198 Date : 20-May-2018 Feedback · Date : 20-May-2018 Feedback Page 1 for Lipid Investigations Distribution : 198 Laboratory : Birmingham Quality is part of the University Hospitals

Date : 20-May-2018

Feedback

Page 1

for Lipid Investigations

Distribution : 198

Laboratory :

Birmingham Quality is part of the University Hospitals Birmingham NHS Foundation Trust and provides this UK NEQAS service from PO Box 3909, Birmingham B15 2UE, UK To contact us, email [email protected] or phone us on +44 (0)121 414 7300

© Data in UK NEQAS / Birmingham Quality reports is confidential. For this Scheme, the Organiser is Jane French Birmingham Quality is a UKAS accredited proficiency testing provider No. 7860. www.birminghamquality.org.uk

Published at 9:19 on Thursday 7 June 2018

Quality ManagerPathology LaboratoryBiochemistry DepartmentTownCountyPostcode

This Scheme is essentially web-based. We can alert you to information regarding the Scheme via email. The e-mail address (or addresses) we are currently using to contact your laboratory is shown below in red . If no e-mail address is displayed or the information shown is incorrect, please email us with an appropriate contact e-mail address as soon as possible, using the word 'feedback' in the title line. Based on the date information you have provided, the transit time from specimen dispatch [ ] to receipt [ ] was day(s), and the subsequent time to analysis [ ] in your laboratory was day(s). (Missing values indicate dates not provided. "0 days" represents same day). Any comments you made to us are shown below and have been acted upon where necessary Any specific comments applicable only to laboratory are shown below Any general comments applicable to all laboratories are shown below Report authorised on Friday 25 May 2018 by: Jane French Programme Director, UK NEQAS for Lipid Investigations

Birmingham Quality is a UKAS accredited proficiency testing provider No. 7860. Please see http://www.ukas.com for full details of the accreditation status of our services

Birmingham Quality is proud to offer EQA services that adhere to the Code of Practice and have the badge of quality of UK NEQAS

of 22

Date : 20-May-2018

Performance Summary Icons (click graph for details)

Page 2


Distribution : 198

Laboratory :




B s

core

C score

Total cholesterol

P-ABCPENR (DASH1)

0 5 10

-10

-5

0

5

10

B s

core

C score

Triglyceride

P-ABCPENR (DASH1)

0 5 10

-10

-5

0

5

10

B s

core

C score

HDL cholesterol

P-ABCPENR (DASH1)

0 5 10 15

-15

-10

-5

0

5

10

15

B s

core

C score

non-HDL cholesterol

P-ABCPENR (DASH1)

0 5 10 15

-15

-10

-5

0

5

10

15

B s

core

C score

LDL cholesterol

P-ABCPENR (DASH1)

0 5 10 15

-15

-10

-5

0

5

10

15

of 22

Date : 20-May-2018

Participation summary

Page 3


Distribution : 198

Laboratory :




All our time periods are 'rolling' to give you current information. You may wish to keep you own log of Calendar Year or Financial Year time points if you require 'year-end' statements for your own internal use. Any analytes with out of consensus performance will be highlighted in red and can be clicked for further details.

TriglycerideHDL cholesterol

You have no performance data for:

You have out of consensus performance for:

LDL cholesterolYou have in consensus performance for:

non-HDL cholesterol

Total cholesterol None

Analytical Performance over the last 6 months (rolling time window of 6 distributions)

This scheme cycle is notionally every four weeks. Analytically, we assess you over a six month time window (6 Distributions). For return rates, late and amended results we assess you over a twelve month period (12 distributions).

SatisfactorySatisfactorySatisfactory

0 distributions from the last 12Participation

0 distributions accepted from the last 12AmendmentsLate Returns

12 distributions out of a possible 12

Participation and Return Rates

Distributions Affected Distributions Rating

You can judge, in association with your IQC and other QA measures, if your current performance is a blip or part of a trend.

You have no specimen %bias etc. for:

HDL cholesterolTriglyceride

Homocysteine

In consensus for all specimens for:Out of consensus for at least one specimen for:

Apo B

non-HDL cholesterolApo A1Lp(a)

VLDL cholesterol

LDL cholesterol

You are not registered for:

Total cholesterol None

Analytical Performance for specimens from distribution 198 only

of 22

Date : 20-May-2018

Distribution Summary

Page 4


Distribution : 198

Laboratory :




%biasBResult A score C scorePool CB scoreTargetSpecimen ASpecimen

2.9-0.1

4.7

1.37

5.2

(mmol/L)

2.56

-1.6

3.10

198A

198C

-0.8

198A

6.9

1.07

+1.4

580

2.64

580

581

581

582

+1.5

-1.9

2.1

86

198C

(mmol/L)

-5.0

5.61

198C

1.63

580

3.93

+2.3

3.83

-0.2

581

LDL cholesterol

1.14198B

2.2

2.6

580

582

1.10

1.90

581

198C

1.4033

2.11

non-HDL cholesterol

2.11

(mmol/L) 6.95Total cholesterol

33

-1.9

582(mmol/L)

(mmol/L)1.60

198A

198B

3.94

198B

+0.1

198A

Triglyceride

+2.5

582

5.16

198C -3.2

+0.8

3.7

3.76

1.8

198A

198B

-0.6

1.17HDL cholesterol

581

78

-3.3

580

198B582

3.7

If your laboratory is outside of the acceptable limits of performance for any its rolling time-window scores (A, B or C scores), this will be indicated by a red traffic light symbol. It is the responsibility of the laboratory to undertake an internal investigation to establish the underlying cause and put in place corrective and preventive action. Please do not wait to receive a formal notification of performance from the Scheme Organiser or the National Quality Assurance Advisory Panel (NQAAP) before logging the non-conformity and, where necessary, acting upon the data contained in your report. A green traffic light merely reflects that your laboratory is performing as well as the state-of-the-art allows; it does not necessarily mean that your assay / laboratory performance is good enough clinically. The A scores for Total cholesterol, HDL cholesterol and Triglyceride are all based on concentration- dependent degree of difficulty factors and, as such, are in the same ‘currency’ as the A scores in other Schemes. Non-HDL cholesterol, LDL cholesterol, VLDL cholesterol, Apolipoprotein B, Apolipoprotein A1, Lp(a) and Homocysteine do not yet have concentration-dependent degree of difficulty factors associated with them and so the 'A scores' for these analytes are only 'interim' at present.

