Rbc on Smear

RBC ON PERIPHERAL SMEAR

CONTENTS MORPHOLOGY

DISTRIBUTION

INCLUSIONS

INTERPRETATION OF ABNORMAL RBC

CONCLUSION

MORPHOLOGY

SIZE

RED CELLS COLOUR

SHAPE

Some of the RBC being stained many colors, referred as POLYCHROMATIC cells and those stain shades of bluish grey.

The juvenileRBC those exhibits polychromasia are referred as ‘RETICULOCYTES’

DIAGNOSTIC SCHEME

RBC PROFILE PERIPHERAL SMEAR

ERYTHROCYTOSIS

COUNT OR ANAEMIA

NOT REMARKABLE

ABNORMAL

HYPOCHROMIC ANAEMIA

MEGALOBLASTIC ANAEMIA

HAEMOLYTIC ANAEMIA

HYPOPROLIFERATIVE ANAEMIA

QUALITATIVE HAEMOGLOBINOPATHIES

ACUTE BLOOD LOSS

ANAEMIA IN SYSTEMIC DISEASES

TOTAL RBC COUNT HAEMOGLOBIN ERYTHRON HEMATOCRIT

MCVMCH RBC INDICESMCHC

RDW

RBC PROFILE

RBC STUDY ON P.SMEAR ABNORMAL MORPHOLOGY

ABNORMAL DISTRIBUTION

INCLUSIONS

GRADING

ANISOCYTOSIS

POIKILOCYTOSIS

HYPOCHROMIA

HYPERCHROMIA

POLYCHROMASIA

AGGLUTINATION

ROULEAUX BASOPHILIC STIPPLING

HOWEL-JOLLY BODIES

CABOT RINGS

PAPPENHEIMER BODIES

MALARIAL PARASITE

HEINZ BODIES

GRADING OF ANISOCYTOSIS Type of cell Grade % of RBC/oil

immersion

Anisocytes 1+ 2 - 52+ 5 - 73+ 7 - 124+ 12 - 25

Microcytes 1+ 5 - 202+ 21 - 503+ 51 - 754+ 76 - 100

Macrocytes 1+ 2 - 102+ 11 - 253+ 26 - 504+ > 50

GRADING OF POIKILOCYTOSIS1+ : 1% - 5%

2+ : 6 % - 10%

3+ : 11% - 25%

4+ : >25%

ABNORMAL DISTRIBUTION

RBC INCLUSIONS

RBC INCLUSIONS

CODOCYTES STOMATOCYTES

DACRYOCYTESBURR CELLS

MACROCYTES

MICROCYTES

DIMORPHIC

ABNORMAL PICTURES OF RBC DISORDERS

MICROCYTIC HYPOCHROMIC ANAEMIA MACROCYTIC ANAEMIA

CONCLUSION

CLINICAL FEATURES

PATHOLOGY OF DISEASE

LAB DATA