Galenicals ahd kerala

Dr. D. Sanjay MVSc, NDPVM, PGDOH

Multidisciplinary field of inquiry investigating the anthropological rationale and the pharmacological basis of the medicinal use of plants, animals, fungi, micro-organisms, and minerals by human cultures

(Rivier L., Bruhn J. G. (1979). Editorial. J. Ethnopharmacol. 1 110.1016/0378-8741(79)90013-8 )

Inventory by WHO found around 20,000 plant species in use for medicinal purpose in various countries.

Only 250 of those species are commonly used or have been checked for main active chemical compounds.

Cheaper drugs

Lesser side effects

Lesser residual effects.

52 Common drugs tendered

Roughly 60% of budget

Acid Benzoic IP 500gm

Acid Boric IP 500gm

Acid Salicylic IP 500gm

Ammo Carb IP 500gm

Ammo Chlor IP 500gm

Copper SulphateIP 500gm

Creta Preparata IP 1kg

Dried Ferrous Sulphate IP 500gm

Ext.Glycerrizha IP 500ml

Glycerine IP 500gm

Iodine Crystals IP 125gm

Iodoform IP 100gm

Light Kaolin IP 1kg

Light Liquid Paraffin 500ml

Lint.Camphor IP 500ml

Lint.Turpentine IP 500ml

Liq.Picis Carbonis IP 500ml

Magnesium Carbonate IP 500gm

Magnesium Sulphate IP 25kg (1kg packets x 25 in each bag)

Oil Eucalyptus IP 500ml

Paraffin Mole album IP 5kg

Potassium Iodide IP 500gm

Pottasium Permanganate IP 500gm

Pulv.Ajowan IP 2kg

Pulv.Anisi IP 2kg

Pulv.Camphor IP 2kg

Pulv.Chiretta IP 2kg

Pulv.Gentian IP 2kg

Pulv.Glycerrizha IP 2kg

Pulv.Nuxvomica IP 2kg

Pulv.Zingiberis IP 2kg

Sodium Bicarbonate IP 1kg

Sodium Salicylate IP 500gm

Sodium Thiosulphate IP 500gm

Spt. Ammonia Aromaticus IP 500ml

Sulphur sublimatum IP 500gm

Tr.Asafoetida IP 500ml

Tr.Benzoin IP 500ml

Tr.Calumba IP 500ml

Tr.Cardamom IP 500ml

Tr.Catechu IP 500ml

Tr.Chiretta IP 500ml

Tr.Iodine IP 500ml

Tr.Nuxvomica IP 500ml

Tr.Picrorhiza IP 500ml

Tr.Zingiberis IP 500ml

Acriflavin IP 100gm

Zinc Oxide IP 500gm

Individual Drug details(based on common drugs standardized for purchase by AHD

Category wise Drugs

Formulations

Acid Benzoic IP 500gm

MOA – Inhibition of Glycolysis(ATP)

Externally

Antiseptic, Parasiticide & Antifungal

Internally

Urinary antiseptic

Anti rheumatic

Dose

Cattle – 4 to 15 gm ….Dogs - 0.3 to 0.6g

Toxicity – Skin Irritation, Allergy

Antiseptic

1 – 10 % in Paraffin molle album

2% solution is used as non irritant coliyrium.

Can be used as pessary (10% ointment).

Boro Glycerine – 3: 4 ratio used as mouth

dressing in F & M;

Melboracis – Borax – 10 Glycerine – 5,

Honey – 85

COX INHIBITOR Externally

1. Keratolytic 2. Parasiticide 3. Antiseptic (Lotion – Salicylic Acid 2gm with 1 gm Castor oil in 100

ml of 95% Alcohol) Internally

1. Antirheumatic 2. Antipyretic 3. Antizymotic 4. Diuretic 5. Urinary antiseptic

Dose Cattle – 8 to 15gm Goats - 1 to 3 gm Dogs - 0.3 to 1 gm

Incompatible with spt. aethoris nitrosi, iron salts, Spt. ammo. aromaticus

Ammo Carb IP 500gm

Smelling salt

MOA -Mixed acting expectorant- stimulates tracheobronchial glands by irritation, gastropulmonary vagal reflex

Induce broncho dilatation & cough

1. Expectorant 2. Carminative & Rumenotoric

Dose

Cattle - 15 to 30g Goats - 0.6 to 2g Dogs - 0.12 to 0.6g

3. Respiratory, Cardiac and Intestinal stimulant

4. Stimulant 5. Diuretic 6. Antacid 7. Counter irritant

Dose - Cattle - 16 to 60gm

Ammo Carb IP 500gm

Ammo. Carb +

Nuxvomica in atony of rumen

Ammo Chlor IP 500gm

MOA

Mixed acting expectorant- stimulates tracheobronchial glands, gastropulmonary vagal reflex

Irritate Mucous membrane – Induce broncho dilatation & cough

Increase calcium level in blood

1. Refrigerant

2. Diuretic (Maximum dose may be given to relieve ascites)

3. Cholagogue (in jaundice in dogs)

4. Acidifier of blood

Ammo Chlor IP 500gm

Acidifier of urine (urinary calculi in cattle)

Dose

Cattle – 15 gm

Goats - 1 to 2gm

Dogs - 0.12 to 0.6 gm

Prevention of Hypocalcaemia

50 gm/day two weeks prior to Calving in cows to activate Parathormone

(Anonymous) – Needs further confirmation before use.

