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    PHARMACY HISTORY AND BASIC KNOWLEDGE IN PHARMACY

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    Contents

    1. Simple Choice .............................................................................................................................2

    2. Multiple Choice...........................................................................................................................6

    3. Pairing .......................................................................................................................................114. Relation analysis .......................................................................................................................14

    5. Answer key................................................................................................................................19

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    1. Simple Choice

    1. Which of the following great henlers systematized drugs

    A) Hygiene

    B) Aristoteles

    C) Galenus

    D) Asklepios

    E) Celsus

    2. The ancient Jewish pharmacists

    A) prepared some medicines according to prescriptions

    B) dissected

    C) cured through the use of astrologyD) did not trade in drugs

    E) compiled their knowledge in a pharmacopoeia

    3. Who carried out pharmaceutical activity in Egypt

    A) The nobility

    B) Clerical physicians

    C) Foreign Slaves

    D) Clerks

    E) Barbers

    4. What is the main point of the Hippocratic oath

    A) It defines the activity of physicians

    B) It ensures rights of the patients

    C) It prescribes compulsory secrecy

    D) It prohibits physicians from receiving material rewards

    E) It allows euthanasia

    5. What is the first surviving written record of Hungarian Pharmacy

    A) De medicina

    B) Pray Codex

    C) Aacheni Statutum

    D) Vademecum Hungarica

    E) Norma Pauperum

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    6. What is drug information

    A) Information provided to the specialists to facilitate optimum drug therapy and

    rational drug ordering.

    B) Information on the active ingredients of drugs

    C) Information concerning effective drug therapy and rational drug orderingD) Information on the fate of drugs in the human body

    E) One part of the subject pharmacology

    7. What is the essence of health education

    A) Prevention activity extending to the entire population

    B) Promotion activity in health care

    C) Public behaviour promoting the keeping of public health rules

    D) The exchange of information among the health care professionals

    E) Activity promoting the preservation or recovery of health. In the case of chronicdisease, it ensures the best recovery

    8. Who is a quack

    A) Someone who treats people with the method of folk-medicine

    B) Someone who gives first aid

    C) Someone who performs medical activity without medical qualifications

    D) Someone who performs medical practice under professional control before being

    awarded a medical diploma

    E) Someone who uses the methods of alternative therapy

    9. A preparation has a therapeutic effect if it

    A. Causes healing

    B. Contains combined active ingredients

    C. Does not have pathological activity

    D. Is a preparation containing only active ingredients of plant origin

    E. Contains ingredients with favourable biological activity of natural origin

    10. What is drug ordering

    A) The acquisition of drugs

    B) The distribution of drugs

    C) The medical prescription of drug usage

    D) The preparation of drugs on request

    E) The usage of a drug for an intended purpose

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    11. Which of the following answers is correct

    A) The currently used medical terminology originates from Babylonians

    B) To solve the lack of physicians Julius Caesar granted Roman civic rights to foreign

    professionals

    C) Panacea is stated to have treated in snake formD) There were already physicians and pharmacists in prehistory

    E) The Chinese long ago described the current mechanism of acupuncture

    12. What did incubation mean in ancient times

    A) The anaesthetisation of patients

    B) A special step in mummification

    C) The placing of an acupuncture needle in the body

    D) A technical expression connected with Greek gynaecology

    E) The treatment of patients while they were sleeping

    13. What is an Ispotal?

    A) The part of a health care house where the pharmacy functioned

    B) The name of a medical herb garden

    C) The name of the first hospital mentioned in the Funeral Oration

    D) A room built for patients by a monastic order

    E) The part of alchemy from which the pharmaceutical chemistry developed

    14. Which of the following statements is incorrect

    A) The first information about the first city doctors originates from Paris in the

    13th

    century

    B) Vatican documents state that the first Pharmacy in Hungary was built in Pozsony in

