PRPP synthetase

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PRPP synthetase. Nucleoside phosphorylases. Phosphoribosyl transferases. The committed step of de novo purine nucleotide biosynthesis. Phosphoribosylamine synthase: cooperativity with respect to PRPP concentration & product inhibition. Outline of de novo purine nucleotide biosynthesis. - PowerPoint PPT Presentation

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PRPPsynthetase

Nucleosidephosphorylases

Phosphoribosyltransferases

The committed step of de novo purine nucleotide biosynthesis

Phosphoribosylamine synthase: cooperativity with respect to PRPP concentration & product inhibition

Outline of de novo purinenucleotide biosynthesis

Outline of de novo pyrimidine nucleotide biosynthesis

EnzymesI. Ribonucleotide reductaseII. Nucleotide diphosphate kinaseIII. dCMP kinaseIV. dUTP diphosphohydrolaseV. dCMP deaminaseVI. Thymidylate synthaseVII. FH2 reductase

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