October, 1976 Vol. Nine No. Four

OFFICIAL QUARTERLY JOURNAL

OF

OFFICERS

Vice President Second V i m President H. M. Sinclair, M. D., 0. Sc. Prof. S. S. Jolly, M.D.

Laboratory of Human Nutrit ion Medical College Oxon, England Patiala, India

President Prof. G. W. Miller, Ph. D.

Utah State University Logan, Utah

Secretary G. L. Waldbon, M.D.

Warren, Michigan

Treasurer P. E. Zanfagna, M.D.

Lawrence, Massachusms

ADVISORY BOARD

Prof. G. Fradi, M.D. J. V. Marhold, M. D., Ph. D. Institute of Occupational Research Institute for Coon Rapids, Minnesota Medicine Organic Syntheais

Pardubice, CSSR

, Prof. J. B. Patrick, Ph. D. Mary Baldwin College

Staunton, Virginia

A. H. S i i q u i , M.D.

University o f Palerrno, Italy

Prof. Ren6 Truhaut, Ph. D. Prof. G. Halbwachs, Ph. D. Facult6 De Pharmacie Institute of Botany

Vienna, Austria Universiti de Paris, France

Prof. Dr. G. Rosenberger

Hannover, Germany

Prof. F. Pinet, M.D. Veterinary University Rhane, France

Prof. A. W. Burgstahler, Ph. D. University of Kansas

Lawrence, Kansas

EDITORIAL BOARD

MUDr. G. Baluova CSc. Prof. G. Neil Jenkins Prof. Frederick W. Oehtne. D.V.S. Research Institute for Hygiene The Dental School, Univ. of Kansas State University

Bratislava, Czechoslovakia Newcastle Upon Tyne, Manhattan, Kansas England

Dr. Ernest Bovay, Director J e n y Krechniak, Ph. D. Federal Agric. Research Station Akademia Medyana, Temple University

Liebefeld Bern, Switzerland Gdahsk, Poland Philadelphia, Pa.

Prof. Albert Schatz, Ph. D.

J. Franke, M.D. Martin Luther Universtgt

Halle/Saale, DDR

John R. McLaren, M.D. Robert Winship Memorial Clinic

Emory University Atlanta, Georgia

H. Hanhijarvi, D. D. S. Korpilahti. Finland

K.A.V.R. Krishnamachari, M.D. National Institute of Nutrit ion Hyderabal, India

Carlo Mangoni di S. Stefano, M. D. Institute of Human Physiology

University of Naples, Italy

Prof. S. P. S. Teotia, M. D. Department of Human Metabolism

Medical College University of Meerut, India.

Vol. Nine No. Four October, 1976 Pages 170-224

FLUORIDE Quarterly Reports

Issued by THE INTERNATIONAL SOCIETY FOR FLUORIDE RESEARCH

Editor G. L. Waldbqtt, M. D.

Warren, Michigan

Co-Editors A. W. Burgstahler, Ph. D.

Lawrence, Kansas J. A. Yiamouyiannis, Ph. D.

Monrovia. California

EDITORIAL Industrial Fluorosis ......................................... 170

ORIGINAL ARTICLES Effects of Fluoride on Blood Platelets - by E.H. Milrer, Philadel-

phia, Pennsylvania ...................................... 173

Endemic Genu Valgum, A New Dimension to the Fluorosis Prob- lem in India - by K.A.V.R. Krishnamachari and B. Sivakumar, Hyderabad, India ........................................ 185

Fluoride in Spanish Bottled Waters - by 0. Mazarrasa and J.A. Lazuen, Santander, Spain ................................ 201

The Uptake of Sodium Monofluoroacetate by Plants and Its Physiological Effects - by J.A. Cooke, Sunderland, U.K. .... 204

The Role of Calcium and Fluoride in Osteoporosis in Rhesus Monkeys - by H.J. Griffiths, R.D. Hunt, R.E. Zimmerman, H. Finberg and J. Cuttino, Boston, Massachusetts.. . . . . . . . . . .