    1310

    C) Public Bath already existed in the era of King Stephan the First

    D) The importance of the foundation of public health institutions was recognised only

    in 19th

    century

    E) The first Hungarian Pharmacopoeia was published in 1871

    15. The most important element of the Law XII. of 1876 was that

    A) it did not relate only to the cities

    B) the pharmacy was recognised as a public health institution

    C) university education was prescribed

    D) the text of the pharmaceutical oath was given

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    16. The forerunner of the Formulae Normales was

    A) Decretum Medicinales

    B) 3rd

    of the Pharmacopoeia

    C) Norma Pauperum

    D) Medical CabinetE) Austrian Pharmacopoeia

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    2. Mult iple Choice

    17. Choose the most characteristic statements relating to the activity of Galenus

    1. He performed dissections

    2. Individual drug ordering originated from him

    3. He was involved in alchemy

    4. He introduced accurate drug preparation, prescriptions in order to achieve a

    standard effect

    5. He did not know the symptoms of inflammation

    18. Choose the correct answer relating to the ownership of pharmacies in Hungary in the

    19th

    century

    1. Public

    2. Personal ownership

    3. Military

    4. Real law

    5. All at the above

    19. Choose the correct answer relating to the Buda Law-Book

    1. It wanted to stop the sale of common goods in Pharmacies

    2. It did not regulate Sunday and holiday opening hours

    3. It did not order the control of adherence to the law

    4. It was published in 1240

    5. Was he first Hungarian city law concerning pharmacy

    20. Choose the correct answer relating to the law proclaimed by King Ferdinand the Third

    1. The law is known as Ordo Politiae

    2. It was the first law connected with health care

    3. It prescribed the education of pharmacists

    4. It dealt with Pharmacy in general5. It dealt with many questions of Pharmacy in details

    21. Which is the correct answer concerning the effective dose

    1. It is the clinically effective quantity

    2. It is the highest quantity which does not cause harm

    3. Its Latin name is the doses lethalis

    4. It is essentially the official dose usual in the Pharmacopoeia

    5. At larger doses it is lethal

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    22. Choose the correct answer relating to the ATC code of drugs

    1. The code systematizes the drugs from anatomical and pharmacological aspects

    2. The code shows which drugs can be ordered with insurance support

    3. The code shows which pharmaceutical company prepared the drug

    4. The code systematizes drugs from application aspects5. The code gives a listing relating to origin of drugs

    23. Choose the correct answer relating to the health care order of Maria Theresia

    1. The name of the order was Generale Normativa Re Sanitatisa

    2. The order did not require a diploma for pharmaceutical practice

    3. The order regulated the functioning of doctors

    4. The order was published in 1670

    5. The order prescribed a medical home pharmacy

    24. What is the Officina

    1. The room where drugs are given out

    2. The camera materialis

    3. The room where drugs supplied to the pharmacy are received

    4. A room which is suitable if it has artificial lighting

    5. The room for drug manufacturing

    25. What is the "inscription"

    1. The signature of the doctor on the prescription

    2. The heading on the prescription form

    3. It is only one word: Rp.

    4. It contains the name, the address and the age of the patients

    5. It is the doctors instructions to the pharmacist concerning the preparation of the

    drugs

    26. What is the "invocation"

    1. It is an instruction consisting of one word: Rp., i.e. Take

    2. A document of pharmacist relating to the preparation of the drug3. The place for the seal of the doctor

    4. The name of prescribed drug

    5. Instruction for the drug dosage

    27. What is the Formulae Normales

    1. A collection of prescriptions relating to all drug forms

    2. A collection of standard prescriptions

    3. A publication which exists in medical, veterinarian and pharmaceutical editions

    4. A publication which does not give the possibility to choose the drug preparationtechnology

    5. The medical version of Formulae Normales gives prescriptions in alphabetical order

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    28. What is the Hungarian Pharmacopoeia

