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Proprietary and Confidential. ©2013 Syapse Enabling Clinical Omics

Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

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Page 1: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Enabling Clinical Omics

Page 2: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

About Me

Stanford Phd Dropout (Neuro)

Alzheimer’s ResearchBiopharma Clinical & Biz Dev

Founder, Syapse (at Stanford)Board, SXSW Accelerator

@[email protected]

Page 3: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Problem

38%

40%

43%

50%

70%

75%

Asthma Drugs Arthritis Drugs Cancer Drugs

Antidepressants Diabetes Drugs Alzheimer’s Drugs

Page 4: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Personalized Therapies

Page 5: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

LS Crohn’s UlcerativeColitis

HealthySmarr, Calit2

Omics: More Than Just Genomics

Page 6: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Microbiome in Clinical Care

Page 7: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Single Patient Multi-Omics Profile

Genome Proteome

Transcriptome

Microbiome

Epigenome

Immunome

Metabalome

Page 8: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Rapidly Falling Costs

Page 9: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Problem

API for healthcare

Page 10: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Problem

No or Bad Software

Page 11: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Enabling Clinical Omics

“A startup called Syapse is trying to bring the world of “omics” under control with a new data management platform based on some of the same general techniques that also power Facebook’s Graph Search.”

- GigaOM

Syapse software enables the generation and use of omics profiles at laboratories and healthcare

providers to diagnose and treat patients.

Page 12: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Syapse Product Suite

Syapse forHospitals

Syapse forLabs

Syapse Platform

Page 13: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Syapse Platform

Syapse Platform(semantic computing)

Omics Profiles

Phenotype& EMR Drugs

& Trials

Outcomes

Knowledge & Rules

Page 14: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Clinical diagnostics workflow

Curation

Sample Accession& Processing

Results Storage

AnalyticalPipeline

ReportDelivery

OutcomeTracking

Syapse for Labs

Report Generation

Syapse for Labs

OMEResults Portal

Interfaces to 3rd-party tools

Page 15: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Initiatives

Free the Data

www.free-the-data.org

Page 16: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

About Syapse

Team of 15, based in Palo Alto

We’re hiring!

Page 17: Syapse Presentation at Health2.0 Silicon Valley meetup 7-16-13

Proprietary and Confidential. ©2013 Syapse

Enabling Clinical Omics