Ammo Chlor IP 500gm

Copper Sulphate IP 500gm

Blue vitriol, Blue stone

1. Anthelmintic (used as 1% solution)

Dose: Cattle 2 – 12 gm

Goat -0.25 to 1gm

Dogs – 0.25 to 1 gm

EMETIC DOGS

Act directly on GIT through local irritant effects,

Indirectly, through their effects on the CTZ

1 -3 % - 10 – 30 ML DEPENDING UPON SIZE OF DOG

0.2 -0.6 gm Oral

Copper Sulphate IP 500gm contd….

3. Haematinic

Dose: Cattle: 0.3 to 0.6 gm

Dog – 1 mg to 6 mg

4. Intestinal Astringent

Cattle – 2 – 12 gm

Dogs – 50 – 100 mg

5. Caustic : (Powder or 20% solution) - To reduce exuberant granulation

Copper Sulphate IP 500gm contd…. 6. 1- 5% solution - Closure of oesophageal groove in

ruminants.

5% copper sulphate or 10% sodium bicarbonate can be administered at doses of 60ml to cattle to bring about closure of oesophageal groove.

Onset of reflex response takes about 5-10seconds and the groove may remain closed for up to 60 seconds.

Copper Sulphate IP 500gm

contd…. 7. Antiseptic :- 0.5% solution is used as collyrium

(1 to 3% solution is used in vaginitis, urethritis & dermatophytosis)

8. Antidote to phosphorus poisoning - 2 gm oral initially then repeat if symptoms doesnot subside

Tried in Dermatophylosis/ORF

cases

2% Copper sulphate

plus 2% formalin

after removal of scabs supported with streptopenicillin

Copper Sulphate IP 500gm

contd…. TOXICITY

Nausea, vomiting occur

within minutes followed by abdominal pain and diarrhoea.

Secretions may be blue/green.

Severe gastrointestinal irritation

Intra vascular haemolysis

Symptomatic methaemoglobinaemia may be reversed by the intravenous administration of 2 mg/kg methylene blue (as a 1 per cent solution over five minutes).

Purgatives

Gastric lavage

Dried Ferrous Sulphate IP 500gm

1. Haematinic

2. Intestinal astringent

Dose

Cattle: 4 to 8 gm

Goat – 0.3 to 1.5 gm

Dog – 30 to 120 mg Incompatible with alkalies & their carbonates

Ext.Glycerrizha IP 500ml Glycerhiza glabra

Root used

Popular flavouring agent

Active ingredient – Glycerhizin

ACTION/ISES

Expectorant

Demulscent

Laxative

Creta Preparata IP 1kg

Externally

1. Desicant(Hygroscopic)

Internally

2. Astringent & protective

3. Antacid

4. Feeble & slow acting antiseptic

5. Absorbent

Calcium Carbonate

Chalk

For Udder Oedema

Vinegar 50 ml

Creta 50 gm

Creta Preparata IP 1kg

Dose

Cattle – 60 to 125 gm

Goat – 8 to 15 gm

Dog – 0.5 to 2 gm

Light Kaolin IP 1kg

Aluminium silicate

1. Desicant

2. Intestinal astringent

3. Adsorbent of toxins

4. Excipient

Dose

Cattle – 30 to 60 gm

Goat – 15 to 30 gm

Dog – 0.6 to 1.3 gm

Glycerine IP 500gm contd….. 1. Sweetening agent : Can be used as a

substitute for syrup.

2. Demulscent : Administered in cough electuaries.

3. Laxative

Per rectum as enema

In Cattle – 200 ml

In Dogs - 15ml.

Administer with 1/3 volume of water

Glycerine IP 500gm

4. With Boric Acid - FMD lesions in oral cavity

5. With Mag Sulph as paste -Relieves edema

Form a film over the skin, acts by preventing evaporation of moisture from skin and by restoring softness & elasticity.

Iodine Crystals IP 125gm

Antiseptic

Dressing Powder

Iodoform IP 100gm

Antiseptic,

Deodorant,

Stimulant to granulation,

Local anaesthetic

Light Liquid Paraffin 500ml

Mineral oil

Externally

Emollient, Protective, Lubricant, Vehicle

Internally

Laxative

DOSE

Cattle - 0.6 to 1.2 lit.

Goats – 150 to 300ml.

Dogs – 4 to 30ml.

