Future of Health Care, Medical Tech, Biotech, Pharma, Diagnostics, Wearable health devices - keynote...
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- 1. Dr Patrick Dixon Chairman Global Change LtdFuture of Global
Health and Medical Technology 2020-2030
- 2. Everyhealth trendwill impactallother healthtrends
- 3. Cloud Nanotech Mobile Biotech Genes + Cells Digital Connect
Atoms Converging - Combinations
- 4. Expectconvergence andcompe66on betweenpharma,
biotechandmedtech inndinganswersto majorcondi6ons
- 5. ONEWORD willdrivethe futureofhealth
- 6. The future is about EMOTION
- 7. Demographics willbegreatest predictorof futuredemand
- 8. 1 billion children alive today
- 9. Growthinglobal healthspendwillbe drivenbygrowthof
middleclassin emergingna6ons
- 10. IMF - adjusted for Purchasing Power Parity >40% WDP by
2015
- 11. 300 million move to cities in China and 475 million to
cities in Africa by 2030 ! ! ! ! ! ! ! ! ! !
- 12. Megacities mean greater risks of viral epidemics like Ebola
with global impact
- 13. ! 1 billion over 60 year olds in 10 years
- 14. Europe Dying ! 4 couples to produce single great-grand
child ! S Korea children per couple fell from 6 to 1.2 -
1950-2000
- 15. Title Text Body Level One Body Level Two Body Level Three
Body Level Four Body Level Five
- 16. >65%ofhealth spendwillbe onpeople >65yearsold
- 17. Chronic Conditions Multiple Needs 100 million Americans
have chronic conditions 80% of health spending 88% of all
prescriptions 70% of physician visits 66% Medicare cost = people
with 5+ conditions Almost all caused by people getting older
- 18. Expectmajorglobal demandforpreven6onand
treatmentforcancer,heart, brain,chronicwounds,
infec6ons,infer6lity, arthri6sanddiabetes
- 19. Pharma Companies WILLndnew blockbusterse.g.
Alzheimers/Obesity
- 20. AlzheimerscommonestcauseofdeathinUKwomen
2010-2050demen6a
- 21. 1in3babiesinNewYorkwilldevelop
adult-typediabetes-cost$100bnayear
- 22. Imagingand Diagnos6cswill bedominated by3DandHD
- 23. 27
- 24. Cloud Processing
- 25. Positron emission tomography Magnetic nuclear
resonance
- 26. Imaging and Robotics
- 27. Food moth larva silk gland ! ! Fat cells Cuticular
- 28. Mouse Retina
- 29. Micro-surgery willtransform hospitalcare
- 30. $75bn endoscopy market by 2022 ($23bn 2010)
- 31. 125,000 stents or carotid surgery a year in US
- 32. Lengthof hospitalstay willfallrapidly
- 33. Virtual Medicine
- 34. Wearable HealthDevices willbealmost universal
- 35. Home Tele-Monitoring
- 36. Mostpa6ents willknowmore thantheir physiciansabout
theircondi6on
- 37. Search: know more than your doctor !
- 38. HomeCarewill growveryfast especiallyfor oldpeople
- 39. ! ! Diabetes, congestive heart failure, obstructive
pulmonary 2.2 million at home> $22bn by 2015Mobile
telephony
- 40. Biotechwill drivemost pharma innova6on
- 41. coatings and robots
- 42. Build Nanotech Robots as Biotech Therapies
- 43. Adenovirus contains Math1 gene Turns young ear cells into
hair cells Inject virus particles into inner ear New hair cells
grow near Organ of Corti! Research in Guinea Pigs Cure for Deafness
?
- 44. Confidential HSV1causescoldsores. Whenengineeredas
Seprehvir(HSV-1716),itis harmlesstohealthy@ssue. Oncolytic viruses
Infect and kill cancer tumour cells No damage to healthy tissue
Evidence of impact in clinical trials Able to deliver new genes
into cancer cells Micro-dose chemo, micro-dose radiotherapy Viruses
to cure cancer
- 45. ElectronicMedical Recordswillmean beerdecisions
usingBigData
- 46. ! ! ! Product scanning means safety ! Computer-aided
decisions save lives and time
- 47. Ottawa Hospital, Ontario - 3000 ipads Mayo Clinic - 2000
ipads !
