Upload
abhijit-sanjeev
View
216
Download
0
Embed Size (px)
Citation preview
8/13/2019 05_N007_16183
1/19
RAJIV GANDHI UNIVERSITY OF HEALTH
SCIENCES BANGALORE, KARNATAKA
PROFORMA FOR REGISTRATION OF SUBJECTSFOR DISSERTATION
1 Name of the Candidates andAddress
Mr. LALHMINGMAWIA
THANGLUAH
1styear M.Sc. (Nursing)
Florence College of Nursing
Bangalore43
2 Name of the institution Florence College of Nursing
3 Course of study and Subject M.Sc. (Nursing)
Community Health Nursing
4 Date of admission to the Course 28thOctober 2009
5 Title of the Topic Effectiveness of a video
assisted teaching programme
on knowledge regarding
leptospirosis among farmers in
selected rural areas,
Bangalore.
8/13/2019 05_N007_16183
2/19
6. BRIEF RESUME OF INTENDED WORK:
INTRODUCTION:
Leptospirosis is severe and contagious bacterial infection. It is caused by
exposure to several types of the Leptospira bacteria, which can be found in fresh
water that has been contaminated by animal urine. The alternative names of
Leptospirosis are Weil disease, Ictehemorrhagic fever, Swine herds disease, Rice
field fever, cane-cutter fever, Swamp fever, Mud fever, heamorrhagic jaundice,
Stuttgart disease, Canicola fever and, rat fever and farmers disease in india.1
Leptospirosis is essentially animal infection by Serotypes of Leptospira
(spirochetes) and transmitted to man under certain environmental conditions. At
present, 23 sero groups and 200 serovars have been recognized from various part of
the world. It has high prevalence in warm humid tropical countries. The disease
manifestations are many and varied, ranging in severity from a mild febrile illness to
severe and sometimes fatal disease.2
The some sources of human infection are rats, dogs, cats, livestock and wild
animal. Once infected, animal excrete spirochetes in the urine for an extended period
of time. Leptospire survival outside the human host is dependent on the moisture
content, temperature and pH of the soil and water into which they are shed. The
majority of the human cases worldwide result from occupational exposure to rat
contaminated water or soil. Occupational groups with a high incidence of
Leptospirosis include agriculture workers, person who live or work in rat infested
environment, individuals involved in animal and husbandry or veterinary medicine,
and laboratory workers.3
8/13/2019 05_N007_16183
3/19
Leptospirosis is a zoonotic spirochiteal disease of global importance. The
disease continues to have a major impact on people living at urban and rural areas in
developing countries. Leptospirosis is underreported due to lack of clinical suspicion
and barriers to diagnostic capacity. General physicians often lack familiarity with
the broad clinical presentation of leptospirosis. Most commonly, human infection
with pathogenic leptospira results in asymptomatic seroconversation and less
commonly in a symptomatic illness. When symptomatic, leptospirosis most often
manifests as an undifferentiated febrile illness. In endemic areas, factors such as lack
of sanitary conditions, mud flooring, together with rainy seasons and flooding
catastrophes contribute to periodic outbreaks.4
India is a developing country, about 72-74% of the people live in rural areas.
