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1 | Page PROSPECTUS 2013 Centre of Excellence in Molecular Biology 87-West Canal Bank Road, Thokar Niazbaig, University of the Punjab, Lahore, Pakistan, Phone: +92 (42) 5293141-46, Fax: +92 (42) 5293149, Email: [email protected], URL: www.cemb.edu.pk

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    PROSPECTUS 2013

    Centre of Excellence in Molecular Biology

    87-West Canal Bank Road, Thokar Niazbaig, University of the Punjab, Lahore, Pakistan, Phone: +92 (42) 5293141-46, Fax: +92 (42) 5293149,

    Email: [email protected], URL: www.cemb.edu.pk

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    Vice Chancellor’s Message

    University of the Punjab is the prestigious,

    largest and highest seat of learning in Pakistan,

    providing the work force with skilled employees.

    It is playing a distinctive role in furthering the

    nation’s social, cultural, scientific, business and

    economic development. Centre of Excellence in

    Molecular Biology (CEMB) being the part of

    University since 1986 and established itself as

    well renowned hub in the field of molecular

    Biology. The research-focused teaching in the

    Centre ensures our students receive the highest

    quality education which introduces them to the

    frontiers of science and technology provides with

    the skills and discipline to contribute fully to

    whatever career they follow. Our researchers remain committed to the mission of

    conducting basic and applied research that will have significant impact on the health

    and agricultural communities in Pakistan, as well as making significant contributions

    in healthcare worldwide.

    We believe that every student has the requisite potential and our aim is to see that

    this potential is realized and fulfilled. Such a committed, learner-centered approach

    to education means that we have a happy and purposeful community that strives for

    excellence in all academic activities.

    We are all proud of our achievements.

    Prof. Mujahid Kamran

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    Director’s Message

    It gives me immense pleasure to highlight

    the research life and activities during the

    year 2012 at the Centre of Excellence in

    Molecular Biology (CEMB). The dedication

    and hard work of the faculty members and

    the students helped to achieve many new

    findings in different research domains of

    the CEMB like stem cells, plant genomics,

    plant biotechnology, hereditary diseases,

    applied and functional genomics,

    biopharmaceuticals, forensic, molecular

    virology and bioinformatics group.

    The group has discovered the first

    dominant modifier DFNM1, which

    suppresses DFNB26 deafness phenotype.

    Stem cell research scientists in collaboration with LRBT have successfully

    achieved ocular repair in patients by cultured limbal stem cells and amniotic

    membrane with improvement in visual acuity. The seed biotechnology lab

    developed first Pakistani transgenic sugarcane containing four transgenes i.e.

    Glyphosate tolerance gene to control all weeds, SCMV tolerance gene for virus

    tolerance and two Bt genes (Cry1Ac + Cry2A) for borer resistance. Furthermore,

    advanced Bt cotton lines containing CEMB-double Bt genes has also been

    developed and approved by the National Biosafety Committee, Government of

    Pakistan. One of these advanced double gene Bt-cotton lines, CEMB-44 stood

    first in NCBT field trials 2011 conducted by the Pakistan Central Cotton

    Committee (PCCC). There is growing collaboration and partnerships between our

    scientific staff and faculty. They share facilities, equipment, and also scientific

    findings through seminars, colloquia, and lectures. We expect that collaboration

    within and outside CEMB will continue to expand to our mutual benefit in the years

    ahead. Science at CEMB is flourishing not just in terms of publication output but

    also with work that truly breaks new grounds. In the coming years we will try

    everything to make it even better.

    Prof. Tayyab Husnain

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    INTRODUCTION

    Recent break-through discoveries in chemistry, biology and recombinant DNA

    have made molecular biology as the most exciting of sciences and the basis of a

    new technology which will have far-reaching economic implications. To gain a

    firm footing in the new and emerging science, University of the Punjab, Lahore

    established a Centre for Advanced Studies in Molecular Biology for advanced

    teaching and research in the newly emerging science. Later, the Centre was

    upgraded by the Federal Ministry of Education into a National Centre of

    Excellence under the 1974 Act of the Parliament. Recognizing the economic

    potential of the newly emerging science, the Ministry of Science & Technology

    also established a Centre namely Centre for Applied Molecular Biology, physically

    located back-to-back with the National Centre of Excellence in Molecular Biology,

    Lahore. The two Centers have been working in a symbiotic relationship and have

    together addressed the following objectives:

    Teaching and Training: To generate a cadre of specifically trained manpower which can be used to apply the new bioscience to solve specific

    problems of national economic importance.

