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@2013 Mehran Mehregany, Ph.D. Mehran Mehregany, Ph.D. Goodrich Professor of Engineering Innova3on Director, Wireless Health Program Director, Case School of Engineering San Diego Programs Wireless Health: Remaking of Medicine by Pervasive Technologies

2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

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Page 1: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Mehran  Mehregany,  Ph.D.  Goodrich  Professor  of  Engineering  Innova3on  

Director,  Wireless  Health  Program  Director,  Case  School  of  Engineering  San  Diego  Programs  

 

Wireless  Health:  Remaking  of  Medicine  by  Pervasive  Technologies  

Page 2: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Enabling  diagnosis,  therapy  and  monitoring  of  health-­‐related  condi;ons  by  tracking  relevant  biomarkers,  managing  treatment  regimen  and  monitoring  progress…while  the  pa;ent  goes  about  his/her  daily  life.    

Wireless  Health  

Febr

uary

201

3 R

elea

se

Page 3: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Digital health is mostly a concept at this time, but a remarkably powerful and rich one that enables effective and efficient ways to collect, forward and process medical data and information within the health care ecosystem.

Digital  Health  

Page 4: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Convergence  of    Pervasive  Technologies  

ubiquitous sensing

wireless connectivity

cloud computing

social networks

Page 5: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Nonintrusive  Monitoring  

The  market  for  wearable  wi

reless  

sensors  is  predicted  to

 grow  to  

400  million  devices  by  2014

.  

Graphic from Don Jones (Qualcomm Life)

Page 6: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Medicine  Will  Change  

clinic/hospital  

appointment  

popula?on  

reac?ve  

anywhere  

any?me  

individualized  

preventa?ve  

Individualized,  preventa?ve  medicine  that  is  ?me  and  place  independent  

Page 7: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Ubiquitous connectivity and computing are bringing about unprecedented mobility…working, entertainment, shopping, socializing, gaming, etc., anytime, anywhere.

This trend is also infiltrating health care, promising significant improvements in quality, convenience, reach and cost of care through “wireless health” solutions.

What  Is  the  Big  Opportunity?  

Page 8: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

How  big  is  it?  

$0$500,000

$1,000,000$1,500,000$2,000,000$2,500,000$3,000,000$3,500,000$4,000,000$4,500,000$5,000,000

1980 1990 2000 2010 2020

Private Medicare Medicaid Out-­‐of-­‐Pocket Other

Mill

ion

($1,

000,

000

is $

1 Tr

illio

n)

Year

Centers for Medicare & Medicaid Services, Office of the Actuary.

National Health Expenditures, $2.6 Trillion in 2010

Page 9: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

NaIonal  Health  Expenditures  

31.4%  

26.6%  

10.0%  

32.0%  

Hospital  care  

Professional  services  

PrescripIon  drugs  

Other  

Other: Nursing facilities & continuing care retirement communities (5.5%), medical devices & hospital supplies (3.2%), home health care (2.7%), government administration (1.7%), net cost of health insurance (5.6%), residential & personal care (5.0%), government public health activities (3.2%), investment (5.7%).

Centers for Medicare & Medicaid Services, Office of the Actuary.

Page 10: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Total  Health  Expenditures,  2008  

GDP Per Capita

Per C

apita

Hea

lth S

pend

ing

“Health Care Spending in the United States and Selected OECD Countries”, April 2011. http://facts.kff.org/chart.aspx?ch=1952

Page 11: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Chronic  Diseases  75%  of  the  Cost    

Disease   #  in  U.S.  

Wireless  Solu?ons  

Alzheimer’s      5    M   Vital  signs,  loca?on,  ac?vity,  balance  Asthma   23    M   RR,  FEV1,  Air  quality,  oximetry,  pollen  count  

Breast  cancer      3    M   Ultrasound  self-­‐exam  COPD   10    M   RR,  FEV1,  air  quality,  oximetry  Depression/  Mood  Disorders  

21    M   Med  compliance,  ac?vity,  communica?on  

Diabetes   24    M   Glucose,  hemoglobin  A1C  Heart  Failure    5      M   Cardiac  pressures,  weight,  BP,  fluid  status  

Hypertension   74    M   Con?nuous  BP,  med  compliance  Obesity   80    M   Smart  scales,  caloric  in/out,  ac?vity  Sleep  Disorders   40    M   Sleep  phases,  quality,  apnea,  vital  signs  

Table from Eric Topol, M.D.

Page 12: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Enhancing  quality    Targeted  care,  at  the  right  ;me,  based  on  collec;on  and/or  communica;on  of  relevant  health  data  and  informa;on.    New  care  possibili;es  that  are  enabled  through  con;nuous  monitoring,  wireless  communica;on  and/or  rich  new  databases  of  disease  condi;ons.      

Improving  convenience    By  the  mobility  afforded  the  pa;ents  and  the  care  providers.      

