Stuart D. Blacksell MPH PhD RBP

Stuart D. Blacksell MPH PhD RBP

Mahidol-Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Centre for Tropical Medicine, University of Oxford, United Kingdom.

Stuart D. Blacksell MPH PhD RBP

Mahidol-Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Centre for Tropical Medicine, University of Oxford, United Kingdom.

Design and operational options for improving sustainability, biosafety, and biosecurity in

southeast Asia.

Local Challenges: building a BSL3 lab

Local Challenges: building a BSL3 lab Cont.

Local Challenges: Biosecurity engineers

Common design mistakes

Local Challenges: Other BSL3 engineering “issues”

Facilities maintenance and testing

Other considerations

• BSL3 Energy costs– Tropical climate – BSL3 single pass air = very expensive and wasteful– Why not recirculation 85% of the air with additional HEPA filtration

• Regional training faculties – Biocontainment engineering/Biosafety Officers/Maintenance– Not for profit– Use facilities and experience that is already available locally

• Assess the risks – Do we really need a BSL3 lab? – Can we use BSL2 lab with BSL3 practices

Energy conservation? (some thoughts)Energy conservation? (some thoughts)Now…Now… Future??...Future??...

AHU

AHU HEPAHEPA

HEP

A

EF EF

BSL3LAB

BSL3LAB B

SC

BS

C

Conclusions

• Focus areas for building a BSL3 lab– Standards, regulations and laws

• Know what standard (BMBL5?)

– People• Project manager (prequalify)• Biocontainment engineer (prequalify)• General contractors (prequalify)• Client (be knowledgeable)

– Documents • Specifications compliance• Budget and contingencies

Thank you