2004 Lennox - Medical Applications of Accelerators

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    Medical Applications

    of Accelerators

    AJ Lennox Sacramento AAPT/APS 2004

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    Medical Applications of

    Accelerators

    Basic Types of Accelerators

    _ Linear: High voltage or radiofrequency

    _ Circular:

    Cyclotron or Betatron Synchrotron

    Common Medical Applications

    Photon/Electron Radiation Therapy

    Isotope Production

    Equipment Sterilization

    Hadron Therapy

    Future Applications

    Angiography

    Boron Neutron Capture Therapy

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    Linear Accelerators

    Cockroft-Walton - first high voltage accelerator

    Scharf, Particle Accelerators and their Uses, p 17.

    Also: Van de Graaff, Tandem Cascade, Dynamitron

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    Linear Accelerators

    Radiofrequency (rf) Ion Linac

    Drift Tubes

    Livingood, Cyclic Particle Accelerators, p 7.

    Also: rf electron linacs

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    Schematic of Basic Cyclotron

    Livingood, Cyclic Particle Accelerators, p111

    Circular Accelerators

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    Argonne Cyclotron Showing Deuteron Beam

    Livingood, Cyclic Particle Accelerators, p 129

    Circular Accelerators

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    Schematic of Basic Betatron

    Scharf, Particle Accelerators and their Uses, p 23.

    Circular Accelerators

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    Schematic of Basic Synchrotron

    Kernan, Particle Accelerators, 1968.

    Circular Accelerators

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    Photon/Electron Therapy

    Schematic Varian Clinac 1800 linear accelerator

    Karzmark et al, Medical Electron Accelerators, p12.

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    Photon/Electron Therapy

    Gantry rotates

    around patient.

    Linear accelerators

    are manufactured byseveral vendors.

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    11 MeV proton cyclotron for short-lived isotopes

    Univ of Wisconsin,

    1999Also 70-MeV cyclotrons for long-lived isotopes

    Isotope Production

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    Isotope Production

    7 MeV proton linac for short-lived isotopes

    AccSys Technology, 1999

    Also: 70-100 MeV linacs for long-lived isotopes

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    Equipment Sterilization

    10-MeV Moelnlycke electron linacs

    Scharf, Biomedical Particle Accelerators, p 577.

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    Proton Therapy Synchrotron under construction at Fermilab

    Hadron Therapy

    Also C clotrons

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    Heavy Ion Synchrotrons at Chiba (Tokyo)

    HIMAC

    Science, 261(1270), 1993

    Hadron Therapy

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    Superconducting Cyclotron on Gantry for Neutron Therapy

    Maughan and Yudelev, Harper Hospital, Detroit

    Hadron Therapy

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    protonsBe target

    Fast Neutron Therapy Cyclotron - Seattle

    Maughan and Yudelev

    Hadron Therapy

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    Hadron Therapy

    Proton Linac for Neutron Therapy - Fermilab

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    p(66)Be(49) produces neutrons

    Hadron Therapy

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    Angiography

    2 GeV electron synchrotron -Daresbury, UK

    Scharf, Biomedical Particle Accelerators, p 475.

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    Boron-Neutron Capture Therapy

    2.5 MeV Electrostatic Quadrupole HV accelerator (Berkeley)

    Ludewigt et al, Albuquerque, 1997, p 489.

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    References

    American Nuclear Society, Proceedings of Topical Meeting on

    Nuclear Applications of Accelerator Technology, Albuquerque

    NM, Nov 16-20, American Nuclear Society,1997.

    Karzmark,CJ, et al, Medical Electron Accelerators, McGraw-Hill,NY, 1993.

    Kernan, WJ,Accelerators, US Atomic Energy Commission, Oak

    Ridge, TN, 1968.

    Livingood, Cyclic Particle Accelerators, Van Nostrand, NJ,

    1961.

    Scharf, W, Particle Accelerators and Their Uses, HarwoodAcademic Publishers, UK 1986.

    Scharf, W, Biomedical Particle Accelerators, American Institute

    of Physics, New York, 1994.