Prevents absorption of nutrients

Lint. Camphor IP 500ml

Counter irritant/Rubefacient

Antiseptic

Stimulation followed by sedative effect on peripheral nerve endings

Lint.Turpentine IP 500ml

Counter irritant

Liq.Picis Carbonis IP 500ml

Ol.Picis liquidum/Coal Tar

Erosion of Hoof in Cattle

Can be mixed with Zinc Oxide and Copper sulphate made as a paste and used for Foot Dressings

Copper Sulphate – 3 gm

Zinc Oxide – 25 gm Liq Picis Carbonis – 100 ml

Oil Eucalyptus IP 500ml

Externally

1. Antiseptic

2. Disinfectant

3. Rubefacient

4. Antizymotic

5. Parasiticide

Internally

1. Pulmonary Antiseptic and Expectorant(inhalation in inflammations of respiratory tract)

2. Urinary antiseptic and stimulant to the tract(C/C cystitis/nephritis)

3. Antipyretic

DOSE: Cattle – 4 to 15 ml Goat: 0.6 to 1 ml Dogs: 0.03 to 0.2 ml

Magnesium Carbonate IP 500gm 1. Antacid

2. Laxative

DOSE

Cattle - 2 to 12 gm

Goats – 0.5 to 2 gm

Dogs – 0.3 to 2 gm

Incompatible with acidic substances

Magnesium Sulphate IP 25kg

(1kg packets x 25 in each bag)

Epsom salt

1. Saline Purgative

2. Laxative & Febrifuge

3. Diuretic

4. Chologogue action

DOSE

Cattle - 250 to 350 gm

Goats – 60 to 125 gm

Dogs – 4 to 12 gm

Magnesium Sulphate contd….. 4. Indirect cholagogue

(Cause contraction of gall bladder)

DOSE

Cattle - 30 to 60 gm

Dogs – 0.6 to 1.3 gm

Magnesium Sulphate contd….. 5. Alterative(Skin infections)

6. Analgesic, Externally.

7. Antiseptic, Externally.

8. Antispasmodic(Tetanus)

9. Super saturated sol. I/V for euthanasia (Not recommended)

10. Muscle relaxant 10% solution -s/c – Dose in Cattle – 8 – 16 gm.

11. 0.25% solution has gluconeogenic effects – Can be used in Ketosis.

Magnesium Sulphate contd….. Mg Sulph - Glycerine paste for Oedema

20 grams of magnesium sulphate diluted in 100 ml of glycerine

Incompatible with sodium and potassium carbonates, lead acetate & lime water

Paraffin Mole album IP 5kg

White Vaseline

1. Basis for ointment

2. Lubricant

3. Protective : May be applied or eroded teats, eczema etc.

Potassium Iodide IP 500gm

Similar to iodine except that it is less irritant to Gl tract. So used for administration through mouth.

1. Expectorant Dose

Cattle -7 to 15gm Goats - 1 to 3g Dogs - 0.2 to 0.6gm

2. Fibrolytic

3. Antiseptic

4. Rubefacient

5. Absorbent & counter irritant

Potassium Iodide …contd….. 6. Alterative

7. Blood antiseptic

8 Stimulant to thyroid, lymphatic and sweat glands

9. Vesicant

In compatible with alkaloids, mineral oils, Spt. Aethoris nitrosi, substance containing starch.

Should not be used in acute inflammatory conditions of respiratory tract.

Pottasium Permanganate IP

500gm

Oxidizing agent

Antiseptic

Disinfectant

Deodorant

Caustic

Pottasium Permanganate IP

500gm contd…… NEVER TOUCH WITH HAND

USE

1 in 1000 solution is used as wound and mouth lotion

5% solution is used as foot bath to reduce excess granulation

Pottasium Permanganate IP

500gm contd…… Dose

Cattle -1.75 to 3.5gm

Goats - 0.6 to 2g

Dogs - 0.06 to 0.18gm

Fumigation with Formalin

For 1000 Cu.feet

450 gm of KMNO4 plus 500 ml formalin

Equal parts in different bowls

Pulv. Ajowan IP 2kg

Trachyspermum ammi

Ayamodakam

Active Ingredient – Thymol

Carrom Seeds

Seeds used

Intestinal Antiseptic

Expectorant

Ajowan……. Dose

Cattle - 30gm

Anisi

Pimpinella anisum(anise seed)

Perinjeerakam

Pulv.Anisi IP 2kg

1. Parasiticide

2. Expectorant : used in cough powder for cattle

3. Carminative

4. Alterative

Dose

Cattle - 30 to 60 gm

Goats - 5 to 12gm

Dogs - 0.6 to 2 gm

Camphor Cinnamomum camphora,

Obtained by steam distillation of wood chips.

Pulv.Camphor IP 2kg

Externally

1. Antiseptic

2. Rubefacient

3. Stimulation followed by sedative effect on peripheral nerve endings.

Internally

1. Antispasmodic

2. Carminative

3. Expectorant

4. Antipyretic

5. Intestinal astringent

Dose

Cattle – 10 gm Dogs – 0.12 to 0.6 gm

Pulv.Chiretta IP 2kg

Dried Plant of Andrographis paniculata(Kiriyath)

Native to India and Sri Lanka.