    International and National meetings: To arrange symposia, seminars in the frontier areas of molecular biological research related to national and

    regional problems.

    Research Activities: To undertake goal-oriented research in agriculture, health, industry and environmental molecular biology.

    Production Activities: To produce critical laboratory materials needed in molecular biological research.

    PREVIOUS PROGRESS:

    Teaching and Training: Produced 327 M.Phil and 119 Ph.Ds with present

    enrollment at 125. The Academy of Sciences for the Developing World (TWAS),

    Trieste, Italy and Asia Pacific International Molecular Biology (A-IMBN), Seoul,

    South Korea has selected CEMB as the regional Centre of Excellence for the

    training of young scientists from Africa/ Asia. At present, five young researchers

    from Bangladesh, Indonesia and Sudan are enrolled for Ph.D. in Molecular

    Biology.

    International and National meetings: The Centre has organized 52 national and

    international symposia/seminars, meetings and specialized training courses. 575

    scientists from Pakistan, and member countries of OIC & SARC (Bangladesh,

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    Egypt, India, Iran, Jordan, Nepal, Sri-Lanka, Turkey) have passed through the

    corridors of the Centre to learn various methodologies and/ or spend sabbatical

    assignments.

    Research Activities: The scientists at the Centre have addressed themselves to

    both basic and applied research.

    The work in basic research, in the field of hearing and vision impairment, has led

    to discovery of 17 new deafness loci, 10 new vision impairment loci, 24 new

    genes and one novel deafness modifier gene. The results of these studies have

    been published in high impact factor, internationally peer reviewed journals with a

    total impact of 517.439.

    Total publication upto 2012 = 350

    Impact Factor upto 2012 = 1011.726

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    RESEARCH PROGRAMMES

    Plant Biotechnology:

    Biotechnology is a tool through which, gene manipulation can be achieved easily

    compared with conventional breeding tools. Cotton (Gossypium hirsutum) is an

    important cash crop of Pakistan. Despite expansion in cultivation area over years,

    increase in productivity per unit area has been very low in Pakistan. Bollworms

    are the major pests of cotton crop. It is estimated that about 20-40% loss occurs

    annually due to different pests of cotton. Currently the pest is controlled by the

    application of pesticide. This control method not only increases the cost of

    production but is also hazardous for the labours applying the pesticide. With the

    advent of Bt technology, it has now become possible to inbuilt borer resistance

    within the cotton plant.

    In Pakistan yield losses due to Cotton leaf curl virus (CLCuV) may go upto 100%.

    Many strategies have been devised to develop resistance in plants against Gemini

    viruses including pathogen derived resistance through the expression of viral

    protein i.e., associated proteins and movement proteins, pathogen derived

    resistance without expression of viral protein i.e., Gene silencing and RNAi and

    resistance due to expression of the non- pathogen derived antiviral agents.

    Despite of all these efforts only moderate resistance has been developed which

    can be easily overcome by the high genetic recombination and mutations of

    geminiviruses.

    Plant Genomics Group

    Cotton an important cash crop and contributes 7.6% value added in agriculture

    and 1.6% to GDP. G.hirsutum (tetraploid) is most widely grown species in

    Pakistan. Abiotic stress, such as drought and high salinity is a major cause of crop

    loss worldwide, reducing average yields more than 50% for major crop plants. G.

    arboreum diploid cotton sp. is the reservoir of biotic and abiotic resistant gene.

    Plant Genomics group is using different techniques like differential display,

    microarray for finding of the new target genes. Differential display is a technique

    which detects the differences in gene expression under specific conditions.

