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Big (Biomedical) DataPanel discussion
• (Chair) Fiona Nielsen, CEO, DNAdigest and Repositive• Adam Auton, Senior Statistical Geneticist, 23andMe• Mathew Woodwark, Director of Research Bioinformatics,
MedImmune• Eric Little, VP Data Science, Osthus
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21 May 2023
Big Biomedical Data – chair introduction
Pistoia Alliance European Conference 2016
• Fiona Nielsen, CEO of DNAdigest and Repositive
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31 May 2023
Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• High throughput technologies – biology is moving from the lab to the computer
2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Genomes Sequenced
80+ PB
Sequenced every year
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• Growing interest and growing databanks
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• Genomics, Proteomics, metabolomics, all the omics!
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• Challenges in all dimensions of big data: Volume, Velocity, Variety, Veracity
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
Assay Types
Dedicated to…
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
0.2
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200
2000
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Chart Title
Sam
ple
# (L
og10
)
Top 5:GEO (1.8M)PMI Cohort Program (1M)Auria Biopankki (1M)EGA (~0.6M)SRA (~0.5M)
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
Aboriginals
African Americans
Africans
Australians
Chinese
MalaysIndians
DanishDutch Estonian
Russian
European Ancestry
FinnishIcelandic
JapaneseKorean
Latin Americans
Saudi
Swedish
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
9475600
88
660
26
68
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0
23
International
Interesting site to look at: http://omicsmaps.com/stats
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• Challenges in all dimensions of big data: How to collect? How to store? How to analyse?
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• Challenges for international research community: How to work across borders and silos?
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• Additional challenges for biomedical: Data privacy, data governance, patient consent, medical legislation
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• How will the landscape change when genomics moves to the clinic?
?
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151 May 2023
Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• Is Big Data a promise of Big Findings?
?
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• Community-led databanks: patient groups, academia, the general public
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Big Biomedical Data – intro
Pistoia Alliance European Conference 2016
• For our panel discussion: • How can Pistoia Alliance members uncover
value from Big Biomedical Data?
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Big (Biomedical) Data panel speakers:
Pistoia Alliance European Conference 2016
Adam AutonSenior Statistical Geneticist, 23andMe
Mathew WoodwarkDirector of Research Bioinformatics, MedImmune
Eric LittleVP Data Science, Osthus
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191 May 2023
Thanks to our panel speakers:
Pistoia Alliance European Conference 2016
Adam AutonSenior Statistical Geneticist, 23andMe
Mathew WoodwarkDirector of Research Bioinformatics, MedImmune
Eric LittleVP Data Science, Osthus
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