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Published by the Department of Economic Development, Jobs, Transport and Resources 1 Spring Street Melbourne, Victoria 3000 Telephone (03) 9208 3799
July 2017
© Copyright State Government of Victoria 2017 This publication is copyright. No part may be reproduced by any process except in accordance with provisions of the Copyright Act 1968.
Authorised by the Victorian Government, Melbourne.
Designed by DEDJTR Design Studio
ISBN 978-1-925629-62-0 (pdf/online)
Accessibility
If you would like to receive this publication in an accessible format, such as large print or audio, please email medtech.pharma@ecodev.vic.gov.au. This publication is also published in PDF and Word formats on http://economicdevelopment.vic.gov.au/victorian-economy-in-focus/priority-industries-sectors/medical-technologies- and-pharmaceuticals
Cover photo Staff at Grey Innovation
3 /STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
MiniFab
ContentsIntroduction 6
Key findings 7
The economic impact of the sector 10
Further information 19
Notes on methodology 20
Table 1. Summary of sector metrics 7
Figure 1. Representative sector supply chain 8
Figure 2. Key medtech and pharmaceutical business locations 9
Figure 3. Key economic aggregates for the sector (2013-14) 10
Figure 4. Total revenue generated by Victorian companies (2015) 10
Figure 5. Sector export data (goods exports only, 2016) 11
Figure 6. Annual average exports by market 2011-2016 11
Figure 7. Supply chain analysis. 12
Figure 8. Wages and employment in the sector (2013-14) 13
Figure 9. Manufacturing employment trends in the sector (2016) 13
Table 2. Company employment ranges for Victorian companies surveyed (2015) 14
Figure 10. Aggregate capitalisation of listed Victorian companies 14
Figure 11. Number of listed Victorian life science companies (2015) 15
Figure 12. Capitalisation of listed Victorian life science companies excluding Sigma Pharmaceuticals Ltd and CSL (2015) 15
Figure 13. Share of ASX market capitalisation by location of registered company offices (June 2016) 16
Figure 14. Total R&D spending by Victorian companies (2015) 17
Table 3. Outcomes by state and territory for competitive grants awarded in the 2016 application round 17
Figure 15. Victorian strengths (June 2016) 18
Figure 16. Asset development in Victoria – drugs and medical devices (June 2016) 18
5 /STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
Ministers’ ForewordWe are pleased to present the Victorian Government’s first State of the Sector overview for medical technologies and pharmaceuticals. Medical technologies and pharmaceuticals is a growth sector vital to the future economic prosperity of Victoria and a source of employment for Victorians.
Innovation is critical to developing new sources of growth through creation of new businesses, new jobs and increased productivity. The medical technologies and pharmaceuticals sector provides Victoria with a springboard for innovation-based opportunities.
Since the release of the Victorian Government’s Medical Technologies and Pharmaceuticals Sector Strategy, we have provided key support to industry and manufacturing through the Future Industries Fund. This has included funding for BioCurate and the Medicines Manufacturing Innovation Centre to accelerate the development and commercialisation of new medicines, and further boost Victoria's pharmaceutical manufacturing capability. It has also included provision of grants to a range of Victorian medtech and pharmaceutical manufacturers such as Medical Developments International, Komipharm and DorsaVi. We have also commissioned the first comprehensive analysis of this important sector, culminating in this report.
Australia is one of the world’s leading locations for the development and manufacture of medical technologies, biotechnologies and pharmaceuticals.
Victoria is at the epicentre of this dynamic sector, employing more than 23,000 people, and generating over $12.7 billion in revenue. The sector contributes over $1.35 billion in exports to the Victorian economy, a figure which has doubled since 2011.
Melbourne has a reputation as the leading hub for Australia’s medical technologies industry. The biomedical engineering expertise in the State builds on a long tradition in automotive, aerospace and general manufacturing expertise and is enhanced by significant capabilities in advanced, additive and bio-manufacturing.