    Microarray is high throughput study for gene expression profiling under particular

    condition.

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    These techniques offer better opportunities to study the structure, function and

    isolation of the biotic and abiotic stress tolerant genes in important plants.

    Seed Biotechnology Group

    Seeds are the delivery systems for agricultural biotechnology. High quality seed

    leads to excellent seedling performance in the field. It is the ultimate goal of

    successful companies to breed crop plants for seed production. Seed quality is a

    complex trait that is determined by interactions between multiple genetic factors

    and environmental conditions. Modern approaches to improve seed quality

    therefore combine classical genetics, plant molecular biology and a variety of

    seed technologies. These "seed biotechnologies" enhance physiological quality,

    vigor and synchrony to establish a crop in the field under diverse environmental

    conditions.

    Scientist in seed biotechnology group are working on the generation and

    improvement of transgenic seed Potato, Sugarcane and hybrid corn. Potato has

    emerged as important cash crop in Pakistan. It is propagated by taking the

    vegetative part of the plant and planting it in soil. Pathogens like viruses that

    establish a systemic infection persist in the vegetative parts of the plant and are

    transmitted generation after generation through the vegetative propagative cycle.

    Therefore, it is necessary to prevent the infection by these pathogens which result

    in severely depressed yields.

    Another important cash crop of Pakistan is sugarcane (Saccharum officinarum).

    Despite expansion in production over years, increase in productivity per unit area

    has been very low in Pakistan. The average sugarcane production in the country

    remained static between 45-50 tons/ha. A number of biotic and abiotic factors are

    limiting yield of sugarcane. Weeds are one of the major problems causing

    reduction in yield. Weeds are of various types and any one weedicide is not able

    to control all.

    Hybrid maize is cultivated in Punjab on about 150,000 ha using almost 4,000 tons

    of seed which is all imported at a very high cost. The current situation calls for

    immediate steps for development and commercialization of local maize hybrids for

    higher yields, better adaptability & genetic diversity. Corn stem borer is one of the

    major pests of maize crop. Currently this pest is controlled by application of

    granulated pesticide in the plant whorl manually which is extremely hazardous for

    the small farmers.

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    Plant Biosafety and Biotechnology Group

    Biosafety evaluation of genetically modified foods is the identification and

    characterization of unexpected changes which may have taken place in the

    organism as a result of the genetic modification process, which could affect the

    safety or nutritional status of the modified organism. Animal experimentation with

    complex foods with the purpose to assess unintended effects has been done to

    access the dietary deficiencies, sensitivity, and small margins of safety. Therefore,

    methods are under development to identify unintended effects through DNA

    sequence and mRNA analysis, analysis of protein expression, or analysis of

    problems of secondary metabolites.

    The Asiatic G. arboreum is resistant to CLCuV, and the group intended to study

    whether the wax plays a critical barrier in transmission of CLCuV by whitefly in

    Asiatic G. arboretum. In 2009, CEMB produced a wax deficient mutant GaMW3

    from Asiatic G. arboreum which has 50% less wax than Asiatic G. arboretum. By

    using this wax mutant plant it has been observed that whiteflies are able to

    transfer virus in wax mutant GaWM3 but not in G.arboreum.

    Cotton is an important fiber crop that is grown throughout the world. It is grown as

    a source of fiber and feed. Lint, the most economically important product from the

    cotton plant, provides a source of high quality fiber for the textile industry. Cotton

    seed is an important source of oil and cotton seed meal is a high protein

    product used as livestock feed. Cotton is the main cash crop of Pakistan which

    contributes significantly to the national economy of the country for being the chief

    source of foreign exchange and for forming the basis of the national textile

    industry. Pakistan has a paramount position as the leading exporter of yarn, the

    third largest exporter of raw cotton and as the fourth largest producer of cotton in

    the whole world.

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    Stem cell Research Group

    The ability of stem cells to differentiate into tissue specific cells and thus repair

    various organs damaged by different diseases, has opened new avenues in the

    field of regenerative medicine.