    1. A publication whose edition VII has been valid since 1986

    2. A publication for the registration and standardization of drugs

    3. Ph. Hg. VII. has 3 volumes

    4. A publication containing the characteristic parameters of drugs5. A publication defining the usage of drugs

    29. The task of the special field of pharmaceutical history is

    1. to acquire the new data

    2. to replace existing data

    3. to list data

    4. to nurture the traditions of pharmacy

    5. to reveal connections

    30. Which are the ancillary sciences of pharmacy

    1. Methodology

    2. Statistics

    3. Archaeology

    4. Linguistics

    5. Balneology

    31. Which treatment methods were used by the Assyrians

    1. Cold water cure

    2. Administration of humoral materials

    3. Application of ear drops

    4. Acupuncture

    5. Massage

    32. Which of the following can be read about in the books known as the Vedas

    1. Mummification

    2. Drug preparation

    3. Ethics of treatment4. Poison and antidotes

    5. Homeopathy

    33. Which of the following was used successfully use in medical treatment by the Chinese

    1. Diet

    2. Narcotics and analgesics

    3. Health gymnastics

    4. Work therapy

    5. Venesection

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    34. What were the main results of the activities of Galenus

    1. Mapping of the blood circulation

    2. The first acupuncture atlas

    3. Introduction of the correct procedures ensuring a standard drug effect

    4. The publication of massage methods5. He did not introduce new drugs

    35. What kind of pharmacies existed during Hungarian history

    1. Private pharmacies

    2. Domanial pharmacies

    3. Monastic pharmacies

    4. Medical pharmacies

    5. Travelling pharmacies

    36. What are the goals of health care regulation

    1. To help health care research

    2. To ensure the protection of the health of the society

    3. To prevent the spread of epidemics

    4. To ensure state control

    5. To ensure the building of pharmacies

    37. What does the pharmaceutical oath extend to

    1. Discretion

    2. Diagnostics

    3. Openness

    4. Tolerance

    5. Protection of health, and promotion of patient recovery

    38. Which of the following doses are given in the Pharmacopoeia

    1. The recovery dose

    2. The usual dose

    3. The toxic dose4. The greatest dose

    5. The lethal dose

    39. Which are the aspects according to which drugs are classified

    1. The area of usage

    2. The time up to the effect

    3. The place of manufacture

    4. The frequency of usage

    5. The time of usage

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    40. Which parts belong to a Pharmacy

    1. A laboratory

    2. A roof space

    3. A chemical laboratory

    4. A part for making tablets5. A room for drug dispensing

    41. Beside the registration of drugs, which of the following is given by the Ph. Hg. VII.

    1. The method of supply

    2. The prescription of quality requirements

    3. The prices of drugs

    4. The characteristic constants

    5. The side-effects of drugs

    42. Which drugs are listed in the books known as the Vedas

    1. Eye-water

    2. Capsules

    3. Powders

    4. Nasal drops

    5. Tablets

    43. Which were the possibilities for the ownership of pharmacies in the 19th

    century

    1. State ownership

    2. Real ownership

    3. Personal ownership

    4. Hiring

    5. Private ownership

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    3. Pairing

    44. Pair the letters and the numbers

    A. The most important activities of pharmacists

    B. The independent activities of assistants

    1. Drug preparation

    2. Drug dispensing

    3. Store handling

    4. Filling of drugs

    5. Part procedures of drug preparation

    6. Drug analysis

    7. Dispensing of drug products

    45. Pair the letters and the numbers

    A. Orally 1. Through the anus

    B. Lingually 2. Into a vein

    C. Rectally 3. Via the mouth

    D. Intravenously 4. Above the root of the tongue

    E. Transdermally

    46. Pair the letters and the numbers

    A. Intragluteally 1. Under the central spinal meninx

    B. Intraarticularly 2. Into a joint

    C. Intrathecally 3. Into a buttock muscle

    D. Sublingually 4. Under the tongue

    5. Under the skin

    47. Pair the pharmacies and their activities

    1. A hospital pharmacy

    2. A community pharmacy

    3. A handling pharmacy4. A sub-pharmacy

    A. There is no community pharmacy but there is a local doctor

    B. This pharmacy is allowed in a settlement where there is no community pharmacy

    C. The basic unit for drug supply

    D. This pharmacy functions during a defined part of the year

    E. This pharmacy manages the hospital drug supply

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    48. Pair the volumes and the contents of Ph. Hg. VII.

    a. Volume I

    b. Volume II

    c. Volume III

    d. Volume IV

    1. It contains tables

    2. It contains common prescriptions, analytical methods, the quality requirements of

    packing materials, the reagents used et c.