With global health care spending projected to grow by over four per cent per year, there is an urgent need for new technologies, goods and services that will improve patient care. This is an enormous and continued economic opportunity for Victoria.
This State of the Sector report demonstrates that the sector’s economic impact is significant and positive. This publication provides us with a better understanding of how the sector is growing and will enable the Victorian Government and the sector to measure our efforts and better understand where we need to direct our energy. Continuing to grow the medical technologies and pharmaceuticals sector will create rewarding, high value, secure jobs for Victorians and help us play a key role in improving health and wellbeing worldwide.
Wade Noonan Minister for Industry and Employment
Jill Hennessy Minister for Health
Philip Dalidakis Minister for Small Business, Innovation and Trade
Introduction
This report brings together four sources of data:
• an analysis of the economic impact of the medtech and pharmaceuticals sector on the Victoria economy, conducted by the Centre for Transformative Innovation (CTI) at Swinburne University, utilising BLADE data1;
• annual survey data, compiled by Blake Industry and Market Analysis Pty. Ltd.;
• market capitalisation information, sourced from the ASX; and
• export commodity trade data, sourced from the IHS Global Trade Atlas.
This publication provides a summary of the results of these reports, together with proprietary government department data as appropriate. Notes on the methodology can be found at the end of this report.
1 Determining the economic impact of the sector is made possible by the Australian Bureau of Statistics Business Longitudinal Data Environment (BLADE). This database is the only comprehensive data of financial operations of every business in Australia and is based on annual business tax file records and survey data. The measure of economic impact, total value added, is calculated by aggregating across all firms in the sector
360 Biolabs
STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
Introduction
In 2013-14, the Sector generated $12.7 billion in revenue and employed 23,000 people.The following table provides a summary of the sector metrics:
Table 1. Summary of sector metrics
Sector revenue $12.7 billion
Sector-value added $2.2 billion
Exports $1.35 billion2
Percentage of Victoria's total state exports
3.5 per cent
Total capital investment $276 million
Number of employees 23,000 employees (18,000 FTE)
Average wage of employees
$74,000 /employee
Source: Centre for Transformative Innovation
2
2 Statistic from the IHI Global Trade Atlas
Describing and defining the sector For the purposes of this report the sector is defined as firms engaged in the following activities:
1. Pharmaceutical manufacturing and development
2. Life science and biotechnology manufacturing and development
3. Medical technology manufacturing and development
4. Vitamins, supplements and topical product manufacturing and development
5. Service providers – contract research organisations, clinical trial providers, etc.
The sector can be defined as firms that are interconnected and that have shared success factors, supporting industries, infrastructure or labour markets. A representative sector supply chain is depicted in blue in Figure 1.
Firms active in the sector in Victoria may be involved in activities from basic science through to wholesale trade. Firms in the sector perform activities across a range of industry sectors defined in the Australian and New Zealand Standard Industry Classifications or ANZSIC codes.3 Please note that relevant activity undertaken in universities and hospitals was excluded from the analysis.4
3 It is not possible to directly use industry level statistics on economic activity collected by the ABS. This is because the sector comprises incomplete parts of several ANZSICs. To measure the impact of the Sector on the Victorian economy, a comprehensive list of relevant active firms was developed.
4 The main reason for excluding universities and hospitals is that it is not possible to separately identify sector relevant activities from the main activities of these organisations (education and health care) which are not part of the sector.
Key findings
7 /
Hudson Institute
Basic Science
Manufacture Wholesale
Imports
ExportsOffshore
Development & Commercialisation
Licence &
FDI
Invention Disclosure & Applied Research
Retail & Health Service
Providers (Pharmacies,
GPs, etc.)
Development & Commercialisation
Figure 1. Representative sector supply chain5
5 Size of circles are not indicative of the relative size of the sectoral component
9 /STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
Size and location of the sectorThe medical technologies and pharmaceuticals sector is largely located in the Melbourne Metropolitan area – 84 per cent of total businesses. There are a large numbers of businesses in the East, South East and CBD, with growing numbers in the West. While the sector is located primarily in greater Melbourne, there are some firms that are located in regional areas, mainly Geelong.