You have until the close of Distribution 199 (24/06/2018) to submit late results / request amendments to results for Distribution 198. Please enter any late results or requests to amend non-analytical errors for Distribution 198 on the web under the usual Results button ensuring the correct Distribution number has been selected. You should include your name and a valid reason. Amending results is at the discretion of the Director and is not an automatic entitlement. We are not accepting any further requests to amend results or to change methods for Distribution 197.

Distribution 199 will be dispatched on 04/06/2018 . Results are due back in Birmingham by, notionally, 23:59 on 24/06/2018. Where your results appear as "XPL", it is because you did not report a numerical value for that analyte, but you did provide an explanation as to why a result was not reported.

of 22

Date : 20-May-2018

Minimum Analytical Performance Standards (MAPS)

Page 5


Distribution : 198

Laboratory :




B score% bias

Pool

with trend

Specimen MAPSC scorespecimen

ResultB score

with trendC score

MAPSMAPSTarget MAPSMAPS

1.40581(mmol/L)

-3.5

-1.6

5.2(mmol/L)Total cholesterol

5.25582

-2.41.19HDL cholesterol

6.9

1.17

2.7

198B582

198A

581

580 1.4

3.83198A

2.11

198B198C

-2.4580

198C

-1.0

3.7 m

m m

m

The concentration ranges for inclusion in MAPS analysis for Total cholesterol and HDL cholesterol are 3.0 to 7.0 mmol/L and 0.7 to 1.5 mmol/L respectively. The MAPS specimen %bias limits are 8.5% and 15.9% respectively (A green tick is a ‘pass’; a red cross is a ‘fail’). The MAPS B score Limits are 4.0% and 10.0% respectively (A green square is a ‘pass’; a red square is a ‘fail’). The MAPS C score Limits are 2.7% and 3.6% respectively (A green square is a ‘pass’; a red square is a ‘fail’). The trend arrows point upwards if there has been a marked improvement, and down if there has been a marked deterioration. A horizontal two-headed arrow signifies ‘no change’. Specimens are only included in the MAPS analysis if the triglyceride value is less than 2.0 mmol/L. No information will be displayed for any specimen failing any of the inclusion criteria. The MAPS B and C scores are calculated over a six month time-window. It is therefore possible to have updated rolling time-window MAPS B and C scores even if there are no usable specimens in the MAPS concentration range in the current distribution.

The All Laboratory Trimmed Mean (ALTM) is used as the target value for MAPS analysis. MAPS B scores and C scores and their associated symbols and trend arrows will only appear on your report if a sufficient number of specimens in the current time-window meet the criteria for inclusion in the MAPS analysis. The Minimum Analytical Performance Standards (MAPS) scoring system is a National Quality Assurance Advisory Panel (NQAAP) initiative which we, and other EQA providers, have been including on our reports from 1st May 2012 for Total cholesterol and HDL cholesterol. MAPS data provides useful additional information regarding how clinically relevant the result obtained by your laboratory was on any given specimen. Whilst MAPS is a useful additional feature, we can confirm that our full educational EQA design will continue to have ‘The ABC of EQA’ at its heart. All performance monitoring undertaken by Birmingham Quality will be based upon your A, B and C scores. Whilst we at Birmingham Quality are happy to explain our reporting conventions and styles in adhering to the MAPS principles, it is the NQAAP who are best-placed to provide the background and rationale. The NQAAP intend that MAPS will be applied by all EQA providers and will be applied to other clinical chemistry analytes in a phased manner. For more information about how to contact the NQAAP (Chemical Pathology), please see http://www.ukneqas.org.uk/content/PageServer.asp?S=960626227&C=1252&Type=G&ID=68 Not all analytes will immediately be suitable for MAPS, and similarly our probing EQA scheme design will not be restricted to the limited concentration ranges that underpin MAPS.

of 22

Date : 20-May-2018

Method Summary

Page 6


Distribution : 198

Laboratory :




medianMethod Your MethodMethod Principle

arrow

Units

A score A scoremedian

A score All labwith trend

4333

60

86

32

Siemens (Bayer) reagents [6TE]

Cholesterol oxidase (CDC)Total cholesterol

mmol/L

Siemens (Bayer) [2TE]

Sequential

29mmol/L

LDL cholesterol

53

116



mmol/L

mmol/L

non-HDL cholesterol

115

Sequential

Friedewald Equation

105Siemens (Bayer) [2TE]

Total glycerol GPO 86

HDL cholesterol

Triglyceride

mmol/L

35

33

78

Our method update service is web-based and is accessed online via the 'edit' button on the 'Results and Reports page'. You can select from a dropdown of methods or select the default option from the major manufacturer’s products*. *If you are not using the system according to the manufacturer's instructions, please select the in-house category within your system's method principle.

A s

core

Graphic Equalizer Plot of A scoresAll laboratories

P-BWATSCR2

LC

H

LT

G

LH

D

LN

HD

LLD

LV

D

LA

PO

B

LA

PO

A1

LLA

LH

Y

0

50

100

150

200

250

300

A s

core

Method Graphic Equalizer Plot of A scoresfor your methods

P-BWATSCM2

LC

H

LT

G

LH

D

LN

HD

LLD

LV

D

LA

PO

B

LA

PO

A1

LLA

LH

Y

0

50

100

150

200

250

300

of 22

Date : 20-May-2018

Cumulative Summary

Page 7


Distribution : 198

Laboratory :




B s

core

C score

Total cholesterol B score is -0.6 and C score is 2.1 Cholesterol oxidase (CDC) Siemens (Bayer) [2TE]

P-ABCPENR (ABCPENR)

0 5 10

-10

-5

0

5

10

Your labYour methodOverall (n=437)Your method (n=44)

B s

core

C score

Triglyceride B score is -0.1 and C score is 2.9 Total glycerol GPO Siemens (Bayer) reagents [2TE]

P-ABCPENR (ABCPENR)