Widely cultivated in Southern and Southeastern Asia, where it has been traditionally used to treat infections and some diseases

official in B.P and U.S.P.

Bitter stomachic & Febrifuge

Dose

Cattle – 15 to 30 gm

Dogs – 0.3 to 0.6gm

Pulv.Gentian IP 2kg

Gentiana kurroo

Root used

Bitter stomachic

Dose

Cattle – 30 to 60 gm

Goats - 3.5 to 7 gm

Dogs – 0.3 to 1.3 gm

Incompatible with Iron sulphate, Silver nitrate & Lead salts.

Pulv.Glycyrrhiza IP 2kg

Pulv Liquorice

Glycerhiza glabra Root used

Popular flavouring agent

Active ingredient – Glycerhizin

Expectorant, Demulscent, Laxative

Pulv.Glycyrrhiza IP 2kg DOSE

Cattle – 30 to 60 gm

Goats – 4 to 12 gm

Dogs - 0.12 to 0.6 gm

Nuxvomica Strychnos nux-vomica tree

Ripe Seed Used

Alkaloid – Strychnine & Brucin

1. Stomachic, Intestinal stimulant

2. Nervine tonic

3. Respiratory & cardiac stimulant

4. Expectorant

SEED AND BARK

Pulv.Nuxvomica IP 2kg

DOSE

Cattle – 4 to 8 gm

Goats – 0.6 to 2.5 gm

Dogs - 30 to 200 mg

Contra indicated in Pregnancy

Tr.Nuxvomica IP 500ml

1. Stomachic, Intestinal stimulant

2. Nervine tonic

3. Respiratory & cardiac stimulant

4. Expectorant

DOSE

Cattle – 30 ml.

Goats – 1 to 4ml.

Dogs - 0.12 to 0.6ml

TOXICITY OF NUX VOMICA

Both strychnine and brucine are typical antagonists of the glycine receptors on postsynatic membrane.

Toxic effects mainly cause central excitation

Autopsy findings mainly include pathological changes caused by acute disorder of blood circulation, characterized by the congestion and edema of organs or pinpoint bleeding of mucosa or serous membrane

Pulv.Zingiberis IP 2kg

1. Powerful aromatic stimulant

2. Sialagogue

3. Stomachic

4. Carminative

5. Corrective

DOSE

Cattle – 30 to 60 gm

Goats – 3.5 to 7 gm

Dogs - 0.6 to 1.3 gm

Sodium Bicarbonate IP 1kg

Baking Soda

1. Mild Sedative to skin (1% solution)

2. Antacid

3. Stomachic

4. Expectorant

5. Useful in jaundice as it thins the bile

6. Can be used in rheumatism along with sodium salicylate

Sodium Bicarbonate IP 1kg DOSE

Cattle – 15 to 30 gm

Goats – 2 to 10 gm

Dogs - 0.3 to 1.5 gm

Incompatible with acids and acid salts, heavy metals and alkaloidal salts.

Sodium Salicylate IP 500gm

1. Antipyretic

2. Anti rheumatic

3. Urinary antiseptic

4. Analgesic

5. Hepatic stimulant

Sodium Salicylate IP 500gm

DOSE

Cattle – 8 to 15g …….. 60 to 125g(Urinary Antiseptic,

Analgesic)

Goats – 2 to 10 gm

Dogs - 0.3 to 1.5 gm

Incompatible with acids and iron salts.

Sodium Thiosulphate IP 500gm

Hypo

Externally

1. Deodorant

2. Anti fungal

3. Antiseptic

10% solution or ointment is useful in mange, ring worm and eczema , malasesszia

HYPO CONTD…. Internally

4. Antizymotic

5. Antidote to Arsenic, Antimony, Bismuth, Mercury and other metallic and metalloid poisoning.

6. Useful in HCN poisoning

500 mg/kg as 20 % W/V, IV, plus 30 g/cow, PO, to detoxify any remaining HCN in the rumen. Repeat if necessary.

MOA - Injection of sodium thiosulfate provides sulfur to convert cyanmethaemoglobin to the non-toxic thiocyanate, which is excreted in the urine

HYPO CONTD…. DOSE

CATTLE - 30 to 60 gm ORAL

GOATS - 15 to 30 gm ORAL

DOGS – 0.3 to 1 gm ORAL

Spt. Ammonia Aromaticus IP 500ml

Carminative(irritant action)

Expectorant(irritant action)

Diaphoretic

Antacid

DOSE

CATTLE - 30 to 120ml

GOATS -4 to 16ml

DOGS - 1.3 to 4ml

Spt. Ammonia Aromaticus IP

500ml contd….. Can also be used for

inhalation for cardiac and respiratory stimulation

Spiritus ammo aromaticus due to its irritant action can be used in carminative mixture with Cardamom tincture

Anti Rheumatic)Counter irritant)

Sulphur sublimatum IP 500gm

1. Insecticide

2. Parasiticide

3. Antifungal

4. Disinfectant

Used as Skin Ointment

Asafoetida

Ferula asafetida

Resin-like gum from the dried sap extracted from the stem and roots

Used as a spice.

