1. Respiratory System Ok

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    RESPIRATION SYSTEMIN HUMAN

    GASEOUS EXCHANGE RESPIRATORY SYSTEM

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    BASIC COMPETENCE3.4 Explaining the Relationshpbetween the structure,the

    function,and the process and alsodisorders/diseases that happen tohuman and animals respirationsystem (for example bird).

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    INDICATOR

    Explaining the function and structure ofhumans respiration system Explaining humans respiration

    mechanism.Differentiating the chest and stomachrespiration.Explaining the mechanism process of

    transfering Oxygen and carbondioxidefrom alveolus to blood capillary and viceversa.

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    OBJECTIVES

    AFTER LEARNING THIS CHAPTER,YOU WILL ABLE TO IDENTIFY,CONNECT AND EXPLAIN THESTRUCTURE, FUNCTION AND THEPROCESS OF RESPIRATORY SYSTEMIN HUMAN, ALSO IDENTIFY

    DISORDER THAT HAPPENS INHUMAN RESPIRATORY SYSTEM

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    HUMAN RESPIRATION SYSTEMA. Respiration organs.B. Breathing mechanism.C. Internal respiration.

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    Respiration is the process of air taking toget oxygen required for oxidation offoodstuff that happens in cell with its finalproduct is energyBreathing is taking of respiratory air fromfree air to enter into the lung anddischarge of waste gas from lung to freeair

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    AIR TAKING FOR EACH KIND OFORGANISM

    Inderectly : happens in organismthat already has particularrespiratory organex: HumanDerectly : happens in organism thatalready has not yet particularrespiratory organex: soil worm

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    The human respiratory system

    Figure 22.6A

    Nasalcavity

    Left lung

    Pharynx (Esophagus)

    Larynx

    Trachea

    Bronchus

    Bronchiole

    Diaphragm (Heart)

    Rightlung

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    In humans and other mammals, airenters through the nasal cavity

    It passes through the pharynx and

    larynx into the tracheaThe trachea forks to form two bronchiEach bronchus branches into numerousbronchioles

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    AIR IS TAKEN DOWN INTO THE LUNGS

    Air can enter the body through either the nose or mouth. The noseand the mouth are separated by the palate, so you can breathethrough your nose even when you are eating.

    Is is better to breathe through your nose, because the structure of the

    nose allows the air to become warm, moist, and filtered before it getsto the lungs. Inside the nose are some thin bones called turbinalbones which are covered with a thin layer of cells. Some of these cellsmake a liquid containing water and mucus which evaporates into theair in the nose and moistens it.

    1. The NOSE and MOUTH

    Other cells have very tiny hair-like projections called cilia. The cilia are always moving, and bacteria or particles of dust get trapped inthem and in the mucus. Cilia are found all along the trachea andbronchi, too. They waft the mucus, containing bacteria & dust, up to

    the back of the throat, so that it doesnt not block up the lungs .

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    The air then passes into the windpipe or trachea. At the top of the

    trachea, is a piece of cartilage called epiglottis . This closes thetrachea and stops food going down the trachea when you swallow.This is a reflex action, which happens automatically when a bolusof food touches the soft palate.

    2. The TRACHEA

    The air then passes into the windpipe or trachea. At the top of thetrachea, is a piece of cartilage called epiglottis . This closes thetrachea and stops food going down the trachea when you swallow.This is a reflex action, which happens automatically when a bolusof food touches the soft palate.

    Just below the epiglottis is the voice box or larynx. This containsthe vocal cords. The vocal cords can be tightened by muscles sothat they make sounds when air passes over them. The tracheahas rings of cartilage around it, which keep it open.

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    The trachea goes down through the neck and into the thorax. The

    thorax is the upper part of your body from the neck down to thebottom of the ribs and diaphragm. In the thorax, the tracheadivides into two. The two branches are called the right and the leftbronchi . One bronchus goes to each lung and then branches outinto many smaller tubes called bronchioles .

