“I’m working closely with people from different teams across the

world to improve understanding so we can work together even better.”

Roche, UK

Roche Product DevelopmentWelwyn Garden City, Hertfordshire

Senior Technical Programmer

We wish to appoint experienced programmers in the UK to support our growing global drug development portfolio. The ability to carry out and supervise statistical programming components of a clinical trial is a must. This individual will ensure study processes are consistent with company standards. Working in a matrix team, you will plan, manage and analyse clinical trials. You will also contribute to global initiatives. The successful candidate will assist in the development of several trial analyses and data presentations relating to efficacy and safety data under the direction of a Project Programmer (or designee).

Senior Programmer

We wish to appoint experienced programmers in the UK to support our growing global drug development portfolio. The ability to carry out statistical programming components of a clinical trial is a must. This individual will program to study processes and company standards. Working in a matrix team, you will plan, manage and analyse clinical trial data. You will also contribute to non project initiatives. The successful candidate will assist in the development of a study trial analyses and data presentations relating to efficacy and safety data under the direction of a Project Programmer (or designee).

To be successful within these roles you will have:

• Educated to degree level preferable in IT, Life Sciences, Statistics, Computer Science, Mathematics

• A very good knowledge/experience of international clinical research and drug development

• Ability to process information, analyse data, and reach conclusions based on sound reasoning

• Ability to work in a global team

• Experience in using SAS

Positions are available immediately.

We offer a competitive salary plus the excellent benefits you would expect from a blue-chip organisation, including a genuine interest in your development and progression.

Are you looking for a challenge?Opportunities for Senior Technical Programmers and Senior Programmers at Roche Products, Welwyn Garden City, Hertfordshire.

Pioneering healthcare

If you join Roche, you’ll be part of a company that has played a pioneering role in UK healthcare for more than a hundred years. Innovation has always driven us. We’ve made our mark through early engagement in market trends and sometimes created entirely new markets. We’ve developed state-of-the-art technology with unconventional methods and ideas. By preventing, diagnosing and treating a wide range of diseases, our products and services have enhanced the health and quality of life of people around the UK.

Today, we’re one of the world’s leading research-focused healthcare groups. From offices and labs across 150 countries, including the UK, we remain committed to improving patients’ lives.

Our heritage

In 1908, 12 years after the company was founded by Fritz Hoffmann-La Roche, our first UK office opened for business in London to market products that included a heart treatment and a cough medicine. By the 1920s we had started first packaging and later manufacturing medicines from a site in north London.

In 1937, Roche moved out to Welwyn Garden City in Hertfordshire. Everything was brand new – the town, the offices, the factory, the laboratories and even a new UK research team.

Throughout the rest of the 20th century, our UK presence expanded across the UK as the Roche Group and its products continued to grow and diversify. By the 1990s, our businesses in pharmaceuticals, diagnostics, over-the-counter medicines and vitamins and bulk vitamins and fine chemicals were spread from Ayrshire to Hampshire.

This century, Roche has focused on two core businesses – pharmaceuticals and diagnostics. In pharmaceuticals, our UK development and sales and marketing teams have gone from strength to strength and moved into a brand new headquarters building in Welwyn Garden City in 2005.

By 2008, we were celebrating our centenary in the UK – a remarkable achievement in an ever-changing industry.

Our company today

Today, Roche is one of the leading research-driven healthcare companies in the world with a headquarters in Basel, Switzerland, and operations in more than 150 countries. As part of our 800-strong pharmaceutical development team based in the UK, you’ll be helping to drive forward the next generation of treatments by designing and leading clinical trials into potential new medicines.

Our sales and marketing colleagues support healthcare professionals with a portfolio of innovative treatments. We’re the leading provider of cancer treatments in the UK and are strong in several other important therapy areas, including viral diseases and transplantation. In fact, we estimate that more than three million patients in the UK are treated with a Roche medicine every year.

Our responsibility

As a leading healthcare company dedicated to tackling some of the world’s most aggressive diseases, Roche inherently believes in improving the quality of people’s lives.

We’re committed to being a good corporate citizen in the UK. We take very seriously our responsibilities to our employees, to the communities in which we operate and to the environment around us. We’re also committed to maintaining the highest standards in science and business.

Every year, our pharmaceutical teams raise money for their charity of the year. Individuals also raise money themselves for causes close to their hearts and they volunteer their time to support local organisations.

Our employees also join their colleagues from more than 100 Roche sites to take part in the Roche Children’s Walk.