0 5 10

-10

-5

0

5

10


B s

core

C score

HDL cholesterol B score is +1.4 and C score is 2.2 Sequential Siemens (Bayer) reagents [6TE]

P-ABCPENR (ABCPENR)

0 5 10 15

-15

-10

-5

0

5

10

15


B s

core

C score

non-HDL cholesterol B score is and C score is Sequential Siemens (Bayer) reagents [6TE]

P-ABCPENR (ABCPENR)

0 5 10 15

-15

-10

-5

0

5

10

15


B s

core

C score

LDL cholesterol B score is -1.9 and C score is 4.7 Friedewald Equation Siemens (Bayer) [2TE]

P-ABCPENR (ABCPENR)

0 5 10 15

-15

-10

-5

0

5

10

15


of 22

Date : 20-May-2018

Analyte : Total cholesterol (mmol/L)

Page 8


Distribution : 198

Laboratory :




Pooled human serum

582

Pool description / Treatments / Additions

198B Pooled human serumPooled human serum

Pool

581

Spec.

198A

198C

580 2.1

The B limit is +/-

Your B score is

The A limit is5.0

78

5.0

Your A score is-0.6

The C limit is

200

Your C score is

All methods Cholesterol oxidase (CDC) Siemens (Bayer) [2TE]

Specimen : 198A

3.2 3.5 3.8 4.1 4.4Total cholesterol (mmol/L)

0

20

40

60

80

100

120

no. of la

bora

tories

3.8647

4.03

Cholesterol oxidase (CDC)

3.83

Abbott [2AB]

3.43OCD (J&J) slides [1JJ]

0.09

3.0

128

15Beckman AU [3OL]

2.4

Beckman AU [2OL] 2.9

Dry slide

3.77

3.2

0.07

2.8

0.04

0.134.03

Randox [2RX]

15 2.4

473.2Cholesterol oxidase (NIST)

2.1

0.08

15

0.11

Mean

15

n

1.73.7

3.96

1.1

0.08

0.13

0.10

0.14

3.76

434

6Roche Mod/Cobas [2BO]

3.84

3.43

471

SD

In-house

3.9

Siemens (Bayer) [2TE]192

0.15

3.82

CV(%)

0.115

3.99

All methods [ALTM]

(reagent)

3.76(MLTM)

3.76

Standard Uncertainty

Accuracy Index

3.7

%bias

Your result

79


-1.6

0.02

Your specimen:

Target value

Specimen : 198B


0

20

40

60

80

100

120

no. of la

bora

tories

7.3147

7.60


7.20

Abbott [2AB]


0.06

2.5

128

15Beckman AU [3OL]

3.5


Dry slide

7.09

2.9

0.12

2.4

0.02

0.227.60

Randox [2RX]

15 3.5


0.8

0.21

15

0.17

Mean

15

n

1.63.9

7.48

0.3

0.21

0.22

0.17

0.28

6.95

434


7.22

5.94

471

SD

In-house

4.3


0.31

6.85

CV(%)

0.195

7.42

All methods [ALTM]

(reagent)

6.95(MLTM)

6.95


Accuracy Index

6.9

%bias

Your result

37


-0.8Your specimen:

0.03

Target value

Specimen : 198C


0

20

40

60

80

100

no. of la

bora

tories

5.3147

5.52


5.25

Abbott [2AB]


0.18

2.4

128

15Beckman AU [3OL]

1.8


Dry slide

5.16

3.2

0.08

2.1

0.02

0.175.52

Randox [2RX]

15 1.8


3.2

0.09

15

0.13

Mean

15

n

1.43.2

5.40

0.4

0.09

0.17

0.11

0.17

5.16

434


5.25

5.10

471

SD

In-house

3.3


0.17

5.23

CV(%)

0.165

5.54

All methods [ALTM]

(reagent)

5.16(MLTM)

5.16


Accuracy Index

5.2

%bias

Your result

42


+0.8Your specimen:

0.02

Target value

B s

core

Total cholesterol Median and IQRs of B scores

P-BWABCBR

1

1JJ 2

2A

B

2B

K

2O

L

2O

O

2R

X

2B

O

2T

E 3

3O

L

-10

-5

0

5

10

All

Gro

up

Meth

od

C s

core

Total cholesterol Median and IQRs of C scores

P-BWABCCR

1

1JJ 2

2A

B

2B

K

2O

L

2O

O

2R

X

2B

O

2T

E 3

3O

L

0

5

10

All

Gro

up

Meth

od

of 22

Pool

(exclusion)

[Type]

Distribution 193

26-Nov-2017

result target %bias

Distribution 194

31-Dec-2017

result target %bias

Distribution 195

11-Feb-2018

result target %bias

Distribution 196

18-Mar-2018

result target %bias

Distribution 197

22-Apr-2018

result target %bias

Distribution 198

20-May-2018

result target %bias

2.8 2.73 +2.4579 2.8 2.85 -1.7530

2.9 3.01 -3.5574 3.7 3.70 +0.1524

3.7 3.76 -1.6580 4.0 4.03 -0.7578

4.2 4.14 +1.5525 4.3 4.36 -1.3570 4.8 4.84 -0.8571

5.0 5.14 -2.8576 5.2 5.16 +0.8582

4.9 5.18 -5.4573 5.2 5.23 -0.6572

6.0 6.17 -2.7575 6.6 6.43 +2.6531 6.7 6.73 -0.4532

6.9 6.95 -0.8581 7.2 7.06 +2.0526

MethodmeanA scoreB scoreC score

2TE+1.2

48+0.9

1.1

2TE+0.2

55+1.0

1.4

2TE-0.9

46+0.5

1.3

2TE-3.9

710.02.1

2TE-0.4

77-0.42.3

2TE-0.5

78-0.62.1

Date : 20-May-2018

Analyte : Total cholesterol (mmol/L)

Page 9


Distribution : 198

Laboratory :




