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Mechanics of the Unusual Basilar Membrane in Gerbil. Santosh Kapuria, IIT Delhi Charles Steele, Stanford Sunil Puria, Stanford. Microstructure of BM. Detailed anatomy Guinea pig: S Iurato (1962) Cat: LM Cabazudo (1978) Gerbil: Schweitzer L, Lutz C, Hobbs M, Weaver SP (1996). - PowerPoint PPT Presentation
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1Mechanics of the Unusual Basilar Membrane in GerbilSantosh Kapuria, IIT DelhiCharles Steele, Stanford Sunil Puria, Stanford
2Microstructure of BMDetailed anatomyGuinea pig: S Iurato (1962)Cat: LM Cabazudo (1978)Gerbil: Schweitzer L, Lutz C, Hobbs M, Weaver SP (1996)Point load measurementsHuman: Bksy (1960)Guinea pig: Gummer WA, Johnstone BM, Armstrong NJ (1981) Miller, C (1985)Gerbil: Olson EE, Mountain DC (1994) Naidu, RC, Mountain DC (1998) Emadi G, Richter CP, Dallos P (2004)
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Iurato 1962,gp4I- Beam
Beam with constraints5
6Gerbil organ of CortiArc of BMEdge, et al. (1998)
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Gerbil OC (Corrales, 2006)78Beam model for BM
9Arch model
10Buckling of arch
Olson and Mountain 1994 11
Emadi et al. 200412
13Emadi, et al. (2004)
Point load on arch14
15Pressure loading without Pillar stiffness
16Frequency map
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18Fast4 model of OC
Gerbil 2.75 mm, 1 kHz, wavelength = 10 mm19
Gerbil 2.75, with pressure amplitudes20
Gerbil at 2.75 mm, add axial flow amplitudes21
Gerbil at 2.75 mm, add axial flow amplitudes with viscosity22
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Gerbil at BF, add axial viscosity24AcknowledgementFulbright Fellowship to SKNIH RO1 DC00791025Close up, showing cilia and tip links
2607/07/2011Lubrication theoryHSTMIHC tip of ciliumgapTMgapHSqHSqTMpressL1pressISFluid displacement FDFDgapHSgapTM= pressL1 pressISqHSqTMperm*d/dtEdge, et al. (1998)
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