2009 Pandemic H1N1 Influenza Epidemiology

April 2009 – January 2010Preliminary

Laboratory-confirmed (Culture & Rapid Tests) Influenza Cases & Influenza-Like Illness, Massachusetts 2008-2009

0

250

500

750

1000

1250

1500

1750

2000

2250

2500

2750

3000

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 35 37

MMWR Reporting Week

La

bo

rato

ry-C

on

firm

ed In

flu

enza

Cas

es1

0.00%

1.00%

2.00%

3.00%

4.00%

5.00%

Per

cen

t In

flu

enza

-Lik

e Ill

ne

ss2

Culture Reports

Rapid Reports

Percent Patients With ILI

1. Influenza cases confirmed via viral culture or rapid test by specimen collection date.2. Influenza-like illness (ILI, defined as fever>100F and cough and/or sore throat), as reported by Massachusetts sentinel surveillance sites by CDC week date.

Source: Massachusetts Immunization Program

Laboratory-Confirmed Influenza Cases and Influenza-Like Illness

Massachusetts, October 4, 2009 – January 21, 2010

0

200

400

600

800

1000

1200

1400

1600

1800

2000

2200

2400

2600

2800

3000

3200

3400

3600

3800

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 35 37 39

MMWR Reporting Week

Lab

ora

tory

-Co

nfi

rmed

In

flu

enza

Cas

es*

0

1

2

3

4

5

6

7

8

9

10

11

12

Per

cen

t In

flu

enza

-lik

e Il

lnes

s**

Source: Massachusetts Immunization Program BID Office of Surveillance and Informatics Services

Percentage of Influenza-Like Illness Visits Reported by Sentinel Provider Sites - Massachusetts

Source: Massachusetts Immunization Program

0

1

2

3

4

5

6

7

8

9

10

40 42 44 46 48 50 52 1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 35 37 39

MMWR Reporting Week

% I

nfl

ue

nza

-Lik

e I

lln

es

s*

2009-2010 2008-2009 2007-2008

novel 2009-H1N1 DUB – 30 DEC 2009 Data are provisional and will not be officially released by the CDC until 1100 EDT

Internal Use Only (FIUO)---For Official Use Only (FOUO) -Sensitive But Unclassified (SBU) - NOT FOR FURTHER DISTRIBUTION

Epidemiology/SurveillanceILINet Cumulative Number of Standard Deviations Above Non Influenza Season Mean – H1N1Both Waves

April 26 – December 13, 2009

0

50

100

150

200

250

300

350

Cu

mu

lativ

e S

D o

ver

bas

elin

e

ILI Net Number of SD Over Baseline All Waves

Source: Massachusetts Immunization Program

N = 389

Source: Massachusetts Immunization Program

Source: Massachusetts Immunization Program

Source: Massachusetts Immunization ProgramMDPH MassCHIP 2005 Population Estimates

N = 389

Source: Massachusetts Immunization Program

N = 389

Source: Massachusetts Immunization ProgramMDPH MassCHIP 2005 Population Estimates

N = 1959

Source: Massachusetts Immunization ProgramMDPH MassCHIP 2005 Population Estimates

N = 389

Source: Massachusetts Immunization ProgramMDPH MassCHIP 2005 Population EstimatesDeath proportions based on 2007 data – MDPH Registry of Vital Statistics

N = 30

Source: Massachusetts Immunization ProgramMDPH MassCHIP 2005 Population Estimates

Source: Massachusetts Immunization ProgramMDPH MassCHIP 2005 Population Estimates

Source: Massachusetts Immunization ProgramMDPH MassCHIP 2005 Population EstimatesDeath proportions based on 2007 data – MDPH Registry of Vital Statistics

Source: Massachusetts Immunization ProgramMDPH MassCHIP 2005 Population Estimates

Source: Massachusetts Immunization Program

novel 2009-H1N1 DUB – 30 DEC 2009 Data are provisional and will not be officially released by the CDC until 1100 EDT

Internal Use Only (FIUO)---For Official Use Only (FOUO) -Sensitive But Unclassified (SBU) - NOT FOR FURTHER DISTRIBUTION

Epidemiology/SurveillanceProportion of Adults Immune from Natural Infection and Proportion with Natural and Vaccine

Induced Immunity by State December 13, 2009

0

10

20

30

40

50

60

70

80

Cu

mu

lati

ve

% im

mu

ne

Verm

on

t

Delaw

are

Illino

is M

aine

Alaska

District

So

uth

Da

Wis

consi

So

uth

Ca

Co

nnect...

Min

neso

ta

Rh

ode Is

Florida

Arizon

a

Pu

erto R

ico

Wa

shing

t

New

Yo

rk

Miss

ouri

Alab

ama

No

rth Da

Mass

achu

Iow

a N

ew H

amp

Ohio

N

YC

Nevad

a

Indiana

Kan

sas

Califo

rn

Marylan

d

Mich

igan

Pen

nsylv

Georgia

Oklah

oma

Mo

ntan

a

Oreg

on

Wy

omin

g

We

st Vir

Neb

raska

Texas

Idah

o

Ten

nesse

No

rth Ca

Miss

issi

Haw

aii

Virgin

ia

Lou

isian

Co

lorado

Arkan

sas

New

Mexi

New

Jers

Ken

tucky

Utah

Estimated Proportion Immune Natural Immune plus Vax

novel 2009-H1N1 DUB – 30 DEC 2009 Data are provisional and will not be officially released by the CDC until 1100 EDT

Internal Use Only (FIUO)---For Official Use Only (FOUO) -Sensitive But Unclassified (SBU) - NOT FOR FURTHER DISTRIBUTION

Epidemiology/SurveillanceProportion of Adult Population Immune by Natural Infection and Vaccination