Resin is greyish-white when fresh but dries to a dark amber colour.

Tr. Asafoetida IP 500ml

1. Irritant

2. Carminative

Dose

Cattle – 15 to 60ml.

Goat - 1.2 to 3.5ml

Dogs - 0.6 to 1.3ml.

3. Nauseant

Paint Tr. Asafoetida on the bandage to prevent the dogs from gnawing off the bandage.

Application prevents feather pulling in poultry.

Tr.Benzoin IP 500ml

1. Antiseptic (Alcohol content)

2. Stimulant( May be injected into sinuses and Fistulae)

3. Haemostyptic(act as a adhesive )

Tr. Calumba IP 500ml

Jateorhiza palmata

Bitter stomachic

Indigestion/Anorexia

Official. U.S.P

East African Plant

Dose

Cattle – 30 to 60ml.

Goat – 3.5 to 7 ml

Dogs - 2 to 4 ml.

Calumba

It stimulate the gustatory nerves - reflex stimulation of gastric juice - increase gastric circulation and promote digestion and absorption.

Anti Emetic ….(action as above)

Tr. Cardamom IP 500ml

1. Stimulant

2. Stomachic

3. Carminative

Dose

Cattle – 30 ml

Goat - 4 to 10 ml

Dogs – 1.3 to 4 ml.

CATECHU

Areca Catechu

Betel Nut

Tr.Catechu IP 500ml

Alcoholic extract of leaves and young shoot of Areca catechu

1. Intestinal astringent

2. External astringent

Dose

Cattle – 15 to 60ml.

Goat - 5 to 20 ml

Dogs - 2 to 4 ml.

Tr.Chiretta IP 500ml

Dried Plant of Andrographis paniculata

Bitter stomachic

Febrifuge

Dose

Cattle – 30 to 60ml

Dogs – 2 to 4ml

Tr.Iodine IP 500ml

Antiseptic

Feather Pecking

Iodine solution (15 drops of the tincture in a glass of water) effective for precipitation of lead, mercury, silver and certain alkaloides of quinine and strychnine.

Followed by Mag Sulph

Tr.Picorrhiza IP 500ml

Picrorhiza kurroa

Root

Bitter stomachic

Same as Gentian

Liver disorder

Anti pyrectic

DOSE

Cattle - 30 to 60ml.

Goat - 2.5 to 10ml.

Dog - 0.3 to 2ml.

Tr.Zingiberis IP 500ml

1. Powerful aromatic stimulant

2. Sialagogue

3. Stomachic

4. Carminative

DOSE

Cattle - 30 to 60ml.

Goat - 2.5 to 10ml.

Dog - 0.3 to 2ml.

Acriflavin IP 100gm

1. General Antiseptic

2. Active in pus containing wounds

1 in 1000(0.1%) to 1 in 2000 solution or as ointment is used.

For irrigation of udder 1 in 5000 to 1 in 10,000 solution is used.

For destruction of udder 1 in 400 to 1 in 500 is used.

2. Urinary Antiseptic

Zinc Oxide IP 500gm

1. Astringent

2. Desiccant

3. Antiseptic

Liq. Formaldehyde / Formalin I.P.

500 ml

Externally

1. Parasiticide(2% formalin solution – Ring worm)

2. Antiseptic(20% formalin - Sinuses and fistulae)

3. 2% Formalin plus 2% copper Sulphate used for Dermatophilosis

4. Preservative(10%)

5. Foot Bath – 1%

Liq. Formaldehyde / Formalin I.P.

500 ml contd….. Internally

1. Intestinal antiseptic

2. Antizymotic (Diluted formalin)

Dose - CATTLE – 8 to 30 ml

3. Blood antiseptic(i/v) – (Mastitis, Pneumonia)

Fumigation with Formalin

For 1000 Cu.feet

450 gm of KMNO4 plus 500 ml formalin

Equal parts in different bowls

EU SOL

Bleaching Powder 1.25 gm

Boric Acid – 1.5 gm

Aqua ad – 100 ml

Used as Disinfectant & Antiseptic

CASTOR OIL

1. Mild purgative (internal)

2. Mild astringent(externally)

3. Soothening agent (eye) – foreign body/caustics

DOSE

CATTLE - 0.5 to 1litre

CALVES - 50 to 100 ml

DOGS - 8 to 50ml…. 5ml for Pups

STARCH

1. Basis : basis for dressing powder

2. Deodorant(Rub on the hands to remove foul odour, when you have handled putrid materials, Eg:- retained placenta)

3. Protective and absorbent( Starch 10 parts with Boric acid 1parts may be applied on weeping eczema & superficial burns.

4. Demulscent: Starch gruel, starch water.

Starch in water 1: 40 is useful in diarrhea, dysentery.