Our Company

Top class facilities Modern, dynamic and innovative – our UK headquarters building is a fantastic place to work. Purpose built for Roche, Hexagon Place was designed to encourage interaction. At its heart is a central “street” with a coffee shop and plentiful seating where people gather for informal meetings, to chat to friends or to take a break.

Large open plan work areas provide space and quiet for concentrated working, supported by a network of small meeting rooms and areas where you can print, fax or copy or make a free hot drink. A popular restaurant serves breakfast and lunch and the main conference and meeting suite is equipped with the latest audio-visual facilities. Our on-site library provides a wealth of research and learning resources and our wellness centre provides occupational health advice, a well-equipped gym and exercise classes.

Our footprintDesigned to minimize its environmental impact, including cutting C02 emissions to around 20% below building regulation limits, Hexagon Place won a clutch of awards when it was completed and opened in 2005.

It received an ‘excellent’ rating under the Building Research Establishment’s Environmental Assessment Method (BREEAM), with a score of 10 out of 10 in recognition of its sustainable design and environmental performance. In the British Council for Offices 2006 awards, it achieved the highest accolade of the ‘Best of the Best’ in the corporate workplace category.

Today, our recycling service aims to minimize the impact that our office has on the environment on a day-to-day basis. Most areas have central waste disposal areas to increase and encourage recycling. We recycle metal, plastics, glass and electrical appliances as well as paper and cardboard. None of our waste goes to landfill and we generate electricity from incinerated general waste. We also actively encourage employees to use alternatives to travelling alone by car to get to work. We support those who car share, use public transport, cycle or walk to work and provide a shuttle bus between our site and the town centre for those who travel by train or bus.

Our flexible approachOur pharmaceutical development teams in the UK were the first to adopt a flexible working scheme that we call “phlexible office”. The new approach was introduced in response to the continued success and growth of development teams in the UK.

Phlexible Office allows individuals to apply for one of four different working styles, one of which includes working from home for up to 60 per cent of their time. If a role is suitable, we provide all the furniture, equipment and technology, including meetings software which enables teams to share and work on live documents.

Almost half of our development teams now regularly work from home. This has allowed us to spend money on science, rather than offices, and to attract and retain more talented people. It has also helped individuals reduce their commuting time and emissions, be more productive and juggle other commitments.

Our locationHertfordshire is a county of contrasts. Home to around a million people, its thriving modern towns are connected to London by fast transport links. Between them is a network of sleepy villages and farms amid picturesque countryside – two thirds of which is designated as Green Belt.

It’s this combination of old and new, urban and rural, that gives Hertfordshire such an enviable quality of life and makes the county such a popular place to live and work. Superbly well connected, the county has four motorways, is within easy reach of Luton, Stanstead and Heathrow airports and has five main train lines running into London and out into East Anglia, the Midlands, Wales and the north.

Financial services, the computer industry, pharmaceuticals and the film and media sectors are major employers of a highly skilled workforce. Economic success is supported by some of the best facilities for education in the country. Out of work, there’s plenty to see and do from visiting historic houses to shopping to sport. London, of course, is just on our doorstep.

At Roche, we know that relocating is never easy so if you’re thinking of joining us and moving to the area, we’ll work with you to help you move and settle in as quickly as possible.

Our Site

Join the best

Roche excels in science, innovation and business by consistently employing the best people. Our people are passionate about making a difference to patients’ lives. They lead and drive change and they live our corporate values of integrity, courage and passion.

These ambitious and forward-looking employees are self-starters who continually strive to develop innovative, high-quality solutions for unmet medical needs. They’re people who will inspire you every day.

Roche has so much to offer, whether you have a background in medicine, biology, biochemistry, biotechnology, pharmacy, statistics, programming or another specialism.

So come and join us. There’s no better place to make your mark.

The following is what people have said that work for Roche:

“A lot of people have been here a long time which I think is a good sign in an industry where people tend to move around. I’ve been able to move into different roles that have given me the challenge I need and the opportunity to carry on learning and growing. That has certainly kept me motivated and that’s why I’ve been here for so long. I have a lot of loyalty for Roche – Roche has been good for me and I hope that I’ve been good for them.”

“I could have gone into a number of fields but I wanted to do something where I could feel I was making a difference to people’s lives. That’s why I love what I do now. I want to see the company continue to grow so that we can continue to improve people’s lives and make a difference.”

“Joining Roche was like coming home. I love my job and work with such a great bunch of people who are passionate about patient safety.”

“I’m lucky - I enjoy my job and work with some brilliant, experienced people. If you look at all the products that Roche has brought out and the difference they have made to people’s lives, it’s pretty cool to be working for such a company. With the focus on personalised healthcare, I can’t see us being anything other than successful in the future.”

