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School of Dentistry
.
1888First class enrolled
3 year program
22 students
4 faculty
Dr. Edith White followed the gold rush to the Yukon
School Statistics• Student body
– 98 DDS students/class– 10 PASS students/2 classes– 24 BS dental hygiene students/class– 10 MS dental hygiene students/class– 9 dental therapy students/class– 92 residents in 8 advanced education programs
• Faculty– 116 full-time– 181 adjunct
• Professional and support staff– 232 total
Clinical services
Moos Tower – open to the public377 clinical operatories95,514 patient visits per year
Outreach sites: 15,000 patient visits Northpoint Health & Wellness Cntr Center (N. Mpls) CUHCC (S. Mpls) Walker Dental Clinic (S. Mpls) Hibbing Willmar Howard, South Dakota Mobile Dental Unit
Continuing Dental Education: 154 courses per year 7,349 practitioners
Research Training
.
Graduate Program in Oral Biology
MinnCResT (NIDCR T32)
Positions: 11 post-doc 7 pre-doc
Ph.D. students advised by SOD faculty: 18Ph.D. oral biology - 13Other Ph.D. – 5
Summer Research Opportunities
Graduate Program in Oral Biology
.
40th Anniversary in 2009
14 grad students32 Faculty
School of Dentistry
Department of Veterinary Biosciences, College of Veterinary Medicine
Department of Medicine, Medical School.
Department of Microbiology
Department of Neuroscience, School of Medicine
Department of Pediatrics and Department of Genetics, Cell Biology and Development
Department of Pharmaceutics, College of Pharmacy
Director: Mark Herzberg T32DE007288-14 Neuroscience Microbiology and Immunology Cancer Biology Developmental Biology, Molecular Genetics, and Stem Cells Clinical Research Translational Genetics and Communications Disorders Genomics, Proteomics, Structural Biology, and Computational Biology Nanotechnology, Materials Sciences, and Tissue Engineering
.
Summer Research
.
Director: Joel Rudney, Asst. Dean Res.
DDS (DH) students20 students / year
10 week full-time program
Presentations at national and regional meetings
$600,000 fundraising campaign to stabilize funding
Research Funding
.
NIH institutes:
NIDCRNIDANCINIAIDNIGMSNINDSORWH
ARRA funding:
R01 subcontr (2)R21R01 supplementNSF subcontr.GO grant IHI/SON
NSFHRSA/MN
Corporate:3MORMCODentscareAmgen
Funding Sources FY09
.
Total: $ 4,574,143
32%
9%
17%
42%
NIDCR
Other NIH Institutes
Subcontracts
Non-federal
Total: $ 6,278,002
Funding Increase Jun-Nov 2009
$0
$500,000
$1,000,000
$1,500,000
$2,000,000
$2,500,000
$3,000,000
NIDCR Other NIH Inst Subcontracts Non-federal
June $ 4.5M
November $ 6.3M
ARRA: $862,265
Research Areas
Bone Biology Neuroscience, PainMicrobiology, Virology Salivary Proteins Cell BiologyBiomaterials Dental MaterialsImagingImmunologyPeriodontal and Systemic Disease Temporomandibular joint disease Orthodontics Endodontics Dental ImplantsOral SurgeryOral CancerDevelopmental BiologyPublic Health, Preventive Care
Investigators:
School of Dentistry - 5School of Medicine - 15College of Pharmacy - 3School of Public Health - 2College of Veterinary Science - 5Mayo Clinic - 13
Director: Louis Mansky
Bacteriophage phi29
.
1966: Bacteriophage phi29 is identified by Bernard Reilly and Dwight Anderson from soil sample obtained on St. Paul Campus
2009: R01DE003606-39 Morphogenesis of bacteriophage phi29Shelley Grimes
.
Director: Alex Siu-Lun Fok
Works closely with manufacturers to develop and test new dental products and materials in the areas of biomaterials, biomechanics and nano-technology. 3M support since 1991
Virtual Dental Patient: interactive 3D computer rendition of a dental patient.
Artificial Mouth: replicates the effects of a year of chewing in one day (“chews” 300,000 per day)Exhibited in Smithsonian Inst.
Shape Optimization of Dental Restorations
An interdisciplinary project involving engineers and dental scientists.
92% of fractured teeth have been previously restored
Shape optimization based on finite element analysis and biological adaptive growth process led to significant reduction in the stress levels at the tooth–restoration interface.
Conventional
Optimized
Oral Health Clinical Research Center
Director: Bryan Michalowicz
Founded 1990, $2.5 M NIH grant
Multi-purpose research clinic consisting of 10 dental operatories
Translate advances in the basic and applied sciences to the clinical setting
Test new technologies in dental care or delivery
Periodontitis and systemic disease
1UO1 DE018902, Engebretson (PI)
DIABETES AND PERIODONTICS TRIAL
Determine if periodontal treatment improves glycemic control in type II diabetics with moderate to advanced periodontitis
5U01DE014338-06, Michalowicz (PI)
EFFECTS OF PERIODONTAL THERAPY ON PRETERM BIRTH
Treatment of periodontitis in pregnant women improves periodontal disease and is safe but does not significantly alter rates of preterm birth, low birth weight, or fetal growth restriction.
Launched 2002
NIDCR contract $ 5.9 M
Jim Fricton (PI)
Sandra Myers (Repository)
Lois Kehl (Neuroscience)
John Look (Registry)
• A variety of therapeutic approaches have evolved for the relief of TMJD symptoms. Implants have been used primarily to replace the articular disc of the joint and the condylar head of the mandible. Long-term success and functioning of these implants remains a major problem.
A neural pathway for itch
Steve Davidson, Xijing Zhang, Sergey G Khasabov, Donald A Simone & Glenn J Giesler Jr
Department of Neuroscience, Department of Diagnostic and Biological Sciences.
Nature Neuroscience 12, 544 - 546 (2009)
“scratching the cutaneous receptive field of primate STT neurons produced inhibition during histamine-evoked activity but not during spontaneous activity or activity evoked by a painful stimulus, suggesting that scratching inhibits the transmission of itch in the spinal cord in a state-dependent manner.”
News stories carried by NYT, BBC, Reuters, MPR
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