5. Antidote : In iodine poisoning.

HYDROGEN PEROXIDE

1. Antiseptic

2. Disinfectant

3. Styptic

10% solution is used for cleaning sinuses and fistulous tract.

Can be used to clean ear only if there is too much debris or pus.

GARLIC Carminative

Alterative

Expectorant

Emmenagogue

Dose – 8 to 15 gm

Antiseptic – Boil 2 pieces of garlic in 15 ml gingelly oil….Apply in Otorrhoea

BLACK PEPPER Carminative

Stomachic

Anti Spasmodic

DOSE

Cattle – 15 to 30 gm

Dogs – 0.12 to 0.6 gm

Expectorant

Anisi

Liquorice/ Glycyrrhiza

Potassium Iodide

Ammonium carbonate

Eucalyptus oil

Garlic

Camphor

Asafoetida

Sodium bicarbonate

Ajowan

Nux Vomica

Diuretic

Ammonium chloride

Ammonium carbonate

Potassium Iodide

Magnesium sulphate

Carminatives

Spt. Ammoniae. Aromaticus

Asafoetida

Spt. Aethoris Nitrosi

Ammonium carbonate

Tr. Cardamom Co.

Corriander(30 - 60 gm for cattle)

Anisi

Oil of turpentine

Black Pepper

Camphor

Asfoetida

Stomachic

Nux Vomica

Calumbae

Gentian

Chiretta

Cardamom

Ginger

FORMULATIONS

WHITE FILED OINTMENT

Antifungal

Benzoic acid - 2g (6%)

Salicylic acid - 1 g (3%)

Paraffin mole album - 300 g

Dressing Powder

Iodoform - 2 g

Boric acid - 30 g

Zinc oxide - 120 g

Iodine ointment

Rx

Iodine Crystals 1 gm, (4 parts)

Pot Iodide 1 gm, (4 parts)

Glycerine 3ml (12 parts)

Vaselin 20 gm (40 parts)

Iodine is antiseptic, Parasiticide, counter irritant, stimulant to wounds

Pot Iodide is added to increase solubility

Glycerine emollient, protective, basis and dissolves Iodine and KI

ANTISPETIC PASTE

ZIPP

Zinc Oxide

Iodoform aa 4 gm

Liquid paraffin QS

Mft. Paste sig Apply externally

SULPHUR ONTMENT

Sulphur Sublimed – 10 parts

Paraffin mole album – 90 parts

Mft. ung sig For external application

IODINE OINTMENT

Rx

Iodine – 4 parts

Pot. Iodide – 4 parts

Glycerine – 12 parts

Paraffin mile album – 80 parts

Mft. ung sig For external application

Ear Dressing Powder

Iodine - 350 mg

Pot. iodide - 650 mg

Boric acid - 30 g

Sulphanilamide - 30 g

Linimentum album

(White liniment)

Acetic acid - 8.5 ml

Oil of eucalyptus - 40 ml

Yolk and white of egg - 10 ml

Aqua ad - 41.5 ml

DUSTING POWDER Dusting Powder of Zinc Oxide and Boric acid

Zinc oxide - 50 gm

Boric acid - 50 gm

Udder SKIN Necrosis

Equal parts of Tr. Iodine and Formalin can be applied

Mistura Alba (White Mixture)

Magnesium sulphate - 27.4 g

Magnesium carbonate - 4.57 g

Aqua ad - 100 ml

Dose

Dog & Cat - 8.30 ml

Peppermint oil(20%) can be add - Anti spasmodic, carminative, flavouring agent

Lugols Iodine

5% w/v of iodine

10% w/v of Kl in distilled water.

Dose : Horse 8-15 ml. Dog 0.1 – 0.5 ml.

USE

Metritis/Cervicitis - Intra Uterine- -20 ml

Cattle - I/V for Infectious diseases– 20 to 40 ml

Dogs - I/V for Infectious diseases– 1 to 5 ml

STOMACHIC

CATTLE

Rx

Sod. Bicarbonate

Pulv. Gentian

Pulv. Zingiberis aa 15 gm

Mft. Pulv. 1; Mitte talis 12 Sig : 1 powder twice daily

STOMACHIC

CATTLE

Rx

Pulv. Zingiberis

Pulv. Gentian aa 12 gm

Sod. Bicarbonate

Pulv. Chiretta aa 15 gm

Pulv. Nux vomica 6 gm

Mft. Pulv 1; such 8 Sig: 1 powder twice a day

STOMACHIC CATTLE

Rx

Sod. Bicarbonate

Sod. Chloride aa 15 gm

Pulv. Nux vomica 4 gm

Mft. pulv. 1; such 12 Sig: 1 powder twice daily

STOMACHIC CATTLE

Rx

Pulv. Nux vomica 8 gm

Ammo. Carbonate

Pulv. Gentian

Pulv. Zingiberis aa 15 gm

Mft. 1 dose, such 12 Sig: 1 powder bid.