- 48. Zettabyte = 1024 Exabytes Exabyte = 1024 Petabytes Petabyte
= 1024 Terabytes Terabytes = 1024 Gigabytes That's a data explosion
of 44x in ! Big Data
- 49. Genescreening willdominate disease preven6on
- 50. Genetic Prophecy
- 51. Genes for old age, speech, memory, criminality, depression,
obesity and stable relationships
- 52. Fluidics Biochemistry Semiconductors Genetics Mathematics
Immunology Robotics Read genome in 2 hours for $5,000
- 53. OrganRepair willberou6ne usingowncells
- 54. Stem Cells
- 55. Pigs teeth grown inside rats Mice grow new teeth from nerve
cells / gum tissue Grow New Teeth
- 56. Repair of heart, retina, brain or spinal cord using adult
stem cells Repair Heart / Brain
- 57. Competition in spinal cord damage from chips implanted into
brain
- 58. New insulin cells in capsules to protect from immune system
Repair Pancreas to treat diabetes
- 59. 79 Competition from implanted devices containing
insulin
- 60. Print Elastomere
- 61. We can print layers of living cells....
- 62. Print New Skin (Lexmar)
- 63. Lifeexpectancyin mostna6onswill increasebyfar morethan1week
everymonth
- 64. Performance Shift in retail health care from health
treatment to life enhancement
- 65. Want to look better
- 66. may be Want to think better...... 20%studentsinUSusememory-
enhancingdrugstopasstheirexams
- 67. An6-Ageingwill beaglobal obsession-with rapidprogress
- 68. Can we stop ageing ?
- 69. 7mechanismsofageinginanimalandhumancells
Celllossoratrophywithoutreplacement
Oncogenicnuclearmuta6onsandepimuta6ons Mitochondrialmuta6ons
Cellsenescence(deathresistant) Intra-cellularjunk
Extra-cellularjunk(aectscells)
Randomextra-cellularcross-linking
- 70. Worn out Mitochondria Energy Boost R-alpha-lipoic
acidAcetyl-L-carnitine
- 71. Adenovirus Infected mouse hair cells Permanent colour
change Permanent Hair Colour
- 72. Treatment which restores and maintains the youthful
elasticity of hardened arteries and helps wrinkled skin. Global
sales? Low blood pressure and total body lift ! ! ! ! ! !
Alteon
- 73. Monkeys on diet live longer After 20 years - 80% alive v
50% on normal calories Less cancer, diabetes, heart disease,
strokes, brain decay 96
- 74. Slow or no ageing is a reality Rockfish, Turtles, some
Whales ! No signs of getting old Rougheye rockfish (Sebastes
aleutianus) 205 years Aldabra Giant Tortoise 255 years Lobsters are
believed to live 100 or more years Ocean Quahog clam 405 years Some
animals do not seem to age in normal way
- 75. Manyhealth costswillfall whiletotal spendingwillrise
- 76. Faster healing
- 77. Negative Pressure Healing
- 78. Adenoviral human telomerase reverse transcriptase
- 79. Fundingof HealthCarewill besensi6ve poli6calissue
- 80. Patent Expiry3000 Canadian Pharma Patents 2003-11! ! ! ! !
! !
- 81. Ra6oningof healthcarewill beseenin everyna6on
- 82. Irrational Rationing
- 83. Rationing all government Health competes with ....
Specialties compete Diseases / Patient groups Treatment methods
Greatest impact for greatest number Competition
- 84. Transurethral resection Laser destruction Microwave
destruction Heat destruction Da Vinci robot Competition
- 85. Patient campaigns / Google Legal / IT linked decisions
Financial incentives Patient experience /quality life Local skills
/ experience Appropriate infrastructure Impact on rationing
- 86. Expectrapidgrowth globallyinprivate medicalcare,health
insuranceand medicaltourism
- 87. Expectmanynew ethicalchallengese.g. beginningandendof
life,dataprivacy,who ownsgenes,gene6c discrimina6on
- 88. Oneofgreatest ethicalchallengeswill beimprovingaccess
tohealthcarein poorestna6ons
- 89. 1 in 12 in Liberia UNICEF 1 in 10 women die in childbirth
in some parts of Northern Mozambique
- 90. 115 1.8 million small children die every year because of
dirty water supplies
- 91. In a global village, every local health problem can have a
global impact - so expect more global health initiatives
- 92. ! ! Crea6ngaBeerWorld Expectrapidinnova6oninmedical
technologywithmanystartupsandhealth
productslaunchedbytechnologygiants-
withmajorinvestmentinSKorea
- 93. globalchange.com - slides and videos Future of Health
Care