Musculoskeletal Module II Third Professional Year MBBS 5 …

1

MusculoskeletalModuleIIThirdProfessionalYearMBBS5Weeks

2Year-3Modules

S.NO Module Duration

1 Foundation-II 5Weeks

2 Inflammation&Infection-I 6Weeks

3 Blood&Immunology-II 3Weeks

4 Multi-System-I 4Weeks

5 Musculoskeletal-II 5Weeks

6 Cardiovascular-II

7 Respiratory-II

3TableofContentsYear-3Modules...............................................................................................................................................................2

IntroductiontoModule....................................................................................................................................................6

GeneralLearningOutcomes.........................................................................................................................................6

Knowledge................................................................................................................................................................6

Reinforcement..........................................................................................................................................................6

Pathology.................................................................................................................................................................6

Pharmacology...........................................................................................................................................................6

Communitymedicine...............................................................................................................................................6

Forensicmedicine....................................................................................................................................................7

Medicine...................................................................................................................................................................7

Orthopedic...............................................................................................................................................................7

Dermatology.............................................................................................................................................................7

Radiology..................................................................................................................................................................7

Paeds........................................................................................................................................................................7

Eye............................................................................................................................................................................7

ENT...........................................................................................................................................................................7

Prime:.......................................................................................................................................................................7

Skills:.........................................................................................................................................................................8

Attitude:...................................................................................................................................................................8

THEMESFORMUSCULOSKELETALMODULE....................................................................................................................8

Theme1AchingBones.................................................................................................................................................9

Anatomy...................................................................................................................................................................9

Physiology................................................................................................................................................................9

Pathology.................................................................................................................................................................9

Pharmacology.........................................................................................................................................................10

ForensicMedicine..................................................................................................................................................10

CommunityMedicine.............................................................................................................................................11

Medicine.................................................................................................................................................................11

Orthopedics............................................................................................................................................................12

Radiology................................................................................................................................................................12

Eye..........................................................................................................................................................................12

ENT.........................................................................................................................................................................12

Paeds......................................................................................................................................................................12

Research.................................................................................................................................................................12

BehavioralSciences................................................................................................................................................12

Theme2JointStiffness...............................................................................................................................................12

4Pathology.............................................................................................................................................................12

Pharmacology.........................................................................................................................................................13

ForensicMedicine..................................................................................................................................................14

Medicine.................................................................................................................................................................14

Orthopedics............................................................................................................................................................15

ENT.........................................................................................................................................................................15

Paeds......................................................................................................................................................................15

Research.................................................................................................................................................................15

CommunicationSkills.............................................................................................................................................15

Theme3MuscleweaknessandTrauma....................................................................................................................15

Pathology...............................................................................................................................................................15

Pharmacology.........................................................................................................................................................16

ForensicMedicine..................................................................................................................................................16

CommunityMedicine.............................................................................................................................................17

Medicine.................................................................................................................................................................17

Orthopedic.............................................................................................................................................................18

Paeds......................................................................................................................................................................18

Research....................................................................................................................Error!Bookmarknotdefined.

Theme4SkinRashandItching...................................................................................................................................18

Pathology...............................................................................................................................................................18

Pharmacology.........................................................................................................................................................20

Medicine.................................................................................................................................................................21

Paeds......................................................................................................................................................................21

Research.................................................................................................................................................................21

PathologyPracticals.......................................................................................................................................................22

PharmacologyPracticals................................................................................................................................................22

ForensicPracticals..........................................................................................................................................................22

LearningSites.................................................................................................................................................................23

Listofreferencebooks...................................................................................................................................................23

Pharmacology.............................................................................................................................................................23

Pathology...................................................................................................................................................................23

ForensicMedicine......................................................................................................................................................24

CommunityMedicine.................................................................................................................................................24

Ophthalmology...........................................................................................................................................................24

ResearchandBiostatistics..........................................................................................................................................24

Medicine&Allied.......................................................................................................................................................24

Surgery&Allied..........................................................................................................................................................24

5Otorhinolaryngology................................................................................................................................................24

PaediatricMedicine....................................................................................................................................................24

6IntroductiontoModuleWelcometothemusculoskeletalmoduleII

Conditionsrelatedtomusculoskeletalsystemhaveasignificantvalueinclinicalpractice.Backpain,traumaandviolencearepresentlyquitecommoninPakistan.Conditionslikejointdiseases,bonediseasesanddeformitiesareadditionallyessentialtohaveacommandon.Analogously70%ofthepeoplesuffersfromskindiseasesinsomepartoftheirlifeandmostoftheskininfectionsareendemicindevelopingcountrieslikePakistan.Thereforeit’sadditionallyimportanttogivestudentsessentialknowledgeaboutcommonskinlesionsandexplaintheirclinicalpresentationtounderstandtheimportanceofhealthissuesrelatedtoskinandtheburdenofdisease.