A s

core

Total cholesterol Median and IQRs of A scores

P-BWABCAT

1

1JJ 2

2A

B

2B

K

2O

L

2O

O

2R

X

2B

O

2T

E 3

3O

L

0

50

100

150

200

250

300

All

Gro

up

Meth

od

B s

core

Total cholesterol Median and IQRs of B scores

P-BWABCBR

1

1JJ 2

2A

B

2B

K

2O

L

2O

O

2R

X

2B

O

2T

E 3

3O

L

-10

-5

0

5

10

All

Gro

up

Meth

od

B s

core

C score


P-ABCPENR

0 5 10

-10

-5

0

5

10


C s

core

Total cholesterol Median and IQRs of C scores

P-BWABCCR

1

1JJ 2

2A

B

2B

K

2O

L

2O

O

2R

X

2B

O

2T

E 3

3O

L

0

5

10

All

Gro

up

Meth

od

of 22

Date : 20-May-2018

Total cholesterol mmol/L

Page 10


Distribution : 198

Laboratory :




Specim

en A

ccura

cy Index

Distribution

Specimen Accuracy Indexfor each specimen in time-window

P-ABCATS (ABC1)

193 194 195 196 197 198

0

50

100

150

200

250

300

A s

core

Distribution

A score by distributionYour current A score is 78

P-ABCAT (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

50

100

150

200

250

300

All

Gro

up

Meth

od

Specim

en %

bia

s

Distribution

Specimen %biasfor each specimen in time-window

P-ABCBRS (ABC1)

193 194 195 196 197 198

-10

-5

0

5

10

B s

core

Distribution

B score by distributionYour current B score is -0.6

P-ABCBR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

-10

-5

0

5

10

All

Gro

up

Meth

od

Diffe

rence (

mm

ol/L)

Concentration (mmol/L)

Difference (result - target)for each specimen in time-window

P-BA1FS1A (ABC1)

2 3 4 5 6 7 8 9 10

-0.50

-0.25

0.00

0.25

0.50

C s

core

Distribution

C score by distributionYour current C score is 2.1

P-ABCCR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

5

10

All M

eth

od

Specim

en %

bia

s



P-BA1FS1P (ABC1)

2 3 4 5 6 7 8 9 10

-10

-5

0

5

10

B s

core

C score


P-ABCPENR (ABC1)

0 5 10

-10

-5

0

5

10


Specim

en A

ccura

cy Index



P-YSTMOD (ABC1)

2 3 4 5 6 7 8 9 10

0

50

100

150

200

250

300 ALTMMLTM

CV

%


Total cholesterol Between-laboratory agreementSiemens (Bayer) [2TE]

P-PROFILE (ABC1)

2 3 4 5 6 7 8 9 10

0

5

10

15

of 22

Date : 20-May-2018

Analyte : Triglyceride (mmol/L)

Page 11


Distribution : 198

Laboratory :




Pooled human serum

582



Pool

581198A

Spec.

198C

580 2.9

The B limit is +/-

Your B score is

The A limit is5.0

86

7.5

-0.1Your A score is

The C limit is

200

Your C score is

All methods Total glycerol GPO Siemens (Bayer) reagents [2TE]

Specimen : 198A

1.0 1.3 1.6 1.9 2.2Triglyceride (mmol/L)

0

50

100

150

200

250

no. of la

bora

tories

1.5962

Total glycerol GPO

1.62

Abbott reagents [2AB]

15

Meann

1.93

3.6

OCD (J&J) slides [1JJ]

1.59

0.05

1283.9

1.61

Not stated, please specify

4

3.50.07

1.60

1.63

0.06


Dry slide

48187

Randox reagents [2RX]

444

6.6

1.93

1.620.06

466

0.06

In-house [2OO]Beckman reagents [2BK]

SD

3.8

4.3

4

1.67

15

Roche Mod/Cobas [2BO]

3.5


1.97

0.07

CV(%)

0.05

3.4

0.10

4

6

0.07

1.63

All methods [ALTM]

(reagent)

1.63(MLTM)

1.63


Accuracy Index

1.60

%bias

Your result

80


-1.9Your specimen:

0.01

Target value

Specimen : 198B


0

50

100

150

200

no. of la

bora

tories

3.9362

Total glycerol GPO

3.96


15

Meann

3.96

2.6


3.92

0.12

1283.2

3.95


4

2.50.10

3.90

3.99

0.13


Dry slide

48187


444

4.1

3.96

3.960.10

466

0.13


SD

3.2

3.2

4

4.05

15


2.5


5.15

0.13

CV(%)

0.12

3.1

0.16

4

6

0.10

3.94

All methods [ALTM]

(reagent)

3.94(MLTM)

3.94


Accuracy Index

3.93

%bias

Your result

9


-0.2Your specimen:

0.02

Target value

Specimen : 198C


0

50

100

150

200

250

300

no. of la

bora

tories

1.0862

Total glycerol GPO

1.11


15

Meann

1.13

3.7


1.09

0.02

1283.4

1.11


4

3.60.04

1.10

1.11

0.04


Dry slide

48187


444

3.8

1.13

1.110.04

466

0.03


SD

2.6

3.4

4

1.11

15


3.6


1.17

0.04

CV(%)

0.05

1.6

0.04

4

6

0.04

1.10

All methods [ALTM]

(reagent)

1.10(MLTM)

1.10


Accuracy Index

1.07

%bias

Your result

136


-3.2Your specimen:

0.00

Target value

B s

core

Triglyceride Median and IQRs of B scores

P-BWABCBR

1

1JJ 2

2A

B

2O

L

2R

X

2B

O

2T

E

-10

-5

0

5

10

All

Gro

up

Meth

od

C s

core

Triglyceride Median and IQRs of C scores

P-BWABCCR

1

1JJ 2

2A

B

2O

L

2R

X

2B

O

2T

E

0

5

10

All

Gro

up

Meth

od

of 22

Pool

(exclusion)

[Type]

