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ICP Mass Spectrometers
with DRC technology
by Keith Hutchison
ICP Mass Spectrometers
with DRC technology
by Keith Hutchison
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Flame + THGA Zeeman
Flame + HGA Furnace
Dedicated THGA Zeeman Furnace (no flame)
Flame (opt. HGA Furnace)
Flame (opt. HGA Furnace)
High-end Flame/
Furnace
Entry-level Flame
(Furnace)
Price
Fea
ture
s/P
erfo
rman
ce
ELAN 9000
ELAN DRC-e
ELAN DRC II
FIMS
AAnalyst 200
AAnalyst 400
AAnalyst 600
AAnalyst 700
AAnalyst 800
Optima 2100DV
Optima 5100DV
Optima 5200DV
Optima 5300V
Conventional ICP-MS system
DRC Technology Systems
Robust basic system
Robust HF resistant sample intro DRC system
Lowest BEC, Highest S/B
Hybrid system
Simultaneous Systems
Lower Cost system
Dual view, single detector
Dual view, single detector + extended λ
Vertical torch/Radial View, dual detector
Dual view, dual detector Optima 5300DV
AA
ICP
-OE
SIC
P-
MS
Dedicated Hg CVAA)
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ELAN Product History
ELAN 250 1983ELAN 500 1987ELAN 5000 1990ELAN 6000 1994ELAN 6100 & DRC 1999ELAN DRC Plus 2001ELAN 9000 & DRCII 2002DRC-e 2003Design Enhancements 200521CFR Part 11 s/w 2005Chromera speciation s/w 2005ELAN 3.4 software 2007
ICP-MS 25 Years Mature
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ELAN Product Line
ELAN 9000• Rugged and
reliable• Designed for
routine, high throughput labs
• Proven methodology for environmental, clinical and geochemical applications
ELAN DRCII
• Targeted at ultra-trace analyses
• Ideal for research-oriented applications
• Exciting potential for other application areas
ELAN DRCELAN DRC --ee
��Targeted at trace Targeted at trace analysisanalysis
��Designed for routine, Designed for routine, high throughput labshigh throughput labs
��Potential for lower Potential for lower detection limits and detection limits and reduced interferencesreduced interferences
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Schematic Diagram of ICP-MS: ELAN 9000
Detector
ShadowStop
Turbomolecularpumps
Roughing pumps
Ar gas in
Main Q-poleDC + AC ( U + Vcosωωωωt )
E-LensPre-filterAC only ( V cosωωωωt )
+++
++++
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A little review…
The quadrupole is a mass filter!It’s a sequential scanning device,
ramping through the periodic table from low to high mass in about 1/100th second.
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Common ICP-MS Spectral Interferences
POLYATOMIC SPECIES
INTERFERED ANALYTE
12C15N, 12C14NH 27Al38Ar1H 39K40Ar 40Ca35Cl16O 51V35Cl16O1H 52Cr36Ar16O 52Cr40Ar12C 52Cr38Ar16O1H 55Mn40Ar16O 56Fe40Ar16O1H 57Fe40Ar35Cl 75AsArAr 80Se
What is produced in an argon plasma?What is produced in an argon plasma?
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Schematic Diagram of ICP-MS: ELAN 9000
Detector
ShadowStop
Turbomolecularpumps
Roughing pumps
Ar gas in
Main Q-poleDC + AC ( U + Vcosωωωωt )
E-LensPre-filterAC only ( V cosωωωωt )
+++
++++
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Schematic Diagram of ELAN DRCReaction
gas in
Detector
Autolens
Shadow stop
DRC
Turbo pump
Roughing pump
Q-pole mass filter
Pre-filter
Ar gas in
++
++
+++
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100
ppt S
tand
ard
in W
ater
with
out
Rea
ctio
n G
as
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100
ppt S
tand
ard
in W
ater
Usi
ng
Rea
ctio
n G
as
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Robust Ion Lens System of ELAN DRC
Neutral species from plasma
DRC cell ( U + V cos ωωωωt )±±±± 150 v
ShadowStopGrounded
AutoLens
M+
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Snap in lens mount
Shadow stop sits on posts. Two fingers to remove a nd replace Shadow stop sits on posts. Two fingers to remove a nd replace lens mount. Retrolens mount. Retro --fit able onto existing instruments.fit able onto existing instruments.
Snap out and Snap inSnap out and Snap in
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What’s New in ELAN v3.4 Software:DRC MD: A New DRC Method
Development Tool
• Simultaneous two-parameter optimization• The ELAN software automatically runs the required s olutions and
selects the best cell conditions
~ DRC Method Development has never been easier!• Outputs results to automatically create a quantitat ive method• Allows you to reprocess previous results with modif ied criteria
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High Throughput Sample Analysis with the SC-FAST and ELAN ICP-MS
High Throughput Sample Analysis with the SC-FAST and ELAN ICP-MS
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What is FAST?
• A Complete Sample Introduction System~ Autosampler~ Switching valve~ On-Line addition of internal standards~ PFA-ST nebulizer~ Peltier-cooled spray chamber
• Direct Nebulization Using Flow Injection~ Filled sample loop takes the role
of the sample vial~ Solution nebulized continuously
as the sample loop empties
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Benefits of the SC-FAST
• High Throughput~ Reduce uptake, stabilization, and rinsing time~ High speed vacuum loading of sample~ Eliminate sample contact with peristaltic pump tubing~ Probe is rinsed while sample is being analyzed
• Constant Sample Flow Rate
• Stable QC
• Integrated with ELAN Software
SC-FAST saves argon, electricity, and reduces consu mables costs.
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Steps in an ICP-MS Analysis
• Autosampler Movement
• Sample Uptake Time
• Plasma Stabilization Time
• Measurement Time
• Rinse Time
Events in Blue are Significantly Shortened
with the SC-FAST
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Normal ICP-MS Sample Introduction
-12 to -48 RPM
Sample passes through peristaltic pump tubing.
On-Line Addition of Internal Standard
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SC-FAST ICP-MS Sample Introduction
-8 RPM
On-Line Addition of Internal Standard
No contact between sample and peristaltic pump tubing.
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USEPA Methods Included
• Turnkey USEPA Methods included
~ 200.8
~ 6020• Prepared specifically for the ELAN
• Time tested for over ten years
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