    The microenvironment in different tissues has profound influence on the

    qualitative and quantitative levels of tissue specific regeneration. The specific

    microenvironment in an organ, differ in healthy, and diseased tissues. A stem cell

    modulates different behavior under the influence of different environment and thus

    exhibit different phenotypic expressions. Thus the study of stem cell

    organogenesis in different microenvironment present in various organs has

    become an important research endeavour. Stem cells may hold the potential to

    form needed cell types in cases where disease or injury has destroyed the original

    cells and can eventually lead to their practical use in the therapy of some of the

    fatal diseases.

    Keeping in mind the importance of stem cells in the regeneration of diseased

    organs the group has selected seven major organs (heart, liver, kidney, pancreas,

    skin, cartilage and eye) to study the regeneration potential of stem cells in various

    disease conditions of these organs mainly in rat/mouse models. The sources of

    stem cells in use are bone marrow, adipose tissues, umbilical cord blood and

    Wharton’s jelly of umbilical cord.

    Applied and Functional Genomics Group

    The research program at applied and functional genomics group is focused on

    hepatitis disease caused by hepatitis C virus (HCV). There are two main goals of

    this group 1) To identify the molecular mechanism of HCV action in the major

    genotypes of Pakistani population and 2) To identify novel therapeutic host targets

    against HCV disease.

    In the previous years, the group has reported in preliminary studies the molecular

    understanding of the mechanisms involved in HCV pathogenesis. The group

    provided leadership in gene expression profiling of human liver tissues containing

    more than 22000 known genes and identified 219 differentially regulated genes

    using microarray. These findings represent a broad portrait of genomic changes

    during early HCV associated fibrosis and cirrhosis. The group has also identified

    small interference RNA (siRNA) targets against HCV genome as therapeutic tool

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    along with host targets. The group has shown that using siRNA against the

    different genotypes of HCV, 70-90% inhibition of viral replication was achieved in

    hepatoma cell lines. Furthermore, the group has generated HCV 3a infectious cell

    culture model system.

    Presently, researchers are focused on viral-host interaction, both in vivo and in

    vitro. The group has expanded preliminary studies to include large population

    samples and also in other diseased samples like cancer to identify genes which

    can help in future to act as prognostic and diagnostic markers. And also to study

    the individual HCV gene interaction with the host machinery during HCV disease

    in hepatoma cell line as well as in infectious 3a cell line that is generated

    previously by the group. These molecular studies seek to define novel interactions

    between HCV genes and cellular targets and address basic mechanisms such as

    viral persistence and antiviral resistance. Researchers in this group has expanded

    their therapeutic target studies to further explore the therapeutic effects of host

    cellular targets and silencing effects of HCV genes in in-vitro models. Gene

    expression profiling has been carried out to understand the molecular mechanism

    behind RNA interference mechanism against HCV and host targets. The overall

    goal of the laboratory is to bridge basic and applied research, in a manner that

    results in the identification of improved therapeutic options for the chronic hepatitis

    C patients.

    Genetic Diseases Research Group

    In Pakistan, there is a high rate of consanguinity which leads to confined and

    multigenerational families. The consanguineous marriage pattern with other

    factors such as religion, ethnicity, language and geography have significant

    implication for increasing the prevalence rate of recessive genetic disorders.

    These extended pedigrees provide a rich genetic source for linkage studies and

    for the identification of genes implicated in many monogenic autosomal recessive

    and X-linked disorders. In this regard, Pakistani population has played a

    prominent role in identifying the novel gene mutations in rare and common genetic

    disorders. The Genetic Diseases Research Group has carried out studies on

    different genetic disorders in Pakistani population such as Hearing impairment

    (HI), Vision impairment and Intellectual disability (ID) / Mental retardation (MR).

    The only approach at present, to reduce the prevalence of genetic disorders is

    prevention. It can be achieved through mandatory carrier screening and genetic

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    counseling in high risk families and continuous educational campaigns for general

    population awareness of genetic disorders. Newborn screening can also help to

    identify genetic disorders early in life so that the treatment can be started as early

    as possible.