Hencetobetterunderstandthesestates,aswellas theneoplasticand infectiveconditionsof themusculoskeletalsystem including skin, appropriate pathological, microbiological aspects, pharmacological aspects as well aspreventionsandcontrolwillbecoveredinthisspecificmodule.Therelevanceofthevariousimagingmodalities,theimportanceofmedicolegalpracticeswillalsobeputintoprospectivethroughout.

Therewillbeanadditionalcontinualemphasisonapracticalapproachwithregardstothemostcommonconditionsaffectingthemusculoskeletalsystem.

Theimportantaspectsoftheclinicaldiagnosis,radiologicalinterpretation,treatmentandpreventionwillbelikewiseemphasized.

GeneralLearningOutcomes

KnowledgeBytheendofthismodule,studentsshouldbeableto:

Reinforcement• Explainimportantanatomicalandphysiologicalcharacteristicsofmusculoskeletalsystem

Pathology• Explainessentialpathologicalconceptsofdiseasesinvolving

Ø JointsØ BonesØ MusclesØ CartilagesØ SofttissuesØ Skin

Pharmacology• DescribetheclinicalapplicationsofNSAIDsinthetreatmentofmusculoskeletaldisorders• DescribethebasicandclinicalpharmacologyofdrugsaffectingboneandMineralHomeostasis• DescribethebasicandclinicalpharmacologyofdrugsusedtotreatGoutandRheumatoidArthritis• Describethebasicandclinicalpharmacologyofskeletalmusclesrelaxants• Describethedrugsusedfordermatologicaldisorders.

Communitymedicine• Classifyaccidentsandinjuries,burdenofRTAs,preventionandcontrolstrategiesofRTAs• Definepoliomyelitisanddiscusstheepidemiology,prevention,andcontrolofpoliomyelitis• DefineErgonomics,PrinciplesofErgonomics,EpidemiologyofMSKdisordersandtheirprevention• DiscussburdenandpreventionofOsteoporosis,OsteomalaciaandRickets

7Forensicmedicine

• Defineandclassifywounds• DescribetypesofhurtaccordingtoQisasandDiyatAct• Describefirearmandexplosivesinjuries• DescribeRTAs,RailwayandAircraftinjuries• DescribetheMedicolegalaspectsofwounds

Medicine• DescribeOsteoporosisandOsteomalaciaanddevelopitsmanagementplan• DiscussRheumatoidArthritisandAnkylosingSpondylitis• DiscussMyopathies

Orthopedic• Describetypesoffractureandexplaintheopenfractures• Explaintheemergencytreatmentofaninjuredlimb.• Identifyanddescribecommonbenignandmalignantbonetumours.• Describecommonligamentous,tendoninjuriesandcommonspinalfractures

Dermatology• Describethepathologicallesionsofskinandtheirclinicalpresentationwithdifferentialdiagnosis.

Radiology• InterpretnormalX-RaysandX-Raysshowingstructuraldeformities

Paeds• Explainbonepainsandachesinchildren• DiscussCongenital/HereditaryMyopathies

Eye• DescribethebasicAnatomyofEye

ENT• DiscussanatomyofEar,Nose,ParanasalSinusesandOralCavity

Prime:

CommunicationSkills• Dealingwithpatients

BehavioralSciences/Professionalism• AttributesofProfessionalism

Research• StudyDesigns• Researchquestion

8Skills:Bytheendofthismodule,itisacoreobjectivethatstudentsshouldhaveacquiredthefollowingskills:

SpecialPathology• IdentifymorphologicalfeaturesofBasalcellcarcinomaandSquamouscellcarcinoma• IdentifymorphologicalfeaturesofTuberculousosteomyelitis

Pharmacology• WritingaprescriptionforapatientwithRheumatoidarthritis• WritingaprescriptionforapatientwithGout

ForensicMedicine• Identifytypesofmechanicalwound• Identifythecausativeweapon• Identifythemannerofwoundcausation• Issueamedicolegalcertificateforthegivenwound

Orthopedic/Medicine• Acquire a thorough history in relevance to MSK and take focused general examination ofmusculoskeletalsystem.

