14 Radiation

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    Biological Effects of

    Ionizing Radiation

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    Biological Effects of Ionizing

    Radiation

    Photons or moving particles that have

    sufficient energy to knock electrons out of

    atoms / molecules These include x-rays, gamma rays, alpha

    particles, and beta particles.

    Harmful to humans because these canalter significantly the structure of

    molecules in cells.

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    Biological Effects of Ionizing

    Radiation

    The energy absorbed by

    biological tissues per unit mass.

    SI Unit = gray (Gy) = 1 J/kg, butthe unit most often used is the

    rad = 0.01 Gy = 0.01 J / kg.

    The amount of biological damage

    depends on the type of ionizing

    radiation. To make a comparison, we

    use...

    effectbiologicalsame

    theproducesthatradiationofDose

    effectbiologicalcertainaproducetorays-xkeV200ofDose

    RBE

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    Biological Effects of Ionizing

    Radiation

    Type of Radiation RBE

    200 keV x-rays 1

    gamma rays 1beta particles 1

    protons 10

    alpha particles 10-20

    slow neutrons 2

    fast neutrons 10 A 200 Gy dose of x-rays

    does the same amount of

    damage as a 20 Gy dose of

    fast neutrons.

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    Biological Effects of Ionizing

    Radiation

    The RBE is often used in conjunction with the absorbed

    dose to give the Biologically Equivalent Dose (BED) in rems.

    BED = AD RBE

    This reflects the damage-producing character of the radiation.

    Source of Radiation BED (mrem/yr)

    cosmic rays 28

    earth & air 28

    internal nuclei (C, K) 39

    inhaled radon ~200

    consumer products 10

    medical diagnostics 39

    nuclear medicine 14

    360

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    Biological Effects of Ionizing

    Radiation

    For the kinds of low doses of radiation

    that we receive every day, cells can

    usually repair the damage.

    At higher doses (up to 100 rem), thecells may not be able to repair the

    damagethey are either damaged or

    dead. Dead cells do not matter since

    they can be replaced.

    Damaged cells may produce abnormalcells when they divide. Under the right

    circumstances, these cells can become

    cancerous. This is the origin of our

    increased risk of cancer due to radiation

    exposure.

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    Biological Effects of Ionizing

    Radiation

    At even higher doses, the cells cannot be replaced and

    tissues fail to function.

    > 100 remwhole body

    Radiation Sickness...intestinal damage, nausea,

    general weaknes

    >300 rem whole body

    immune system damage

    >400 rem

    whole bodyno medical attention will result in death for 50 %

    of people in this condition within 60 days

    >1000 rem whole body

    vascular damage and death for 100 % of people

    ...but with adequate safety measures in place, no one is expected

    to receive more than 5 rem in a year. So, the real risks we need

    to consider are the long term ones...

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    Biological Effects of Ionizing

    Radiation

    What about non-ionizing radiation?

    Type of Radiation effects

    UV chemical changes

    visible heating

    microwaves more heating

    very long waves molecular changes?

    ...not the same kind of damage that ionizing radiation does...

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    Biological Effects of Ionizing

    Radiation

    How much will radiation exposure increase my chances of death

    from cancer?

    The current US death rate from cancer is 20 %.So, out of every 100 people 20 of them, through random

    processes will die from cancer.

    If I take 10 000 people and expose them to 1 rem to their

    whole body, eight additional people will get cancer, sostatistically we would expect around 2008 cancer deaths.

    If the exposure is over the course of a year, then there will

    be only 2 to 4 additional cases.

    A better way to look at risks is by the number of days

    lost to an average life in a population...

    smoking 20 cigarettes per day 6 years

    15 % overweight 2 years

    alcohol (average US consumption) 1 yearall accidents 207 days

    natural hazards 7 days

    occupational dose (300 mrem/yr) 15 days

    occupational dose (1 rem/yr) 51 days

    You can do the same thing with risks on the job:

    all industries 60 days

    agriculture 320 daysconstruction 227 days

    mining / quarrying 167 days

    manufacturing 40 days

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    Biological Effects of Ionizing

    Radiation

    Receiving 10 mrem of radiation will cause death for one in one

    million persons. This same rate is achieved by...

    smoking 1.4 cigarettes

    eating 40 tablespoons of peanut butter

    spending 2 days in New York City (air pollution)

    driving 40 miles in a car

    flying 2500 miles in a jetcanoeing for 6 minutes

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    Biological Effects of Ionizing

    Radiation

    So what about nuclear power?

    US public exposure from nuclear power

    is < 0.1 mrem/yr

    coal burning power plant 0.165 mrem/yr

    x-rays from TVs 0.500 mrem/hr

    airplane ride (39 000 ft) 0.500 mrem/hr

    nuclear power plant site 0.600 mrem/yr

    natural gas in your home 9 mrem/yr

    Three Mile Island event 80 mrem/event

    at the plant

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    Biological Effects of Ionizing

    Radiation

    So, how do I minimize my risk?

    minimize time of exposure

    maximize your distance from the source