    Molecular Virology Group:

    Therefore, the aim of the project is to strengthen research and development

    efforts by improving/adding necessary infrastructure including trained manpower

    to promote the applications of molecular biology, in animal and medical virology

    areas with emphasis on hepatitis and tuberculosis. Efforts are devoted to study

    DNA and RNA viruses of humans and animals prevalent in different geographical

    regions of Pakistan, their life cycles, structure, attachments, entry to host cell,

    uncoating, gene expression, replication, assembly coupled with the development

    of antiviral vaccines. New cost effective and sensitive assays to rapidly detect the

    presence of viruses in variety of specimens of infected persons.

    Any reagents including detection kits, antibodies, cell lines and viral vectors

    successfully developed in the lab will be used for research and commercial

    purposes. Funds generated from these products will be used to support research

    endeavors in the lab and centre.

    Bioinformatics Group

    Bioinformatics Lab of this centre was established in 1998 as Computer Group to

    support the different Labs/Groups of the Centre to access the DNA/Protein

    databases and the repositories of scientific information through the internet. Since

    2005, its role has been expanded to establish as a Bioinformatics resource unit of

    this country.

    Bioinformatics group has a state of the art 5-node HPC Cluster, each node have

    dual Intel Xeon quad core processors, with an FPGA accelerated card in the

    master node. This cluster hold the entire DNA/Protein database available at NCBI

    and have the tools for sequence alignment, database search, literature search

    and EMBOSS applications (more than 250 applications covering the whole range

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    of biological sciences) accessible through JEMBOSS. It also conducts basic

    research, application development and information service in the field of

    bioinformatics. The group consists of eight scientists, working in their area of

    specialty in bioinformatics, has a highly multi-disciplinary profile (molecular

    biology, genetics, statistics, physics, and computer science).

    CEMB Bioinformatics Lab is one of the oldest bioinformatics groups in Pakistan. It

    tries to build a network with which other Pakistani bioinformatics groups from

    universities, medical centers, research institutes and industry can closely

    collaborate. Its three major collaborative programs are research, support and

    training. This group has the honor to sequence and analyze Pakistan human

    genome.

    Biopharmaceutical Group

    Biopharmaceuticals are therapeutic or preventative medicines that are derived

    from living cells, using recombinant DNA technology. Conventional

    pharmaceuticals are generally small molecules, whereas biopharmaceuticals are

    typically proteins, peptides, nucleic acids or inactivated viruses/bacteria. Protein

    drugs are the principal focus of current biotechnology commercialization efforts.

    The aim of CEMB biopharmaceutical research group is to develop indigenous

    technology for the commercial production of recombinant human proteins for

    therapeutic use. The therapeutic impact of cytokines has been felt mainly in the

    field of cancer, blood disorders and infectious diseases like Hepatits B and

    Hepatitis C infections. The group has developed state of the art technology to

    overproduce recombinant human proteins and downstream processing for the

    purification of therapeutic products. Biopharmaceutical group is working on

    recombinant human proteins of cytokines, growth factors and hormones.

    Forensic Research Group

    Forensics Research Lab of this centre was established in 1995 as a separate

    research Group to perform Forensic DNA analysis. Forensic scientists are

    primarily concerned with the improvement and utilization of different types of

    techniques to be utilized in crime investigation. A fast and accurate way for

    paternity and pedigree related cases is DNA testing. But DNA testing depends on

    availability of population databases for statistically accurate results. Therefore,

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    there is a constant need to profile all major populations of Pakistan. Moreover, it

    will help in determining STR (X, Y and autosomal) frequency of different

    populations of Pakistan for the formation of a DNA database which will be useful

    in future forensic casework. Establishment of protocol for accurate DNA profiling

    from highly degraded DNA samples is also in process, especially from highly

    degraded bones. This will help in increased utilization of DNA testing in mass

    disaster victim identification cases.