    3. The BRONCHI

    At the end of eachbronchiole are tiny air

    sacs or alveoli. This iswhere gaseousexchange takes place.

    4. The ALVEOLI

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    ALVEOLAR WALLS FORM THE RESPIRATORY SURFACEThe walls of the alveoli are respiratory surface. Tiny blood vessels,

    called capillaries, are closely wrapped around the outside of thealveoli. Oxygen diffuses across the walls of the alveoli into the blood.Carbon dioxide diffuses the other way.

    The walls of the alveoli have several features which make them anefficient gaseous exchange surface.

    They are very Thin

    Alveolar walls are only one cell thick. The

    capillary walls also only one cell thick. Anoxygen molecule only has to diffuse acrossthis small thickness to get into the blood.

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    The bronchioles end in clustersof tiny sacs called alveoli

    Alveoli form the respiratorysurface of the lungsOxygen diffuses

    through the thinwalls of thealveoli intothe blood

    Figure 22.6C

    Figure 22.6B

    Oxygen-richblood Oxygen-poor

    blood

    Alveoli

    Blood capillaries

    Bronchiole

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    Smoking causes lung cancer andcontributes to heart disease

    Smoking also causes emphysemaCigarette smokemakes alveoli

    brittle, causingthem to ruptureThis reduces thelungs capacity

    for gas exchange

    Figure 22.7A, B

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    Breathing is the alternation of inhalationand exhalation

    Breathing ventilates the lungs

    Figure 22.8A

    Rib cageexpands as

    rib musclescontract Airinhaled

    Lung

    Diaphragm

    INHALATIONDiaphragm contracts

    (moves down)

    EXHALATIONDiaphragm relaxes

    (moves up)

    Rib cagegets smalleras rib musclesrelax

    Airexhaled

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    Inhalation process in chest respiration

    Outer inter ribs contraction

    The volume of chest cavity increases

    Lungs becomes developing

    The pressure of chest cavity decreases

    The pressure of lungs decreases

    External air/O2 enter into pulmonary cavity

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    Lung total volume

    Respiratory air : air that enters or out thelung as the effect of ordinate respiration

    500 cc

    Complementary air : air that still can putinto the lung maximally after doing normalinspiration

    1500 cc

    Reservation air : air that still can be

    discharged maximally after doing normalexpiration

    1500 cc

    Residual air : air that still remain in thelung after doing max respiration

    1000 cc

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    Cavity vital : (500 + 1500 + 1500) cc = 3500 cc

    Volume total (3500 + 1000) cc = 4500 cc

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    THE RIBS & DIAPHRAGM MOVE DURING BREATHING

    To make air move in and out of the lungs, you must keep changingthe volume of your thorax. First, you make it large so that air issucked in. then, you make it smaller again so that air is squeezedout. This is called breathing or ventilation.

    There are 2 sets of muscles which help you to breathe. One set isin between the ribs. This set is called intercostal muscles made upof the external and internal intercostal muscles. The other set is inthe diaphragm. The diaphragm is a large sheet of muscle andelastic tissue which stretches across your body, underneath thelung and hearth.

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    BREATHING IN IS CALLEDINSPIRATION

    When breathing in, the muscles of the diaphragm contract. Thispulls the diaphragm downwards, which increases the volume in thethorax. At the same time, the external intercostal muscles contact.This pulls the ribs the ribs cage upwards and outwards. Together,these movements increase the volume of the thorax.

    As the volume of the thorax increases, the pressure inside it fallsbelow atmospheric pressure. Extra space has been made andsomething must come in to fill it up. Air therefore rushes in alongthe trachea and bronchi into the lungs.

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    BREATHING OUT IS CALLEDEXPIRATION

    When breathing out, the muscles of the diaphragm relax. Thediaphragm springs back up onto its domed space because it ismade of elastic tissue. This decreases the volume in the thorax.The external intercostal muscles also relax. The rib cage dropsdown again into its normal position. This also decreases the

    volume of the thorax.As the volume of the thorax decreases, the pressure inside itincreases. Air is squeezed out through the trachea into the noseand mouth, and on out of the body.

