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Plasma fluid part 55% of blood volume Contains/transports the proteins, red
blood cells, white blood cells, platelets, essential nutrients, enzymes, hormones, gases, & organic slats
Red blood cells, white blood cells, platelets 45% of blood volume
Produced in bone marrowHave nucleus in bone marrow
Loses nucleus once in circulationUsed RBC are destroyed by the liver
and spleen Life span 120 days (no nuclei)
Protein – consists of a red pigment containing iron
Transports oxygen & a little carbon dioxide
The heme consists of 4 molecules of iron attached to the proteins
1 L of blood can carry 3ml of O2 without hemoglobin
1L of blood can carry 200ml of O2 with hemoglobin
O2 attached to hemoglobin appears red
O2 freed & it reflects blue light Shape of hemoglobin molecule changes
shapeOne red blood cell can have 280
million hemoglobin
Body contains 5 L of blood5.5 million per ml of blood in males4.5 million per ml of blood in femalesQuanity is influenced by:
Sex Health Age Altitude ( up to 8 million cells/ml)
Lack of rbc or hemoglobin that decreases the quantity of O2 delivered to the body
Reason are numerous Loss of blood (hemorrhages, ulcers) Lack of dietary iron
Essential part of the immune systemMany different leukocytes
Monocytes Lymphocyte Eosinophil Basophil Neutrophil
700 red blood cells for every white globule
Fragments of cells necessary for coagulation (clotting)
Circulate in blood (7 days)Trillions in circulation
Broken blood vessel Plateles release thromboplastine Triggers a set of reactions leading to
formation of clot Sticky network of protein fibers (fibrin)
forms over the injury and stops the blood cells
Dry & thick crust forms
Hereditary bleeding disorder (males)Prolonged bleedingDifficulty clotting – may bleed longerAffects 1:10,000 male birthsFemale carriers occasionally have
bleeding symptomsFactor VIII or IX