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This is the PowerPoint version of the Video created by Dr Sanjoy Sanyal, Professor and Course Director of Neuroscience. The components of Basal Forebrain are described, followed by the Meso-limbic and Meso-cortical Pathways. Then their role in Drug Addiction and Schizophrenia are explained. Finally the Hypothalamic, Hippocampal Formation, Septal Areas and Amygdala Connections are demonstrated graphically. YouTube video has been embedded after Slide number 13, which contains a running commentary by the author on a formalinized juman brain specimen. It describes what has bee mentioned in the preceding slides. This is purely for educational purposes and no copyright infringement is intended. Tags: Basal Forebrain, Mesolimbic, Mesocortical, Drug Addiction, Schizophrenia, NAc Pathway, Hippocampal Formation, Septal Areas, Amygdala, Sanjoy Sanyal, Professor, Neuroscience,
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BASAL FOREBRAIN COMPONENTS AND
LIMBIC CONNECTIONS
Dr Sanjoy Sanyal
Professor and Course Director, Neuroscience
Basal Forebrain Components OF-PFC: Orbito-Frontal Pre-Frontal Cortex Septal Areas:
Cortical Areas: Para-terminal Gyrus (Adjacent to Lamina Terminalis) and Sub-callosal (Under Rostrum of Corpus Callosum)
Subcortical Nuclei: Between Septum Pellucidum and Anterior Commissure (Lateral, Medial, Posterior Nuclei)
Ventral Striatum: Nucleus Accumbens + Olfactory Tubercle (Cells of Calleja)
Ventral Pallidum: Substantia Innominata; Including Nucleus Basalis of Meynert
Anterior Hypothalamus: Pre-Optic Area
Orbito-Frontal PFC
Septal Areas and Connections
Ventral Striatum
Includes Nucleus Accumbens under Striatum (Fusion of Head of Caudate Nucleus with Putamen)
Also includes Olfactory Tubercle (Part of Allocortex containing Cells of Calleja in Anterior Perforated Substance)
Nucleus Accumbens
Ven
tral P
allid
um
Nucleus Basalis of Meynert
Ventral Striato-pallidal Tract
Olfactory Cortex / OF-PFC / Hippocampus
Ventral Striatum (Nucleus Accumbens +
Olfactory Tubercle)
Ventral Pallidum (Substantia innominata, which
includes Nucleus Basalis of Meynert)
Dorso-medial (Medio-Dorsal) Nucleus of
Thalamus
Septal Areas and Connections
Meso-Limbic / Meso-Cortical Tract
Meso-Limbic / Meso-Cortical Tract
Schizophrenia and Reward Pathway
Hypothalamic Afferents
Hypothalamic Efferents
Limbic Connections
Hippocampal Formation Connections
Amygdala Connections
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