Extending  reach    Possibili;es  in  diagnosis,  therapy  and  monitoring  at  a  distance  and/or  in  places  otherwise  difficult  to  reach.      

Reducing  cost    Keeping  pa;ents  out  of  care  facili;es  through  preventa;ve  care  solu;ons  and  ;mely  diagnosis.    Reducing  errors  and  amplifying  the  produc;vity  of  the  health  care  providers.    

Wireless  Health  Value  ProposiIon  

Page 13: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Diabetes  

Page 14: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Heart  Rate  Fluid  Status  Ac;vity  Level  Posture  Respiratory  Rate  Arrhythmia  Detec;on  Temperature  ECG  

Heart  Failure  

Page 15: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Energy  Intake  and  Expenditure  

Page 16: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Sleep  Quality  

Page 17: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Zeo  Sleep  Data  

Page 18: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Fetal  Monitoring:  Sense4Baby  

Page 19: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Measurement  Provisioning  

Unobtrusive  -­‐  Measurement  devices  must  be  small  

 Power  and  data  rate  

-­‐   Ultra  low  power  for  ba[ery  to  last  -­‐   High  rate  for  real-­‐;ne,  data-­‐intensive    applica;ons  

 Security  

-­‐  Data  must  remain  private    Smart  nodes  

-­‐  IP  transport  and  protocols  from  sensor  to  servers    Flexible  deployment  topologies  

-­‐  Star  or  mesh  -­‐  Scalability  

Page 20: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Compliance  

Page 21: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Seamless  Data  Transfer    ConnecIn

g  medica

l  device  data  to  paI

ents  

and  clinicia

ns  wire

lessly.  

Page 22: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

In-­‐PaIent  Data  Directly  to  the  Doc  

Page 23: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

ECG-­‐in-­‐the-­‐Pocket  

Page 24: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Technology  availability    The  extent  and  richness  of  solu;ons  possible  to  a  wide  range  of  health  problems.      

Acquisi;on  and  ownership  cost    Costs  associated  with  purchasing  the  solu;ons  and  opera;ng/maintaining  them,  respec;vely.      

Regulatory  efficiency    The  ;me  and  cost  associated  with  obtaining  approval  for  specific  solu;ons  to  par;cular  health  problems.      

Reimbursement  policy    Covering  the  cost  of  u;lizing  wireless  health  solu;ons,  including  when  used  for  preven;on,  which  is  a  great  applica;on  opportunity  for  wireless  health  but  not  reimbursable  for  the  most  part  today.  

Obstacles  

Page 25: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Clinical  and  health  educa;on    The  need  for  the  health  providers  to  adopt  wireless  health  solu;ons  and  know  when/how  to  deploy  them.    Teaching  pa;ents  about  preventa;ve  and  self-­‐management  prac;ces.      

Demonstrated  outcomes    Clinical  or  field  studies  that  show  the  efficacy  of  wireless  health  solu;ons.      

Pa;ent  awareness    Visibility  of  pa;ents  into  wireless  health  solu;ons  in  order  to  promote  their  own  interests.    

Interstate  medical  prac;ce  Ability  to  prac;ce  medicine  across  state  lines.        

Obstacles  

Page 26: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Wireless  Health  Graduate  EducaIon  

Master  of  Science  &  Graduate  Cer;ficate  §  Electrical  or  Biomedical  Engineering  §  Apply  now  for  Fall  2014  

Se`ng  the  standard  for  wireless  health  educa;on  §  First  ever  curriculum  designed  specifically  for  wireless  

health  and  comprised  of  en;rely  new  courses  tuned  accordingly  

Onsite  in  San  Diego  because  of  the  city’s  wireless  health  leadership.    Available  worldwide  online.  

Connected  to  the  main  campus  in  Cleveland    

Page 27: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Wireless  Health  Curriculum  

Page 28: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Ubiquitous connectivity and computing are bringing about unprecedented mobility…working, entertainment, shopping, socializing, gaming, etc., anytime, anywhere.

This trend is also infiltrating health care, promising significant improvements in quality, convenience, reach and cost of care through “wireless health” solutions.

What  Is  the  Big  Opportunity?  

Page 29: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Health care is a critical global issue, for example

Obesity: 400,000,000

Chronic disease: 860,000,000

Aging: 600,000,000

Compliance: $300,000,000,000

How  Big  Is  It?  

PE

OP

LE

Page 30: 2013 MEPTEC MEMS Technology Symposium - Mehreganymeptec.org/Resources/03 - Case Western.pdf · Hospital’care’ Professional’services PrescripIon’drugs Other Other: Nursing

@2013 Mehran Mehregany, Ph.D.

Thank  You!  

Mehran Mehregany, Ph.D. Director, Wireless Health Program

Director, Case School of Engineering San Diego Programs 216-368-0755 (tel) [email protected] (e-mail) http://engineering.case.edu/wireless_health

Our  Wireless  Health  Program  is    San  Diego  Based,  Cleveland  Connected