29.macrolide

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Macrolides

Examples

• Erythromycin • Roxithromycin• Clarithromycin • Azithromycin

Mechanism of action

• Inhibit bacterial protein synthesis

Uses

• Atypical pneumonia caused by mycoplasma pneumoniae

• Whooping cough• Steptococcal pharyngitis, tonsillitis• Diphtheria, tetanus

Adverse effects of erythromycin

• Epigastric pain, hearing impairment, rashes, hepatitis, jaundice

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