The main source of income is agriculture; several millions of them are either
marginal farmers or work on hired labour and struggle for bare necessities of life. It
is said that nearly 11% of the total wild animal population is in India. It is usually
observed that, animals are house under the same roof as human being. Therefore all
possibilities exist for the various diseases to be transmitted by the animals to man.5
6.1 NEED FOR STUDY:
According to WHO, the incidences ranges of leptospirosis from
approximately 0.1 1 per 1,00,000 per year in temperate climates to 10 100 per
1,00,000 in the humid tropics. During out breaks and high exposure risk groups,
disease incidence may reach over 1001,00,000. The case-fatality rates in different
parts of the world have been reported to range from
8/13/2019 05_N007_16183
4/19
Based on National Epidemiological Surveillance of Infectious diseases
(NESID), the report on prevalence of leptospirosis showed that the estimated
sources of infection of the 93 notified cases were- Farm workers (31 cases); Leisure
activities and labour at the rivers (23 cases); contact with fresh water of other than
rivers labour(16 cases); direct and indirect contact with rodents(17 cases); unknown
(6 cases). Therefore, the sources of infection are occupational or recreational
exposure in environment contaminated with urine of carrier animals, and occupation
having a chance of direct contact with urine or blood of infected animals.7
A study was conducted on prevalence of leptospirosis in Kerala, about 37
cases were selected by using simple stratified sampling techniques. The studies
showed that people belonging to 30-45 age group were affected more(51.3%), both
males and females. There was not a single case in the 015 age groups, with 10.8%
belonging to 60 plus age group. As in the other studies, Male cases dominated- of
the total, 68% were male and 32% were female. This is despite the fact that more
than 50% of those affected are engaged in agriculture work, identified as the major
routes of transmission.8
A study was conducted on prevalence of leptospirosis among the Pyrexia
Unknown Origin(PUO) cases in a Tertiary care Hospital of Kashmir Valley, about
72 in-patients cases were enrolled as participants. All the samples are tested by
Lepto Dipstick. The study showed that of the 72 studied cases, 43 were male and 29
female, predominantly in the age group 21 40 years. Results showed that 1 of 15
urban(6.66%) and 14 of the 57 rural (24.56%) patients were positive for leptospira
8/13/2019 05_N007_16183
5/19
antibodies respectively. About 13 of the 15 patients who tested positive (86.66%)
gave a definite history of animal contact. 9
Human leptospirosis is prevalent in many states in India, sporadically or as
outbreaks, especially during rainy seasons. It affects predominantly male adults who
work in agriculture, causing severe morbidity and mortality with serious economic
repercussions to families and to society. Yet, there is no systematic leptospirosis
prevention and control programme in the country and not included under the
national health policy. Thus, Personal protection and public health control are
relevant in this disease.10
Leptospirosis is a potentially serious but treatable disease. More than half of
the total population lives in rural areas and their lives depend mainly on agriculture.
Chances of exposure to the risk factors is high due to lack of knowledge about the
illness, poor working condition and inadequate housing. Since Leptosporosis is a
public health threat and hence, it is necessary to increase awareness and knowledge
on leptospirosis among farmers in the rural areas. So, the researcher found it relevant
to evaluate the effectiveness of video assisted teaching programme on Leptospirosis
6.2 Review of Literature:
The review of literature is an organized critique of the important scholarity
literature that supports a study and a key step in the research process. The overall
purpose of review of literature in the research study is to present a strong knowledge
base for the conduct of the research project. The main goal of a literature review is
8/13/2019 05_N007_16183
6/19
to develop the foundation of a sound study, but it also is used for other scholarity,
educational and clinical practice activities. 11
A study on the prevalence of Leptospirosis among the 227 risks groups was
conducted in and around Nagpur. The test group included 55 patients of pyrexia
unknown origin(PUO), 42 veterinary workers, 38 Hepatitis patients and 25 village
farmers. The control group comprised of 27 Syphilis and 40 healthy groups. Test
was done either by IgM ELISA and by Microscopic agglutination test (MAT). Out
of 160 patients of the test group 56(35.0%) were positive for Leptospiral antibodies.
Of these, the positivity was 18(32.73%) amongst Pyrexia unknown origin (PUO), 15
(35.71%) of farm workers, 15(39.47%) of hepatitis and 8(32.0%) of farmers.