    3. It contains chemical drug ingredients

    4. It contains volatile materials, plant materials, drugs, radioactive drugs,

    immunological and blood preparations, and surgical materials

    49. Pair the discoverers and their discoveries

    1. Vesalius A. Pioneer of anatomical research

    2. Sertrner B. Inventor of the microscope

    3. Jenner C. Isolator of morphine

    4. Loevenhoeke D. Developer of variola vaccine

    E. Discoverer of penicillin

    50. Pair the persons and their activities

    1. Elemr Schulek

    2. Sndor Mozsonyi

    3. Lajos Winkler4. Jnos Kabay

    5. Kroly Than

    A. He developed a method for the preparation of morphine

    B. He was the director of EGYO

    C. He organized Hungarian drug control

    D. He had a special interest in water analysis

    51. Pair the laws and the dates of their introduction

    1. 1552 A. Law XXX on pharmacy

    2. 1876 B. Statuta civitatis budensis

    3. 1948 C. Law XIX on organisation of public health

    4. 1244-1421 D. Ordo Politiae

    5. 1972

    52. Pair the laws and the dates of their introduction

    1. 1644 A. Law LIV. on the Hungarian pharmaceutical chamber

    2. 1994 B. Lex Sanitaria Ferdinanda

    3. 1770 C. Law II. relating to public health4. 1972 D. Generale normativum in re sanitatis

    5. 1876

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    53. Pair the following ideas

    1. scat. orig. A. Globule

    2. lag. orig. B. Original box

    3. amp. C. Original bottle

    4. glob. D. AmpouleE. Suppository

    54. Pair the following ideas

    1. f.l.a A. With poison mark

    2. q.s. B. Mix, give, mark

    3. sub. sig. ven. C. As much as is enough

    4. M.D.S. D. According to the regulations

    5. A.U.V.

    55. Pair the following ideas

    1. Drugs marked with one cross A. Narcotics

    2. Drugs marked with two crosses B. Hypnotics, sedatives

    3. Drugs marked with one empty cross C. Strong drugs

    4. Drugs marked with two empty crosses D. Poison

    E. Not strong drugs

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    4. Relat ion analysis

    56. Pharmaceutical history Researches are divided into analysis and synthesis, because

    analysis in association with ancillary sciences can furnish material evidence and data.

    57. The two outstanding pharmaceutical historians in the last century were Jzsef Ernyei

    and dr. Jnos Halmai. From 1947 dr. Halmai attained the inclusion of this science as an

    obligatory subject at university.

    58. Among the ancient Jews, the rules of public health were presented as religious

    commands, because these rules were justified in the hot climate.

    59. The drugs available to the Chinese were always very rich. They used numerous plant

    and animal preparations, and possessed anaesthetics and narcotics. Their Pharmacopoeia

    is 5000 years old.

    60. Hippocrates is called the father of medical science, because he was prepared to dissect

    the human body.

    61. Greek doctors mastered the healing profession in their schools, because they took the

    Hippocratic oath at the end of their education.

    62. Besides his medical practice, Galenus dealt considerably with anatomy and physiology,

    and due to this activity he was the first to distinguish arteries from veins.

    63. Paracelsus was the first to use the mineral materials and metals in curing because

    mercury was efficacious against syphilis.

    64. Paracelsus introduced the idea of an active ingredient because he tried to isolate the

    ingredients from plants by chemical methods (cooking and steaming).

    65. Pharmaceutical education started in Nagyszombat in 1569, because Maria Theresia

    founded the Pharmaceutical Faculty there where training was provided in two subjects.

