New tools for protein structures and phosphorylation pathways - Sean O'Donoghue

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Round out this year's FOAM with VizBi founder and CSIRO Science Leader Sean O'Donoghue as he takes us through his team's latest work, including an animation about pancreatic cancer.

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New tools for protein structures

http://odonoghuelab.org

Seán O’DonoghueB. Sc. (Hons), Ph. D., FRSC

and phosphorylation pathways

- plus another animation

Monday, 31 March 14

New tools for protein structures

http://odonoghuelab.org

Seán O’DonoghueB. Sc. (Hons), Ph. D., FRSC

Monday, 31 March 14

Monday, 31 March 14

New tools for protein structures

http://odonoghuelab.org

Seán O’Donoghue Julian Heinrich

Monday, 31 March 14

Monday, 31 March 14

Monday, 31 March 14

Visualising Protein Ensembleswith Parallel Coordinates

Monday, 31 March 14

Visualising Protein Ensembleswith Parallel Coordinates

Monday, 31 March 14

Observed Disorder vs. Predicted Disorder

retinoic acid receptorobserved predicted

Monday, 31 March 14

Visually Query and Filter by Principal Components

retinoic acid receptor

Monday, 31 March 14

Visually Query and Filter by Principal Components

retinoic acid receptorJ. Heinrich, M. Krone, S. O’Donoghue, and D. Weiskopf, “Visualising Intrinsic Disorder and Conformational Variation in Protein Ensembles,” Faraday Discuss., 2014.Monday, 31 March 14

New tools for phosphorylation pathways

http://odonoghuelab.org

Seán O’DonoghueB. Sc. (Hons), Ph. D., FRSC

Monday, 31 March 14

Humphrey et al., Cell Metabolism 2013

Monday, 31 March 14

Minard, 1863

Monday, 31 March 14

0 sec 15 sec 30 sec 60 sec 2 min

20 min60 min 10 min 5 min

N U C L E U S

T I M E

M E M B R A N E

M E M B R A N E

Monday, 31 March 14

Monday, 31 March 14

http://odonoghuelab.org

Seán O’DonoghueB. Sc. (Hons), Ph. D., FRSC

Finally: one more animation

Monday, 31 March 14

Sandeep  Kaur

Coming  April  10  -­‐  h6p://vizbi.org/plus

The  Hungry  Microbiome Cancer  is  not  one  disease Type  2  diabetes

Monday, 31 March 14

19

Maja  DivjakWalter  and  Eliza  Hall  Ins0tute,  Melbourne

Type  2  diabetes

Monday, 31 March 14

20

Monday, 31 March 14