Leptospirosis antibodies was not detected in any of the control groups. Out of 56
leptospira cases, 39(69.64%) has a history of animal contacts. The result shows that
PUO patients with jaundice especially in presence of the history of animal contact
should be suspected more.12
A descriptive study was conducted to assess prevalence of leptospirosis
outbreak among the 942 clinically suspected cases of leptspirosis admitted into
Lokmanaya Tilak Municipal General Hospital, Mumbai. Serum samples were tested
by Tek Dri-Dot/Leptocheck. Among 165 positive serra by these test were sent to
IRR, Mumbai for detection of leptospira IgM antibodies by ELISA (panbio). About
87 positive sera were also sent to BJ Medical College, Pune for Microscopy
Agglutination Test(MAT) for serovar identification. Seropositivity with Leptocheck
Tek Dri-Dot/Leptocheck was 34.3 %, IgM ELISA positivity was 69.1% and MAT
positivity was 29.9%. Considering at least two of the above three serological test
8/13/2019 05_N007_16183
7/19
positive, 127 cases could be diagnosed and only 89.8% of them could be diagnosed
by ELISA and rapid test. The study therefore, concluded that alongwith rapid
serological test, IgM ELISA should be routinely done for laboratory diagnosis of
leptospirosis.13
A descriptive study on prevalence of leptospirosis in Andhra Pradesh was
done among 86 suspected cases. Of these, 49(56.97%) serum samples were found
positive for leptospirosis by DGM test and IgM antibodies. The mean age of the
positive cases were 42.7 years. All the 49 positive cases had fever (100%), Myalgia
(42.9%), stiffness of the calf muscles (55.1%) and headache (32.6%) and
conjunctival suffusion (2.04%). The studies indicated that transmission was from
contaminated stagnant water. The barefooted villagers living with livestock and
rodents were significantly associated with seropositivity.14
A descriptive study on prevalence of human leptospirosis among hospital
cases of erode, South India was performed by using isolation and serological test
such as the microscopic agglutination test(MAT) and IgM-based enzyme-linked
immunosorbent assay. Out of 29 patients, 26(89.7%) were diagnosed as having
leptospiral infection. Case fatality rate was 3.4%. The age of patients ranged
between 10-70 years and median age was 42.5 years. The study results showed that
that 93.1% of the patients were male and all patients, excepts one were agriculture
labourer. This study concluded that leptospirosis is a potential health hazard of
Agriculture Workers.15
8/13/2019 05_N007_16183
8/19
A serological survey of Leptospira infection in Nepal by one-point
microcapsule agglutination(MCA) test was done among 200 patients(104 males and
96 females) attending out patient department. Among 200 serum samples taken-
32%(64 out of 200) of the subjects possessed antibodies to leptospira. The
Leptospira-antibody prevalence was dependent of gender and geographical
areas(P>0.05). The antibody prevalence in different age and ethnic groups ranged
from 27.5 34.0% and 28.5 40.0% respectively. The difference was not
significant (P>0.05%). The reports of the results suggested that Leptospira infections
are uniformly distributed in different age, sex, ethnics and geographical areas. 16
A study to investigate the risk factors for mortality in patients with
Leptispirosis during an epidemic outbreak in northern Kerala was done through
clinical examination, laboratory investigation and leptospira serology -Microscopic
agglutination test(MAT). Of the 468 cases suspected to have leptospirosis, serology
could be done in 360 patients. Of these, MAT was positive in 282 patients. Case
fatality rate was 6.03%.Out of 282 seropositive cases 58.9 % were men and 29%
were engaged in agriculture occupations. The result shows that majority of the
patient (62.9%) had either fissures or other wounds on the feet and no patient had
direct occupational exposure to animal.17
A leptospirosis clinical-epidemiology study was made in humans and
reservoirs. Interviews and serological analyses were made on 400 persons from an
open population; 439 probable cases of leptospirosis and 1060 animal
reservoirs(cows, pigs, dogs, rats and opossums). IgM Leptospira Dipstick and
Microscopic agglutination Test(MAT) was used to detect human antibodies to
8/13/2019 05_N007_16183
9/19
leptospiras and serovars respectively. Leptospirosis in humans was 2.2/1,00,000
inhab. In 1998, 0.7/1,00,000 in 1999 and 0.9/1,00,000 in 2000. Overall
seroprevalence was 14.2%, relatively unchanged from seroprevalences observed 20
years ago highest seroposivity was found in people over 56 years of age,
predominating males over females.Leptospirosis cases were more frequent in rural
areas. Contacts with rodents and natural water sources were significant factors
(p
8/13/2019 05_N007_16183
10/19
recognised. Barriers to addressing this problem have been the lack of an adequate
diagnostic test and effective control measures. China and Brazil countries have
completed the sequence of the leptospira genome. Together with new genetics tools
and proteomics, new insights have been made into the biology of leptospira and the
mechanisms used to adapt to host and external environments. Surface protein
exposed proteins and putative virulence determinants have been identified which
may serve as sub-unit vaccine candidates. Future challenges will be to translate these
advances into public health measure for developing countries. 20
6.3 STATEMENT OF PROBLEM
A study to evaluate the effectiveness of Video Assisted Teaching Programme
on knowledge regarding Leptospirosis among farmers in selected rural areas,
Bangalore.
6.4 OBJECTIVE OF THE STUDYThe objectives are:-
to assess the knowledge of farmers regarding Leptospirosis. to organise a video assisted teaching programme on leptospirosis. to evaluate the effectiveness of video assisted teaching programme on
leptospirosis.
to find out the association between knowledge of farmers regardingleptospirosis with socio-selected demographic variables.