Our People

Join the innovators For over a century, Roche has stood for innovation and entrepreneurship. We focus on developing medicines and diagnostics that will help patients live longer, better lives. We strive to address unmet medical needs through excellence in science.

Unrivalled expertiseRoche has an unparalleled expertise in molecular biology within both its pharmaceuticals and diagnostics divisions.

Over recent decades, we’ve brought numerous innovative and ground-breaking new products to market. Now our research and development teams are now working on a new generation of medicines for patients suffering from cancer, metabolic and autoimmune diseases, viral infections and disorders of the central nervous system (CNS).

We aim to be different. We’re focusing our sights and our resources on a highly differentiated development portfolio of first-in-class or best-in-class medicines.

An innovative approach Understanding the complex biology of disease is the biggest challenge we face in developing new and better medicines and diagnostics.

We believe that scientific breakthroughs are most likely to occur when scientists are free to tackle problems from different angles and in different ways. Our scientists have this freedom. Our structures in research and early development are designed to promote a diversity of views, cultures and approaches. The result is a natural environment for creativity and innovation.

Genentech Research and Early Development (gRED), Pharma Research and Early Development (pRED), Roche Diagnostics and Chugai all operate independently within the Roche Group. Individually, they focus on new drug targets and new molecular entities. Together, they form the hubs of an innovation network that includes alliances with over 150 outside companies.

Excellence in development A fascinating and enviably strong pipeline is being driven forward to market by our clinical development teams who are based in Switzerland, the UK, the United States, Germany, Austria and Australia.

Welwyn Garden City in the UK is the base for around 800 development professionals. From here, we lead international trials,

design clinical development programmes, undertake medical evaluation of patient safety issues, lead the way in translational and biomarker development, manage UK clinical trial centres and drive regulatory submissions for new products.

Our UK teams, who work in close collaboration, include:

• Medical Science – providing high-quality scientific and medical expertise to the development effort

• Operations – the home of clinical study management, clinical study monitoring. They take responsibility for the planning and implementation of high quality clinical programmes and provide input on specific scientific, medical, legal and commercial requirements

• Regulatory Affairs – developing and implementing regulatory strategies for the global registration and ongoing maintenance of our products

• Quality Assurance – helping to achieve and maintain high quality standards in clinical development, trial systems and processes

The future is personal For Roche, the future is personal. Our expertise in molecular biology, and our strength in both diagnostics and pharmaceuticals, enables us to play a pioneering role in advancing the move towards “personalised healthcare”.

From discovery to commercialisation, our world-class pharmaceuticals and diagnostics research organisations are working together to create better, more cost effective treatment options tailored to patients’ needs.

Our aim is to use insights at a molecular level into how people develop diseases and how they respond to treatment to develop solutions tailored to the needs of different sub-populations of patients.

Truly personalised healthcare is an ambitious goal, but Roche already has several products on the market in the UK. We’ll continue to lead the way.

Our long term viewRoche takes a long-term perspective. Backed by a stable majority ownership dating back over 100 years, we keep our sights on sustainable long-term growth rather than short-term gains. This is reflected in the company’s incentive system and approach to succession management, and in far-sighted business moves such as our early investments in biotechnology.

The Science

In joining Roche you not only contribute to a leading independent healthcare company but you get to enjoy an excellent range of benefits. Your total remuneration is reflected in your salary and through schemes that reward individual and team performance. On top of this, there are core benefits that Roche provides to all employees and benefits that you can choose.

My Total RocheFlexible BenefitsMy Total Roche allows you to select which benefits best fit your lifestyle. Many of the benefits save you tax and/or National Insurance as they are provided through a salary sacrifice arrangement.

Holiday Buy: allows you to purchase up to an additional 5 days of annual leave.

Childcare Vouchers: gives you the opportunity to pay for a portion of your childcare expenses free of tax and National Insurance.

Charity Giving: an easy way to donate to the charities you support.

Private Medical Insurance: covers the costs of a range of medical treatments, up to limits for certain acute conditions.

Health screen: is a review of all aspects of your health, fitness and lifestyle to help detect some diseases before they become more serious. An assessment can also be selected for your partner.

Health cash: provides cash benefits to cover a wide range of everyday healthcare expenses for you and your family.

Dental Insurance: reimburses you for dental expenses for you and/or your family.

Pension: Roche offers permanent employees a Defined Contribution (money purchase) scheme. You sacrifice 4% of your pensionable salary while the company contributes a further 8%. You are also able to invest additional contributions into your own personal pot.

