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10 1 10 2 1 2 3 4 5 iPS piPS 10 3 10 4 10 5 10 6 Cell number Passage number Supplementary Figure 1 Nanog 0.1 0.2 0.3 0.4 0.5 NSC piPS iPS ES Relative expression 1 2 3 4 NSC piPS iPS ES pmx-c-myc pmx-Klf4 pmx-Oct4 pmx-Sox2 Relative expression C A

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Supplementary Figure 1. A. B C D. 10 6. 0.5. iPS. Nanog. pmx- c-myc. 4. 10 5. piPS. 0.4. pmx- Klf4. 10 4. pmx- Oct4. 3. Relative expression. Relative expression. 0.3. pmx- Sox2. Cell number. 10 3. 2. - PowerPoint PPT Presentation

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101

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1 2 3 4 5

iPSpiPS

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ber

Passage number

Supplementary Figure 1

Nanog

0.1

0.2

0.3

0.4

0.5

NSC piPS iPS ES

Rela

tive

expr

essi

on

1

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NSC piPS iPS ES

pmx-c-myc

pmx-Klf4

pmx-Oct4

pmx-Sox2

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tive

expr

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on

B C D

A

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Supplementary Figure 1

Mycn Arid3b

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