8/13/2019 05_N007_16183
11/19
6.5 HYPOTHESES
H1- The mean post-test knowledge scores of the farmers regarding leptospira
infection will be significantly higher than the mean pre-test knowledge scores.
H2- There will be significant association between the mean pre-test knowledge
scores and the selected socio-demographic variable.
6.6 OPERATIONAL DEFINITION OF TERMS
In this study it refers to:-
Evaluate:
Finding the values of video assisted teaching programme on knowledge of
farmer regarding leptospirosis.
Effectiveness:
Determine the extent to which the video assisted teaching programme has
achieved desire effect as measure in terms of significant gain in the post-test
knowledge scores of farmers and graded as adequate, moderately adequate and
inadequate knowledge.
Video assisted teaching programme:
Systematically developed audio-visual aids designed for selected group of
farmers to provide information about leptospirosis such as, causes, risk factors,
pathology, clinical manifestation, diagnosis and treatment.
Knowledge:
The level of understanding of the farmers regarding leptospiral infection in
terms of their gain in the knowledge scores as measured by the correct responses to
the items in the tool.
8/13/2019 05_N007_16183
12/19
Leptospirosis:
Any infectious disease due to a serotype of Leptospira, manifested by
lymphocytic meningitis, hepatitis, and nephritis, separately or in combination, and
varying in severity from a mild carrier state to fatal disease.
Farmers:
Persons who owns or manages farm (age between 2060 yrs)
6.7 ASSUMPTION
The study is based on the following assumptions:-
Farmers from the rural areas are more prone to get leptospira infection. Video assisted teaching programme may be more effective to impart the
knowledge for illiterate farmers.
Explaining about the study may help to get co-operation.
6.8 DELIMITATIONS
The study delimited to farmers:-
Males and females age between 20 - 60yrs. Who are residing at selected rural areas. Who speaks Kannadda.
7 MATERIALS AND METHODS
7.1 Sources of Data
Farmers in a selected rural areas.
8/13/2019 05_N007_16183
13/19
7.2 METHOD OF DATA COLLECTION
Research Method : Pre-experimental method.
Research design : One group pre-test and post-test design.
Sampling Technique : Purposive sampling techniques.
Sample Size : 60 farmers.
Setting of the Study : Dodda Gubbi Village, Bangalore District.
7. 2.1 CRITERIA FOR SELECTION OF SAMPLE
INCLUSION CRITERIA
This study includes farmers who are:-
1. available at the time of study2. willing to participate in the study3. able to speak Kannada.
EXCLUSION CRITERIA
This study includes farmers who are:-
1. below 20 and above 60 years of age.2. having communication problems.
7. 2.2 DATA COLLECTION
Data collection tool will be a structure interview schedule, which consists of
demographic profile and questions to assess the knowledge of the subjects regarding
leptospirosis. A video assisted teaching programme will be prepared regarding
leptospiral infection focusing on aspect such as causes, risk factor, pathology,
clinical manifestation, diagnosis and treatment.
8/13/2019 05_N007_16183
14/19
Content validity of the tool will be ascertained with the help of guide and
experts in the field of Community Medicine and Nursing.
Reliability of the tools will be established by split half method. The tentative
period for data collection will be December 2010.
7. 2.3 DATA ANALYSIS METHOD
Data will be analyzed by using descriptive and inferential statistics.
Descriptive statistical analysis such as mean, median, standard deviation and
percentages distribution will be done. Inferential statistics such as t test will be
done to find out significance difference between the pre and post-test knowledge
scores and Chi-square test will be done to find out be significant association between
knowledge scores and the demographic variables.
7.3 DOES THE STUDY REQUIRE ANY INVESTIGATION OR
INTERVENTION TO BE CONUCTED ON PATIENTS OR OTHER HUMAN
OR ANIMALS ?
No.
7.4 HAS ETHICAL CLEARANCE BEEN OBTAINED ?
Yes;
Administrative permission will be obtained from the concerned authority. Confidentially and anonymity of the subjects will be maintained.