Notably, there are geographical clusters of medical technologies and pharmaceuticals sector firms. These clusters are around the inner metropolitan region, the Clayton and Monash University precinct, the Ringwood/Bayswater area, and the Dandenong/Mulgrave manufacturing precinct, see Figure 2.
Cranbourne
Deer Park
Belgrave
Berwick
Box Hill
Mornington
Bunyip
Tooradin
Melbourne
Bacchus Marsh
Hurstbridge
Craigieburn
Dandenong
Yarra Junction
Caroline Springs
Healesville
Powelltown
Yarra Glen
WarburtonWarrandyte
Werribee
Ocean Grove
Sunbury
Portarlington
Queenscliff Lang Lang
Pakenham
Tullamarine
Lilydale
Melton
Geelong
Heidelberg
Moorabbin
Frankston
Figure 2. Key medtech and pharmaceutical business locations
Source: DEDTJR, Commercial-in-Confidence
The economic impact of the sector
Direct impact/revenueRevenue, operating expenses and value-added for financial years 2013-14 are depicted in Figure 3. These show sector revenue of around $12.7 billion, with an average salary of $74,000 per annum. Operating expenses of $10.5 billion were reported, resulting in total value add to the Victorian economy of nearly $2.2 billion.6
RevenueAccording to Blake, revenue from Victorian companies increased 20.7 per cent in 2015, to approximately $12 billion, see Figure 4. This is broadly consistent with the findings from the Centre for Transformative Innovation.
6 Value added is equal to turnover net of intermediate inputs. This is consistent with the approach for calculating GDP or Gross State Product (GSP).
Re
ven
ue
: 12.
7
Op
era
tin
g e
xp
en
ses:
10
.5
Va
lue
ad
de
d: 2
.17
2.0
0
4.0
6.0
8.0
10.0
12.0
14.0
$b
illio
n
0
2.0
4.0
6.0
8.0
10.0
12.0
14.0
2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
($b
illio
n)
Figure 3. Key economic aggregates for the sector (2013-14)
Figure 4. Total revenue generated by Victorian companies (2015)
Source: Centre for Transformative Innovation
Source: Blake Industry & Market Analysis
11 /STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
ExportsThe sector contributed over $1.35 billion in exports over 2013-14. This is a measure of goods exports only, not licensing, services, IP etc. (Centre for Transformative Innovation). This accounted for just over 3.5 per cent of a Victorian total of $24 billion over the same period.
EXPORT DATA (LONGITUDINAL, AND BY MARKET)
2016 figures indicate that there has been a significant improvement in export figures, driven mainly by growth in pharma sales see Figure 5. The majority of exports go to the USA and Europe. See Figure 6.
Financial year
Pharma exports MedTech exports
2011 2012 2013 2014 2015 2016
Va
lue
of
Vic
tori
a's
Med
Tec
h
& P
ha
rma
Exp
ort
s ($
m)
50 55
7167
77
78
0
300
600
900
1200
1500
605 628
725682
749
1,267
Figure 5. Sector export data (goods exports only, 2016)
Source: IHS Global Trade Atlas: Global Import/Export Commodity Trade Data, 2016
Source: IHS Global Trade Atlas: Global Import/Export Commodity Trade Data, 2016
Figure 6. Annual average exports by market 2011-2016
United States
Europe
South East Asia
East Asia, inc China
MENA
NZ & the Pacific
Canada
Central and SouthAmerica, inc Carribean
South Asiainc India
Africa
Supply chain effectsThe sector also contributes to aggregate demand in sectors that supply intermediate inputs. The CTI Report estimates that the Sector contributes $6.9 billion in upstream demand to other sectors in the Victorian economy.
