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OpenLAB CDS ChemStation Edition Overview

Jon Welsh Agilent Informatics

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How Does OpenLAB CDS ChemStation Edition Address Other Lab Needs? An Enterprise-wide Chromatography Data system • Fully scalable from stand-alone workstation to Distributed System • Easily connects to Data Store or ECM for central data storage and regulatory

compliance with GLP/GMP and 21 CFR Part 11 • Multi-technique: Control of Agilent GC, LC, CE, LC/MS, CE/MS, SFC • Tight instrument integration • Flexible report generation tools for custom calculations, sequence summary and

single run reporting • Macro language

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OpenLAB CDS Workstation Configuration

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OpenLAB CDS: Networked Workstation Configuration

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OpenLAB CDS: Fully Distributed Configuration

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OpenLAB CDS ChemStation Edition – A Scalable Part of the LI Family Features

• All Data and Methods generated by any version of ChemStation rev. B are compatible.

• The UI and workflow of OpenLAB CDS is very familiar and doesn’t change in scaling or adding Data Store or ECM for storage.

Benefit

• Customers have a smooth migration path from single workstation to a Networked System with or without Data Store / ECM.

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Multi-Technique Instrument Control

Many Instruments - One Enterprise Software

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• One user interface • Lab-at-a-glance view of the lab • Identical look & feel – independent of

the hardware • Easy to learn and use • Central administration • Central place to configure data storage

Roles & Privileges

• ChemStation roles and privileges are managed in OpenLAB Control Panel and can be used without OpenLAB ECM or Data Store.

• Support for local and domain user authorization.

• Grouping of instruments into locations.

• Define access security for each location in the tree.

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Data Organization – What’s in a Result Set?

• The master method is copied at the start of the sequence to create a sequence method.

• Any changes made during data analysis (e.g., during an update of the calibration table) are saved into the sequence method.

• The acquisition method is stored in ACQ.txt.

• The individual Data Analysis Method (DA.M) preserves the last data analysis parameter to re-create the last version of the results for a specific data file.

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Usability: Introducing Workflows

Review View • ChemStation Review View • Uses Intelligent Reporter to show results

Data Analysis View

Recalculation Mode - Flexible • Recalculate peak results in the navigation table with one or several different methods • Shortcut to recalculate all data in the navigation table with a single method • Manually step through navigation table or use auto-stepping to review

Reprocessing Mode - Traceable • Reprocess the sequence with different method(s) to update or modify calibration • Add new or changed methods to result set and reprocess the whole or partial sequence • Store and manage all result and method revisions with sequence/result set

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Review View

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Key Benefit: Preview or print reports without reprocessing and get your reports 10 times faster!

Select report template(s) and data-files and get

immediately answers on complete experiments!

Recalculate Mode

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Any method can be loaded from the tree

“autostepping” toolbar

Switch between Recalculation and Reprocessing Mode

“Recalculate” menu

Key benefit: quickly apply multiple methods to a self-defined set of runs

Reprocess Mode

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New tree with current sequence methods; quickly add master methods to the result set

Key benefit: Easy way to reprocess and recalibrate complete sequence

Switch between modes “sequence reprocessing” toolbar

Self-Assembled Data Sets and Result Sets

Self-assembled Data Set

• Use “Add” functionality to add data from different sources

• Reprocess/recalculate and report over self-assembled set of data assembled from different folders [not possible in strict 21 CFR part 11 workflow!].

Self-assembled Result Set

• A self-assembled data set can be turned into a self-assembled result set.

• Always available for cross-sample calculations and uploading into Data Store or ECM.

• Supports cross-sequence review in 21 CFR part 11 workflow

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• Select data files in the navigation table

Self-Assembled Result Set

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• Select the method and destination folder • Launch Create New Result Set… dialog

Sequence Queuing

• The Run Queue now also supports ChemStation sequences. You can directly schedule a single sequence, or process all sequences given in a Queue Plan.

• Select a sequence template to be added to the queue (online only)

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Run Queue • Single Samples can now

be added to the Run Queue.

• Run Method / Run Sequences are submitted to the queue.

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Queue Planner

• The Queue Planner allows setting up the relevant sequences and queueable pauses in a queue plan

• Load, create and save queue plans (as *.qpl file)

• Available in online and offline

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Queueable pause

Easy Sequence

Native Sequence

METHOD HANDLING

OpenLAB CDS ChemStation Edition

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Method Download

• Upon instrument startup, users are given a choice: • download the ChemStation

method to the instrument • upload the instrument method

to ChemStation • create a new method from

instrument method • A differences viewer highlights

the differences between the ChemStation method and the instrument method.

OpenLAB CDS ChemStation Edition – Acquisition Method Viewer Problem I need to review the Acquisition Method parameters before downloading to the instrument. I do not want to trigger Method Resolution.

Solution Acquisition Method Viewer-provides a way to view the acquisition method parameters.

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OpenLAB CDS ChemStation Edition – Single Sample Workflow • The Navigation Table now shows the acquisition method as

well as the data analysis method.

• A fly-over indicates the path to the data analysis method.

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OpenLAB CDS ChemStation Edition

STORAGE OPTIONS

Storage Option Review

File System

• Simple configuration supports Workstation and Networked Workstation

Data Store

• Compliant workgroup solution: Compliance with GLP/GMP and 21 CFR part 11

• Includes sophisticated search support

ECM

• The Enterprise data repository

• Compliance with GLP/GMP and 21 CFR part 11

• Includes sophisticated search support

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• Download any result set or single run from Data Store (or ECM) to the local ChemStation file system.

• The downloaded data can be reviewed and reprocessed, since the result set contains all necessary files.

Data that have been uploaded to Data Store (or ECM) have a different icon in the tree view.

OpenLAB CDS ChemStation Edition – Integration with Data Store or ECM

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For more Information

OpenLAB CDS ChemStation Edition web page

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Title: Agilent OpenLAB CDS eFamiliarization DVD P/N: M8301-60032 This DVD includes a set of eFamiliarization modules for OpenLAB CDS ChemStation and EZChrom Editions Literature Type: DVD Language: English (currently shipping) Chinese & Japanese (ships in Feb. 2014) Target Audience: Agilent customers who need basic overview of the software operations and functions.

What’s New in OpenLAB CDS A.01.06

Support for Windows 7 and 8

Improvements to sequence handling

• Refreshed Sequence Table [CS]

• Full sequence rollout [CS]

Targeted Customer & Support Enhancements

• Improved bar code handling [CS]

• Recoverable error handling for GC

• Improved display of driver versions

Instrument Control

Intelligent Reporting Updates

OpenLAB Data Analysis A.01.02 • Expand support for HPI • Integration with Data Store

Integration with OpenLAB Data Store A.02.01 • Expansion of database compatibility to

PostgreSQL

OpenLAB CDS Secure ChemStation Workstation [CS] = ChemStation Edition [EE] = EZChrom Edition

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OpenLAB CDS A.01.06 Agilent Restricted

Customer Experience

• Stop the GC and Continue the Sequence

• Recoverable error handling

Continue Abort and Continue Queue Abort

Skip Pause Abort and Continue Queue Abort

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Customer Experience

• Improve customer experience of ChemStation sequence table [CS]

• Sequence rollout [CS]

Barcode Reading – Chain of Custody

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• Enter sample information including the sample name into the sequence table

• 7693 ALS with 7890B reads barcode

• CDS compares the Barcode field (Actual) to the sample name (Expected) and determines mismatched values

• Logic determines whether to inject or not and prints results on the reports

• True = prints “barcode match” • False = prints “barcode

mismatch” ChemStation Edition