SCORE The Supplemental Complex Repository for Examiners Biotechnology/Chemical/Pharmaceutical...

SCORE

The Supplemental Complex Repository for Examiners

Biotechnology/Chemical/Pharmaceutical PartnershipJune 2006

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What is SCORE?

• Supplemental Complex Repository for Examiners

• Official repository for complex application data (biosequences, mathematical data, design drawings, 3-D protein crystal data, chemical drawing files, search results, etc.)

• Cost-efficient repository for mega information submitted with applications

• Pilot repository for text file wrapper data

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Why SCORE?

• Challenges faced with image-based processing of complex data – Prosecution and Publication

• Images of complex data are not efficient• Complex data must be rendered in proper format

(text, drawing, proprietary software) – Data Management

• Supplemental data must be printed or soft-scanned and manually processed

• Mega portions (possibly 1,000,000+ pages) difficult to store and use

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Accomplishments to Date

• SCORE 1.0 deployed August 2005. Repository is populated with: – All USPTO biosequence listings– Biosequence search results back to June 2005– All design drawings received via electronic filing– QBE search results pilot initiated– Beginning to load artifact backfile– Other complex information as needed

• Interface with eDAN enabled• PAIR interface enabled

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Immediate Future

• Automate data entry of supplemental file wrapper information upon receipt from applicant

• Automate biosequence validation, error processing, and report dissemination

• Automate internal text document handling (e.g., search results)

• Automate data export to publication contractor and public database partner (NCBI)

• Complete Electronic Records Management certification

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Dataflow

Partners

Submission

Bibliographic Database

Publication

USPTO Public Text/

Image Databases

PSIPS (USPTO

publication site for complex information)

Biosequence Database

Partner

Examiner Access via eDAN

Supplemental Repository

Other Databases

Electronic

ImageRepository

PaperSubmission

Biosequence Search

Other Search PLUS

KeywordSearch Results

Public Access via PAIR

3-D, Chemistry, Plant Photos, Computer Code, Designs

SCORETRID1.051806

ApplicationReceipt

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SCORE Long–Term Objectives

• Accept all file formats allowed with applications • Maintain complex data in proper format for use

and export (to search systems, to publication contractor, and/or to public database partners)

• Provide Examiners with multiple display options • Assist with Trilateral exchange of complex data• Support growing mega data storage needs • Support USPTO electronic file wrapper and

electronic workflow solutions

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Examiner Access (eDAN)

Clicking on the SCORE double helix icon opens the SCORE browser and displays the SCORE Table of Contents for this application.

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SCORE Table of Contents

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Automated Biotechnology Sequence Search (ABSS) Results Page

Files may be viewed when the hyperlink is selected.

The file extension identifies the database searched. The header information in the results also identifies the database searched.

Files may be saved to a workstation.

.rge = GenEmbl

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ABSS Search Results Page

This information appears when the file US-10-503-415-1.rge is selected.

These results are from a search of the GenBank/EMBL/DDBJ database.

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ABSS Search Result Example

The top 45 hits are shown in the table.

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ABSS Alignment Example

The top 15 alignments are shown in the results.

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PLUS Search Results Page

Again, files can be either viewed or saved to a workstation.

When the *.east file download button is selected, the EAST application browser is invoked and executes an EAST search.

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EAST Search Results Example

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PLUS Search Results Example

Clip of the 09619479_CLS.txt file.

Clip of the 09619479_CLSTITLES.txt file.

Clip of the 09619479_WDS.txt file.

Clip of the 09619479_QUAL.txt file.

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3-D File Page3-D File Page

The file may be viewed or saved to a workstation.

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SCORE 3-D Text Data Page

The SCORE team is in the process of determining the appropriate 3-D viewing software. An example of the PDB (Protein Data Bank) viewer, providing an example of viewing capabilities, follows.

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PDB Viewer Example

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Accessing PAIR

PAIR can be found via the USPTO web site (www.uspto.gov)

Hyperlink

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SCORE Content via PAIRAfter Application Number entry

The presence of the Supplemental Content tab indicates SCORE content in the file wrapper

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SCORE Content via PAIR

SCORE Contenttab was selected

This application has a Sequence Listingand Search Results

Note the Hyperlinks

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Sequence Listing via PAIR

Once the Sequence Listing is selected, a version may be chosen

The Sequence Listing may also be downloaded

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Sequence Listing via PAIR

Navigation tools for the Sequence Listing are provided

Header information appears withSEQ ID NO: 1

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ABSS Search Results via PAIR

Multiple sequence searches have been performed in this application

A results set may be chosen for viewing or download

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ABSS Search Results via PAIR

Browser functions may be used to navigate the results set

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PLUS Search Results via PAIR

Each version is one set of PLUS (QBE) search results

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PLUS Search Results via PAIR

Search results may be printed

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Computer Program Data via PAIR

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Computer Program Data via PAIR

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Mega Tables via PAIR

PAIR download limit is 650 Mb. Please contact the Office of Public Records for copies of files over this limit.

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Questions?

Lisa J. Hobbs, Ph.D.

Project Manager

Search and Information Resources Administration

571-272-3373

lisa.hobbs@uspto.gov