The detailed breakdown of the distribution of sources of intermediate inputs is presented in Figure 7. Supplying industries are aggregated to the ANZSIC Division level. Transport, Postal and Warehousing is the largest supplying industry group to the sector, supplying nearly $1.5 billion of intermediate inputs. Rental, Hiring and Real Estate Services ($1.2 billion) and Manufacturing ($0.99 billion) are the next largest contributors.7
7 Nearly one fifth of the sectors’ operating expenditure falls under the category Within Sector. This group captures the expenditure on intermediate inputs by the sector from within the sector. Inputs purchased by other firms in the Sector will be reflected in the supplying firm turnover. Therefore, this economic impact has already been captured in the value added measure.
,
$0 $500 $1,000 $1,500 $2,000 $2,500
AN
ZS
IC D
ivis
ion
$million
Within sector: $2,094
Imports: $1,418
Other: $763.88
Retail trade: $210
Construction: $459
Administrative and support services: $555
Financial and insurance services: $593
Manufacturing: $995
Rental, hiring and real estate services: $1,196
Transport, postal and warehousing: $1,526
Electricity, gas, water and waste services: $237
Information media and telecommunications: $454
Figure 7. Supply chain analysis.
Source: Centre for Transformative Innovation
Walter and Eliza Hall Institute
13 /STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
Wages and employmentTotal sector employment is just under 23,000 individuals, with just over 18,000 full time equivalent (FTE) positions (Figure 8). Firms in the sector paid $1.34 billion in remuneration in the year 2013-14. Manufacturing employment in the sector has also steadily increased over time, see Figure 9.
0
1000
2000
3000
4000
5000
6000
7000
8000
9000
10000
Nu
mb
er o
f Em
plo
yees
(H
ead
cou
nt)
1985
1986
1987
1988
1989
199
019
91
199
219
93
199
419
95
199
619
97
199
819
99
200
020
01
200
220
03
200
420
05
200
620
07
200
820
09
2010
2011
2012
2013
2014
2015
Figure 9. Manufacturing employment trends in the sector (2016)
FT
E: 1
8,3
24
He
ad
cou
nt:
22,
89
4
Wa
ge
s: $
1,3
44
$200
$0
$400
$600
$800
$1,000
$1,200
$1,400
$1,600
5,000
0
10,000
15,000
20,000
25,000
$m
illio
n
Nu
mb
er
Figure 8. Wages and employment in the sector (2013-14)
Source: DEDTJR, drawing on ABS data
Source: Centre for Transformative Innovation
Employment ranges for Victorian companies in the sectorEmployment ranges for the surveyed Victorian companies in the sector are summarised in Table 2.8
Capitalisation and listing of the sectorThe aggregate capitalisation of listed Victorian companies in 2015 was $43.9 billion, having risen sharply since 2011, see Figure 10. Note that the key driver of change was CSL, which increased in market value by $5 billion to $40.1 billion from 2006 to 2015. NB: At 26 April 2017, the aggregate capitalisation was approximately $55.2 billion.
8 Blake Industry & Market Analysis Pty Ltd (21 October, 2016), Medical Technology & Pharmaceutical Sector 2015 Final Annual Report. Commercial in confidence.
Table 2. Company employment ranges for Victorian companies surveyed (2015)
Number of employees
Listed companies Private companies Total
<20 16 102 118
20 – 50 8 27 35
50 – 200 8 12 20
200+ 4 4 8
Source: Blake Industry & Market Analysis
Figure 10. Aggregate capitalisation of listed Victorian companies
16.4
21.7
25.423.8
21.4
20.4
27.7
34.1
35.8
38.039.0
43.9
10
15
20
25
30
35
40
45
50
($B
illio
n)
Sept2006
Sept2007
Sept2008
Sept2009
Sept2010
Sept2011
Sept2012
Sept2013
Sept2014
Sept2015
Source: Blake Industry & Market Analysis
STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
VICTORIAN ASX LISTED COMPANIES AND MARKET CAP
36 listed Victorian companies had a market capitalisation at June 30, 2015 of $43.9 billion (up from $39.0 billion in 2014). The number of Victorian life science companies listed on the ASX has fallen since 2008-9 and has remained static since 2011, see Figure 11.
