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2016 3 12
1) 2) 3)
– –
Acute gout
Chronic gout
Uric Acid
Monosodium urate crystal
Purine
-
•
(Synovial fluid)
----
≠ ≠
/
• •
•
• •
( )
• ! ( )• •
( )
• – : 40– :
• –
• –
-
• ( )•
– – – – –
-
• ( )• • •
– (Intercritical Period)
• • •
– - (Tophi) – – –
• •
– –
• – – – –
• • • ( / )
NSAIDs(Non-Steroidal Anti-Inflammtory Drugs)
– – –
Ibuprofen
(Proton Pump Inhibitor)
(H2 Receptor Antagonist)
-2 (COX-2 inhibitors) –
(Colchicine ) •
– •
–
? ?
/
/
• • •
/
• •
/
• – (Allopurinol)– (Febuxostat)
• – (Probenecid– (Benzbromarone)
/
• (Allopurinol)– – –
• – –
• (Febuxostat)
/
• (Probenecid– – ( )–
• •
/
• /•
– •
–
• – BMI: (kg) ÷ (m) ÷ (m)
²< 18 5
18.5 - 22.9 23 - 24.9
25 - 29.9 > 30
• • • • •
!
www.ampoule.org.hk•
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