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Dr. N. SRIDHAR GOUD (PhD, M. Pharm., MBA)Genius Book Record Holder
Postdoctoral Fellow,
Department of Neuroimaging and Interventional Radiology
National Institute of Mental Health & Neuro Sciences (NIMHANS),
Bengaluru-560 029, India.
Email: nsr4069@nimhans.ac.in
For Pharma Graduates & GPAT Aspirants
Date: 11/07/2020
Medicinal ChemistryANS
Structures of direct acting parasympathomimetics
Direct acting parasympathomimetics
Structural Activity Relationship (SAR) of Ach:
Stereochemistry (conformers) of Ach:
2. Indirect Acting Parasympathomimetics (Anti-cholinesterases)
Structures of indirect acting parasympathomimetics
Reversible Agents Irreversible Agents
NH2
NH2
1. Mechanism of Ach on Hydrolysis process 2. Mechanism of Reversible inhibitor
3. Mechanism of Irreversible inhibitor 4. Reactivating AchE using 2-PAM
3. Sympathomimetics
3. Sympatholytics
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