Non-Invasive Measurement of Blood Parameters through...

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Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Non-Invasive Measurement of Blood Parametersthrough Fingertip

Amodh Kant SaxenaKumar Abhishek

Ramesh Kumar Sonkar

Department of Electronics and Electrical EngineeringIndian Institute of Technology Guwahati

19 February 2015

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Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Overview

1 Objective

2 Photo Plethysmography

3 Sensor Configuration

4 Design

5 Hardware Part

6 Software Part

7 Result

8 Conclusion

9 Discussion

2 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Objective

This work proposes a low cost method for estimation of bloodparameters using photo-plethysmography (PPG) technique.Data is obtained non-invasively from the fingertip, which isprocessed to estimate heart rate and hemoglobin concentration.Invasive methods of blood parameter estimation tend to betime consuming and resource consuming. Estimation is donevia chemical methods which take time to show results. In thiscase we have shown a method which aids in estimation ofparameters instantly, with limited resource usage.

3 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Photo Plethysmography

• Plethysmographs measure changes in volume.

• PPG or photo-plethysmography is a way of measuringrelative changes in volume.

• PPG can be used for detection of blood parameters, bystudying passage of electromagnetic light rays through theskin.

• Information about blood parameters can be obtainednon-invasively through PPG.

4 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Sensor Configuration

• Consists of an LED which illuminates the skin, and aphotosensor.

• The sensor can be used in two configurations: reflectionand transmission.

• The photosensor measures the light reflected (off thebone) or transmitted (through the skin).

• This work uses the reflection mode.

Figur: Sensor Configurations for PPG Sensor

5 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Design

The work comprises two parts:

• Hardware Part

• Software Part

6 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Hardware Part

Figur: Hardware Component of the Measurement System

7 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Circuit

Figur: Circuit Diagram

8 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

PPG Signal Acquisition

9 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Signal Amplification and Filtering Circuit

10 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Signal Amplification and Filtering Circuit

Figur: Observation of output of Second Stage of Signal Amplificationand Filtering

11 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Peak Detector

12 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Heart Rate and Hemoglobin Estimation

• The heart rate is computed by estimation of the frequencyof the output square wave of the peak detector, in bpm(beats per minute).

• Beer Lambert Law is used to compute the hemoglobinlevels:

where,T is the transmittance; I is the light intensity transmittedfrom the solution; Io is the incident light intensity; ε ismolar extinction coefficient of the solution; c is theconcentration of the solution; l is the length of the liquidthrough which the light passes

13 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Software Part

Figur: Software Component of the Measurement System

14 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Result

Figur: Tabulated Results

15 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Conclusion

In this paper, heart rate and hemoglobin levels of human bloodhave been estimated non-invasively with a good level ofaccuracy. The easy realization of concept and added benefits oflow cost components can help in increasing the availability ofcheap healthcare in remote areas. The technique also promisesa decrease in discomfort and time lag associated withtraditional methods.

16 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

Discussion

Future extension of the work can be done in the followingdirections:

• Measurement of some other blood parameters that can bedone by Photo Plethysmography:

• Blood Pressure• Blood Glucose Level• Respiration Rate• Partial Pressure of Oxygen

• Data can be send by a wireless mode of communicationusing a micro-controller to a standalone computing unit

• Using cloud storage for storage of medical diagnosis history

17 / 18

Non-InvasiveMeasurement

of BloodParameters

throughFingertip

Amodh KantSaxenaKumar

AbhishekRamesh

Kumar Sonkar

Objective

Photo Plet-hysmography

SensorConfiguration

Design

HardwarePart

Software Part

Result

Conclusion

Discussion

References

1 Measurement of Blood Pressure usingPhotoplethysmography, M Asif-Ul-Hoque, Md SabbirAhsan, Bijoy Mohajan, 13th International Conference onModeling and Simulation, UK, 2011

2 Photo-plethysmography (PPG) System, Geert Langereis,Version 2, February 2010.

3 Luminous Intensity of an LED as a Function of InputPower, Sean King, ISB Journal of Physics

4 Microelectronic Circuits : Theory and Applications, AdelS. Sedra, Arun N. Chandorkar, Kenneth C. Smith, OxfordUniversity Press

5 Characteristics of Phototransistors(http://www.johnloomis.org/ece445/topics/egginc/ptchar.html)

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