Distribution 193

26-Nov-2017

result target %bias

Distribution 194

31-Dec-2017

result target %bias

Distribution 195

11-Feb-2018

result target %bias

Distribution 196

18-Mar-2018

result target %bias

Distribution 197

22-Apr-2018

result target %bias

Distribution 198

20-May-2018

result target %bias

0.59 0.57 +2.7530 0.56 0.57 -1.4579 0.79 0.81 -2.3578

1.12 1.10 +1.6572 1.07 1.10 -3.2582

1.24 1.25 -0.9576 1.27 1.27 +0.1524

1.54 1.48 +3.8573 1.61 1.59 +1.5531

1.60 1.63 -1.9580 1.94 1.89 +2.6575

2.03 2.02 +0.7532 2.07 2.13 -3.0570

2.76 2.83 -2.4525 2.99 2.91 +2.6574

3.76 3.87 -2.7571 3.93 3.94 -0.2581

4.08 4.02 +1.5526


2TE-0.3

101+2.0

2.5

2TE+1.6

83+1.6

1.9

2TE-1.4

93+1.5

2.3

2TE+3.0

104+1.7

2.6

2TE-1.5

80+0.5

2.5

2TE-1.8

86-0.12.9

Date : 20-May-2018

Analyte : Triglyceride (mmol/L)

Page 12


Distribution : 198

Laboratory :




A s

core

Triglyceride Median and IQRs of A scores

P-BWABCAT

1

1JJ 2

2A

B

2O

L

2R

X

2B

O

2T

E

0

50

100

150

200

250

300

All

Gro

up

Meth

od

B s

core

Triglyceride Median and IQRs of B scores

P-BWABCBR

1

1JJ 2

2A

B

2O

L

2R

X

2B

O

2T

E

-10

-5

0

5

10

All

Gro

up

Meth

od

B s

core

C score


P-ABCPENR

0 5 10

-10

-5

0

5

10


C s

core

Triglyceride Median and IQRs of C scores

P-BWABCCR

1

1JJ 2

2A

B

2O

L

2R

X

2B

O

2T

E

0

5

10

All

Gro

up

Meth

od

of 22

Date : 20-May-2018

Triglyceride mmol/L

Page 13


Distribution : 198

Laboratory :




Specim

en A

ccura

cy Index

Distribution


P-ABCATS (ABC1)

193 194 195 196 197 198

0

50

100

150

200

250

300

A s

core

Distribution


P-ABCAT (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

50

100

150

200

250

300

All

Gro

up

Meth

od

Specim

en %

bia

s

Distribution


P-ABCBRS (ABC1)

193 194 195 196 197 198

-10

-5

0

5

10

B s

core

Distribution


P-ABCBR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

-10

-5

0

5

10

All

Gro

up

Meth

od

Diffe

rence (

mm

ol/L)



P-BA1FS1A (ABC1)

0 1 2 3 4 5

-0.50

-0.25

0.00

0.25

0.50

C s

core

Distribution


P-ABCCR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

5

10

All

Meth

od

Specim

en %

bia

s



P-BA1FS1P (ABC1)

0 1 2 3 4 5

-10

-5

0

5

10

B s

core

C score


P-ABCPENR (ABC1)

0 5 10

-10

-5

0

5

10


Specim

en A

ccura

cy Index



P-YSTMOD (ABC1)

0 1 2 3 4 5

0

50

100

150

200

250

300 ALTMMLTM

CV

%


Triglyceride Between-laboratory agreementSiemens (Bayer) reagents [2TE]

P-PROFILE (ABC1)

0 1 2 3 4 5

0

5

10

15

20

25

of 22

Date : 20-May-2018

Analyte : HDL cholesterol (mmol/L)

Page 14


Distribution : 198

Laboratory :




Pooled human serum

582



Pool

581198A

Spec.

198C

580 2.2

The B limit is +/-

Your B score is

The A limit is10.0

33

10.0

+1.4Your A score is

The C limit is

200

Your C score is

All methods Sequential Siemens (Bayer) reagents [6TE]

Specimen : 198A

0.6 0.9 1.2 1.5 1.8HDL cholesterol (mmol/L)

0

50

100

150

200

no. of la

bora

tories

1.0860

1.33

PEG Enzymes

1.19


1.22OCD (J&J) dHDL slides [1JJ2]

0.06

5.2

183

124Abbott reagents [7AB]

3.0

Ag/Ab complex 3.5

Dry slide

1.16

4.3

0.05

4.3

0.03

0.061.33

Sequential

13 3.1

474.3ASDM

5.0

0.04

122

0.06

Mean

10

n

4.34.3

1.15

3.2

0.04

0.06

0.05

0.05

1.14

186

55Randox reagents [6RX]

1.15

1.21

451

SD

Beckman AU [5OL]

9.4

Siemens (Bayer) reagents [6TE]6

0.11

1.08

CV(%)

0.0458

1.14

All methods [ALTM]

(reagent)

1.14(MLTM)

1.14


Accuracy Index

1.17

%bias

Your result

47


+2.5Your specimen:

0.01

Target value

Specimen : 198B


0

50

100

150

200

no. of la

bora

tories

1.1960

1.54

PEG Enzymes

1.26



0.07

4.6

180


3.8

Ag/Ab complex 5.1

Dry slide

1.42

4.2

0.11

2.3

0.05

0.061.54

Sequential

13 5.0

474.2ASDM

4.9

0.05

122

0.06

Mean

10

n

10.810.9

1.06

4.5

0.06

0.06

0.03

0.11

1.37

183


1.05

1.28

448

SD

Beckman AU [5OL]

20.1


0.25

1.18

CV(%)

0.0658

1.37

All methods [ALTM]

(reagent)

1.37(MLTM)

1.37


Accuracy Index

1.40

%bias

Your result

45


+2.3Your specimen:

0.01

Target value

Specimen : 198C


0

50

100

150

200

no. of la

bora

tories

1.8960

2.27

PEG Enzymes

2.11



0.08

3.7

183


2.9

Ag/Ab complex 4.2

Dry slide

2.08

4.0

0.06

4.4

0.07

0.092.27

Sequential

13 2.7

473.9ASDM

3.9

0.06

122

0.08

Mean

10

n

3.13.1

2.06

3.7

0.06

0.09

0.09

0.06

2.11

186


2.06

2.16

451

SD

Beckman AU [5OL]

7.0


0.15

1.89

CV(%)

0.0858

2.11

All methods [ALTM]

(reagent)

2.11(MLTM)

2.11


Accuracy Index

2.11

%bias

Your result

2


+0.1Your specimen:

0.02

Target value

B s

core

HDL cholesterol Median and IQRs of B scores

P-BWABCBR

1

1JJ2 3

3B

O 5

5O

L 6

6R

X

6T

E 7

7A

B

-15

-10

-5

0

5

10

15

AllG

roup

Meth

od

C s

core

HDL cholesterol Median and IQRs of C scores

P-BWABCCR

1

1JJ2 3

3B

O 5

5O

L 6

6R

X

6T

E 7

7A

B

0

5

10

15

All

Gro

up

Meth

od

of 22

Pool

(exclusion)

[Type]

Distribution 193

26-Nov-2017

result target %bias

Distribution 194

31-Dec-2017

result target %bias

Distribution 195

11-Feb-2018

result target %bias

Distribution 196

18-Mar-2018

result target %bias

Distribution 197

22-Apr-2018

result target %bias

Distribution 198

20-May-2018

result target %bias

0.63 0.62 +1.2574 0.73 0.72 +0.9525

0.92 0.91 +0.6571 0.94 0.93 +1.6524

0.93 0.94 -0.7530 1.00 0.97 +3.5579

1.17 1.14 +2.5580 1.29 1.23 +4.5526

1.40 1.37 +2.3581 1.54 1.47 +4.5578

1.61 1.60 +0.9570 1.61 1.63 -1.2573

1.68 1.64 +2.6572 1.86 1.79 +3.6576

1.87 1.89 -0.9575 2.11 2.11 +0.1582

2.12 2.14 -0.9532 2.76 2.74 +0.7531


6TE+2.3

40+0.5

2.8

6TE-0.3

39+0.6

2.7

6TE+1.4

41+0.7

2.7

6TE-0.3

29+1.0

2.2

6TE+3.9

29+1.0

2.2

6TE+1.6

33+1.4

2.2

Date : 20-May-2018

Analyte : HDL cholesterol (mmol/L)

Page 15


Distribution : 198

Laboratory :




A s

core

HDL cholesterol Median and IQRs of A scores

P-BWABCAT

1

1JJ2 3

3B

O 5

5O

L 6

6R

X

6T

E 7

7A

B

0

50

100

150

200

250

300

All G

roup

Meth

od

B s

core

HDL cholesterol Median and IQRs of B scores

P-BWABCBR

1

1JJ2 3

3B

O 5

5O

L 6

6R

X

6T

E 7

7A

B

-15

-10

-5

0

5

10

15

AllG

roup

Meth

od

B s

core

C score


P-ABCPENR

0 5 10 15

-15

-10

-5

0

5

10

15


C s

core

HDL cholesterol Median and IQRs of C scores

P-BWABCCR

1

1JJ2 3

3B

O 5

5O

L 6

6R

X

6T

E 7

7A

B

0

5

10

15

All

Gro

up

Meth

od

of 22

Date : 20-May-2018

HDL cholesterol mmol/L

Page 16


Distribution : 198

Laboratory :




Specim

en A

ccura

cy Index

Distribution


P-ABCATS (ABC1)

193 194 195 196 197 198

0

50

100

150

200

250

300

A s

core

Distribution


P-ABCAT (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

50

100

150

200

250

300

All G

roup

Meth

od

Specim

en %

bia

s

Distribution


P-ABCBRS (ABC1)

193 194 195 196 197 198

-15

-10

-5

0

5

10

15

B s

core

Distribution

B score by distributionYour current B score is +1.4

P-ABCBR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

-15

-10

-5

0

5

10

15

AllG

roup

Meth

od

Diffe

rence (

mm

ol/L)



P-BA1FS1A (ABC1)

0.0 0.5 1.0 1.5 2.0 2.5 3.0

-1.0

-0.5

0.0

0.5

1.0

C s

core

Distribution


P-ABCCR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

5

10

15

All

Meth

od

Specim

en %

bia

s



P-BA1FS1P (ABC1)

0.0 0.5 1.0 1.5 2.0 2.5 3.0

-15

-10

-5

0

5

10

15

B s

core

C score


P-ABCPENR (ABC1)

0 5 10 15

-15

-10

-5

0

5

10

15


Specim

en A

ccura

cy Index



P-YSTMOD (ABC1)

0.0 0.5 1.0 1.5 2.0 2.5 3.0

0

50

100

150

200

250

300 ALTMMLTM

CV

%


HDL cholesterol Between-laboratory agreementSiemens (Bayer) reagents [6TE]

P-PROFILE (ABC1)

0.0 0.5 1.0 1.5 2.0 2.5 3.0

0

5

10

15

20

25

of 22

Date : 20-May-2018

Analyte : non-HDL cholesterol (mmol/L)

Page 17


Distribution : 198

Laboratory :




Pooled human serum

582



Pool

581198A

Spec.

198C

580

The B limit is +/-

Your B score is

The A limit is10.010.0

Your A score is

The C limit is

200

Your C score is

All methods Sequential Siemens (Bayer) reagents [6TE]

Specimen : 198A

2.0 2.3 2.6 2.9 3.2non-HDL cholesterol (mmol/L)

0

20

40

60

80

no. of la

bora

tories

30Beckman AU [5OL]

4.0

2.66

4.0PEG Enzymes

Meann

129

0.13

2.26

2.64

0.10

Ag/Ab complex0.11

30


0.11

3.7


2.66

2.64

2.644.5

0.13

Dry slide

4040



4.0

2.26

1292.82

232

0.10

2.644.5

SD

3.9

4.7

5

4.0

3

ASDM

3


20

0.12

0.10

CV(%)

2.82

3.9

0.11Sequential

20

2.64

2.64

All methods [ALTM]

(reagent)

2.64(MLTM)

2.64


Accuracy Index%bias

Your result


Your specimen:

0.03

Target value

Specimen : 198B


0

20

40

60

80

no. of la

bora

tories

30Beckman AU [5OL]

3.5

5.98

3.5PEG Enzymes

Meann

126

0.31

4.75

5.61

0.13

Ag/Ab complex0.21

30


0.20

5.2


5.75

5.94

6.025.0

0.31

Dry slide

4040



3.6

4.75

1266.20

229

0.13

5.615.0

SD

2.1

4.3

5

3.6

3

ASDM

3


20

0.26

0.30

CV(%)