-

STOMACHIC CATTLE

Rx

Mag. Sulphate - 200 gm

Sod. Chloride - 125 gm

Pulv. Zingiberis - 30 gm

Sod. Bicarbonate - 30 gm

Aqua - 560 ml

Mft. mist, sig: 1/2 bid

STOMACHIC CATTLE

Rx

Pulv. Nux vomica

Ammo. Carbonate aa 4 gm

Pulv. Ginger

Pulv. Gentian

Pulv. Chiretta aa 30 gm

Mft. pulv. 1; such 6 Sig: once daily for 6 days

STOMACHIC CATTLE

Rx

Sod. Bicarbonate

Sod. Chloride aa 25 gm

Pulv. Nux vomica 5 gm

Pulv. Gentian 15 gm

Mft. pulv., sig. stat

STOMACHIC CATTLE

Rx

Tr. Nux vomica - 25 ml

Tr. Calumba - 360 ml (Bitter stomachic)

Tr. Zingiberis - 50 ml

Aqua ad - 750 ml

Mft. mist, sig. 1/6 bid before feed.

Tr. Picorrhiza 30 ml(single dose) can be used in stomachic mixture to substitute Calumba

STOMACHIC CATTLE

Rx

Sod. Bicarbonate - 30 gm

Spt. Ammo. Aromaticus - 30 ml

Tr. Nux vomica - 10 ml

Tr. Zingiberis - 10 ml

Aqua - 250 ml

Mft. haust, sig. now

-

STOMACHIC and TONIC Rx

Pulv. Nux vomica - 8 gm Mag. Sulphate - 60 gm Ferri Sulphate - 4 gm Pulv. Gentian - 15 gm Mft. 1 dose, such 12 Sig: 1 pulv. bid

TONICS CATTLE

Rx

Ferri. Sulphate - 40 gm

Mag. Sulphate - 600 gm

Pulv. Gentian - 150 gm

Pulv. Nux vomica - 40 gm

Mft. pulv, sig: 1/12 bid with treacle.

TONICS CATTLE

Rx

Sod. Bicarbonate

Sod. Chloride aa - 30 gm

Pulv. Nux vomica - 4 gm

Pulv. Gentian - 8 gm

Mft.pulv.1, such 12 Sig: 1 powder bid with treacle

TONICS CATTLE

Rx

Ammo. Carbonate – 80 gm

Pulv. Nux vomica – 40 gm

Pulv. Gentian

Pulv. Zingiberis aa – 150 gm

Mft. pulv., sig: 1/10 bid with treacle

TONICS CATTLE

Rx

Ferri. Sulphate – 4 gm

Pulv. Gentian

Pulv. Anisi aa – 8 gm

Mft. pulv. 1, such 12 Sig: 1 dose daily in feed.

TONICS CATTLE

Rx Copper Sulphate - 2 gm

Ferri. Sulphate - 20 gm

Pulv. Nux vomica - 40 gm

Pulv. Gentian - 80 gm

Sod. Bicarbonate - 80 gm

Mft. pulv., sig: 1/10 bid

TONICS CATTLE

Rx

Ferri. Sulphate -

Pulv. Nux vomica -

Pulv. Chiretta -

Pulv. Zingiberis aa - 15 gm

Sod. Bicarbonate - 10 gm

Mft. pulv. 1, such 6 Sig: 1 pulv. daily as elect.

Salines followed by Stimulants Salines in morning

Mag Sulph, Sod Chlor, Pulv Gentian, Pulv Zingiberis

Stimulants in the evening

Ammo Carb, Pulv Nux vomica

(Ref: Late Prof(Dr). P. O. George)

Carminative Mixture

Rx

Dogs Cattle

Soda bicarb 2 gm 30 gm

Tincture zingiberis

Spt. Ammo. aromatics aa 4 ml 60 ml

Tincture cardamom 1 ml 30 ml

Aqua ad 90 ml 1000 ml

Mft. mist. Sig. 1/3 tid. p o.

Carminative Mixture

CATTLE

Rx

Pulv. Nux vomica – 4 gm

Sod. Bicarbonate – 15 gm

Pulv. Zingiberis – 8 gm

Mft. pulv. 1, sig: such 6 Sig; 1 pulv. bid.

Carminative Mixture

CATTLE

Rx

Pulv Glycerhiza - 8 gm

Ammonium chloride - 8 gm

Treacle QS

Expectorant Good for bronchitis pharyngitis

ANTI ZYMOTICS CATTLE

Rx

Formalin - 15 ml

Aqua ad -1000 ml

Mft. mist, sig 1/2 bid

ANTI ZYMOTICS CATTLE

Rx

Formalin – 5 ml

Sod. Chloride – 120 gm

Aqua ad – 560 ml

Mft. haust, sig : stat

ANTI ZYMOTICS CATTLE

Rx

Formalin – 15 ml

Milk – 500 ml

Mft. haust, sig : stat

PURGATIVES CATTLE

Rx

Mag. Sulphate – 250 gm

Sod. Chloride – 150 gm

Tr. Zingiberis – 30 ml

Treacle – 200 gm

Aqua – 1 litre

Mft. haust, sig: now

PURGATIVES CATTLE

Rx

Mag. Sulphate – 250 gm

Pulv. Nux vomica

Pulv. Zingiberis – 15 gm

Aqua ad – 1 litre

Mft. haust, sig : stat.

