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Dr Vijay Marakala
Biochemistry
SIMS & RC
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Metabolism
Sum of all the chemical transformations taking place in a cell or organism,
occurs through a series of enzyme-catalyzed reactions that constitute
metabolic pathways.8/16/2013
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Precursor Intermediates Product
Metabolite
s 8/16/2013
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Intermediary metabolism
Combined activities of all the metabolic pathways that interconvert precursors, metabolites, and products
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CatabolismAnabolism
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CatabolismAnabolism
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Methods of study of Intermediary metabolism
Use of whole organisms or its components
Use of metabolic probes
Use of isotopes
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Use of whole organism or its components
Whole organism
Isolated organs
Organ slices
Intact cells8/16/2013
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Methods of study of Intermediary metabolism
Use of whole organisms or its components
Use of metabolic probes
Use of isotopes
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Utility of metabolic probes
Inhibitors Mutants
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