• Identify,evaluateandinterprettheX-raytodiagnosefractures/musculoskeletalconditions• Discusstheradiologicalcharacteristicsoffracturesandradiologicalcharacteristicsofdislocations

Attitude:Whilenotnecessarilytaughtexplicitly,studentsareexpectedtodevelopfollowingattitudesthroughoutthecourse:

1. Demonstrateteamwork,leadership,punctualityandgoodmanners2. Demonstrate humbleness and use socially acceptable language during academic and social

interactionswithcolleaguesandteachers.3. Makeethicallycompetentdecisionswhenconfrontedwithanethical,socialormoralproblemrelated

toMSKinprofessionalorpersonallife4. Discussethicalissues,socialandpreventiveaspectofhealthcareinthecontextofMSKsystem.

THEMESFORMUSCULOSKELETALMODULE

S.NO Theme Duration4weeks

1 AchingBones 2week(1st&2ndWeek)

2 JointStiffness 1week(3rdWeek)

3 MuscleweaknessandTrauma 1week(4thWeek)

4 SkinRashandItching 1week(5thWeek)

9

Theme1AchingBonesSubject Topic S.No LearningOutcome Hrs

AnatomyImportantAnatomicalCharacteristicsofMSK

1. Discuss important anatomicalcharacteristics of musculoskeletalsystem

1

PhysiologyImportantPhysiologicalCharacteristicsofMSK

2. Discuss important Physiologicalcharacteristics of musculoskeletalsystem

1

PathologyMetabolicdiseasesofbone 3. Describethefollowingmetabolic

diseasesofbonefrompathologicalpointofview:• OsteopeniaandOsteoporosis• PagetDisease(OsteitisDeformans)• OsteomalaciaandRickets

1

FractureandOsteonecrosis

4. Classifyfracturesanddescribehealingprocessinfractures

1

5. Enlistaetiologiesofosteonecrosis(AvascularNecrosis)

6. Describeclinicalfeaturesandmorphologicalfindingsinosteonecrosis

Osteomyelitis 7. Classifyosteomyelitisanddelineateitsetiology,pathogenesis,commonclinicalfeatures,morphologicalfindings,andcomplicationsrelatedtoosteomyelitis

1

BoneTumors 8. Classifybonetumors 1

9. Describethefrequencyofdifferentbonetumorsingeneralpopulation

10. Enlistcommonclinicalfeaturesfoundincommontypesofbonetumors.

11. EnlistkeymorphologicalfeaturesofOsteosarcoma,OsteoidosteomaandOsteoblastoma

Cartilage-FormingTumors 12. Discussthefrequencyofdifferentcartilaginoustumorsingeneralpopulation

1

13. Enlistcommonclinicalfeaturesofcommoncartilaginoustumors

TumorsofUnknownOrigin14. Describeetiology,pathogenesis,and

keyclinico-morphologicalfeaturesofEwing’sSarcomaandGiantCellTumor

1

LesionsSimulatingPrimaryNeoplasms

15. Describekeyclinico-morphologicalfeaturesandessentialpointsinthepathogenesisofFibroma

1

10

PharmacologyNSAIDs 16. Describetheclinicalapplicationsof

NSAIDsinthetreatmentofmusculoskeletaldisorders

1

DrugaffectingBone&MineralHomeostasis

17. Classify drugs used in metabolic bonedisorders

2

18. Enlistcalciumpreparations

19. Describeclinicalusesofcalciumsalts

20. EnlistvitaminDpreparations

21. Describe actions of vitamin D onintestine,KidneyandBone

22. DescribeclinicalusesofvitaminD

23. Describe the mechanism of action,clinical uses and adverse effects ofBisphosphonates

24. Describe the mechanism of action,clinical uses and adverse effects ofcalcitonin

25. Classifydrugsusedtotreatosteoporosis

26. ExplainthemechanismofactionofSERM(Raloxifene)andRANKligand(Denosumab)

ForensicMedicine

Mechanismofproductionofwound

27. Defineandclassifywound 1

28. Describemechanismofactionofwoundproductionassociatedfactors,appearanceandcomplications.

Abrasion 29. Defineandclassifyabrasion

30. Explaintypesofabrasionandmechanismofwoundproductionassociatedfactors,appearance,andcomplication.

31. Differentiatebetweenantemortem&postmortemabrasion.

32. Describethemedicolegalaspectsofabrasion

Bruise 33. Defineandclassifybruise 1

34. Describetypesofbruiseandmechanismofwoundproductionassociatedfactors,appearance,andcomplication.

35. Differentiatebetweenantemortem&postmortemBruise.

36. DescribethemedicolegalaspectsofBruise

11Laceratedwound 37. DefineandClassifylaceratedwound 1

38. DescribetypesoflaceratedwoundandMechanismofwoundproductionassociatedfactors,appearanceandcomplication.

39. Differencebetweenantemortem&postmortemLaceration.

40. DescribethemedicolegalaspectsofLaceratedwound

IncisedWound

41. Defineandclassifyincisedwound 1

42. Describetypesofincisedwoundandmechanismofwoundproductionassociatedfactors,appearance,andcomplication.

43. Differencebetweenantemortem&postmortemIncisedWound

44. Differentiatebetweenincised&laceratedwound.

45. DescribethemedicolegalaspectsofIncisedwound

Stabwounds 46. DefineandclassifyStabwound47. DescribetypesofStabwoundand

mechanismofwoundproductionassociatedfactors,appearance,andcomplication.