Critical Illness Insurance: provides you with a tax-free lump sum following the diagnosis of an eligible condition for you and/or your partner.

Additional Life Assurance: is an opportunity to purchase Life Assurance for your partner or to increase the level of cover which Roche already provides you.

Travel Insurance: very competitive travel cover for you and your family.

Life AssuranceThe Roche Pension Fund provides life assurance cover to all employees at no additional cost to you. If you join the pension fund the cover is 4 times your pensionable salary or 2 times if you are not a member of the pension scheme.

Fixed-term Employee PensionRoche offers a stakeholder pension to enable fixed-term employees to build up an individual pension fund in their

own name.

Roche Connect You can invest for the future and share financially in the success of Roche by purchasing Roche Genussscheine

(non-voting equity securities) and receive any associated dividends. Roche pays a discount of 20% on the Roche Genussscheine you purchase through the Plan.

Work Life BalanceHolidays: you are entitled to 25 days paid annual leave each year, plus 8 paid public holidays. If you join during the holiday year (January to December) your entitlement will be prorated.

Family Support: we recognise that people have a variety of different commitments outside of work, from children to elderly relatives. That is why Roche wishes to support maternity, adoption, paternity and parental leave and flexible working. Roche supports employees by providing a number of payments in addition to the statutory minimum.

Employee Assistance Programme: is a confidential service offering prompt support on domestic, work or personal issues provided by an entirely independent external company.

Sports and Social Club: is managed by an enthusiastic committee of volunteers who run events for the benefit of Roche employees and helps fund clubs within the company.

Benefits at Roche

Occupational Health, Safety and the Environment: Roche is committed to being a good corporate citizen, taking our responsibilities to our employees, to the third parties who work with us, to the communities in which we operate, and to the environment around us very seriously. The on-site Occupational Health, Safety and Environment Department provides specialist advice and expertise to enable employees at all levels to fulfil their health, safety and environmental responsibilities, as well as offering trained support from Occupational Health professionals.

The on-site Occupational Health Centre provides a great range of free services, including:

• Health Checks (including cholesterol and blood pressure)

• Well Woman (cervical cytology and mammography)

• Well Man (prostate screening)

• Support to Stop Smoking

• Weight Matters and Dietary Advice

• Stress Counselling

• General Health Advice and Support

The Centre has a range of Therapists, such as, Physiotherapy, Chiropody, Reflexology, Massage, Nutritional Analysis, Life Coaching and Clinical Hypnotherapy.

Hexagon Place Terrace Restaurant: our subsidised restaurant serves a great selection of breakfasts in the morning, while for lunch there are hot dishes, a deli sandwich section and a self service salad bar.

The Street Café: is an ideal place for a break or an informal meeting where you can enjoy the finest coffee, teas, hot chocolates, cold drinks and food to go. Roche Lifestyle Centre: is located on the ground floor of Hexagon Place and includes a purpose built gym and studio. The gym has a range of cardio-vascular and resistance equipment, which is complimented with a busy studio programme.

Travel to WorkLoans: most people want to perfect combination of green and convenient travel. With this in mind we offer interest free loans for annual season tickets on public transport or a loan to buy a bicycle.

Green Travel Plan: there is a free shuttle bus service linking Roche with the Welwyn Garden City bus/train station, plus dedicated secure storage areas for motorcycles and bicycles.

This information is subject to change at the discretion of Roche

• Creating an efficient global organization with common processes and tools allowing for fluid resourcing across Programming function functions and sites

• Being recognized as effective and active contributors across Late Phase, Early development and other functions and partners

• Successfully recruiting and retaining highly motivated professionals with an ongoing emphasis on the “analyst” mindset

• Continually assessing our deliverables and increasing efficiency by identifying and implementing improved technologies and processes

Key Deliverables and Skills Used Roles Within SPA - Career Development

Statistical Programming and Analysis (SPA) Biometrics

Clinical Study Protocol

Data and Reporting Standards

Clinical DataOther Data

SourcesStatistical

Analysis Plan

Customer Focus

Project Management

Process Improvement and

Efficiencies

Analyst Mindset

Statistical Programming

Technical Skills

Data to Support Decision Making

CSR Outputs E-Submissions Publications

Programmer

Senior Programmer

Senior Technical Programmer

Project Programmer

SPA ManagerBusiness Technical Specialist

Team Leader

Head of SPA

Mission: We prepare data for interpretation to enable decision making the global Statistical Programming and Analysis department provides timely and accurate analysis and reporting for drug development projects by:

Develop the analytical strategy, stochastic methodologies, and quantitaive evidence needed to inform decisions and answer critical questions about the therapeutic benefit and risk of our molecules to patients.Roche SPA sites working together globally: Welwyn, Basel, Nutley, South San Francisco, Shanghai. Business Process Outsourcing partnership in India.

