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Biodesign at ASU

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Design Imperatives

• ASU Must Embrace its Cultural, Socioeconomic, and Physical Setting

• ASU Must Become a Force, and Not Only a Place

• ASU as Entrepreneur • Pasteur’s Principle • A Focus on the Individual • Intellectual Fusion • Social Embeddedness • Global Engagement

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bio.de.sign: the creative linkage of

fundamental science and technology

based solutions to confront specific

human challenges.

Arizona Biodesign Institute

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To advance innovations improving quality of life through

use-inspired, biosystems research and effective, multidisciplinary

partnerships.

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• Collaboration

• Communication

• Integration

• Use-inspired

• Translation

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Pasteur’s Quadrant

Research Inspired by a Quest for Fundamental

Understanding

Research is not Inspired by a

Quest for Fundamental

Understanding

Research not Inspired by Considerations of Use

Research Inspired by Considerations of Use

I.

IV. III.

II.Pure BasicResearch

Use InspiredBasic

Research

PurelyApplied

Research

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BiotechnologyNanotechnology

Information Technology

Biologics & Pharmaceuticals Neural Interface &

Rehabilitation Therapies Nano-scale

Biosystems & DevicesGenomics &

Bioinformatics

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Institute Director George Poste

Leading Scientist• DVM and Ph.D. Virology• > 350 publications• Fellow of the Royal Society• Honorary Doctorate in Science

CTO and President R&D SmithKline Beecham

• Brought 29 drugs to market• Introduced genomics as discovery tool

to pharmaceutical industry

Policy Expert• NAS working group on non-proliferation of Bioweapons• Chair DoD Task Force on Bioterrrorism• Honorary Doctorate in Law

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Research & Design Centers

• Focused on defined problems of major importance

• Networked to multiple departments, colleges, and external institutions

• Structured to be flexible and adaptive

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• Production of Vaccines from Applied Crop ScienceCharles Arntzen, Director

• Protein and Peptide PharmaceuticalsColleen Brophy, Director

Biologics and Pharmaceuticals

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Bio-Optical Nanotechnologies Neal Woodbury, Director

Single Molecule Biophysics Stuart Lindsay, Director

Applied NanoBioscience Frederic Zenhausern, Director

Nano-scale Biosystems and Devices

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Neural Interface and Brain Control Jiping He, Director

Rehabilitation Neuroscience/Rehabilitation Engineering James Abbas, Ranu Jung, Directors

Neural Interface and Rehabilitation Therapies

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• Evolutionary Functional Genomics Sudhir Kumar, Director

• Experimental Genomics Jeff Touchman, Director

Genomics and Bioinformatics

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Phase 1 - 170,000 sq. ft.

State-of-the-art: research only; for biosciences, IT, nanotech labs

Communication & Collaborative: open architecture, shared interdisciplinary labs

Flexible: reconfigurable project-based space

Serve as a Hub: prime location, access

Arizona Biodesign Institute

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Phase I - 170,000 sq. ft.

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Phase IPhase I Phase IIPhase II Phase IIIPhase III

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ASU School of Life Sciences

• Biology• Microbiology• Plant Biology• Clinical Laboratory Sciences Program• Molecular Biosciences/Biotechnology

Program

Expanding: 75-100 faculty over the next 5 years

Enhancing Intellectual Fusion: Reorganizing for agility and creating a more horizontally integrated structure

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ASU School of Life Sciences

Laboratories and Facilities• DNA Laboratory• Goldwater Environmental Laboratory• W.M. Keck BioImaging Laboratory• Electron Microscopy Facility• ASU Lichen Herbarium• Vascular Plant HerbariumResearch Support • Life Sciences Computer Support Cluster• Life Sciences Visualization LabOutreach • Ask a Biologist• Ecology Explorers

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NSF IGERT in Musculoskeletal and Neural Adaptation in Form and Function

• 13 co-investigators– BME, Physics, Anthropology, Exercise

Science, Math, Bio

– SSERC, PRISM, Institute of Human Origins

• In partnership with Barrows Neurological Institute, Good Samaritan Medical Center, Mayo Clinic, Scottsdale Medical Imaging

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NSF IGERT in Optical BioMolecular Devices

Bio-molecularDevices

BiomedicalTechnology

LightActivatedProcesses

MolecularMachines

NovelMaterials

MolecularElectronics

Invention and engineering of new materials, processes and devices

Biomimetics

Cellular and molecularbiology

Biology of light-mediatedprocesses

Light-interactivematerials

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• CAP LTER is one of only 2 urban sites in NSF’s network of 24 LTER sites

• 60 faculty members, 90 grad students, 15 postdocs, 67 under-grads, 85 K-12 teachers, and over 40 community partners are engaged in this research

• Original $4.2 million in funding has been leveraged to $18.5 million

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ASU Center for the Study of Law, Science & TechnologyExecutive Director: Gary Marchant, Ph.D.

• Oldest and largest academic center in the nation studying the law’s interaction with science and technology

• Established in 1984• 17 Faculty Fellows with expertise in law,

science and technology – focus on legal and policy issues relating to

genomic technologies, intellectual property, privacy, bioethics, GM foods, digital copyright, e-commerce, antitrust, environmental regulation, public health, forensic sciences, scientific evidence, nanotechnology, telecommunications, human behavior, and family law.

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Bioscience & Biotechnolog

y(301)

Nanoscience &

Technology(301)

Information Science &

Technology(301)

Manufacturing(301)

EnvironmentEarth / Space

Science

Social Science &

Public PolicyHumanities Arts

Education(301)

Arizona Biodesign Institute

Rapidly Urbanizing Regions /

Environments

International Digital Library

Arts, Media & Engineering

(AME)CRESMET

School of Life Sciences

Institute for Comp/Info

S&EAstrobiology

Health and Disability

Policy

Competitive Grants

Program

Bio-engineering Wireless Nanotechnology Center (WINTECH)

Bio-geochemistry

American Indian Health

Initiative

Law, Science & Technology

Stress/Neuro-

endrocrine

Nano-electronics

Embedded Systems (CEINT)

Supply Chain Integration

PlanetaryMissions

Prevention Intervention

ITAC

Homeland Security InstituteMorrison Institute

Religion and Conflict

Museum Project

Animal Care CSSER / CSSS

Super-computer

Research Investment Strategy

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Technopolis

• Entrepreneurial education• Product development assistance• Business infrastructure development and

management assistance• Proof-of-concept capital formation• Revenue development assistance

Mission: Encourage innovation in Greater Phoenix by providing local entrepreneurs with the entrepreneurial education and hands-on business development assistance necessary to convert their ideas into commercially viable businesses.

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Arizona Technology Enterprises

Arizona Technology Enterprises,

LLC

Utilize Industry specific

consultants & brokers

General solicitations to market players

Create University based start-ups

Leverage clients of VC funds, investment banks & lawfirms

Leverage Industry relationships

Contingency-based

Outlicensingfirms

Technology bundling with

other institutions

Partner with Corporate spinouts

Utilize Web-based IP Exchanges

(Yetz.com)

Utilize Universitywebsite