48. Differencebetweenantemortem&postmortemstabwound

49. Describethemedicolegalaspectsofstabwound

CommunityMedicine

Ergonomics 50. DescribeErgonomics 1

51. Describetheprinciples&importanceofErgonomicsatworkplace

52. Explaintheepidemiologyofmusculoskeletaldisorders

53. DiscusspreventionandcontrolstrategiesforMusculoskeletaldisorders

Osteoporosis,OsteomalaciaandRickets

54. DiscussepidemiologyandpreventionofOsteoporosis,OsteomalaciaandRickets

1

MedicineOsteoporosisandOsteomalacia

55. DescribeOsteoporosisandOsteomalacia

1

56. ListcommoncausesandriskfactorsofOsteoporosisandOsteomalacia

57. Discussclinicalfeatures,differentialdiagnosisofOsteoporosisandOsteomalacia

1258. EnlisttheInvestigationsforpatient

presentingwithOsteoporosisandOsteomalacia

Orthopedics

Fractures

59. Describeandillustratetypesoffracture,fracturepatterns,displacementandangulationoffracturesinchildrenandadults.

1

60. ExplainopenfracturesDiscussthebasicprinciplesofwounddebridement.

BoneTumours 61. Torecognize,investigateanddescribetheradiologicalfeaturesofcommonbenignandmalignantBoneTumours.

1

RadiologyX-RayInterpretation 62. Identifyandinterpretdifferenttypesof

fractures1

EyeAnatomyofEye 63. DescribeanatomyofOrbit 1

64. DescribeanatomyofEyeBall

ENT Ear 65. Explainanatomyofear 1

PaedsBonepainsandachesinchildren

66. CommoncausesofbonesachesandpainsincludingGrowingpainsinchildren

1

67. DiscussnutritionalRicketscausation,clinicalpresentation,LabandRadiologicalfindingsandprevention

Skeletaldysplasia’s 68. Discussclinicalfeatureanddifferentialdiagnosisofthefollowing• Achondroplasia• Osteopetrosis• OsteogenesisImperfecta

1

ResearchQualitativeandquantitativestudydesigns

69. Listandexplaindifferentstudydesignsthatcanbeusedinquantitativeandqualitativeresearchstudies

3

BehavioralSciences

Attributesofprof 70. Discriminateempathyandsympathy 1

Demonstrateempathyinpatient-healthprofessionalinteraction

Theme2JointStiffness

PathologyOsteoarthritis

71. Describeaetiologyandpathogenesisofosteoarthritis

1

72. Discussclinicalandmorphologicalfeaturesofosteoarthritis

73. Enumeratecomplicationsofosteoarthritis

RheumatoidArthritis74.

DescribeaetiologyandpathogenesisofRheumatoidArthritis

1

13

75. DiscussclinicalandmorphologicalfeaturesofRheumatoidArthritis

76. EnumeratecomplicationsofRheumatoidArthritis

SeronegativeSpondyloarthropathies 77.

ClassifyandexplainSpondyloarthropathies

1

78. DiscusspathogenesisandclinicalfeaturesofAnkylosingSpondylitis

79. DiscusspathogenesisandclinicalfeaturesofReactiveArthritis

80. DiscusspathogenesisandclinicalfeaturesofPsoriaticArthritis

InfectiousArthritis81.

DescribeetiologyandpathogenesisofSuppurativeArthritis

1

82. DiscussclinicalfeaturesandmorphologicalfeaturesofSuppurativearthritis.

83. EnumeratecomplicationsofSuppurativearthritis

84. DescribeetiologyandpathogenesisofMycobacterialArthritis

85. DiscussclinicalfeaturesandmorphologicalfeaturesofMycobacterialArthritis

86. EnumeratecomplicationsofMycobacterialArthritis

RheumaticFever87.

Describekeystructuralfeatures,virulencefactors,modesofpathogenesisanddiagnosisofStreptococcuspyogenes

1

88. Explainetiology,pathogenesis,clinicalfeatures,diagnosis,andcomplicationsofRheumaticFever.

Crystal-InducedArthritis89.

