox J, Luem N, Drakos S, Cardiac metabolomics and autopsy in a patient with early diffuse systemic sclerosis presenting with dyspnea: A case report, Journal of Medical Case reports 2015, Jan 136

• Shanmugam VK, Fernandez S, Evans KK, McNish S, Banerjee A, Couch K, Mete M, Shara N, Postoperative wound dehiscence: Predictors and associations, Wound Repair and Regeneration, 2015

ABSTRACTS• Serafi S, Jones O, Mamyrova G, Curiel R, Rider L, Long term outcomes of

patients with Juvenile Dermatomyositis, Presented at Rheumatology Fellows Forum, May 2016

• Tsaltskan V, Serafi S, Curiel R, Rider L, Jones O, Juvenile dermatomyositis with catastrophic gastrointestinal vasculopathy: A case series, Presented at Rheumatology Fellows Forum, May 2016

• Silinsky Krupnikova, SD, McNish S, Croft JD, Collins C, Shanmugam VK, 70 Years of Progress: History of the Rheumatism Society of the District of Columbia, 1946-2016, Presented at Rheumatology Fellows Forum, May 2016

• Brady T, Singh P, Retinal Vasculitis as an initial presentation of Synovitis, Acne, Pustulosis, Hyperostosis/Chronic Recurrent Multifocal Osteomyelitis (SAPHO/CRMO). Presented at GW Research Days, March 2016

• Mamyrova G, Rider LG, Jones O, Ehrlich A, Pachman LM, Nickeson RW, Criscione-Schreiber LG, Miller FW, Jung LK, Curiel RV, Katz JD, Environmental factors associated with disease flare in juvenile and adult dermatomyositis, Presented at GW Research Days, March 2016

• Gross A, Banerjee A, McNish S, Shanmugam VK, Keratinocytes cultured from human chronic wound specimens demonstrate delayed wound closure and differences in apoptosis in in vitro scratch assay, Presented at GW Research Days, March 2016

• Couch KS, McNish S, Banerjee A, Amdur R, Shanmugam VK Opiate exposure is associated with delayed healing in chronic wounds: Preliminary results from the WE-HEAL Study, Presented at SAWC meeting, April 2016

• Mamyrova G, Curiel RV, Wu L, Huber A, Targoff I, Miller FW, Rider LG, Illness onset features and misdiagnosis in juvenile idiopathic inflammatory myopathies (JIIM) differ among clinical and autoantibody subgroups, Presented at First International Conference on Myositis, Stockholm, Sweden, May 2015

• Mangini M, McNish S, Banerjee A, Miller JD, Shanmugam VK, Scleroderma Wounds Exhibit Slower Healing than Wounds from Other Etiologies, Presented at GW Research Days, March 2016

• Mulani S, McNish S, Serafi S, Harris S, Shanmugam VK, Longitudinal outcomes of Hidradenitis Suppurativa patients enrolled in the WE-HEAL Study, Presented at GW Research Days, March 2016

• Akhiyat S, McNish S, Couch KS, Shanmugam VK, Medical Student Competency in Wound Care Guidelines, Presented at GW Research Days, March 2016

RHEUMATOLOGY

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CHIEF MEDICAL RESIDENTS 2015-2016

CHIEF MEDICAL RESIDENTS (left to right)Mortada “Reda” Shams, MD

Jessica Davis, MDAdam Kittai, MD

Courtney Paul, MDErin Vipler, MD

Yevgeniy “Eugene” Vayntrub, MD

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Documents

2015-2016 Annual Report - smhs.gwu.edu · 2015-2016 ANNUAL REPORT ... Cynthia Tracy, MD - Electrophysiology Fellowship ... Aung Myint, DO. VA RESIDENT OF THE YEAR Paul Blair, MD