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    Vital capacity is the maximum volume ofair we can inhale and exhale

    But our lungs hold more than this amount

    The alveoli do not completely collapseA residual volume of dead air remains in thelungs after exhalation

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    Breathing control centers are located in thepons and medulla of the brain

    These automatic controls keep breathing in

    tune with body needs

    Breathing is automatically controlled

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    During exercise, the CO 2 level in the bloodrises, lowering the blood pH

    This triggersa cascade ofevents

    Figure 22.9

    Brain

    Cerebrospinal fluid

    BREATHING CONTROLCENTERS stimulated by:

    CO 2 increase / pH decreasein blood

    Nerve signalindicating lowO 2 level

    O 2 sensorin artery

    Pons

    Medulla

    Nerve signalstriggercontractionof muscles

    Diaphragm

    Rib muscles

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    Figure 22.1

    1 Breathing

    2 Transportof gases bythe circulatorysystem

    3 Servicing ofcells withinthe bodytissues

    Lung

    O 2

    CO 2

    Circulatorysystem

    Capillary

    Cell

    CO 2

    O 2

    Mitochondria

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    Gas exchangein the body

    Figure 22.10A

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    Hemoglobin is a protein in red blood cells

    It carries most of the oxygen in the blood

    Figure 22.10B

    Hemegroup

    Ironatom

    Polypeptide chain

    O 2 loadedin lungs

    O2 unloaded

    in tissues

    O2

    O2

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    Hemoglobin helps buffer the pH of bloodand carries some CO 2

    Hemoglobin helps transport CO 2 and buffer the blood

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    Most CO 2 in theblood combines withwater to formcarbonic acid

    The carbonic acidbreaks down to formH+ ions andbicarbonate ionsThese help buffer theblood

    Figure 22.11A

    TISSUE CELL

    CO 2 produced

    INTERSTITIALFLUID CO 2

    CO 2

    CO 2

    BLOODPLASMAWITHINCAPILLARY

    Capillarywall

    H2O

    H2CO 3Carbonic acid

    REDBLOODCELL

    HCO 3 + H+

    Hemoglobinpicks upCO 2 and H +

    Bicarbonate

    HCO 3

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    Most CO 2 is

    transported to thelungs in the form ofbicarbonate ions

    Figure 22.11B

    ALVEOLAR SPACE IN LUNG

    CO 2

    CO 2H2O

    H2CO 3

    HCO 3 + H+

    HemoglobinreleasesCO 2 and H +

    HCO 3

    CO 2

    CO 2

    C ti Th h f t h

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    A human fetusdepends onthe placentafor gasexchange

    Connection: The human fetus exchangesgases with the mothers bloodstream

    Figure 22.12

    Placenta, containingmaternal blood vesselsand fetal capillaries

    Umbilical cord,containing fetalblood vessels

    Amnioticfluid

    Uterus

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    A network of capillaries exchanges O 2 andCO 2 with maternal blood that carries gases

    to and from the mothers lungs

    At birth, increasing CO 2 in the fetal bloodstimulates the fetuss breathing controlcenters to initiate breathing

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    EXTERNAL RESPIRATION

    O2 carrying with Hb :Hb4 + 4 O2 4 HbO2 (Oksihemoglobin)

    Released CO2 from capilary (artery pulmonary)H+ + HCO3 - H2CO3 H2O + CO2O2 + HbCO2 HbO2 + CO2

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    INTERNAL RESPIRATION Released O2

    HbO2 Hb + O2 Carrying CO2

    CO2 + HbO2 HbCO2 + O2(Karbominohemoglobin)

    CO2 + H2O karbonat anhidrase H2CO3HCO3 - + H +

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    CELL RESPIRATION

    C6H12O6 + O2 ATP+ CO2 + H2O