6.20

2.1

0.20Sequential

20

6.02

5.94

All methods [ALTM]

(reagent)

5.61(MLTM)

5.61


Accuracy Index%bias

Your result


Your specimen:

0.06

Target value

Specimen : 198C


0

10

20

30

40

50

60

70

no. of la

bora

tories

30Beckman AU [5OL]

4.0

3.15

4.0PEG Enzymes

Meann

129

0.24

2.97

3.10

0.12

Ag/Ab complex0.12

30


0.16

14.6


3.01

3.16

3.116.8

0.24

Dry slide

4040



5.0

2.97

1293.49

232

0.12

3.106.8

SD

3.8

5.3

5

5.0

3

ASDM

3


20

0.17

0.44

CV(%)

3.49

3.8

0.16Sequential

20

3.11

3.16

All methods [ALTM]

(reagent)

3.10(MLTM)

3.10


Accuracy Index%bias

Your result


Your specimen:

0.05

Target value

B s

core

non-HDL cholesterol Median and IQRs of B scores

P-BWABCBR

3

3B

O 5

5O

L 6

6T

E 7

7A

B

-15

-10

-5

0

5

10

15

All

Gro

up

Meth

od

C s

core

non-HDL cholesterol Median and IQRs of C scores

P-BWABCCR

3

3B

O 5

5O

L 6

6T

E 7

7A

B

0

5

10

15

All G

roup

Meth

od

of 22

Pool

(exclusion)

[Type]

Distribution 193

26-Nov-2017

result target %bias

Distribution 194

31-Dec-2017

result target %bias

Distribution 195

11-Feb-2018

result target %bias

Distribution 196

18-Mar-2018

result target %bias

Distribution 197

22-Apr-2018

result target %bias

Distribution 198

20-May-2018

result target %bias

1.80579 1.91530

2.40574 2.58578

2.64580 2.73570

2.78524 3.10582

3.39525 3.40576

3.58572 3.58573

3.68531 3.90571

4.34575 4.59532

5.61581 5.82526

Method

A scoreB scoreC score

6TE 6TE 6TE 6TE 6TE 6TE

Date : 20-May-2018

Analyte : non-HDL cholesterol (mmol/L)

Page 18


Distribution : 198

Laboratory :




A s

core

non-HDL cholesterol Median and IQRs of A scores

P-BWABCAT

3

3B

O 5

5O

L 6

6T

E 7

7A

B

0

50

100

150

200

250

300

All

Gro

up

Meth

od

B s

core

non-HDL cholesterol Median and IQRs of B scores

P-BWABCBR

3

3B

O 5

5O

L 6

6T

E 7

7A

B

-15

-10

-5

0

5

10

15

All

Gro

up

Meth

od

B s

core

C score


P-ABCPENR

0 5 10 15

-15

-10

-5

0

5

10

15


C s

core

non-HDL cholesterol Median and IQRs of C scores

P-BWABCCR

3

3B

O 5

5O

L 6

6T

E 7

7A

B

0

5

10

15

All G

roup

Meth

od

of 22

Date : 20-May-2018

non-HDL cholesterol mmol/L

Page 19


Distribution : 198

Laboratory :




Specim

en A

ccura

cy Index

Distribution


P-ABCATS (ABC1)

193 194 195 196 197 198

0

50

100

150

200

250

300

A s

core

Distribution

A score by distributionYour current A score is

P-ABCAT (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

50

100

150

200

250

300

All

Gro

up

Meth

od

Specim

en %

bia

s

Distribution


P-ABCBRS (ABC1)

193 194 195 196 197 198

-15

-10

-5

0

5

10

15

B s

core

Distribution

B score by distributionYour current B score is

P-ABCBR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

-15

-10

-5

0

5

10

15

All

Gro

up

Meth

od

Diffe

rence (

mm

ol/L)



P-BA1FS1A (ABC1)

1 2 3 4 5 6 7 8

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

C s

core

Distribution

C score by distributionYour current C score is

P-ABCCR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

5

10

15

All M

eth

od

Specim

en %

bia

s



P-BA1FS1P (ABC1)

1 2 3 4 5 6 7 8

-15

-10

-5

0

5

10

15

B s

core

C score


P-ABCPENR (ABC1)

0 5 10 15

-15

-10

-5

0

5

10

15


Specim

en A

ccura

cy Index



P-YSTMOD (ABC1)

1 2 3 4 5 6 7 8

0

50

100

150

200

250

300 ALTMMLTM

CV

%


non-HDL cholesterol Between-laboratory agreementSiemens (Bayer) reagents [6TE]

P-PROFILE (ABC1)

1 2 3 4 5 6 7 8

0

5

10

15

20

of 22

Date : 20-May-2018

Analyte : LDL cholesterol (mmol/L)

Page 20


Distribution : 198

Laboratory :




Pooled human serum

582



Pool

581198A

Spec.

198C

580 4.7

The B limit is +/-

Your B score is

The A limit is10.0

33

10.0

-1.9Your A score is

The C limit is

200

Your C score is

All methods Friedewald Equation Siemens (Bayer) [2TE]

Specimen : 198A

1.4 1.7 2.0 2.3 2.6LDL cholesterol (mmol/L)

0

20

40

60

80

100

120

140

no. of la

bora

tories

1.90158

1.97

Beckman AU [2OL]

1.92

OCD (J&J) [2JJ]

1.91Abbott [2AB]

0.20

7.3

6

6Not stated, please specify

4.3

Roche Mod/Cobas [2BO] 5.5

Friedewald Equation

1.91

8.9

0.17

5.8

0.12

0.181.81

Measured LDL

359 6.6

63.2Roche Mod/Cobas [3BO]

10.1

0.08

6

0.17

Mean

96

n

13.26.0

1.30

6.3

0.13

0.06

0.11

0.13

2.41

49


2.09

1.92

409

SD


7.0

Randox reagents [3RX]16

0.13

1.90

CV(%)

0.1145

2.00

All methods [ALTM]

(reagent)

1.90(MLTM)

1.90


Accuracy Index

1.8

%bias

Your result

50


-5.0Your specimen:

0.02

Target value

Specimen : 198B


0

20

40

60

80

100

120

140

no. of la

bora

tories

4.22141

4.00

Beckman AU [2OL]