8/13/2019 05_N007_16183
15/19
8. LIST OF REFERENCE:
1. Goldman L, Ausiello D, Leptosiposis. Cecil medicine. 23rdeds. Philadelphia,Pa: Saunders Elsevier; 2007, Chapter 344.
2. Park K, Parks text book of preventive and social medicine. 19th eds. 2007,M/s Banarsidas Banot, jobalpur. P-243.
3. Berhman E. Richard, Kliegman M. Robert, Jenson B. Hal, Nelson textbookof pediatrics. 16theds. 2000, W.B. Saunders Company, Philadelphia, chapter
217, P-908.
4. Cachay ER, Vinetz Jim, A global research agenda for leptospirosis. JPostgard Med. 2005; 51:174-8.
5. Ghulani KK, Community health nursing. 1st ed. 2008, Kumar Publishinghouse, N. Delhi, P-290.
6. Human Leptospirosis: Guidance for diagnosis, surveillance and control.WHO Library Cataloguing in publication data, Annexure-I, 2003.
7. IASR, Leptospirosis in Japan, November 2003 - 2007. Vol. 29: No. 1(No.355).
8/13/2019 05_N007_16183
16/19
8. George Mathew, Socio-economic and cultural dimensions and Healthseeking behaviour for Leptospirosis: a case study of Kerala. 2007; 9;381-
398.
9. Shaheen Rubeena, Shah Azra, Prevalence of Leptospirosis among the PUOcases in tertiary care hospital of kashmir valley. Vol. 3, No. 5(2006-11
2006-12).
10.John TJ, The prevention and control of human leptospirosis. J postgrad Med2005; 51:205-9.
11.Lobiondo-Wood Geri, Haber Judith, Nursing research. 6th ed. MOSBYElsavier, Missouri, P-78.
12.Angnani R, Pathak AA, Mishra M, Prevalence of leptospirosis in various riskgroups. Indian journal of Medical Microbiology, (2003) 21(4): 271-273.
13.Mathur M, De A, Turbadkar D, Leptospirosis outbreak in 2005: LTMG,hospital experience. Indian J Med. Microbiol. 2009 Apr-jun; 27(2): 153-5.
14.Shohan L, Shyamlal B, Kum TS, Malini M, Rav K etal, Studies onleptospirosis outbreak in peddamandem mandal of chittoor district, Andhra
Pradesh. J Commun. Dis 2008 June:40(2) 127-32.
8/13/2019 05_N007_16183
17/19
15.Natarajaseenivasa Kalimuthusamy, Prabu Nagarajan, SelvanyakiKhrisnamamy, Raja Sudalaimuthu Savalaikarankulam Suresh, Ratnam
Sivalingam, Human leptospirosis in erode, south India; serology, isolation
and characterization of the isolates by randomly amplified polymorphic
DNA(RAPD) fingerprinting. Jpn. J. infect. Dis., 57,193-197,2004.
16.Rai Kumar Shiba, Shibata Hiroshi, Sumi Katsumi, Uga shoji, Ono Kazuo,Strestha Govinda Hari etal., Serological study of Leptospira infection in
Nepal by one-point MCA methods. J infect Dis Antimicrob Agents 2000;
17:29-32.
17.Pappachan MJ, Mathew Sheela, Aravidan KP, Khader Aysha, Bhargaran PV,Kareem Abdul MM, etal., Risk factors for mortality in patients with
leptospirosis during an epidemic in northern Kerala. National Medical
Journal India 2004;17:240-3.
18.Vado-Solis Ignacio, Cardenas-Murrufo Maria F, Jimenez-Delgadillo Bertha,Alzina-Lopez Alejandro, Laviada-Molina Hugo, Suarez-Solis Victor etal,
Clinical epdemiological study of leptospirosis in humans and reservoirs in
Yucatan, Mexico. Rev. inst. Med. Trop. S. Paulo, 44(6): 335-340, 2002.
19.Ghouse and Ali Mohamed M.G. Leptospirosis: challenges for doctors. TheHindu, Online edition of Indias National Newspaper. Wednesday, Aug, 17,
2005. Chennai, Tamil Nadu. http://www.hindu.com/2005/08/17/stories
/2005081714300500. htm
8/13/2019 05_N007_16183
18/19
20.Mcbride AJ, Athanazio DA, Reis MG, Ko Al, Leptospirosis. Goncalo MonizResearch Centre, Oswaldo Cruz Foundation, Brazil. Curr Opin Infect Dis.
2005 Oct;18(5):376-86.
ELECTRONIC SOURCES
1. www.googles.com2. www.pubmed.com3. Indian Medical Association
8/13/2019 05_N007_16183
19/19