    66. 1811 was the first year for a doctoral diploma in pharmacy to become available; before

    that pharmacists were awarded other doctoral qualifications.

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    67. Pharmacy is based on natural science, because it makes use of different sciences

    applying special ideas in drug research and drug manufacturing.

    68. Health education activity belongs to the ANTSZ, because the NEVI, as part of the

    ANTSZ, carries out this activity.

    69. Distribution of drug information belongs to the National Pharmaceutical Institute, which

    functions under guidance of the Health Ministry, because the Pharmaceutical Chamber

    leads this activity.

    70. The goal of health education is to provide information for health-political decisions

    because the health education has pharmaceutical aspects as well.

    71. Drugs are materials used for therapeutic, diagnostic and preventive goals, because these

    materials influence the vital processes of the body.

    72. Effective preparation are preparations which contain natural materials with biological

    effects, because these preparations can be used without a medical prescription.

    73. At the present time we no longer use drugs of mineral origin, because they do not have

    therapeutic effects.

    74. The proportion of drugs of animal origin is very low, because they are used only in

    some dosage forms such as ointments.

    75. Drugs of plant origin are used in the case of a decreased gland function, because there is

    no other possibility.

    76. The drugs of plant origin are very important in therapy, because their mechanisms ofaction are known.

    77. The material condition (equipment and instruments) in pharmacies are determined by

    norm because pharmacies have to meet standards of public health.

    78. Pharmacopoeias are not standards because they are collections of prescriptions of

    manufacturing and drug control.

    79. FONO is a collection of standard prescriptions because it is a supplementary volume of

    the pharmacopoeia.

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    80. The prescriptions of the medical FoNo differ from those of the pharmaceutical FoNo,

    because the prescriptions are given in a pharmacological classification.

    81. Drug ordering and distribution are the same activities, because drug distribution is the

    activity in which the pharmacist gives out the drug in response to the doctor's

    prescription or the patient's request.

    82. The Assyrians already used enteral solutions, which they named water of life, because

    they believed that the cold water cure was very effective.

    83. The ancient Jews had an accurate knowledge of anatomy because they often performed

    dissection.

    84. There were health regulations in The Talmud, because the ancient Jewish pharmacists

    prepared decoctions, liniments, ointments.

    85. Galenus acted as a clerical doctor, because he set up the diagnoses after establishing the

    case histories.

    86. Pharmacists take the Hippocratic, oath because the oath does not prohibit the trading in

    narcotics.

    87. Galenus published methods for the recognition of drug imitations, and therefore the

    essence of quality control today is the discovery of drug imitations.

    88. Galenus laboratories prepare individual drug preparations, because Galenus used

    individual drug ordering.

    89. Alchemy is the mother of pharmaceutical technology, because its goal is to prepare theorganic gold preparations used in therapy.

    90. In Hungary Richter Gedeon first started the manufacturing of drugs from animal organs,

    because the pharmaceutical works owned by his father gave him excellent conditions.

    91. The law of Maria Theresia published in 1776 was very important from the aspect of

    health care because it determined the scope of activity of doctors, surgeons and

    gynaecologists.

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    92. Among the primitive Hungarians the shaman was the doctor-pharmacist of the tribe who

    had contacts with the gods, because he used only special preparations.

    93. The only surviving account of Hungarian pharmacy is the Pray-codex, because it was

    probably prepared between 920 and 950.

    94. The name of some drugs featured a connection with Venice, because pharmacies

    obtained drugs from Italy until the 16th century.

    95. The publications of pharmacists started in the first part of 19th Century, because the first

    truly pharmaceutical paper was published only in 1848.

    96. The importance of the activity of Paracelsus was the discovery of metals with

    physiological effects, because he introduced the idea of active ingredients.

    97. The first Hungarian Pharmacopoeia was linked with the name of Richter Gedeon

    foundation, because he isolated morphine from the poppy-stem.

    98. The great discovery of Albert Szent-Gyrgyi was vitamin C, because he isolated it first

    in the world from adrenal gland and paprika.