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    FACILITIES AT CEMB

    DNA sequencing and Primer Synthesis: The institutional DNA core facility is equipped with one ABI-3730, three ABI-3100 and one ABI-310 sequencers. CEMB also offers customized synthesis of DNA primers on ABI-3900 high throughput DNA synthesizer. Insectary:

    The insectary is well equipped with insect rearing facilities. Insect pests, such as American boll worm, spotted boll worm, pink boll worm, rice leaf folder and yellow stem borer are being reared on artificial diet which are used to infest transgenic crop plants. Animal House:

    The animal facility is housed in a separate building comprising of 12 animal rooms, with washing area and feed preparation room. Currently the facility houses different strains of mice and rats. Surgical techniques, pre and post operational care, animal handling procedures are followed according to the Guidelines of Care and use of Laboratory animals prepared by the Centre.

    Library: The Centre houses a moderate-sized library that receives national and international journals and periodicals relevant to Biology. The Centre's library also provides the Internet and electronic Mail facility to communicate with foreign labs and to retrieve the required information from the international data repositories. Bioinformatics/Computer Section: A Local Area Network of computers has been laid down (by the scientists of the Centre) that is also connected to the world wide web through PERN connectivity provided by HEC through PTCL to access the databases and repositories of scientific information, such as GenBank, EMBL, DDBJ, Swiss-Prot, Genome Data Base.

    LINKAGE WITH INTERNATIONAL UNIVERSITY/ORGANIZATION

    S.# Name of the Foreign Institution

    1. John Hopkins University Baltimore, 2. Cold Spring Harber Labs, New York, U.S.A. 3. University of Washington, Seattle, U.S.A. 4. Rockefeller Foundation, US NSF, U.S.A. 5. Department of Biochemistry, Ohio State University 484 W, 12th Avenue,

    Columbus, U.S.A. 6. Department of Entomology, North California State University U.S.A. 7. John Innes Centre, Norwich, Research Park, Colney Lane Norwich,

    NR47UH U.K. 8. National Institute of Bioscience and Human Technology, Tsukuba, Japan. 9. Department of Biochemistry University of Ottawa, Ontario, Canada. 10. International Rice Research Institute, Philippines.

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    11. National Institute of Biotechnology, (GBF) Germany. 12. Plant Genetic Systems, Belgium. 13. Institute of experimental medicine, CNR, ROME, Italy. 14. Institute of Clinical and Biological Research, Microcitemie Hospital,

    University of Cagliari, Sardinia, Italy. 15. Korea Research Institute of BioSciences and BioTechnology, South Korea. 16. Korean Bioinformation Center, South Korea. 17. Personal Genomics Institute, Suwon, South Korea. National Institute of Deafness & other communication disorder, National Institute of health, Laboratory of Molecular genetics 5-Research court, Rockville, MD.

    LINKAGE WITH NATIONAL UNIVERSITY/ORGANIZATION

    Sr. # NAME of the Institution 1. Pakistan Agriculture Research Council. 2. Centre for Applied Molecular Biology, Ministry of Science & Technology. 3. Quaid-e-Azam University Islamabad. 4. Pakistan Atomic Energy Commission Islamabad. 5. Centre for Molecular Genetics, University of Karachi, Karachi. 6. Centre Cotton Research Institute, Multan.

    EXTRA CURRICULUM ACTIVITIES AND REKNOWN ALUMNI

    Following extra curriculum activities are being undertaken in the Centre. 1. The Journal Club of the Centre arranges study/excursion tours to the

    various areas of the Country. 2. The Journal Club also arranges Cricket matches within the members of the

    Centre from time to time. 3. A table tennis court is available in the Centre to play table tennis by the

    members of the Centre. 4. A badminton court is also available in the Centre for playing badminton by

    the members/research scholars of the Centre.

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    DEGREES PROGRAMME AND ADMISSION REQUIREMENTS

    DURATION, SCHEME OF STUDY (SUBJECT ETC) AND NUMBER

    OF SEATS.