Prevention of Bony Fluorosis in Aluminum Smelter Workers - by B.D. Dinman, W.J. Bovard, T.B. Bonney, J.M. Cohen, and M.O. Colwell, Pittsburgh, Pa. .............................

Langteitergebnisse nach Kollektiven Mundspclungen mit Nat- riurn Fluorid Losung in der Republik Kuba - by V.W. Kunzel, F. Soto, J. Maiwald, and R.C. Borroto, Leipzig, DDR and Habana, Cuba ........................................... 216

ABSTRACTS

213

215

Effect of Fluoride on Uptake and Loss of Fluoride in Superficial Enamel In Vivo . by G. Ahrens, Hamburg, Germany . . . . . . . 217

Normal Values of Fluoride from a Defined Region of the Human iliac Crest - by B. Shellman and A. Zober, Erlangen, DBR . . 218

including postage $18.00; Single copies $5.00.

Relationships of Human Plasma Fluoride and Bone Fluoride to Age- by F.M. Parkins, N. Tinanoff, M. Moutinho, M.B. Anstey, and M.H. Waziri, Iowa City, Iowa ......................... 218

Index ...................................................... 220

The In te rna t iona l Society f o r Fluoride Research will hold its Eighth Conference in London, England, May 2931, 1977. F u r t h e r d e t a i l s will appear in subsequent issues . The Program C o m m i t t e e is sol ic i t ing a b s t r a c t s (UP t o 300 words) of papers t o be presented a t t h e conference dealing w i t h any phase of fluoride research. Society 's o f f ice , P.O. Box 692, Warren, MI 48090. The deadline f o r t h e a b s t r a c t s will be January 1, 1977.

Kindly send a b s t r a c t s t o t h e

FLUORIDE it published quarterly by THE INTERNATIONAL SOCIETY FOR FLUORIDE RESEARCH, INC.,

MANUSCRIPTS for publication should be submitted in English, double-spaced with generous margins. References should be anangad according to the order in which they are cited in the text, and written as follows: Author, title, journal, volume, pages and year. Each paper must contain a summary of not more than 12 lines.

Contributors will receive copies of the issue of FLUORIDE containing their paper, free of charge.

FLUORIDE is listed in Current Contents Agricultural Food and Veterinary Sciences

218

NORMAL VALUES OF FLUORIDE FROM A DEFINED REGION OF THE HUMAN ILIAC CREST

B. Shellman and A. Zober Erlangen, DBR

(Abstracted f rom Int. Arch. Occup. Environ. Hlth. 35: 233244, 1975)

The authors assayed the fluoride concentration of t h e human iliac crest (dried bone) of 100 cadavers of both sexes using the ion sensitive electrode. A linear relationship between fluoride content and age was s ta t is t ical ly positive. The values ranged from a low of 69 p p in a girl aged 3 1/2 years who died of meningitis t o 1740 ppm in a 85 year old male who succumbed t o pulmunary embolism. In con t r a s t t o other authors, Shellman e t al. found no leveling off of fluoride concentrations a f t e r age 50.

......................

RELATIONSHIPS O F HUMAN PLASMA FLUORIDE AND BONE FLUORIDE TO AGE *

F. M. Parkins, N. Tinanoff, M. Moutinho, M. B. Anstey, and M. H. Waziri

Iowa City, Iowa

(Abstracted from the Calcif. Tiss. Res. 16: 335-338, 1974)

There is evidence t h a t fluoride levels in plasma correlate with the fluoride content in bones. The authors determined whether o r not fluo- ride in plasma and bones might correlate with age.

In 41 inpatients a t the University Hospital, Iowa City, 36 of whom had been residing in fluoridated communities plasma fluoride was deter- mined in the fasting s tage by the fluoride ion selective electrode. For bone fluoride, the iliac crests on 20 autopsied cases were examined 19

*See page 169, July 1976

FLUORIDE