4.14

OCD (J&J) [2JJ]

4.15Abbott [2AB]

0.47

8.1

6


2.8


Friedewald Equation

4.05

5.0

0.28

4.8

0.20

0.203.62

Measured LDL

333 5.8


11.2

0.12

5

0.42

Mean

99

n

9.85.0

2.85

5.2

0.24

0.13

0.19

0.22

5.19

40


4.40

4.16

382

SD


6.4


0.26

3.83

CV(%)

0.2045

4.17

All methods [ALTM]

(reagent)

3.83(MLTM)

3.83


Accuracy Index

3.7

%bias

Your result

33


-3.3Your specimen:

0.04

Target value

Specimen : 198C


0

20

40

60

80

100

120

no. of la

bora

tories

2.59158

2.67

Beckman AU [2OL]

2.65

OCD (J&J) [2JJ]

2.65Abbott [2AB]

0.26

4.8

6


4.3


Friedewald Equation

2.68

6.6

0.16

5.6

0.15

0.182.75

Measured LDL

363 6.3


9.4

0.11

6

0.16

Mean

100

n

6.76.7

2.38

5.9

0.17

0.10

0.15

0.20

3.27

49


2.95

2.64

413

SD


6.6


0.18

2.56

CV(%)

0.1245

2.77

All methods [ALTM]

(reagent)

2.56(MLTM)

2.56


Accuracy Index

2.6

%bias

Your result

15


+1.5Your specimen:

0.03

Target value

B s

core

LDL cholesterol Median and IQRs of B scores

P-BWABCBR

2

2A

B

2O

L

2JJ

2B

O

2T

E 3

3A

B

3R

X

3B

O

-15

-10

-5

0

5

10

15

All

Gro

up

Meth

od

C s

core

LDL cholesterol Median and IQRs of C scores

P-BWABCCR

2

2A

B

2O

L

2JJ

2B

O

2T

E 3

3A

B

3R

X

3B

O

0

5

10

15

All

Gro

up

Meth

od

of 22

Pool

(exclusion)

[Type]

Distribution 193

26-Nov-2017

result target %bias

Distribution 194

31-Dec-2017

result target %bias

Distribution 195

11-Feb-2018

result target %bias

Distribution 196

18-Mar-2018

result target %bias

Distribution 197

22-Apr-2018

result target %bias

Distribution 198

20-May-2018

result target %bias

0.9 1.06 -15.1574 1.5 1.49 +0.4579

1.6 1.64 -2.5530 1.7 1.78 -4.4570

1.8 1.90 -5.0580 2.2 2.13 +3.2525

2.1 2.17 -3.2578 2.2 2.17 +1.4571

2.2 2.19 +0.2524 2.6 2.56 +1.5582

2.6 2.77 -6.3576 2.6 2.83 -8.3573

3.1 2.99 +3.8531 3.0 3.08 -2.5572

3.2 3.41 -6.3575 3.7 3.68 +0.5532

3.7 3.83 -3.3581 4.1 4.00 +2.6526


2TE+2.0

18+0.9

2.2

2TE+0.6

20+1.2

2.2

2TE-1.8

21+0.5

2.8

2TE-9.9

27-1.24.2

2TE-3.0

29-1.34.4

2TE-2.3

33-1.94.7

Date : 20-May-2018

Analyte : LDL cholesterol (mmol/L)

Page 21


Distribution : 198

Laboratory :




A s

core

LDL cholesterol Median and IQRs of A scores

P-BWABCAT

2

2A

B

2O

L

2JJ

2B

O

2T

E 3

3A

B

3R

X

3B

O

0

50

100

150

200

250

300

All

Gro

up

Meth

od

B s

core

LDL cholesterol Median and IQRs of B scores

P-BWABCBR

2

2A

B

2O

L

2JJ

2B

O

2T

E 3

3A

B

3R

X

3B

O

-15

-10

-5

0

5

10

15

All

Gro

up

Meth

od

B s

core

C score


P-ABCPENR

0 5 10 15

-15

-10

-5

0

5

10

15


C s

core

LDL cholesterol Median and IQRs of C scores

P-BWABCCR

2

2A

B

2O

L

2JJ

2B

O

2T

E 3

3A

B

3R

X

3B

O

0

5

10

15

All

Gro

up

Me

thod

of 22

Date : 20-May-2018

LDL cholesterol mmol/L

Page 22


Distribution : 198

Laboratory :




Specim

en A

ccura

cy Index

Distribution


P-ABCATS (ABC1)

193 194 195 196 197 198

0

50

100

150

200

250

300

A s

core

Distribution


P-ABCAT (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

50

100

150

200

250

300

All

Gro

up

Meth

od

Specim

en %

bia

s

Distribution


P-ABCBRS (ABC1)

193 194 195 196 197 198

-15

-10

-5

0

5

10

15

B s

core

Distribution


P-ABCBR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

-15

-10

-5

0

5

10

15

All

Gro

up

Meth

od

Diffe

rence (

mm

ol/L)



P-BA1FS1A (ABC1)

1 2 3 4 5 6 7

-1.0

-0.5

0.0

0.5

1.0

C s

core

Distribution


P-ABCCR (ABC1)

187 188 189 190 191 192 193 194 195 196 197 198

0

5

10

15

All M

eth

od

Specim

en %

bia

s



P-BA1FS1P (ABC1)

1 2 3 4 5 6 7

-15

-10

-5

0

5

10

15

B s

core

C score


P-ABCPENR (ABC1)

0 5 10 15

-15

-10

-5

0

5

10

15


Specim

en A

ccura

cy Index



P-YSTMOD (ABC1)

1 2 3 4 5 6 7

0

50

100

150

200

250

300 ALTMMLTM

CV

%


LDL cholesterol Between-laboratory agreementSiemens (Bayer) [2TE]

P-PROFILE (ABC1)

1 2 3 4 5 6 7

0

5

10

15

20

25

of 22

Documents

198 Date : 20-May-2018 Feedback · Date : 20-May-2018 Feedback Page 1 for Lipid Investigations Distribution : 198 Laboratory : Birmingham Quality is part of the University Hospitals