Working Globally

South SanFranciscoUSA

NutleyUSA

WelwynUK Basel

Switzerland

MumbaiIndia

ShanghaiChina

Job description

Are you looking to make a difference to clinical trial projects? Within the Statistical Programming Analyst (SPA) Group at Roche you be asked to contribute and lead in the whole lifecycle of a clinical trial, across project and therapeutic area. Our programmers are expected to be experts in SAS programming, analysing data, problem solving, decision making and communication so that they can work in a global environment. He/She ensures that the objectives, standards, deadlines and other requirements set by SPA management with respect to statistical programming processes and software documentation are attained. You deputize upon request for the Project Programmer.

We are recruiting for experienced programmers to work within our team in Welwyn as part of the role you are expected to perform a number of duties within the project such as:

• Develop and document statistical programming standards in accordance with current statistical programming practices and regulatory authority requirements.

• Provide technical advice and support to members of biometrics and other stakeholders.

• Takes responsibility for planning, development, validation, documentation and maintenance of project generic tools.

• Informs and makes recommendations to the Project Programmer on critical issues within a SPA tool development project.

• Prioritizes and delegates tasks based on the importance of the deliverable and awareness of overall timelines in order to efficiently produce high quality deliverables.

• Program, validate and document software in SAS following statistical programming standards and ensures its availability to stakeholders.

• Assists in the development of several trial protocols, trial analyses, editing procedures and data presentations relating to efficacy and safety data.

• Activities performed within the project are executed in a timely manner and to the required high standards

Non drug development work can include

• Keep abreast of statistical SAS programming methodology, applications and software developments through literature and attendance at meetings.

• Maintain familiarity with regulatory authority guidelines relating to biometrics, data reporting and medical issues in project areas.

• Participate in and contributes to internal training programs.

• Make presentations at professional forums.

• Assess, recommends and develops new standards, policies and procedures.

You will have the opportunity to lead and contribute to function process, polices and initiatives working in teams across the various sites globally.

Who you are

You should be educated to degree level preferable in IT, Life Sciences, Statistics, Computer Science, Mathematics or other analytical field while possessing a very good knowledge/experience of international clinical research and drug development.

You will be confident in the use of computers with a very good knowledge of SAS.

The right candidate will also be able to communicate clearly and effectively in written reports, data presentations and meetings as required. (Fluency in English is a prerequisite) You should also be able to easily establish and maintain good working relationships and takes cultural and value differences into account in dealings with others.

Senior Technical Programmers

Job description

Are you looking to make a difference to clinical trial projects? Within the Statistical Programming Analyst (SPA) Group at Roche our programmers you will be asked to contribute in the whole lifecycle of a clinical trial. Our programmers are expected to be experts in SAS programming, analysing data, problem solving, decision making and communication so that they can work in a global environment. He/She ensures that the objectives, standards, deadlines and other requirements set by the project with respect to statistical programming processes and software documentation are attained.

We are recruiting for experienced programmers to work within our team in Welwyn as part of the role you are expected to perform a number of duties within the project such as:

• Develop and document statistical programming standards in accordance with department and project requirements.

• Provide technical advice and support to junior members of the department.

• Takes responsibility for planning, development, validation, documentation and maintenance of your programming task.

• Informs and makes recommendations to the study and/or project lead on critical issues within clinical trial reporting.

• Program, validate and document software in SAS following statistical programming standards and ensures its availability to stakeholders.

• Assists in the development of trial protocols, trial analyses, editing procedures and data presentations relating to efficacy and safety data.

• Activities performed within the project are executed in a timely manner and to the required high standards

Non drug development work can include

• Keep abreast of statistical SAS programming methodology, applications and software developments through literature and attendance at meetings.

• Contributing to how standards, policies and procedures can be improved.

You will have the opportunity to contribute to function process, polices and initiatives working in teams across the various sites globally.

Who you are

You should be educated to degree level preferable in IT, Life Sciences, Statistics, Computer Science, Mathematics or other analytical field while possessing a very good knowledge/experience of international clinical research and drug development.

You will be confident in the use of computers with a very good knowledge of SAS.

The right candidate will also be able to communicate clearly and effectively in written reports, data presentations and meetings as required. (Fluency in English is a prerequisite) You should also be able to easily establish and maintain good working relationships and takes cultural and value differences into account in dealings with others.

Senior Programmers