Pf inding chemical information in the Pfizer research environment: SciFinder

Pfinding chemical information in the Pfizer research environment:

SciFinder

By Pamela J. Scott

The NEW Pfizer

The best get better!

http://www.pfizer.com

• Global research facilities• Scientific staff of over 12,000• Industry’s largest R&D budget for 2000: $4.7

billion • 131 compounds in development

SciFinder : Historical Overview Fall 1995: Pilot group of 25 each in Groton &

UK 1/1996: 100 users 1/1998: 831 users

– limited access to SSM 1/1999: 1001 users

– open access to SSM 1/2000: 1419 users 1Qtr 2000:

– links to full-text– links to in-house Doc Delivery

Where We Are In 2000

~1,500 SciFinder users adding 1-5 per week

Countries: Japan, England and United States

Beta testing Y2000 release (in progress) Coordinating efforts and project planning with

new Pfizer sites, looking for best practices

Administration Issues HelpDesk responsibilities:

Daily registration of new users Also software installations & upgrades

My responsibilities: Training & education Communication Alpha, beta tests Schedule upgrades Overall project management

New User Training

~Once a week 1-8 people per class Topics covered:

Support links & online tutorials Preferences TOC CAS database organization & coverage Searching for compounds Keyword searching Setting up Alerts Full-text links & Document Delivery

Advanced Training

Every 6 months Sessions include:

SSM Reaction searching Managing your Alerts

Other Education

Via email notification: New tools Tips & tricks Deleting obsolete Alerts etc.

Web Support Page

To provide overview information, help & assistance when I’m not available.

Streamline the Registration process.

Covers: Scope of SciFinder Registration form “Forgot your password” form Contact information (me, CAS Helpdesk) E-manuals Links to CAS online tutorials

How SciFinder Is Used

41%

23%

10%

6%

6%

6%6% 1%1%

Alerts

Topics Exp

Author Exp

Structure Exp

Substance ID Exp

SSM Exp

RXN Exp

Browse TOC

Doc. ID Exp

More Usage Info

Who is using it? Primarily Discovery small numbers for Development

New surge in Biologists sign-up– also Biochemists, Molecular scientists,

protein chemists

More Usage Info

Global trends: same in UK similar in Japan

Impact on other chemical information products:

Beilstein/CrossFire Aurigin MicroPatent others

New Links To Full-text

Critical link to full-text on an expanding campus

Exploits subscriptions to e-journals

If not accessible, quick link to in-house ordering system

Impact On Document Delivery

35% of Doc Delivery requests were from SciFinder users, and looked like this:

Tombari, D. G.; Moglioni, A. G.; Iglesias, G. Y. Moltrasio. New pterosin-precursor hydrindacenes. Synth. Commun. (2000), 30(12), 2113-2120. CODEN: SYNCAV ISSN:0039-7911. AN 2000:353406 CAPLUS

Leclerc, V.; Beaurain, N.; Depreux, P.; Bennejean, C.; Delagrange, P.; Boutin, J.; Lesieur, D. 5-halobenzothiophene analogues of melatonin: synthesis and affinity for MT1 and MT2 receptors in man. Pharm. Pharmacol. Commun. (2000), 6(2), 61-65. CODEN: PPCOFN ISSN:1460-8081. CAN 133:17342 AN 2000:258120 CAPLUS

Antonini, Ippolito; Polucci, Paolo; Martelli, Sante. Pyrimido[4,5,6-kl]acridines. Synthesis, in vitro cytotoxicity and structure-activity relationships. Anti-Cancer Drug Des. (1999), 14(5), 451-459. CODEN: ACDDEA ISSN:0266-9536. CAN 133:260 AN 2000:228542 CAPLUS

A Special Thank You To:

Information Resources/Groton Chih-Wu Chang Fu-Ning Fung

Information Resources/Ann Arbor Judy Johnson Philipsen Hai Mi

Information Resources/UK Sandra Wood David Wood

Information Resources/Japan Toshihide Kokura

ICS HelpDesk/Groton Peirette Woodward Joe Caputo Susan Carey Chris Thiry