    99. Law XIV. in 1876 first determined the idea and the place of pharmacy, because it

    declared that a pharmacy was a public health institute and differed from other shops.

    100. A small therapeutic index means a wide effect, because the therapeutic index is the

    quotient of the curative dose and the tolerate dose.

    101. Two empty crosses denote poisons, because higher doses of poisons cause serious and

    possibly permanent harm.

    102. Community pharmacy is the basic institute of drug supply, because its activity is to

    fulfil the drug demands of the population.

    103. The supply of drug information is activity to inform doctors about the optimum drug

    treatment, because the promotion of drugs is prohibited.

    104. Ready-made drugs are prepared from raw materials for prescription, because these

    preparations are suitable for personal therapy.

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    105. Pharmacists vow discretion in their pharmaceutical oath, because the composition of

    preparations should not be told to patients.

    106. A pharmaceutical assistant is a direct co-worker of a pharmacist who knows the

    connection of the pharmaceutical activity during the work.

    107. Preparations with a curative effect can be used without medical prescriptions, because

    they contain materials of natural origin.

    108. Only a doctor can prescribe a drug, because a drug is a material used for the treatment,

    observation and prevention of human and animal pathological conditions.

    109. Registered drugs are called special drugs, because treatment was previously defined by

    ready made preparations.

    110. The first volume of Ph. Hg. VII contains tables, because the task of the Pharmacopoeia

    is to ensure the expert preparation and reliable quality of drugs.

    111. The marketing of drugs is the responsibility only of the pharmacies (except for the sub-

    pharmacies), because only qualified workers can safety handle drugs.

    112. The task of drug information is to inform doctors about new drugs and new indications

    of old drugs, because the pharmacist is the person who not only gives out drugs, but also

    knows all their aspects.

    113. 113. Pharmacists can not recommend drugs, because quackery can cause serious harm.

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    5. Answer key

    Simple choice

    1 C2 A3 B4 C

    5 B6 A7 E8 C

    9 E10 C11 B12 E

    13 D14 D15 B16 C

    Multiple choice

    17 E

    18 E

    19 C20 E21 C

    22 A

    23 C

    24 A

    25 E

    26 A27 D28 E

    29 C

    30 D

    31 C

    32 E

    33 D34 B35 D

    36 E

    37 C

    38 E

    39 A

    40 C41 E42 A

    43 D

    Pairing

    44. 1-A

    44. 2-A44. 3-B

    44. 4-A

    44. 5-B

    44. 6-A

    44. 7-B

    45. 1-C45. 2-D

    45. 3-A

    45. 4-B

    46. 1-C

    46. 2-B

    46. 3-A

    46. 4-D47. 1-E

    47. 2-C

    47. 3-A

    47. 4-B

    48. A-2

    48. B-348. C-4

    48. D-1

    49. 1-A

    49. 2-C

    49. 3-D

    49. 4-B

    50. 1-C50. 2-B

    50. 3-D

    50. 4-A

    51. 1-D

    51. 2-C

    51. 3-A51. 4-B

    52. 1-B

    52. 2-A

    52. 3-D

    52. 4-C

    53. 1-B

    53. 2-C53. 3-D

    53. 4-A

    54. 1-D

    54. 2-C

    54. 3-A

    54. 4-B55. 1-C

    55. 2-D

    55. 3-B

    55. 4-A

    Relation analysis

    56. B

    57. B58. B

    59. B

    60. B

    61. B

    62. A

    63. B

    64. B

    65. D

    66. B

    67. A

    68. C

    69. C

    70. E

    71. C

    72. B73. E

    74. A

    75. E

    76. C

    77. A

    78. D

    79. C

    80. D

    81. D

    82. D

    83. E

    84. B

    85. D

    86. E

    87. C88. D89. E90. C91. E92. B93. E94. A95. A96. B97. C98. A99. A

    100. A

    101. D

    102. A103. C104. C105. C106. B107. B108. D109. A110. D111. A112. B113. D