Note that when Sigma Pharmaceuticals Limited and CSL are excluded from the data, market capitalisation has fallen significantly, since 2011, see Figure 12. This is largely as a result of lower investment capital after the Global Financial Crisis.
2.5
3.5
2.0
2.92.8
4.3
3.8
3.8
3.9
3.7
2.92.9
1
1.5
2
2.5
3
3.5
4
4.5
5
($B
illio
n)
Sept2006
Sept2007
Sept2008
Sept2009
Sept2010
Sept2011
Sept2012
Sept2013
Sept2014
Sept2015
Jun2005
Jun2006
Jun2007
Jun2008
Mar2009
Sep2009
Sep2010
Mar2011
Sep2011
Mar2012
Sep2012
Mar2013
Sep2013
Mar2014
Sep2014
Jun2015
42 42
44
4847
44
4241
36 36 36
3435
34 34 34
Figure 11. Number of listed Victorian life science companies (2015)
Figure 12. Capitalisation of listed Victorian life science companies excluding Sigma Pharmaceuticals Ltd and CSL (2015)
Source: Blake Industry & Market Analysis
Source: Blake Industry & Market Analysis
15 /
SHARE OF ASX MARKET CAPITALISATION BY STATE
Victoria dominates company market capitalisation on the ASX, see Figure 13.
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
Pharma MedTech Total
Sh
are
of M
ark
et C
ap
ita
lisa
tio
n (%
)
60.2%45.7%
92.4%
4.0%3.4%
11.6%
28.0%
12.5%
2.2%
20.6%
11.2%
2.9%5.1%
VIC
NSW
USA
NZ
Other Australianstates
Figure 13. Share of ASX market capitalisation by location of registered company offices (June 2016)
360 Biolabs
17 /STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
Total research and development (R&D) investmentR&D spending in Victoria, with the notable exception of CSL and Mesoblast Ltd, has fallen since 2010, see Figure 14.
NATIONAL HEALTH & MEDICAL RESEARCH COUNCIL (NHMRC)
Victoria is the leading state in competitive grant outcomes,9 see Table 3, with almost 42% of total NHMRC funding in 2016.
9 nhmrc.gov.au/grants-funding/outcomes-funding-rounds, accessed February 2017.
Table 3. Outcomes by state and territory for competitive grants awarded in the 2016 application round
State Applications FundedFunded
rate AmountPercentage
of funding
VIC 2,108 421 20.0% $329,655,050 41.8%
NSW 1,525 272 17.8% $227,547,908 28.9%
QLD 825 131 15.9% $111,543,419 14.1%
WA 360 58 16.1% $44,095,650 5.6%
SA 493 64 13.0% $40,617,469 5.1%
ACT 115 25 21.7% $19,731,441 2.5%
NT 33 8 24.2% $10,213,405 1.3%
TAS 60 7 11.7% $5,016,753 0.6%
Total 5,519 986 17.9% $788,421,095
262 283310
416454
528555
653 637 619657
744
835
969
171 190 209
269 284330 321 328 309
267
215 189226 216
100
0
200
300
400
500
600
700
800
900
1,000
2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
R&
D S
pen
d ($
M)
Total Exc. CSL & MSB
Figure 14. Total R&D spending by Victorian companies (2015)
Source: Blake Industry & Market Analysis
Source: NHMRC
Pre-clinical and clinical assets in Victoria
ASSETS BY THERAPEUTIC AREA
Victoria’s strengths in therapeutic development lie in the oncology, infection and immunity and cardiovascular disease areas, see Figure 15.10 Therapeutic areas covered in "other" include endocrinology and regenerative medicine, as well as orphan diseases.
ASSETS: MEDTECH VS DRUG DEVELOPMENT
The majority of clinical assets in development are in pharmaceuticals as opposed to medical devices. This is consistent with the relevant size of the sectors, see Figure 16.11
10 State Government of Victoria, Life Sciences Pre-Clinical and Clinical Development Programs, Melbourne Australia, June 2016 Commercial -in-Confidence.