Enlistdifferenttypesofcrystal-Inducedarthritis

1

90. Describekeypointsofaetiology,pathogenesis,clinicalfeatures,morphologicalfeatures,andcomplicationsof:• Gout• CalciumPyrophosphateCrystal

depositionDisease(Pseudo-Gout)

PharmacologyPharmacotherapyofGout 91. Classifydrugsusedtotreatgout 2

92. Describe the role of NSAIDs in thetreatmentofgout

93. Describe the role of Glucocorticoids inthetreatmentofgout

1494. Describe the mechanism of action of

various drugs (Colchicine, Probenecid,Allopurinol, Febuxostat) used in thetreatmentofGout

95. Discusstheadverseeffectsofanti-goutdrugs

96. Describe the drug interactions ofAllopurinolandProbenecid

97. Enlistthedrugscausinghyperuricemia

98. Discuss themechanismbywhichdrugscauseshyperuricemia

PharmacotherapyofRheumatoidArthritis

99. Classify drugs used in Rheumatoidarthritis

3

100. Discuss the role of NSAIDs inRheumatoidArthritis

101. Discuss the role of Glucocorticoids inRheumatoidArthritis

102. DefineandclassifyDMARDs

103. Enlist biological and non-biologicalagents used to treat rheumatoidarthritis

104. Describe pharmacokinetics mechanismof action, clinical uses and adverseeffectsofmethotrexate.

105. Enlist adverse effects and therapeuticusesofDMARDs

ForensicMedicineAgeofWound&Complication

106. Describeeventsassociatedwithwoundhealing

1

107. Differentiatebetweenoldandfreshwound

108. Describeinjuryzoneonthebasisofhisto-chemicalchangesandBiochemicaleventstakingplace.

Qisas&Diyat 109. Definehurt,Wound&injury 1

110. ClassifyhurtaccordingtoInternationallaw

111. TypesofhurtaccordingtoQisas&DiyatAct

112. ExplainPunishments(tazir),compensationandFine(Diyat)

MedicineRheumatoidArthritis 113. DescribeRheumatoidArthritiswithits

clinicalpresentationanddifferentialdiagnosis.

1

AnkylosingSpondylitis 114. DescribeAnkylosingSpondylitiswithitsclinicalpresentationanddifferentialdiagnosis.

15

OrthopedicsBoneandJointInfections 115. Descirbetheaetiology,pathology,

clinicalpresentationandinvestigationsofBoneandJointinfections

1

ENTNose,ParaNasalSinuses&OralCavity

116. DiscussanatomyofNose,Paranasalsinuses&oralcavity

1

PaedsJuvenileIdiopathicarthritis(JIA)

117. DiscusscriteriaforclassificationofJIA

1

Discussitsclinicalfeaturesanddifferentialdiagnosis.

ResearchQualitativeandquantitativestudydesigns

118. Discussandselecttheappropriatestudydesign/approachfortheresearchquestion

1

CommunicationSkills

DealingwithPatients119. Explainimportanceofanswering

questionsandgivingexplanationand/orinstructions

1

Theme3MuscleweaknessandTrauma

PathologyTumorsofadiposetissue 120. Classifysofttissuetumorsandprovidea

briefdescriptionoftheirsalientclinicalfeatures

1

121. Enlistkeymorphologicalfeaturesoflipomaandliposarcoma

FibrousTumors 122. Describeimportantclinico-pathologicalandmorphologicalfeaturesof:• NodularFasciitis• Fibromatoses