    The Centre offer’s M.Phil/Ph.D degree programme in Molecular Biology. ADMISSION REQUIREMENTS: -

    Following are the admission requirements in the M.Phil/Ph.D programme of the Centre. a) Having 1st Class or Minimum CGPA-2.5 in Master Degree and Ist Class or

    minimum CGPA-3.00 in M. Phil in Agriculture, Bio-Chemistry, Bioinformatics, Bio-Technology, Botany, B-Pharmacy, Chemistry, DVM, Environmental Sciences, Medical technology, Microbiology, Microbiology & Molecular genetics, Molecular Biology and Zoology or equivalent qualification.

    b) Desire to pursue future teaching/research career in Molecular Biology and recombinant DNA technology.

    c) Not above the age of 30 year. d) Not more than two 2nd divisions in academic career. Duration:-

    Ph.D. (four to five year) M.Phil (two years) Scheme of Study: - Research plus Theoretical Work. Number of Seats: - Number of seats is not fixed it depends upon ongoing research programmes in the Centre.

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    FEE SCHEDULE FOR M.PHIL 2013-2015

    SR.NO DESCRIPTION 1st

    Semester 2nd

    Semester 3rd

    Semester 4th

    Semester

    1 Admission Fee 300 300 300 300

    2 BenchFee/Tution Fee etc. 14,000 10,850 12,500 10,850

    3 Journal Club 1,050 1,050 1,050 1,050

    4 Examination Fee 3,475 3,475 3,475 3,475

    Total 18,825 15,675 17,325 15,675

    Registration Fee (if applicable) Rs.2,200/= Hostal Dues (if applicable) Rs.4,500/=

    FEE SCHEDULE FOR P.HD 2013-2018

    SR.NO DESCRIPTION 1st

    Semester 2nd

    Semester 3rd,5th,7th,9th

    Semester 4th,6th,8th,10th

    Semester

    1 Admission Fee 300 300 - -

    2 BenchFee/Tution Fee etc. 17,900 14,750 16,400 16,225

    3 Journal Club 1,050 1,050 1,050 1,050

    4 Examination Fee 3,475 3,475 - 14,600

    Total 22,725 19,575 17,450 31,875

    Registration Fee (if applicable) Rs.2,200/= Hostal Dues (if applicable) Rs.4,500/=

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    TEACHING FACULTY

    SR.NO NAME DESIGINATION Qualification

    1. DR. TAYYAB HUSNAIN ACTING DIRECTOR PhD

    2. DR. SHAHEEN N. KHAN PROFESSOR PhD

    3. DR. AHMAD ALI SHAHID ASSISTANT PROFESSOR PhD

    4. DR. IDREES AHMAD NASIR ASSISTANT PROFESSOR PhD

    5. DR. MUHAMMAD IDREES ASSISTANT PROFESSOR PhD

    6. DR. ZIAUR RAHMAN ASSISTANT PROFESSOR PhD

    7. DR.BUSHRA RASHID ASSISTANT PROFESSOR PhD

    8. DR.MOHSIN AHMAD KHAN ASSISTANT PROFESSOR PhD

    9. DR. NADEEM AHMAD ASSISTANT PROFESSOR PhD

    10. DR. ABDUL QAYYUM RAO ASSISTANT PROFESSOR PhD

    11. DR. AZRA MEHMOOD ASSISTANT PROFESSOR PhD

    12. DR. NOREEN LATIEF ASSISTANT PROFESSOR PhD

    13. DR. BUSHRA TABASSUM LECTURER PhD

    14. DR.AFSHAN YASMIN LECTURER PhD

    15. SAMEERA HASSAN LECTURER M.Phil

    16. RASHID BHATTI LECTURER M.Phil

    17. MUHAMMAD SHAFIQUE LECTURER M.Phil

    18. AYESHA LATIF LECTURER M.Phil

    19. SAIRA AZAM LECTURER M.Phil

    20. MARIAM SHAHID LECTURER M.Phil

    21. BUSHRA IJAZ LECTURER M.Phil

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    CENTRE OF EXCELLENCE IN MOLECULAR BIOLOGY

    87-West Canal Bank Road, Thokar Niazbaig, University of the Punjab, Lahore, Pakistan,

    Phone: +92 (42) 5293141-46, Fax: +92 (42) 5293149 Email: [email protected], URL: www.cemb.edu.pk