ASTRINGENTS

CATTLE

Rx

Kaolin

Creta aa - 30 gm

Tr. Catechu - 30 ml

Aqua ad - 250 ml

Mft. haust, sig : now.

Tr.opi 30 ml(single dose) also has Astringent action bit not in the purchase list

ASTRINGENTS CATTLE

Rx Ferri Sulph - 4 gm

Copper Sulphate - 0.3 gm

Tr. Zingiberis - 15 ml

Tr. Catechu - 30 ml

Aqua - 250 ml

Mft. haust, sig : once or twice daily.

ASTRINGENTS DOGS

Rx

Kaolin - 1 gm

Mag. Carbonate - 1.5 gm

Sod. Bicarbonate - 1 gm

Aqua ad - 30 ml

Mft. haust, sig : now

ANTACID CATTLE

Rx

Mag. Carbonate – 15 GM

Pulv. zingiberis

Pulv. Gentian aa – 20 gm

Mft. pulv, sig : orally. as elect

ANTACID DOGS

Rx

Mag. Carbonate -1 gm

Mag. Sulphate - 2gm

Aqua -30 ml

Dose :- 8 to 30 ml.

EMETIC

DOGS

Rx

Sod. Chloride

Pulv. Mustard aa – 8 gm

Luke warm water – 60 ml

Mft. haust, sig : now.

EXPECTORANT

CATTLE

Rx

Ammo. Carbonate – 10 gm

Pulv. Camphor – 8 gm

Pulv. Zingiberis – 15 gm

Treacle – Q.S

Mft. elect, sig : orally

EXPECTORANT CATTLE

Rx

Ammo. Chloride – 15 gm

Pulv. Camphor – 10 gm

Pulv. Glycyrrhiza – 50 gm

Pulv. Anisi – 60 gm

Treacle -QS

Mft. elect, sig : 1/2 bid.

EXPECTORANT CATTLE

Rx

Ammo. Carbonate – 4 gm

Pot. Iodide -5 gm

Pulv. Camphor – 2 gm

Pulv. Glycyrrhiza – 30 gm

Treacle QS

Mft. elect, sig : 1 bid.

EXPECTORANT CATTLE

Rx

Ammo. Chloride – 5 gm

Ammo. Carbonate – 15 gm

Pulv. Zingiberis

Pulv. Glycyrrhiza aa – 30 gm

Pulv. Camphor – 8 gm

Treacle QS

Mft. elect, sig : ½ bid

CATTLE

Rx

Ferri. Sulphate – 10 gm

Cop. Sulphate – 0.5 gm

Pulv. Nux vomica

Pulv. Chiretta aa – 10 gm

Treacle QS

Mft. elect sig : 1/2 bid.

ALTERATIVES CATTLE

Rx

Mag. Sulphate – 30 gm

Sod. Bicarbonate – 8 gm

Ferri. Sulphate – 15 gm

Pulv. Anisi – 15 gm

Mft. pulv 1, such 16 Sig 1 dose bid in feed.

FEBRIFUGE CATTLE

Rx

Sod. Salicylate

Sod. Bicarbonate aa - 60 gm

Pulv. Anisi - 30 gm

Pulv. Zingiberis - 40 gm

Mft. pulv. sig : 1/2 bid as elect

FEBRIFUGE DOGS

Rx

Sod. Salicylate

Sod. Bicarbonate aa -1.8 gm

Tr. Cardamom - 1.8 ml

Syrup - 3.6 ml

Aqua ad - 50 ml

Mft. mist, sig : 1/6 every 4 hrs.

ANTI RHEUMATIC

CATTLE

Rx

Sod. Salicylate

Sod. Bicarbonate aa – 60 gm

Treacle QS

Mft. 1 dose, such 6 Sig : 1 dose every 4 hrs.

INTRA MAMMARY INFUSION

Iodine crystals – 1 gm

Pot. Iodide 15 gm

Liquid Paraffin – 1 litre

Infuse 10 – 20 ml per quarter

PHENOL - LUGOLS IODINE IN FMD

Take 5 ml distilled water

Add drop by drop 2 ml carbolic acid

Add 10 ml distilled water

Add 3 ml Lugols Iodine(freshly prepared) drop

by drop

Add more water if needed until no sediments

are present

DOSE

Cows – 20 - 25 ml IM

Heifers – 15 - 20 ml IM

Calves - 5 – 10 ml IM

References

Pharmacology - Materia Medica &

Therapeutics by Prof. V. Srinivasan

Guide Line - Veterinarians Desktop

Clinical Dairy IVA, Ernakulam

Veterinarians Clinical Dairy (89 – 90

Students Union, COVAS, Mannuthy)