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LSM1104General Physiology

2012-13

Semester 2Prof Alex Y. K. Ip

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Professor Alex Y K Ip

(Molecular and EnvironmentalPhysiology)

Department of Biological SciencesBlk S1A

ROOM: 05 15A

TEL: 6516-2702Email: dbsipyk@nus.edu.sg

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Connect between thermodynamics,

bioenergetics and various physiological

processes, especially those at the cellular

level. Deal with the transformation of energy in

cellular processes, focusing on the plasma

membrane, muscle and neurons.

Evaluate the production and dissipation of

heat in animals.

Organization Objectives

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Know the basic physiological processes

occurring in animals

Understand how these basic physiological

processes are integrated in animals to enable

them to live in a variety of environment.

Learning Outcome Objectives

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Workload for Prof Ips section

16 hours lectures + 18 hours (6 practicals, 3

hours each) practicals

40% CA (20% test Prof Kumar + 20% test Prof

Ip)

60% Final exam

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Topics

1. Introduction

2.Energy and thermodynamics

3.Feeding and digestion

4. Ionic gradient, electrical potential

5.Electrical signals and neurons

6.Cytoskeletons, motor proteins and muscle

7.Heat production and body temperature

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Reading assignment

There are reading assignments for every topic,

Q&A being the most important.

You should also read the articles and visit the

websites. You will score better in the exam if

you go through them.

Please go through the reading assignments

before the lecture, and read through the

relevant Q&A after the lecture.

You are not required to submit lab reports but

information covered can be tested in the CA

and/or the final exam.

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1. Reading assignments

2. Monitor your own learning

3. Weekly Q&A

4. Mind map

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How to do well in Prof Ips section

of LSM1104?

1. Dont sleep during class.

2. Take concise notes.

3. Dont just memorize but try to understand.

4. Ask questions during class.

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Important Dates

April 8 (6pm) test (CA2)

May 6 (9am)- Exam

There is only one supplementary test, and

usually the supplementary test may have a

format different from and can be more difficult

than the original one. So, please make everyeffort to attend the first test if possible.

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1968, Ying Wah College,

HK

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1975, University of Minnesota, MLPS, USA

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Department of Zoology (1982)

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NUS as the home of the

mind where students

develop intelligentbehaviors and have

significant contribution

to the society in the

future

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Receptive mode

Vs

Search mode

Spoonfeeding

Regurgitation

MemorizingCopying

Thinking

ReflectingAnalyzing

evaluating

Synthesizing

Questioning

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Wonderment, Inquisitiveness,

Curiosity

All thinking begins with wonderment

---Socrates---

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Questioning and Problem Posing

What did I learn today?What good questiondid I ask today?

Creativity is a function of questions

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Understanding . . . grows

from questioning oneselforfrom being questioned by

others, such as teachers.

Sizer, T. Horace's Compromise: The Dilemma of

the American High School. 1984. Boston.

Houghton Mifflin. page 117.

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Learning is not passive listening

To understand the topicTo reformulate material

To use it

To analyse it, filterif necessary

To re-structure it, build connections

To question it, doubtTo search and weigh evidence

To rejectthose parts of it that dont stand scrutiny

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Collect information

Integrate/connect information

Organize/connect information

Select/filter information

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Learning = new information + new

skills + new experience

Learning =making new connections

between information, skills andexperience

Learning = un-learn + re-learn

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Each student must be attracted to some

extent by two or more competing

hypotheses and feel temporarily unableto make a choice between them,

otherwise, for him, no problem exists.

The importance of controversy:

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If teachers are to teach reflectively, they

must help students expose contradictions

and inadequacies in theirown thinking

and action to theirown critical

examination.

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Forked path: Critical thinking skills

and strategies

GOAL

GOAL

?

?

??

?

?

GOAL

GOAL

GOAL

GOAL

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In a global information environment,

the old pattern of education in answer-finding is one of no avail: one is

surrounded by answers, millions of

them, moving and mutating at electricspeed. Survival and control will

depend on the ability to probe and to

question in the proper way and place.

M. McLuhan (probably written 30 or 40 years ago)

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The role of questions in teaching,

thinking and learning:

http://www.criticalthinking.org/articles/thinking-some-purpose.cfm

http://www.criticalthinking.org/articles/thinking-some-purpose.cfmhttp://www.criticalthinking.org/articles/thinking-some-purpose.cfmhttp://www.criticalthinking.org/articles/thinking-some-purpose.cfmhttp://www.criticalthinking.org/articles/thinking-some-purpose.cfmhttp://www.criticalthinking.org/articles/thinking-some-purpose.cfmhttp://www.criticalthinking.org/articles/thinking-some-purpose.cfm

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http://mayoresearch.mayo.edu/mayo/research/staff/peng_k.cfm

Peng Kah Whye

http://mayoresearch.mayo.edu/mayo/research/staff/peng_k.cfmhttp://mayoresearch.mayo.edu/mayo/research/staff/peng_k.cfm

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1988-freshman; work part-time as an RA

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Scientist specialize

in cancer research

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Cambridge 1993-1996 Ph.D.working

on gene therapy for cancer patients

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Cancer research

aiming for clinical trial

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Dr Peng Kah Whye

Professor at Mayo Clinic

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I guess, at the end of the day, all the glamour and

publicity are meaningless. They are nice for a while

for the ego. The Nature paper few people will notice.

But what drives me and keeps me going is my belief

that I want to do good and make tomorrows worldbetter than todays, for the next generation. To relief

pain and suffering and offer hope to the cancer

patients. So often, I want to hold their hands and

channel my best wishes to them, for being brave togo on phase I clinical trials in which they know is not

likely going to benefit them, but perhaps, the next

generation.

Dr Peng said (2005):

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End