11 State Government of Victoria, Life Sciences Pre-Clinical and Clinical Development Programs, Melbourne Australia, June 2016 Commercial -in-Confidence.
0
20
40
60
80
100
120
Drug Development Medical Devices
No
of a
sset
s u
nd
er d
evel
op
men
t
ClinicalPre-clinical
103
56
34
112
0
5
10
15
20
25
30
35
40
45
50
No.
of c
linic
al a
sset
s u
nd
er d
evel
opm
ent
22
13
Infe
ctio
us
dis
ease
s
12.59.5
Au
toim
mu
nit
y &
infla
mm
ati
on
69
Met
ab
olic
dis
ord
ers
9.58
Neu
rosc
ien
ce
16
6
Res
pir
ato
ry
48
35
Oth
er
ClinicalPre-clinical
25
On
colo
gy
36
24
Ca
rdio
vasc
ula
r4.5
16.5
Pa
in
4.5
Figure 15. Victorian strengths (June 2016)
Figure 16. Asset development in Victoria – drugs and medical devices (June 2016)
Source: DEDTJR, Commercial-in-Confidence
Source: DEDTJR, Commercial-in-Confidence
19 /STATE OF THE SECTOR | MEDICAL TECHNOLOGIES AND PHARMACEUTICALS
Further information
Further information on the Victorian Government’s medtech and pharmaceuticals sector strategy and current support programs for industry is available at business.vic.gov.au/ support-for-your-business/future-industries.
IDT Australia
Lab 22, CSIRO
Notes on methodology
The variety of sources utilised to produce the report is indicative of the difficulty of assembling the correct set of metrics for assessing the size and economic impact of the sector. In addition, the data sources cover different time points. In 2016, the Department of Economic Development, Jobs, Transport and Resources (DEDJTR) commissioned the Centre for Transformative Innovation (CTI) at Swinburne University to analyse the impact of the medtech and pharmaceuticals sector on the Victorian economy.
The CTI Report12 utilised a novel new methodology, drawing on de-identified firm-level financial data from Business Activity Statements (BAS) collected by the Australian Taxation Office (ATO) and made available by the Australian Bureau of Statistics (ABS), as the BLADE dataset, the most recent data available for analysis relates to financial year 2013-14.13
12 Centre for Transformative Innovation (February, 2017), Economic Impact Analysis – Victorian Medical Technologies & Pharmaceuticals Sector.
13 Due to a lag in availability, the data is from 2013-14
The sector does not fit one single standard industrial classification. It was therefore not possible to evaluate the complete size of the sector using detailed “off-the-shelf” statistics published by the ABS. To measure the impact of the sector, the CTI identified 651 firms with relevant activities in the sector.14 The economic impact of the sector was then measured by aggregating the activity of these firms.15
To enable a more complete picture of the economic impact of the sector on the Victorian economy, DEDJTR also commissioned Blake Industry & Market Analysis Pty Ltd (“Blake”) to furnish a complementary and commercial in confidence report for FY201516 using a different methodology and providing a greater focus on the various companies in the sector. Over 200 businesses in the sector were surveyed and additional information was retrieved through publicly available documents, including company reports, news articles and regulatory filings, as well as financial analysis metrics. In addition, export data has been sourced from the IHS Global Trade Atlas.17
14 A complete list of the firms included in the analysis is included in Appendix A of the CTI Report.
15 The main caveat to the measured direct impact is that operations in Victoria of firms that are based in other states have not been included. Similarly, no adjustment was made for any possible economic activity outside Victoria by Victorian firms. This means the estimates of economic impact presented are conservative.
16 Blake Industry & Market Analysis Pty Ltd (21 October, 2016), Medical Technology & Pharmaceutical Sector 2015 Final Annual Report. Commercial in confidence.
17 IHS Global Trade Atlas: Global Import/Export Commodity Trade Data, 2016.
Imagining and Medical Beamline, Australian Synchrotron, Australian Nuclear Science and Technology Organisation
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