1

Muscletumors 123. Classifymuscletumors 1

124. Describeetiology,clinico-morphologicalfeatures,andcomplicationsofRhabdomyosarcoma

125. Describeetiology,clinico-morphologicalfeatures,andcomplicationsofLeiomyoma

126. Describeetiology,clinico-morphologicalfeatures,andcomplicationsofLeiomyosarcoma

127. Describeetiology,clinico-morphologicalfeatures,andcomplicationsofFibrosarcoma

Skeletalmuscleatrophyandmyopathies

128. DescribepathologicalfeaturesofSkeletalMuscleAtrophy

1

129. DescribepathologicalfeaturesofNeurogenicandMyopathicchangesinSkeletalMuscle

130. DescribepathologicalfeaturesofInflammatoryMyopathies

16131. Describepathologicalfeaturesof

Dermatomyositis

132. DescribepathologicalfeaturesofPolymyositis

133. DescribepathologicalfeaturesofInclusionBodyMyositis

134. DescribepathologicalfeaturesofToxicMyopathies

InheritedDiseasesofSkeletalMuscle

135. Describegeneticabnormality,morphologyandclinicalfeaturesofMuscularDystrophies

1

PharmacologySkeletalmusclerelaxants 136. Classifyskeletalmusclerelaxants. 3

137. DescribethemechanismofactionofNon-depolarizinganddepolarizingneuromuscularblockers.

138. Discussthedifferencesbetweendepolarizingandnon-depolarizingskeletalmusclerelaxants

139. Describethetherapeuticusesandadverseeffectsofskeletalmusclerelaxants

140. Describecentrallyactingskeletalmusclerelaxants(Spasmolytics)

141. Namedrugscausingmalignanthyperthermia

142. DiscusstherationaleforuseofDantroleneinthetreatmentofmalignanthyperthermia

143. Discusssuccinylcholineapneaanditsmanagement

ForensicMedicineTransportationAccidents 144. Discussinjuriestothedriver&front

seatoccupantandrareseatoccupant.2

145. DiscussspinalinjuriesincludingWhiplashinjuryandrailwayspine

146. ExplainRailwayinjurieswithmedicolegalsignificance

147. DiscussAircrashaccidents.

FirearmInjuries 148. Describewoundballisticsanditstypes. 3

149. Describeterms/Definitionusedinfirearminjuries,typesofbullets.

150. Explainbasicmechanismoffirearm.

151. Explainrangesoffireinfirearminjuries,bevelingphenomenon,woundproductionmechanism.

17152. Identifytypesofgunpowdersand

ammunitionused.153. Interpretfindingsofinjuriesproduced

bydifferentweapons.154. Explainpatternofidentificationofentry

andexitwound.155. Explaininformationinferredfrom

examinationoffirearmentrywound.InjuriesByExplosives 156. Describemechanismofproductionof

injuriesbybombblast.1

157. Explaindifferentcausesofdeathinblastinjuries.

158. InterpretAutopsyfindingsinexplosionfatalities.

ThermalInjuries 159. DescribeThermalInjuries 1

160. Describetheirclassifications

161. DescribeBurnsandScaldsElectricalInjuries 162. Explainelectrocution 1

163. Typesofelectricalinjuries

164. DescribePMfindings

165. ExplainLightning

CommunityMedicine

Poliomyelitis 166. DefinePoliomyelitis

1

167. DescribetheEpidemiology,determinants&distributionofpoliomyelitis

168. DescribethepreventionandcontrolmeasuresofPoliomyelitis

RoadTrafficAccidents 169. DescribeRoadTrafficAccidents? 1

170. Classifydifferenttypesofroadtrafficaccidentsandinjuries?

171. DescribeandcomparetheburdenofroadtrafficaccidentsinadevelopedcountrywithadevelopingcountrylikePakistan

172. ListandExplaintheriskfactorsofroadtrafficaccidents

173. Explaineffectivepublichealthstrategiesusedatindividualandnationalleveltopreventforroadtrafficaccidents

MedicineMyopathies 174. DefineMyopathy 1

175. EnlistMyopathies(Hereditary&AcquiredMyopathies)

18176. Describetheetiologyandclinical

featuresofMyopathies177. PlaninvestigationsforMyopathies

OrthopedicApplicationofCast 178. Explaintheemergencytreatmentofan

injuredlimb.1

179. ExplainemergencyimmobilizationtechniquesoftheNeck,Spinalcolumnandlimbs.

180. Describeanddiscussthebasicprinciplespertainingtoapplicationofacast,thecomplicationsofcastapplication.

181. Discusstheprinciplesofathree-pointpressuresysteminacast.

SoftTissueInjuries,SpinalInjuries

182. Describethecommonligamentousandtendoninjuriesandadviseappropriatemanagement

1

RecognizecommonSpinalfractures,andprovideappropriateinitialmanagement

PaedsCongenital/HereditaryMyopathies

183. Discusscommoncongenitalandhereditarymyopathies,theirgenetics,causation,clinicalpresentation,diagnosis.

1

DucheneMusculardystrophy(DMD)

184. DescribeDMD,itsclinicalpresentationanddifferentialdiagnosis.

1

Theme4SkinRashandItching

PathologyImportantpathologicalterms

185. Definethefollowingskinlesionsanddescribethesewithrespecttotheiretiologiesandgrossmorphologicalfeatures.• Macule• Papule• Nodule• Plaque• Vesicle• Bulla• Blister• Pustule• Scale• Lichenification• Excoriation• Hyperkeratosis• Parakeratosis• Acanthosis• Dyskeratosis• Acantholysis

1

19• Papillomatosis• Lentiginousspongiosis• Urticaria• Pemphigus• Bullouspemphigoid• Warts

Eczematousdermatitis 186. Classifyeczematousdermatitis 1

187. Describethemorphologicalandclinicalfeaturesofacuteeczematousdermatitis

188. Describetheetiologyandpathogenesisof• Contactdermatitis• Atopicdermatitis• Drugrelatedeczematousdermatitis• Photoeczematuseruption• Primaryirritantdermatitis

Erythemamultiforme 189. Listtheconditionswhichareassociatedwitherythemamultiformeanddescribeitsclinicalfeatures

1

Psoriasis 190. Describetheetiopathogenesis,morphologicalandclinicalfeaturesofpsoriasis

1

Pre-malignantepitheliallesions

191. Listthepre-malignantepitheliallesions(Epidermal)• Listthepredisposingfactorsforsquamouscellcarcinomaofskin

• Differentiatesquamouscellcarcinomafrombasalcellcarcinomaonthebasisofmorphologyandclinicalfeatures

1

NevocellularNeviandMalignantMelanoma

192. ListtypesofNevocellularNevi(CongenitalNevus,bluenevus,Spitz’sNevus,halonevusdysplasticnevus)alongwiththeirclinicalsignificance.(Dermal)• Describetheclinicalandmorphologicalfeaturesofdysplasticnevi

• Describemalignantmelanomawithrespecttofrequentsiteoforigin,clinicalandmorphologicalfeatures.

1

Viralskininfections 193. Describethefollowingviralskininfectionsincontextofetiopathogenesis:• Herpessimplexvirus• Herpeszostervirus

1

20Fungalskininfections

194. Classifyanddescribethefollowingfungalskininfectionsincontextofetiopathogenesis:• Tinea• Candida

1

Skinandsofttissueinfections

195. Describethefollowingskinlesionsincontextofethiopathogenesisanddiagnosis• Impetigo• Cellulitis/Erysipelas• Folliculitis• SkinAbscess(Furuncle&Carbuncle)• NecrotizingSoftTissueInfections

1

PharmacologyDrugsusedfordermatologicaldisorders

196. Classifydermatologicalpreparations 2

197. Enlisttopicalantibacterial,antifungal&antiviralpreparations.

198. Describeclinicalusesandadverseeffectsoftopicalantibacterial,antifungalandantiviraldrugs.

199. Discussoraltreatmentofcandidiasisdermatophytosisandonychomychosis.

200. Describevariousacnepreparationsandantibioticsusedtotreatacne.

201. Enlistclinicalusesofimmunomodulators(Imiquimod,Tacrolimus)relatedtoskindiseases.

202. Enlistectoparasiticides

203. EnlistclinicalusesandadverseeffectsofPermethen.

204. DiscussdrugtreatmentofScabies&Pediculosis.

205. Describethemechanismofactionandadverseeffectsofvariousagentsusedforpigmentationdisorders

206. Describetheclinicalusesandadverseeffectsofdrugsusedforthetreatmentofpsoriasis.

207. Describeclinicalusesandadverseeffectsoftopicalcorticosteroids

208. Enlistdermatologicaldisordersresponsivetotopicalcorticosteroidsrankedinorderofsensitivity.

209. Discusskeratoyticagents,antipruriticagents,trichogenicandantitrichogenicagentsanduseofantineoplasticagentsintopicalconditions

21

MedicineImportantpathologicaltermswithClinicalpresentations

210. EnlistandexplaintheclinicalpresentationofthefollowingskinLesions:

• Macule• Papule• Nodule• Plaque• Vesicle• Bulla• Blister• Pustule• Scale• Lichenification• Excoriation• Hyperkeratosis• Parakeratosis• Acanthosis• Dyskeratosis• Acantholysis• Papillomatosis• Lentiginousspongiosis• Urticaria• Pemphigus• Bullouspemphigoid• Warts

1

Pre-malignantskinconditions

211. Enlistthepre-malignantskinconditionsExplaintheirdifferentialdiagnosisonthebasisofclinicalpresentationsEnlisttherelevantinvestigations

1

Malignantconditionsofskin

212. Enlistthemalignantconditionsofskin(squamousandbasalcellcarcinoma)ExplaintheirdifferentialdiagnosisonthebasisofclinicalpresentationsEnlisttherelevantinvestigations

NevocellularNevi 213. ListthetypesofNevocellularNevianddiscusstheirdifferentialdiagnosisonthebasisoftheirclinicalpresentations.Enlisttherelevantinvestigations

PaedsJuvenileDermatomyocytis(JDM)

214. DiscussdiagnosticcriteriaofJDM

1

Discussitsclinicalfeaturesdifferentialdiagnosis

ResearchQualitativeandquantitativestudy3

215. WriteaproposalforresearchprojectusingKMUorCPSPguidelinesoranyotherstandardguidelines

7

22

PathologyPracticals

Week Topic Practical

Week1 Tuberculousosteomyelitis Identifygrossandmicroscopicmorphologicalfeaturesoftuberculousosteomyelitis

Week2 Osteogenicsarcoma,Osteoclastomaandchondrosarcoma

Identifygrossandmicroscopicmorphologicfeaturesofosteogenicsarcoma,osteoclastomaandchondrosarcoma

Week3 ASO(AntiStreptolysinO)test PerformASO(AntiStreptolysinO)testbylatexagglutinationtechnique

Week4 TumorsofSkin Identifygrossandmicroscopicfeaturesof• Squamouscellcarcinoma• Basalcellcarcinoma

PharmacologyPracticalsWeek Topic Practical

Week1 Gout WriteprescriptionforGout

Week2 RheumatoidArthritis WriteprescriptionforRheumatoidArthritis

Week4 DrugsusedtotreatDermatologicalDisorders

Writedownprescriptionforscabies.WritedownprescriptionforPsoriasis

ForensicPracticalsWeek Topic Practical

Week1 Examinationofwoundandweapon

• Abrasion• Bruise• Laceration• Incisedwound• QisasandDiyatmodels/• Duraprintsofinjuries

Week2 Examinationofwoundandweapon

• Stabwound• Fracture• Displacement• QisasandDiyatmodelsofinjuries/multimediaslidesremaining

Week3 Examinationofwoundandweapon

Firearminjuries/WeaponsIdentificationofbullets

Week4 Writingamedicolegalcertificate

MedicolegalreportwritingincaseoffirearmInjuries

23LearningSites

• Digitallibrary• VirtualLearningEnvironment(VLE)• Ambulatorycaresettingswhichmaybeoutsidethehospital• AccidentandEmergency/Casualtydepartments• ClinicalSkillsLaboratory• CommunitySettings• ElectivesinownandotherInstitutions• ExperimentalLaboratories• HospitalWards• OutPatientDepartments• MedicalCollegesetting

ListofreferencebooksRECOMMENDEDBOOKS

PharmacologyTextBooks

1. BasicandClinicalPharmacologybyKatzungBG,MastersSB,TrevorAJ,14thEdition. 2. Lippincott’sIllustratedReviews:Pharmacology,ClarkMA,FinkelR,ReyJA,WhalenK,7thEdition.

ReferenceBooks:

1. Goodman&Gilman’sThePharmacologicalBasisofTherapeutics,BruntonLL12thEdition.

PathologyTextBooks

1. RobbinsPathologicBasisofDisease

ReferenceBooks:

1. Walter&Israel’sGeneralPathology"2. HarshMohan's"TextbookofPathology".3. PathologyIllustrated4. StefanSilbernagl’s"ColorAtlasofPathophysiology"5. Muir'sTextbookofPathology

TextbookforMicrobiology

1. Jawetz,Melnick&Adelberg's"MedicalMicrobiology"

ReferenceBooks:

1. Levinson's"MedicalMicrobiology&Immunology"2. SherrisMedicalMicrobiology3. Lippincott'sIllustratedReviews:Microbiology

24ForensicMedicineTextbooks:1.CKParikhneweditionReferenceBooks:

1. NasibRAwan2. KrishanVij3. Smartseries(SSS)ForensicMCQswithexplanation4. GazettePakistanPenalCode(PPC)5. VVPillayandRajeshBardale

CommunityMedicineTextbooks:

1. PublicHealth&CommunityMedicinebyShahIlyasAnsari;8thEdition2. ParksTextbookofPrevention&SocialMedicinebyK.Park;24thEdition

OphthalmologyTextbooks:

1. Parsons’DiseaseoftheEYE

ReferenceBooks:

2. ShortKanski3. ClinicalOphthalmologyShafiMJatoi

ResearchandBiostatistics1. Asynopsisofepidemiologyandbasicstatistics(AliMuhammadMir)2. Statissticsatsquareone(TDVSwinscow)3. Essentialsofresearchdesignandmethodology.(GeoferryMarczyk)4. Theessentialsofclinicalepidemiology(RobertH)

Medicine&Allied1. KumarandClarkforMedicine8thedition20122. Davidson

Surgery&Allied1. BaileyandLove.ShortPracticeofSurgery25thedition20082. CurrentSurgicalDiagnosisandTreatment13thedition2009

Otorhinolaryngology1. PLDhingra7thedition2. Cumingstandards,ENT

PaediatricMedicine1. Textbookofpaediatrics,Pakistanpaediatricsassociation2. Essentialsofpaediatrics,Nelson,Eightedition3. Basisofpaediatrics,Pervezakbarkhan,Ninthedition

25